☆ 4.6 Review

Interferons-Implications in the Immune Response to Respiratory Viruses

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Functional Comparison of Mx1 from Two Different Mouse Species Reveals the Involvement of Loop L4 in the Antiviral Activity against Influenza A Viruses

Judith Verhelst et al.

JOURNAL OF VIROLOGY (2015)

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Article Virology

Protection from Severe Influenza Virus Infections in Mice Carrying the Mx1 Influenza Virus Resistance Gene Strongly Depends on Genetic Background

Dai-Lun Shin et al.

JOURNAL OF VIROLOGY (2015)

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Article Multidisciplinary Sciences

Life-threatening influenza and impaired interferon amplification in human IRF7 deficiency

Michael J. Ciancanelli et al.

SCIENCE (2015)

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Article Virology

Influenza virus activation of the interferon system

Marian J. Killip et al.

VIRUS RESEARCH (2015)

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Article Respiratory System

Alveolar macrophages support interferon gamma-mediated viral clearance in RSV-infected neonatal mice

Katherine M. Eichinger et al.

RESPIRATORY RESEARCH (2015)

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Review Immunology

Type I interferons in infectious disease

Finlay McNab et al.

NATURE REVIEWS IMMUNOLOGY (2015)

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Article Respiratory System

Pulmonary arterial hypertension in patients treated with interferon

Laurent Savale et al.

EUROPEAN RESPIRATORY JOURNAL (2014)

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Article Immunology

The CD4 T cell response to respiratory syncytial virus infection

Allison F. Christiaansen et al.

IMMUNOLOGIC RESEARCH (2014)

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Article Immunology

CD4+ T Cells from Human Neonates and Infants Are Poised Spontaneously To Run a Nonclassical IL-4 Program

Katrin Hebel et al.

JOURNAL OF IMMUNOLOGY (2014)

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Article Immunology

Attenuation of Respiratory Syncytial Virus-Induced and RIG-I-Dependent Type I IFN Responses in Human Neonates and Very Young Children

Nico Marr et al.

JOURNAL OF IMMUNOLOGY (2014)

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Article Infectious Diseases

Interferon lambda 1-3 expression in infants hospitalized for RSV or HRV associated bronchiolitis

Carla Selvaggi et al.

JOURNAL OF INFECTION (2014)

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Article Virology

Limited Type I Interferons and Plasmacytoid Dendritic Cells during Neonatal Respiratory Syncytial Virus Infection Permit Immunopathogenesis upon Reinfection

Stephania A. Cormier et al.

JOURNAL OF VIROLOGY (2014)

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Review Immunology

Ontogeny of early life immunity

David J. Dowling et al.

TRENDS IN IMMUNOLOGY (2014)

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Article Multidisciplinary Sciences

Viral suppressors of the RIG-I-mediated interferon response are pre-packaged in influenza virions

Swantje Liedmann et al.

NATURE COMMUNICATIONS (2014)

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Article Education, Scientific Disciplines

Pattern recognition receptors in innate immunity, host defense, and immunopathology

Rahul Suresh et al.

ADVANCES IN PHYSIOLOGY EDUCATION (2013)

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Review Pharmacology & Pharmacy

IFN- subtypes: distinct biological activities in anti-viral therapy

K. Gibbert et al.

BRITISH JOURNAL OF PHARMACOLOGY (2013)

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Article Infectious Diseases

Role of human Toll-like receptors in naturally occurring influenza A infections

Nelson Lee et al.

INFLUENZA AND OTHER RESPIRATORY VIRUSES (2013)

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Article Cell Biology

IL-4Rα on CD4+ T cells plays a pathogenic role in respiratory syncytial virus reinfection in mice infected initially as neonates

Dahui You et al.

JOURNAL OF LEUKOCYTE BIOLOGY (2013)

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Article Virology

Respiratory Syncytial Virus G Protein CX3C Motif Impairs Human Airway Epithelial and Immune Cell Responses

Tatiana Chirkova et al.

JOURNAL OF VIROLOGY (2013)

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Review Microbiology

Mx Proteins: Antiviral Gatekeepers That Restrain the Uninvited

Judith Verhelst et al.

MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS (2013)

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Article Multidisciplinary Sciences

Respiratory Syncytial Virus Induced Type I IFN Production by pDC Is Regulated by RSV-Infected Airway Epithelial Cells, RSV-Exposed Monocytes and Virus Specific Antibodies

Marcel A. Schijf et al.

PLOS ONE (2013)

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Article Multidisciplinary Sciences

Neonatal antibody responses are attenuated by interferon-γ produced by NK and T cells during RSV infection

John S. Tregoning et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)

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Article Microbiology

Correction: Systems Analysis of a RIG-I Agonist Inducing Broad Spectrum Inhibition of Virus Infectivity

Marie-Line Goulet et al.

