☆ 4.7 Review

COVID-19 and Male Infertility: Is There a Role for Antioxidants?

ANTIOXIDANTS (2023)

Related references

Note: Only part of the references are listed.

Editorial Material Obstetrics & Gynecology

COVID-19 and hypogonadism: secondary immune responses rule-over endocrine mechanisms

Pallav Sengupta et al.

Summary: Men are more susceptible to SARS-CoV-2 infection and experience reduced testosterone levels. This could be due to direct viral invasion of the testes or the impact of inflammation and oxidative stress on steroid synthesis caused by SARS-CoV-2 infection.

HUMAN FERTILITY (2023)

Add to Collection

Article Public, Environmental & Occupational Health

Effect of COVID-19 infection on sex hormone levels in hospitalized patients: A prospective longitudinal study in Iran

Poorandokht Afshari et al.

Summary: This study aimed to evaluate the levels of sex hormones in patients with COVID-19 in Ahvaz, Iran. The findings showed that the level of estradiol increased significantly in female patients, while the level of testosterone decreased in male patients during the active phase of infection. Further studies are needed to confirm these results.

HEALTH SCIENCE REPORTS (2023)

Add to Collection

Review Urology & Nephrology

SARS-CoV-2 infection (COVID-19) and male fertility: Something we should be worried about?

Theodosia Zeginiadou et al.

Summary: As of 2021, the estimated number of deaths linked to SARS-CoV-2 infection reached around 5 million according to the World Health Organization. The pandemic has had a devastating impact on healthcare systems globally and has raised concerns about its effect on male reproduction. Evidence suggests that COVID-19 adversely affects spermatogenesis and hormonal balance, but more research is needed to understand the long-term impact. Currently, there is no data supporting the negative effect of COVID-19 vaccines on male reproductive health.

UROLOGIA JOURNAL (2023)

Add to Collection

Review Endocrinology & Metabolism

COVID-19 and its treatments: lights and shadows on testicular function

Francesco Pallotti et al.

Summary: COVID-19 may have indirect effects on male reproductive system, but there is limited evidence to support this. Despite the low quality of available evidence, careful andrological evaluation and follow-up for men recovering from COVID-19 are still necessary.

ENDOCRINE (2023)

Add to Collection

Article Andrology

COVID-19 vaccination is associated with a decreased risk of orchitis and/or epididymitis in men

Chase Carto et al.

Summary: The study found that receiving at least 1 COVID-19 vaccine is associated with a decreased risk of developing orchitis and/or epididymitis after balancing for confounding variables.

ANDROLOGIA (2022)

Add to Collection

Article Andrology

Predictors of pregnancy and time to pregnancy in infertile men with idiopathic oligoasthenospermia pre- and post-coenzyme Q10 therapy

Ahmed T. Alahmar et al.

Summary: A 6-month therapy of CoQ10 can improve semen parameters and antioxidant measures, and reduce sperm DNA fragmentation in men with idiopathic oligoasthenospermia. CoQ10 level, male age, semen parameters, ROS and GPx could potentially be used as diagnostic biomarkers for male fertility, as well as predictors for pregnancy outcome and time to pregnancy in these patients.

ANDROLOGIA (2022)

Add to Collection

Review Immunology

Could SARS-CoV-2 infection affect male fertility and sexuality?

Nicola Delli Muti et al.

Summary: This review examines the impact of SARS-CoV-2 infection on the male reproductive system, finding that it not only damages the respiratory system but also has serious effects on male reproduction, including deteriorating semen quality and increasing oxidative stress levels. However, due to a limited number of studies, it remains unclear whether these effects are temporary or long-lasting.

APMIS (2022)

Add to Collection

Editorial Material Urology & Nephrology

Linking COVID-19 vaccine and male infertility - not on fertile ground Comment

Justin La et al.

BJU INTERNATIONAL (2022)

Add to Collection

Review Biology

Why do men have worse COVID-19-related outcomes? A systematic review and meta-analysis with sex adjusted for age

J. Fabiao et al.

Summary: This study aimed to investigate the mechanism behind worse COVID-19 outcomes in men and whether the differences in mortality and severity between sexes are influenced by sex hormones. The findings showed that men had a higher risk of COVID-19 mortality and severity compared to women, regardless of age, suggesting a limited role of sex hormones in these outcomes.

BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH (2022)

Add to Collection

Article Obstetrics & Gynecology

Sperm quality and absence of SARS-CoV-2 RNA in semen after COVID-19 infection: a prospective, observational study and validation of the SpermCOVID test

Gilbert G. G. Donders et al.

Summary: This study aimed to investigate the contagiousness of sperm and its impact on fertility after COVID-19 infection. A prospective cohort study was conducted on Belgian men who had recovered from the infection. The results showed that SARS-CoV-2 RNA was not detected in the semen of the participants. However, a decrease in sperm motility was observed in a significant percentage of men shortly after COVID-19 infection. The study also found that sperm quality might be compromised after COVID-19 infection, but further follow-up studies are needed to confirm the recovery time and the possibility of permanent damage.

FERTILITY AND STERILITY (2022)

Add to Collection

Review Obstetrics & Gynecology

Potential Role of Zinc in the COVID-19 Disease Process and its Probable Impact on Reproduction

Ramya Sethuram et al.

Summary: COVID-19 is a global health crisis with significant impact on morbidity and mortality, and zinc is being trialed as a potential treatment against the disease due to its roles in combating oxidative damage and viral infections. Understanding the pathophysiology of COVID-19, particularly in relation to reproductive function, and the potential effects of zinc depletion on fertility are important areas of research to better mitigate the impact of the virus.

REPRODUCTIVE SCIENCES (2022)

Add to Collection

Editorial Material Urology & Nephrology

Re: The Impact of COVID-19 Vaccine on Sperm Quality

Walter D. Cardona Maya et al.

EUROPEAN UROLOGY (2022)

Add to Collection

Article Obstetrics & Gynecology

The BNT162b2 mRNA Covid-19 vaccine does not impair sperm parameters

Myriam Safrai et al.

Summary: This study investigated the effect of the BNT162b2 COVID-19 vaccine on sperm parameters. By comparing the changes in sperm parameters before and after vaccination, it was found that the vaccine did not significantly affect sperm parameters in patients with a normal or abnormal semen analysis.

REPRODUCTIVE BIOMEDICINE ONLINE (2022)

Add to Collection

Article Urology & Nephrology

Impact of COVID-19 on Male Fertility

Alexander B. Collins et al.

UROLOGY (2022)

Add to Collection

Article Andrology

Prospective two-arm study of the testicular function in patients with COVID-19

Dmitry Enikeev et al.

Summary: This study aimed to investigate the effects of COVID-19 on the male reproductive system. The results showed that COVID-19 significantly affected male hormone levels and sperm quality during the onset of the disease. However, these effects returned to normal within 3 months.

ANDROLOGY (2022)

Add to Collection

Article Andrology

Rapid impact of COVID-19 infection on semen quality: a case report

Parviz Gharagozloo et al.

Summary: A unique opportunity to study the impact of COVID-19 on male reproductive function was presented by analyzing semen quality in a male subject before, during, and after infection. The results showed that a moderate COVID-19 infection led to a temporary state of azoospermia in the subject, which quickly reversed as the infection waned. This suggests that even a moderate case of COVID-19 can have significant effects on male fertility and sperm quality.

TRANSLATIONAL ANDROLOGY AND UROLOGY (2022)

Add to Collection

Article Public, Environmental & Occupational Health

COVID-19 Vaccination Does Not Affect Reproductive Health Parameters in Men

Marco Reschini et al.

Summary: This study examined the impact of COVID-19 vaccination on male reproductive health by assessing semen parameters and fertilization rate before and after vaccination. The results indicate that the vaccine does not affect sperm quality and fertilization capacity of men undergoing ART treatments.

FRONTIERS IN PUBLIC HEALTH (2022)

Add to Collection

Article Andrology

Investigate the effect of COVID-19 inactivated vaccine on sperm parameters and embryo quality in in vitro fertilization

Weiting Xia et al.

Summary: In this study, it was found that the COVID-19 inactivated vaccine had no negative effect on sperm parameters and embryo quality in IVF.

ANDROLOGIA (2022)

Add to Collection

Review Physiology

COVID-19, Oxidative Stress, and Male Reproductive Dysfunctions: Is Vitamin C a Potential Remedy?

Pallav Sengupta et al.

