Related references
Note: Only part of the references are listed.Urolithin A ameliorates obesity-induced metabolic cardiomyopathy in mice via mitophagy activation
Jian-rong Huang et al.
ACTA PHARMACOLOGICA SINICA (2023)
Ellagitannins, urolithins, and neuroprotection: Human evidence and the possible link to the gut microbiota
Rocio Garcia-Villalba et al.
MOLECULAR ASPECTS OF MEDICINE (2023)
Urolithin A reduces amyloid-beta load and improves cognitive deficits uncorrelated with plaque burden in a mouse model of Alzheimer's disease
Josue Ballesteros-Alvarez et al.
GEROSCIENCE (2023)
Effect of urolithin A on the improvement of vascular endothelial function depends on the gut microbiota
Yuichiro Nishimoto et al.
FRONTIERS IN NUTRITION (2023)
Parkinson's Disease: Exploring Different Animal Model Systems
Engila Khan et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2023)
Assessment of heterogeneity among participants in the Parkinson's Progression Markers Initiative cohort using α-synuclein seed amplification: a cross-sectional study
Andrew Siderowf et al.
LANCET NEUROLOGY (2023)
Physiologically-Based Pharmacokinetic Modeling of the Postbiotic Supplement Urolithin A Predicts its Bioavailability Is Orders of Magnitude Lower than Concentrations that Induce Toxicity, but also Neuroprotective Effects
Georg Aichinger et al.
MOLECULAR NUTRITION & FOOD RESEARCH (2023)
Urolithin A (UA) attenuates ferroptosis in LPS-induced acute lung injury in mice by upregulating Keap1-Nrf2/HO-1 signaling pathway
Lejing Lou et al.
FRONTIERS IN PHARMACOLOGY (2023)
Natural Coumarin Derivatives Activating Nrf2 Signaling Pathway as Lead Compounds for the Design and Synthesis of Intestinal Anti-Inflammatory Drugs
Luiz C. Di Stasi
PHARMACEUTICALS (2023)
The effect of a high-polyphenol Mediterranean diet (Green-MED) combined with physical activity on age-related brain atrophy: the Dietary Intervention Randomized Controlled Trial Polyphenols Unprocessed Study (DIRECT PLUS)
Alon Kaplan et al.
AMERICAN JOURNAL OF CLINICAL NUTRITION (2022)
Neurodegenerative disorders management: state-of-art and prospects of nano-biotechnology
Raj Kumar et al.
CRITICAL REVIEWS IN BIOTECHNOLOGY (2022)
Urolithins: a Comprehensive Update on their Metabolism, Bioactivity, and Associated Gut Microbiota
Rocio Garcia-Villalba et al.
MOLECULAR NUTRITION & FOOD RESEARCH (2022)
Urolithin A alleviates blood-brain barrier disruption and attenuates neuronal apoptosis following traumatic brain injury in mice
Qiu-Yuan Gong et al.
NEURAL REGENERATION RESEARCH (2022)
Ellagitannins, promising pharmacological agents for the treatment of cancer stem cells
Zohre Senobari et al.
PHYTOTHERAPY RESEARCH (2022)
Urolithin A protects dopaminergic neurons in experimental models of Parkinson's disease by promoting mitochondrial biogenesis through the SIRT1/PGC-1α signaling pathway
Jia Liu et al.
FOOD & FUNCTION (2022)
Effect of Urolithin A Supplementation on Muscle Endurance and Mitochondrial Health in Older Adults A Randomized Clinical Trial
Sophia Liu et al.
JAMA NETWORK OPEN (2022)
Direct supplementation with Urolithin A overcomes limitations of dietary exposure and gut microbiome variability in healthy adults to achieve consistent levels across the population
Anurag Singh et al.
EUROPEAN JOURNAL OF CLINICAL NUTRITION (2022)
Urolithin A promotes mitophagy and suppresses NLRP3 inflammasome activation in lipopolysaccharide-induced BV2 microglial cells and MPTP-induced Parkinson's disease model
Jingru Qiu et al.
NEUROPHARMACOLOGY (2022)
Monogenic Parkinson's Disease: Genotype, Phenotype, Pathophysiology, and Genetic Testing
Fangzhi Jia et al.
GENES (2022)
UROLITHIN A: GUT-BRAIN DIETARY INTERVENTION IN PARKINSON'S DISEASE
Jenny Hong Yu Ng et al.
Innovation in Aging (2022)
Expansion of T memory stem cells with superior anti-tumor immunity by Urolithin A-induced mitophagy
Dominic Denk et al.
IMMUNITY (2022)
Pharmacotherapeutic potential of pomegranate in age-related neurological disorders
Mohammad Javad Emami Kazemabad et al.