PLoS Pathogens (2013)

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Review Immunology

Innate Immune Function by Toll-like Receptors: Distinct Responses in Newborns and the Elderly

Tobias R. Kollmann et al.

IMMUNITY (2012)

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Article Virology

Interferon-Inducible Protein Mx1 Inhibits Influenza Virus by Interfering with Functional Viral Ribonucleoprotein Complex Assembly

Judith Verhelst et al.

JOURNAL OF VIROLOGY (2012)

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Article Multidisciplinary Sciences

Respiratory Syncytial Virus NS1 Protein Colocalizes with Mitochondrial Antiviral Signaling Protein MAVS following Infection

Sandhya Boyapalle et al.

PLOS ONE (2012)

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Article Biochemistry & Molecular Biology

The influenza virus PB1-F2 protein has interferon antagonistic activity

Sabine E. Dudek et al.

BIOLOGICAL CHEMISTRY (2011)

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Review Biochemistry & Molecular Biology

The Interferon Inducible Gene: Viperin

Katherine A. Fitzgerald

JOURNAL OF INTERFERON AND CYTOKINE RESEARCH (2011)

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Article Virology

Antiviral activities of ISG20 in positive-strand RNA virus infections

Zhi Zhou et al.

VIROLOGY (2011)

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Article Virology

Type-III interferon, not type-I, is the predominant interferon induced by respiratory viruses in nasal epithelial cells

Tamaki Okabayashi et al.

VIRUS RESEARCH (2011)

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Review Virology

Induction and evasion of type I interferon responses by influenza viruses

Adolfo Garcia-Sastre

VIRUS RESEARCH (2011)

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Review Virology

Pattern Recognition Receptors and the Innate Immune Response to Viral Infection

Mikayla R. Thompson et al.

VIRUSES-BASEL (2011)

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Article Microbiology

The Influenza Virus Protein PB1-F2 Inhibits the Induction of Type I Interferon at the Level of the MAVS Adaptor Protein

Zsuzsanna T. Varga et al.

PLOS PATHOGENS (2011)

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Review Immunology

Therapeutic targeting of respiratory syncytial virus G-protein

Lawrence M. Kauvar et al.

IMMUNOTHERAPY (2010)

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Editorial Material Biochemistry & Molecular Biology

Interferon-Lambda: A New Addition to an Old Family

Raymond P. Donnelly et al.

JOURNAL OF INTERFERON AND CYTOKINE RESEARCH (2010)

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Article Virology

Lambda Interferon Is the Predominant Interferon Induced by Influenza A Virus Infection In Vivo

Nancy A. Jewell et al.

JOURNAL OF VIROLOGY (2010)

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IFN-γ produced by CD8 T cells induces T-bet-dependent and -independent class switching in B cells in responses to alum-precipitated protein vaccine

Elodie Mohr et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)

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Article Microbiology

Influenza A Virus NS1 Targets the Ubiquitin Ligase TRIM25 to Evade Recognition by the Host Viral RNA Sensor RIG-I

Michaela Ulrike Gack et al.

CELL HOST & MICROBE (2009)

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Review Immunology

The roles of TLRs, RLRs and NLRs in pathogen recognition

Taro Kawai et al.

INTERNATIONAL IMMUNOLOGY (2009)

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Article Immunology

Neonatal Innate TLR-Mediated Responses Are Distinct from Those of Adults

Tobias R. Kollmann et al.

JOURNAL OF IMMUNOLOGY (2009)

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Article Virology

Human Respiratory Syncytial Virus Nonstructural Protein NS2 Antagonizes the Activation of Beta Interferon Transcription by Interacting with RIG-I

Zhenhua Ling et al.

JOURNAL OF VIROLOGY (2009)

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Article Immunology

Activation of innate immune antiviral responses by Nod2

Ahmed Sabbah et al.

NATURE IMMUNOLOGY (2009)

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Review Immunology

Neonatal immunity: faulty T-helpers and the shortcomings of dendritic cells

Habib Zaghouani et al.

TRENDS IN IMMUNOLOGY (2009)

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Respiratory Syncytial Virus Proteins Modulate Suppressors of Cytokine Signaling 1 and 3 and the Type I Interferon Response to Infection by a Toll-Like Receptor Pathway

Christine M. Oshansky et al.

VIRAL IMMUNOLOGY (2009)

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Review Biochemistry & Molecular Biology

Plasmacytoid dendritic cells and type I IFN: 50 years of convergent history

Patricia Fitzgerald-Bocarsly et al.

CYTOKINE & GROWTH FACTOR REVIEWS (2008)

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Interferon regulatory factor 7-mediated responses are defective in cord blood plasmacytoid dendritic cells

Benedicte Danis et al.