Summary: COVID-19 has a higher prevalence in men due to the higher expression of ACE2 in male reproductive tissues. Recent studies have shown the involvement of oxidative stress and oxidant-sensitive pathways in SARS-CoV-2 infection-mediated male reproductive disruptions. The virus can be found in semen and cause oxidative damage in the testis. Vitamin C, a major testicular antioxidant, has been shown to be effective in treating COVID-19 and protecting against testicular oxidative stress and damage.

PHYSIOLOGICAL RESEARCH (2022)

Add to Collection

Letter Andrology

A suggestion to overcome potential risks for infertility due to COVID-19: A response to Aitken

Loris Marin et al.

ANDROLOGY (2022)

Add to Collection

Letter Andrology

COVID-19 and male infertility: An update

Robert John Aitken

ANDROLOGY (2022)

Add to Collection

Article Andrology

The relationship of serum testosterone levels with the clinical course and prognosis of COVID-19 disease in male patients: A prospective study

Ahmet Emre Cinislioglu et al.

Summary: The study found that lower serum total testosterone levels in male COVID-19 patients were associated with poor prognosis and fatal outcomes, indicating a potential role for testosterone in the pathogenesis of the disease. This could help clinicians determine the clinical course of COVID-19.

ANDROLOGY (2022)

Add to Collection

Article Andrology

Testosterone in males with COVID-19: A 7-month cohort study

Andrea Salonia et al.

Summary: Although total testosterone levels increased over time after COVID-19, more than 50% of men who recovered from the disease still had circulating testosterone levels suggestive for a condition of hypogonadism at 7-month follow-up. In as many as 10% of cases, testosterone levels even further decreased. Of clinical relevance, the higher the burden of comorbid conditions at presentation, the lower the probability of testosterone levels recovery over time.

ANDROLOGY (2022)

Add to Collection

Review Environmental Sciences

Metabolic, Oxidative and Psychological Stress as Mediators of the Effect of COVID-19 on Male Infertility: A Literature Review

Gesthimani Mintziori et al.

Summary: This review assesses the impact of SARS-CoV-2 infection on male fertility, finding that the infection may reduce male fertility by affecting factors such as metabolism, oxidative stress, and psychological stress.

INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH (2022)

Add to Collection

Article Endocrinology & Metabolism

COVID-19 autopsy cases: detection of virus in endocrine tissues

A. M. Poma et al.

Summary: The study found that the SARS-CoV-2 virus can spread to endocrine organs in severe cases of COVID-19, with evidence of virus presence in abdominal subcutaneous adipose tissue, testes, and thyroid samples; Further research is needed to assess the occurrence rate of this phenomenon in clinically mild cases; Potential long-term effects of COVID-19 on endocrine functions should be taken into consideration.

JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION (2022)

Add to Collection

Article Andrology

4BNT162b2 mRNA COVID-19 vaccine and semen: What do we know?

Soraya Olana et al.

Summary: This study found no significant differences in spermatozoa parameters before and after mRNA COVID-19 vaccine inoculations, suggesting that the vaccine is safe for male semen quality.

ANDROLOGY (2022)

Add to Collection

Article Biochemistry & Molecular Biology

COVID-19, Oxidative Stress and Male Reproduction: Possible Role of Antioxidants

Pallav Sengupta et al.

Summary: COVID-19 has a negative impact on male reproductive health, primarily due to systemic inflammatory responses and oxidative stress. Antioxidant therapy may help alleviate male reproductive disruptions caused by SARS-CoV-2 infection.

ANTIOXIDANTS (2022)

Add to Collection

Article Urology & Nephrology

Case series-COVID-19 is unlikely to affect male fertility: Results of histopathological and reverse transcriptase polymerase chain reaction analysis

John M. Masterson et al.

Summary: Our results suggest that SARS-CoV-2 is unlikely to affect male fertility. Contrary to all prior histological studies, our results showed no evidence of damage to reproductive tissues that might impair fertility.

CUAJ-CANADIAN UROLOGICAL ASSOCIATION JOURNAL (2022)

Add to Collection

Review Peripheral Vascular Disease

Preeclampsia and severe acute respiratory syndrome coronavirus 2 infection: a systematic review

Giovanni Tossetta et al.

Summary: This article systematically searched relevant databases to explore the potential link between the SARS-CoV-2 virus and the onset of preeclampsia during pregnancy. Some studies suggest that pregnant women with COVID-19 are more likely to develop preeclampsia compared to those without the virus. However, due to hypertension being a common factor in both conditions, there is currently no specific diagnostic tool to differentiate between the two.