FRONTIERS IN AGING NEUROSCIENCE (2022)
Cytochrome P450 1A1 is essential for the microbial metabolite, Urolithin A-mediated protection against colitis
Sweta Ghosh et al.
FRONTIERS IN IMMUNOLOGY (2022)
A Combination Therapy of Urolithin A plus EGCG Has Stronger Protective Effects than Single Drug Urolithin A in a Humanized Amyloid Beta Knockin Mice for Late-Onset Alzheimer's Disease
Sudhir Kshirsagar et al.
CELLS (2022)
Urolithin A improves muscle strength, exercise performance, and biomarkers of mitochondrial health in a randomized trial in middle-aged adults
Anurag Singh et al.
CELL REPORTS MEDICINE (2022)
Urolithins: potential biomarkers of gut dysbiosis and disease stage in Parkinson's patients
Maria Romo-Vaquero et al.
FOOD & FUNCTION (2022)
Comparative studies of urolithins and their phase II metabolites on macrophage and neutrophil functions
Aneta Bobowska et al.
EUROPEAN JOURNAL OF NUTRITION (2021)
Distribution of Urolithins Metabotypes in Healthy Chinese Youth: Difference in Gut Microbiota and Predicted Metabolic Pathways
Wenyan Xian et al.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2021)
Urolithin A induces cell cycle arrest and apoptosis by inhibiting Bcl-2, increasing p53-p21 proteins and reactive oxygen species production in colorectal cancer cells
Mohammad S. El-Wetidy et al.
CELL STRESS & CHAPERONES (2021)
Neuroprotective Potential of Ellagic Acid: A Critical Review
Ashutosh Gupta et al.
ADVANCES IN NUTRITION (2021)
The Punicalagin Metabolites Ellagic Acid and Urolithin A Exert Different Strengthening and Anti-Inflammatory Effects on Tight Junction-Mediated Intestinal Barrier Function In Vitro
Nina A. Hering et al.
FRONTIERS IN PHARMACOLOGY (2021)
Urolithin A ameliorates experimental autoimmune encephalomyelitis by targeting aryl hydrocarbon receptor
Pei-Xin Shen et al.
EBIOMEDICINE (2021)
Therapeutic Potential of Mitophagy-Inducing Microflora Metabolite, Urolithin A for Alzheimer's Disease
Dona Pamoda W. Jayatunga et al.
NUTRIENTS (2021)
Ecocatalysed Hurtley reaction: Synthesis of urolithin derivatives as new potential RAGE antagonists with anti-ageing properties
Tho Guerin et al.
SUSTAINABLE CHEMISTRY AND PHARMACY (2021)
Urolithin A improves muscle function by inducing mitophagy in muscular dystrophy
Peiling Luan et al.
SCIENCE TRANSLATIONAL MEDICINE (2021)
Urolithin A Inhibits Epithelial-Mesenchymal Transition in Lung Cancer Cells via P53-Mdm2-Snail Pathway
Feng Cheng et al.
ONCOTARGETS AND THERAPY (2021)
Impact of the Natural Compound Urolithin A on Health, Disease, and Aging
Davide D'Amico et al.
TRENDS IN MOLECULAR MEDICINE (2021)
Quercetin hinders microglial activation to alleviate neurotoxicity via the interplay between NLRP3 inflammasome and mitophagy
Xiaojuan Han et al.
REDOX BIOLOGY (2021)
Pomegranate Juice Ameliorates Dopamine Release and Behavioral Deficits in a Rat Model of Parkinson's Disease
Malgorzata Kujawska et al.
BRAIN SCIENCES (2021)
Urolithin A induces prostate cancer cell death in p53-dependent and in p53-independent manner
Yasir I. Mohammed Saleem et al.
EUROPEAN JOURNAL OF NUTRITION (2020)
Parkinson Disease Epidemiology, Pathology, Genetics, and Pathophysiology
David K. Simon et al.
CLINICS IN GERIATRIC MEDICINE (2020)
Neuroprotective Effects of Pomegranate Juice against Parkinson's Disease and Presence of Ellagitannins-Derived Metabolite-Urolithin A-In the Brain
Malgorzata Kujawska et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)
Diagnosis and Treatment of Parkinson Disease A Review
Melissa J. Armstrong et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2020)
Pancreas protective effects of Urolithin A on type 2 diabetic mice induced by high fat and streptozotocin via regulating autophagy and AKT/mTOR signaling pathway
Bahetibieke Tuohetaerbaike et al.
JOURNAL OF ETHNOPHARMACOLOGY (2020)
Autonomic dysfunction in Parkinson's disease: Implications for pathophysiology, diagnosis, and treatment
Zhichun Chen et al.
NEUROBIOLOGY OF DISEASE (2020)
The Metabolite Urolithin-A Ameliorates Oxidative Stress in Neuro-2a Cells, Becoming a Potential Neuroprotective Agent
Guillermo Casedas et al.