EUROPEAN JOURNAL OF IMMUNOLOGY (2008)

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Article Immunology

Delayed maturation of an IL-12-producing dendritic cell subset explains the early Th2 bias in neonatal immunity

Hyun-Hee Lee et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2008)

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Article Immunology

Inchoate CD8(+) T cell responses in neonatal mice permit influenza-induced persistent pulmonary dysfunction

Dahui You et al.

JOURNAL OF IMMUNOLOGY (2008)

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Article Immunology

The biology of influenza viruses

Nicole M. Bouvier et al.

VACCINE (2008)

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Article Immunology

Type I interferon regulates respiratory virus infected dendritic cell maturation and cytokine production

Brian D. Rudd et al.

VIRAL IMMUNOLOGY (2007)

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Article Immunology

Disregulated influenza A virus-specific CD8+ T cell homeostasis in the absence of IFN-γ signaling

Stephen J. Turner et al.

JOURNAL OF IMMUNOLOGY (2007)

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Article Hematology

Interferon regulatory factor 3-dependent responses to lipopolysaccharide are selectively blunted in cord blood cells

Ezra Aksoy et al.

BLOOD (2007)

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Article Immunology

Cutting edge: Influenza A virus activates TLR3-dependent inflammatory and RIG-1-dependent antiviral responses in human lung epithelial cells

Ronan Le Goffic et al.

JOURNAL OF IMMUNOLOGY (2007)

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Article Immunology

Murine neonatal CD4+ cells are poised for rapid Th2 effector-like function

Shawn Rose et al.

JOURNAL OF IMMUNOLOGY (2007)

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Article Virology

Lethal infection of K18-hACE2 mice infected with severe acute respiratory syndrome coronavirus

Paul B. McCray et al.

JOURNAL OF VIROLOGY (2007)

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Article Biochemistry & Molecular Biology

Interferon-inducible Mx gene expression in cotton rats: Cloning, characterization, and expression during influenza viral infection

Lioubov M. Pletneva et al.

JOURNAL OF INTERFERON AND CYTOKINE RESEARCH (2006)

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Article Oncology

Characterization of the mouse IFN-λ ligand-receptor system:: IFN-λs exhibit antitumor activity against B16 melanoma

A Lasfar et al.

CANCER RESEARCH (2006)

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Article Virology

Respiratory syncytial virus nonstructural proteins NS1 and NS2 mediate inhibition of Stat2 expression and alpha/beta interferon responsiveness

MS Lo et al.

JOURNAL OF VIROLOGY (2005)

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Review Immunology

Mechanisms of type-I- and type-II-interferon-mediated signalling

LC Platanias

NATURE REVIEWS IMMUNOLOGY (2005)

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Suppression of the induction of alpha, beta, and gamma interferons by the NS1 and NS2 proteins of human respiratory syncytial virus in human epithelial cells and macrophages

KM Spann et al.

JOURNAL OF VIROLOGY (2004)

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Article Immunology

IL-4 utilizes an alternative receptor to drive apoptosis of Th2 cells and skews neonatal immunity toward Th2

LQ Li et al.

IMMUNITY (2004)

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Article Virology

A recombinant influenza A virus expressing an RNA-binding-defective NS1 protein induces high levels of beta interferon and is attenuated in mice

NR Donelan et al.

JOURNAL OF VIROLOGY (2003)

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Article Immunology

Peripheral CD4+ lymphocytes derived from fetal versus adult thymic precursors differ phenotypically and functionally

B Adkins

JOURNAL OF IMMUNOLOGY (2003)

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Article Multidisciplinary Sciences

T-bet is required for optimal production of IFN-γ and antigen-specific T cell activation by dendritic cells

G Lugo-Villarino et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)

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Article Multidisciplinary Sciences

Critical role for STAT4 activation by type 1 interferons in the interferon-γ response to viral infection

KB Nguyen et al.

SCIENCE (2002)

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Article Multidisciplinary Sciences

Distinct effects of T-bet in TH1 lineage commitment and IFN-γ production in CD4 and CD8 T cells

SJ Szabo et al.

SCIENCE (2002)

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Article Immunology

CX3C chemokine mimicry by respiratory syncytial virus G glycoprotein

RA Tripp et al.

NATURE IMMUNOLOGY (2001)

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Review Pediatrics

Impaired interferon gamma-mediated immunity and susceptibility to mycobacterial infection in childhood

N Remus et al.

PEDIATRIC RESEARCH (2001)

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Article Immunology

Pattern recognition receptors TLR4 and CD14 mediate response to respiratory syncytial virus

EA Kurt-Jones et al.

NATURE IMMUNOLOGY (2000)

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