JOURNAL OF HYPERTENSION (2022)

Add to Collection

Review Biochemistry & Molecular Biology

Antioxidant Intervention against Male Infertility: Time to Design Novel Strategies

Cristobal avila et al.

Summary: Infertility is a common condition that affects a significant percentage of couples worldwide, with male infertility being a prominent cause. Oxidative stress has been increasingly recognized as a key factor in male infertility, but effective antioxidant interventions have not yet been established.

BIOMEDICINES (2022)

Add to Collection

Article Andrology

Covid-19 vaccination BNT162b2 temporarily impairs semen concentration and total motile count among semen donors

Itai Gat et al.

Summary: This study investigates the impact of the covid-19 vaccine on semen parameters and finds a temporary decline in sperm concentration and total motile count in the short term, but long-term recovery is expected.

ANDROLOGY (2022)

Add to Collection

Article Andrology

Effects of Covid-19 vaccination on different semen parameters

Ziad H. Abd et al.

Summary: This study suggests that the Pfizer-BioNTech mRNA COVID-19 vaccine has no deleterious effects on semen parameters in terms of male fertility. Although there were statistically significant differences in total sperm motility and progressive motility, these differences are clinically insignificant.

BASIC AND CLINICAL ANDROLOGY (2022)

Add to Collection

Article Andrology

COVID-19 vaccination and male fertility issues: Myth busted. Is taking COVID-19 vaccine the best choice for semen protection and male fertility from risky infection hazards?

Doaa M. Elhabak et al.

Summary: This study investigated the effects of COVID-19 vaccines on semen quality in 100 Egyptian men, and found no significant changes in semen parameters before and after vaccination.

ANDROLOGIA (2022)

Add to Collection

Article Medicine, Research & Experimental

Changes in Spermatogenesis, Lipoperoxidation Processes, and Antioxidant Protection in Men with Pathozoospermia after COVID-19. The Effectiveness of Correction with a Promising Antioxidant Complex

N. A. Kurashova et al.

Summary: This study assessed the effects of an antioxidant complex on spermatogenesis and the prooxidant-antioxidant balance in men with pathozoospermia after recovering from COVID-19. The antioxidant complex improved sperm motility, reduced leukocyte count in the ejaculate, and restored balance in the prooxidant-antioxidant system. It shows promise in reducing oxidative stress and improving spermatogenesis parameters.

BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE (2022)

Add to Collection

Article Biochemistry & Molecular Biology

Oxidative Stress Markers and Sperm DNA Fragmentation in Men Recovered from COVID-19

Anastasiia D. Shcherbitskaia et al.

Summary: SARS-CoV-2 infection has a negative impact on semen characteristics and impairs various biochemical processes, leading to male fertility decline. This study investigates the role of oxidative stress in the consequences of coronavirus infection and suggests that the decline in semen quality and increase in DNA fragmentation after COVID-19 may be caused by an imbalance in semen pro- and antioxidant components.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2022)

Add to Collection

Article Genetics & Heredity

Sperm quality is not affected by the BNT162b2 mRNA SARS-CoV-2 vaccine: results of a 6-14 months follow-up

Gilad Karavani et al.

Summary: The findings of this study suggest that the Pfizer-BioNTech (BNT162b2) SARS-CoV-2 vaccine does not have a significant impact on sperm quality over a relatively long period of 6 to 14 months post-vaccination. There were no differences in semen volume, sperm concentration, motility, morphology, and total motile count between pre- and post-vaccination samples across the entire study cohort and in subgroups of men who received a third dose or had pre-vaccination normal or abnormal sperm. Additionally, there was no correlation between the time from vaccination and post-vaccination sperm parameters.

JOURNAL OF ASSISTED REPRODUCTION AND GENETICS (2022)

Add to Collection

Review Urology & Nephrology

Semen parameters and sex hormones as affected by SARS-CoV-2 infection: A systematic review

J. Bao et al.

Summary: The study systematically reviewed data on semen parameters and sex hormones in COVID-19 patients, finding that infected patients exhibit differences compared to controls but these tend to normalize as they recover.