ANTIOXIDANTS (2020)
The gut microbiota metabolite urolithin A, but not other relevant urolithins, induces p53-dependent cellular senescence in human colon cancer cells
Juan Antonio Gimenez-Bastida et al.
FOOD AND CHEMICAL TOXICOLOGY (2020)
Urolithin A exerts antiobesity effects through enhancing adipose tissue thermogenesis in mice
Bo Xia et al.
PLOS BIOLOGY (2020)
Where to Look into the Puzzle of Polyphenols and Health? The Postbiotics and Gut Microbiota Associated with Human Metabotypes
Adrian Cortes-Martin et al.
MOLECULAR NUTRITION & FOOD RESEARCH (2020)
Microbial Metabolite Urolithin B Inhibits Recombinant Human Monoamine Oxidase A Enzyme
Rajbir Singh et al.
METABOLITES (2020)
Ellagic Acid and Its Microbial Metabolite Urolithin A Alleviate Diet-Induced Insulin Resistance in Mice
Jieping Yang et al.
MOLECULAR NUTRITION & FOOD RESEARCH (2020)
Ellagic Acid-Derived Urolithins as Modulators of Oxidative Stress
Jasmina Djedjibegovic et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2020)
Potential of the ellagic acid-derived gut microbiota metabolite - Urolithin A in gastrointestinal protection
Malgorzata Kujawska et al.
WORLD JOURNAL OF GASTROENTEROLOGY (2020)
Protective Effects of a Strawberry Ellagitannin-Rich Extract against Pro-Oxidative and Pro-Inflammatory Dysfunctions Induced by a High-Fat Diet in a Rat Model
Ewa Zary-Sikorska et al.
MOLECULES (2020)
Urolithin A augments angiogenic pathways in skeletal muscle by bolstering NAD+ and SIRT1
Nandini Ghosh et al.
SCIENTIFIC REPORTS (2020)
Urolithins in Human Breast Milk after Walnut Intake and Kinetics of Gordonibacter Colonization in Newly Born: The Role of Mothers' Urolithin Metabotypes
Adrian Cortes-Martin et al.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2020)
Urolithin A Prevents Focal Cerebral Ischemic Injury via Attenuating Apoptosis and Neuroinflammation in Mice
Xiao-Hong Lin et al.
NEUROSCIENCE (2020)
Neuroprotective effects of urolithin A on H2O2-induced oxidative stress-mediated apoptosis in SK-N-MC cells
Kkot Byeol Kim et al.
NUTRITION RESEARCH AND PRACTICE (2020)
Pomegranate Fruit and Juice (cv. Mollar), Rich in Ellagitannins and Anthocyanins, Also Provide a Significant Content of a Wide Range of Proanthocyanidins
Huertas M. Diaz-Mula et al.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2019)
Urolithin A attenuates memory impairment and neuroinflammation in APP/PS1 mice
Zhuo Gong et al.
JOURNAL OF NEUROINFLAMMATION (2019)
Dietary Black Raspberries Impact the Colonic Microbiome and Phytochemical Metabolites in Mice
Junnan Gu et al.
MOLECULAR NUTRITION & FOOD RESEARCH (2019)
Mitophagy inhibits amyloid-β and tau pathology and reverses cognitive deficits in models of Alzheimer's disease
Evandro F. Fang et al.
NATURE NEUROSCIENCE (2019)
Urolithin A, a Gut Metabolite, Improves Insulin Sensitivity Through Augmentation of Mitochondrial Function and Biogenesis
Ashley Mulcahy Toney et al.
OBESITY (2019)
Urolithin A-activated autophagy but not mitophagy protects against ischemic neuronal injury by inhibiting ER stress in vitro and in vivo
Anil Ahsan et al.
CNS NEUROSCIENCE & THERAPEUTICS (2019)
Primary Metabolites, Anthocyanins, and Hydrolyzable Tannins in the Pomegranate Fruit
Irit Bar-Ya'akov et al.
FRONTIERS IN PLANT SCIENCE (2019)
Protective effect of urolithin a on cisplatin-induced nephrotoxicity in mice via modulation of inflammation and oxidative stress
Taile Jing et al.
FOOD AND CHEMICAL TOXICOLOGY (2019)
The NLRP3 Inflammasome: An Overview of Mechanisms of Activation and Regulation
Nathan Kelley et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)
Identification of Novel Urolithin Metabolites in Human Feces and Urine after the Intake of a Pomegranate Extract
Rocio Garcia-Villalba et al.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2019)
Urolithin A gains in antiproliferative capacity by reducing the glycolytic potential via the p53/TIGAR axis in colon cancer cells
Elisabeth Norden et al.