PROGRES EN UROLOGIE (2022)

Add to Collection

Article Andrology

Investigating Impacts of CoronaVac Vaccination in Males on In Vitro Fertilization: A Propensity Score Matched Cohort Study

Meng Wang et al.

Summary: This study aimed to evaluate the effects of SARS-CoV-2 vaccination on male fertility and found that the vaccination did not have significant impact on gamete and embryo development as well as in vitro fertilization outcomes. Male participants after vaccination showed fluctuating semen parameters but remained within normal limits.

WORLD JOURNAL OF MENS HEALTH (2022)

Add to Collection

Article Reproductive Biology

Semen characteristics of individuals before and after Covishield™ vaccination

Huidrom Yaiphaba Meitei et al.

Summary: This study aimed to understand the impact of Covishield (TM) vaccine on ejaculate quality. The results showed no significant variation in semen characteristics between the follow-up samples and the baseline samples. The study confirmed that Covishield (TM) vaccine does not have a detrimental effect on male fertility.

REPRODUCTION AND FERTILITY (2022)

Add to Collection

Review Reproductive Biology

N-acetyl cysteine as a potential regulator of SARS-CoV-2-induced male reproductive disruptions

Pallav Sengupta et al.

Summary: This article explains the mechanisms of how NAC treatment for COVID-19 may prevent the infection-mediated disruptions in male reproduction.

MIDDLE EAST FERTILITY SOCIETY JOURNAL (2022)

Add to Collection

Article Obstetrics & Gynecology

The impact of COVID-19 vaccine on sperm quality

Shimi Barda et al.

Summary: This study aimed to investigate the effect of the Pfizer BNT162b SARS-CoV-2 vaccine on sperm quality. The results showed that there was an increase in total sperm count and total motile count after receiving the second vaccine, while the percentage of motile sperm did not change.

INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS (2022)

Add to Collection

Review Public, Environmental & Occupational Health

Viral Infections and Male Infertility: A Comprehensive Review of the Role of Oxidative Stress

Roland E. Akhigbe et al.

Summary: Viral infections pose a threat to male fertility by inducing inflammatory responses, oxidative stress, and testicular damage. Antioxidant therapy may be beneficial in protecting against the risk of male infertility.

FRONTIERS IN REPRODUCTIVE HEALTH (2022)

Add to Collection

Article Andrology

Evaluation of inactivated COVID-19 vaccine on semen parameters in reproductive-age males: a retrospective cohort study

Hong Zhu et al.

Summary: This study found no significant changes in male fertility after receiving the COVID-19 vaccine, providing important information for guiding fertility recommendations for assisted reproductive technology patients and donors.

ASIAN JOURNAL OF ANDROLOGY (2022)

Add to Collection

Review Pharmacology & Pharmacy

Administration of Antioxidants in the Infertile Male: When it may have a Beneficial Effect?

Zsolt Kopa et al.

Summary: Antioxidant supplementation may protect sperms against oxidative stress, but excessive exposure can lead to reductive stress, affecting sperm function and embryo development. Studies on antioxidant treatment in male infertility reported improvements in sperm parameters, but also highlighted the uncertainties and biases in the results. There is a need for further research on the balance between oxidant and antioxidant systems to better understand their impact on fertility and potential health risks.

CURRENT PHARMACEUTICAL DESIGN (2021)

Add to Collection

Review Pharmacology & Pharmacy

Therapeutic Effects of Micronutrient Supplements on Sperm Parameters: Fact or Fiction?

Fotios Dimitriadis et al.

Summary: The study investigates the effect of micronutrient supplementation on sperm quality, with an inconclusive international literature on the topic. However, some micronutrients show beneficial effects on sperm parameters, potentially aiding infertile patients. Further randomized, controlled trials are needed to determine the efficacy and safety of micronutrient supplements.

CURRENT PHARMACEUTICAL DESIGN (2021)

Add to Collection

Article Andrology

SARS-CoV-2, testosterone and frailty in males (PROTEGGIMI): A multidimensional research project

Andrea Salonia et al.

Summary: Males with SARS-CoV-2 infection are more susceptible to severe complications and have a higher fatality rate. Differences in hormonal milieu may play a significant role in this phenomenon, necessitating further research.

ANDROLOGY (2021)

Add to Collection

Article Andrology

Low testosterone levels predict clinical adverse outcomes in SARS-CoV-2 pneumonia patients

Giulia Rastrelli et al.

Summary: In male patients with SARS-CoV-2 pneumonia, lower testosterone levels are associated with poor prognosis and mortality, indicating a potential role for testosterone in determining clinical outcomes in COVID-19 patients.

ANDROLOGY (2021)

Add to Collection

Letter Critical Care Medicine

The Minimal Effect of Zinc on the Survival of Hospitalized Patients With COVID-19 An Observational Study

Jasper Seth Yao et al.

CHEST (2021)

Add to Collection

Article Andrology

Absence of SARS-CoV-2 in semen of a COVID-19 patient cohort

Liqiang Guo et al.

Summary: In this study, no SARS-CoV-2 RNA was detected in semen samples from patients with recent infection or recovering from COVID-19, indicating the unlikely possibility of viral transmission through semen about 1 month after initial detection.

ANDROLOGY (2021)

Add to Collection

Review Endocrinology & Metabolism

Addressing male sexual and reproductive health in the wake of COVID-19 outbreak

A. Sansone et al.

Summary: The COVID-19 pandemic poses a significant challenge to healthcare systems globally, with severe complications such as micro-thrombosis and DIC. Survivors of COVID-19 may face long-term consequences, including the development of erectile dysfunction, adding to the burden of the disease.

JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION (2021)

Add to Collection

Article Virology

Evaluation of sex-related hormones and semen characteristics in reproductive-aged male COVID-19 patients

Ling Ma et al.

Summary: The study found that although the COVID-19 virus was not detected in the semen of male patients, there were abnormal levels of sex hormones in the COVID-19 group, with a negative correlation with white blood cell counts and C-reactive protein levels.

JOURNAL OF MEDICAL VIROLOGY (2021)

Add to Collection

Letter Medical Laboratory Technology

Testicular Changes Associated With Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)

Abdallah Flaifel et al.

ARCHIVES OF PATHOLOGY & LABORATORY MEDICINE (2021)

Add to Collection

Editorial Material Obstetrics & Gynecology

SARS-CoV-2 and Male Infertility: Possible Multifaceted Pathology

Sulagna Dutta et al.

Summary: COVID-19 may have an impact on male reproductive functions, with the androgen milieu, ACE2 receptor, and inflammatory responses potentially causing testicular dysfunction.

REPRODUCTIVE SCIENCES (2021)

Add to Collection

Article Public, Environmental & Occupational Health

Comparison of 3-and 6-Month Outcomes of Combined Oral L-Carnitine Fumarate and Acetyl-L-Carnitine Therapy, Included in an Antioxidant Formulation, in Patients with Idiopathic Infertility

Marek Szymanski et al.

Summary: Male factor accounts for 35-40% of infertility cases, with idiopathic male infertility often associated with oxidative stress. The use of antioxidative formulation can significantly improve male reproductive disorders.

AMERICAN JOURNAL OF MENS HEALTH (2021)

Add to Collection

Review Urology & Nephrology

Vitamins as primary or adjunctive treatment in infertile men with varicocele: A systematic review

Georgios Tsampoukas et al.

Summary: Vitamins are often used as part of antioxidant treatment for infertile men with varicocele, showing positive impact on semen parameters. However, the effect on pregnancy rates needs further research.

ARAB JOURNAL OF UROLOGY (2021)

Add to Collection

Article Obstetrics & Gynecology

Coenzyme Q10, oxidative stress markers, and sperm DNA damage in men with idiopathic oligoasthenoteratospermia

Ahmed T. Alahmar et al.

Summary: The study found that daily oral administration of 200 mg CoQ10 for 3 months significantly improved sperm quality and antioxidant status in infertile patients with idiopathic OAT, while reducing ROS and SDF levels.

CLINICAL AND EXPERIMENTAL REPRODUCTIVE MEDICINE-CERM (2021)

Add to Collection

Review Andrology

The role of N-acetyl-cysteine (NAC) orally daily on the sperm parameters and serum hormones in idiopathic infertile men: A systematic review and meta-analysis of randomised controlled trials

Zhongbao Zhou et al.

Summary: Oral daily intake of NAC significantly improves sperm parameters in idiopathic infertile men, but does not have a significant impact on serum hormones, requiring more high-quality studies to confirm.