CARCINOGENESIS (2019)
Enhancement of the gut barrier integrity by a microbial metabolite through the Nrf2 pathway
Rajbir Singh et al.
NATURE COMMUNICATIONS (2019)
An in silico investigation on the inhibitory potential of the constituents of Pomegranate juice on antioxidant defense mechanism: Relevance to neurodegenerative diseases
Muhammed Khairujjaman Mazumder et al.
IBRO REPORTS (2019)
The mitophagy activator urolithin A is safe and induces a molecular signature of improved mitochondrial and cellular health in humans
Penelope A. Andreux et al.
NATURE METABOLISM (2019)
Oral delivery of nanoparticle urolithin A normalizes cellular stress and improves survival in mouse model of cisplatin-induced AKI
Dianxiong Zou et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2019)
Metabolite of ellagitannins, urolithin A induces autophagy and inhibits metastasis in human sw620 colorectal cancer cells
Wenhua Zhao et al.
MOLECULAR CARCINOGENESIS (2018)
Ellagic acid protects from myelin-associated sphingolipid loss in experimental autoimmune encephalomyelitis
Rebeca Busto et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS (2018)
In Vitro Research on Dietary Polyphenols and Health: A Call of Caution and a Guide on How To Proceed
Maria Angeles Avila-Galvez et al.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2018)
Urolithin A shows anti-atherosclerotic activity via activation of class B scavenger receptor and activation of Nef2 signaling pathway
Guang-Hao Cui et al.
PHARMACOLOGICAL REPORTS (2018)
The gut microbiota urolithin metabotypes revisited: the human metabolism of ellagic acid is mainly determined by aging
A. Cortes-Martin et al.
FOOD & FUNCTION (2018)
Polyphenols in Parkinson's Disease: A Systematic Review of In Vivo Studies
Malgorzata Kujawska et al.
NUTRIENTS (2018)
SIRT1/PGC-1α Signaling Promotes Mitochondrial Functional Recovery and Reduces Apoptosis after Intracerebral Hemorrhage in Rats
Yang Zhou et al.
FRONTIERS IN MOLECULAR NEUROSCIENCE (2018)
A natural molecule, urolithin A, downregulates androgen receptor activation and suppresses growth of prostate cancer
Nisha R. Dahiya et al.
MOLECULAR CARCINOGENESIS (2018)
Mechanisms of mitophagy in cellular homeostasis, physiology and pathology
Konstantinos Palikaras et al.
NATURE CELL BIOLOGY (2018)
What Is the Evidence that Parkinson's Disease Is a Prion Disorder, Which Originates in the Gut?
Malgorzata Kujawska et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)
Inflammasome inhibition prevents α-synuclein pathology and dopaminergic neurodegeneration in mice
Richard Gordon et al.
SCIENCE TRANSLATIONAL MEDICINE (2018)
Neuroprotective Effects of Bioavailable Polyphenol-Derived Metabolites against Oxidative Stress-Induced Cytotoxicity in Human Neuroblastoma SH-SY5Y Cells
Antonio Gonzalez-Sarrias et al.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2017)
Safety assessment of Urolithin A, a metabolite produced by the human gut microbiota upon dietary intake of plant derived ellagitannins and ellagic acid
Jacqueline Heilman et al.
FOOD AND CHEMICAL TOXICOLOGY (2017)
Urolithin A alleviates myocardial ischemia/reperfusion injury via PI3K/Akt pathway
Lu Tang et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2017)
Urolithin A induces mitophagy and prolongs lifespan in C-elegans and increases muscle function in rodents
Dongryeol Ryu et al.
NATURE MEDICINE (2016)
MDS clinical diagnostic criteria for Parkinson's disease
Ronald B. Postuma et al.
MOVEMENT DISORDERS (2015)
Pomegranate ellagitannins inhibit α-glucosidase activity in vitro and reduce starch digestibility under simulated gastro-intestinal conditions
Andrea Bellesia et al.
INTERNATIONAL JOURNAL OF FOOD SCIENCES AND NUTRITION (2015)
Pomegranate phenolics inhibit formation of advanced glycation endproducts by scavenging reactive carbonyl species
Weixi Liu et al.
FOOD & FUNCTION (2014)
Pomegranate Juice Augments Memory and fMRI Activity in Middle-Aged and Older Adults with Mild Memory Complaints
Susan Y. Bookheimer et al.
EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE (2013)
Transgenic expression and activation of PGC-1α protect dopaminergic neurons in the MPTP mouse model of Parkinson's disease
Giuseppa Mudo et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2012)
Acetyl-L-carnitine and alpha-lipoic acid affect rotenone-induced damage in nigral dopaminergic neurons of rat brain, implication for Parkinson's disease therapy
Sawsan A. Zaitone et al.
PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR (2012)
Share Paper