ANDROLOGIA (2021)

Add to Collection

Article Andrology

Investigation of SARS-CoV-2 in semen samples and the effects of COVID-19 on male sexual health by using semen analysis and serum male hormone profile: A cross-sectional, pilot study

Mustafa Zafer Temiz et al.

Summary: This study investigated the potential presence of SARS-CoV-2 in male semen samples of COVID-19 patients and compared semen parameters and hormone levels before and after treatment. The results showed that there was no viral presence in the semen samples, but significant differences were observed in sperm morphology and serum hormone levels among the groups. Overall, COVID-19 and its treatment did not have a specific deteriorative effect on male sexual health in the short term, although abnormalities in physiological indicators were noted.

ANDROLOGIA (2021)

Add to Collection

Letter Immunology

Pathological and molecular examinations of postmortem testis biopsies reveal SARS-CoV-2 infection in the testis and spermatogenesis damage in COVID-19 patients

Xixiang Ma et al.

CELLULAR & MOLECULAR IMMUNOLOGY (2021)

Add to Collection

Review Biochemistry & Molecular Biology

T Lymphocytes and Testicular Immunity: A New Insight into Immune Regulation in Testes

Jialei Gong et al.

Summary: The immune privilege of the testes is crucial for normal spermatogenesis, but infection and inflammation can lead to male infertility. Different T cell subsets in the testes may play roles in maintaining immune tolerance and pathogenic immune responses in infection and inflammation.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

Add to Collection

Review Obstetrics & Gynecology

Testicular Atrophy and Hypothalamic Pathology in COVID-19: Possibility of the Incidence of Male Infertility and HPG Axis Abnormalities

Kaviya Selvaraj et al.

Summary: The COVID-19 virus may lead to testicular infections and pathology, causing testicular and hypothalamic pathology which could result in infertility issues. While evidence for such pathologies is currently limited, further investigations and research are necessary to understand the implications fully.

REPRODUCTIVE SCIENCES (2021)

Add to Collection

Article Andrology

No detection of SARS-CoV-2 from urine, expressed prostatic secretions, and semen in 74 recovered COVID-19 male patients: A perspective and urogenital evaluation

Yajun Ruan et al.

Summary: This study investigated the urogenital involvement in recovered male COVID-19 patients and found no direct urogenital involvement, but a slight decline in semen quality. Hormonal profiles remained normal. Patients with longer recovery time had lower total sperm count. Further research and follow-up on reproductive function are recommended in the following months.

ANDROLOGY (2021)

Add to Collection

Article Medicine, General & Internal

ACE2 Expression in Kidney and Testis May Cause Kidney and Testis Infection in COVID-19 Patients

Caibin Fan et al.

Summary: The study found that ACE2 is highly expressed in the kidneys and testes, and that SARS-Cov-2 can bind to ACE2 on the surface of cells in these organs, potentially leading to infection. It is recommended to evaluate renal function and provide special care in clinical work, as well as pay attention to the risk of testicular lesions in hospitalized patients and during follow-up, especially in terms of fertility in young patients.

FRONTIERS IN MEDICINE (2021)

Add to Collection

Review Pharmacology & Pharmacy

Administration of Antioxidants in Infertile Male: When it may have a Detrimental Effect?

Fotios Dimitriadis et al.

Summary: Although antioxidants have emerged as a promising solution for male infertility induced by oxidative stress, the excessive use of these compounds may be harmful. Further elaborate studies are needed in the future to explore the effects of antioxidants on semen parameters and fertility potential.

CURRENT PHARMACEUTICAL DESIGN (2021)

Add to Collection

Article Obstetrics & Gynecology

Semen impairment and occurrence of SARS-CoV-2 virus in semen after recovery from COVID-19

M. Gacci et al.

Summary: A prospective study on 43 sexually active men who recovered from SARS-CoV2 revealed that 25% of the men had oligo-crypto-azoospermia. Pathological levels of interleukin-8 (IL-8) in semen were found in 76.7% of the patients. Findings suggest a significant relationship between oligo-crypto-azoospermia and the severity of COVID-19.

HUMAN REPRODUCTION (2021)

Add to Collection

Article Genetics & Heredity

A cohort study of men infected with COVID-19 for presence of SARS-CoV-2 virus in their semen

Corey A. Burke et al.

Summary: A study on 18 men with COVID-19 found no presence of SARS-CoV-2 in their semen samples. This suggests that the virus is not present in semen during the acute or convalescent phase of the disease, consistent with prior findings.

JOURNAL OF ASSISTED REPRODUCTION AND GENETICS (2021)

Add to Collection

Article Urology & Nephrology

SARS-CoV-2 Pneumonia Affects Male Reproductive Hormone Levels: A Prospective, Cohort Study

Mustafa Kadihasanoglu et al.

Summary: This study compared male reproductive hormone levels between patients with COVID-19, non-COVID-19 respiratory tract infection cases, and controls, finding that COVID-19 is associated with decreased TT levels and increased LH and prolactin levels. More severe COVID-19 leads to greater reduction in TT levels and prolonged hospitalization.

JOURNAL OF SEXUAL MEDICINE (2021)

Add to Collection

Article Multidisciplinary Sciences

Evaluation of SARS-CoV-2 in semen, seminal plasma, and spermatozoa pellet of COVID-19 patients in the acute stage of infection

Lucie Delaroche et al.

Summary: The presence of SARS-CoV-2 in semen during the acute phase of the disease is rare, possibly due to contamination during collection.

PLOS ONE (2021)

Add to Collection

Editorial Material Medicine, General & Internal

Post-COVID-19-associated decline in long-term male fertility and embryo quality during assisted reproductive technology

S. Mannur et al.

Summary: COVID-19 can impair male fertility, clinicians should regularly assess patients' reproductive health and men undergoing assisted reproductive technology should be tested for COVID-19 before procedures.

QJM-AN INTERNATIONAL JOURNAL OF MEDICINE (2021)

Add to Collection

Article Developmental Biology

COVID-19 and male reproductive function: a prospective, longitudinal cohort study

Behzad Hajizadeh Maleki et al.

Summary: The study suggests that COVID-19 infection can negatively impact the male reproductive system, leading to changes in seminal biomarkers and significant impairments in sperm quality. These effects may persist over time and be associated with serious reproductive problems.

REPRODUCTION (2021)

Add to Collection

Review Biochemistry & Molecular Biology

Redox Balance in Male Infertility: Excellence through Moderation-Mετρον αριστον

Evangelos N. Symeonidis et al.

Summary: Male infertility is a common medical condition affecting approximately 15% of couples globally, with an estimated 190 million people struggling with it. Urologists face a wide range of male infertility conditions, from typical cases to more complex ones, with oxidative stress being a critical component entailing an imbalance between ROS and antioxidants. The antioxidant paradox poses one of the biggest challenges in andrology, with the emergence of new tools like the MiOXSYS (R) assay offering a quantification of OS and potential solutions for maintaining redox balance.

ANTIOXIDANTS (2021)

Add to Collection

Article Urology & Nephrology

Testosterone's Role in COVID-19

Jeremy M. Auerbach et al.

Summary: COVID-19 consistently shows higher mortality in males, with sex hormones like testosterone playing a role in modulating the immune response. Understanding these epidemiological findings can lead to a more effective response to the disease.

JOURNAL OF SEXUAL MEDICINE (2021)

Add to Collection

Article Endocrinology & Metabolism

Does mRNA SARS-CoV-2 vaccine influence patients' performance during IVF-ET cycle?

Raoul Orvieto et al.

Summary: This observational study aimed to assess the influence of mRNA SARS-CoV-2 vaccine on IVF treatments, and found that the vaccine did not affect ovarian stimulation and embryological variables in patients undergoing IVF cycles immediately after vaccination. Larger studies with longer follow-up are needed to validate these observations.

REPRODUCTIVE BIOLOGY AND ENDOCRINOLOGY (2021)

Add to Collection

Article Andrology

Short-term effects of COVID-19 on semen parameters: A multicenter study of 69 cases

Guven Erbay et al.

Summary: This study investigated the short-term effects of COVID-19 on spermatogenesis and found that it negatively affects sperm parameters, especially in the moderate symptomatic group where a significant decrease in all semen parameters was observed.

ANDROLOGY (2021)

Add to Collection

Article Urology & Nephrology

The effect of N-acetyl cysteine consumption on men with abnormal sperm parameters due to positive history of COVID-19 in the last three months

Bahare Rafiee et al.

Summary: Male infertility accounts for 40-50% of infertility cases and COVID-19 may have negative effects on male fertility. NAC supplementation can improve sperm quality in men with impaired semen analysis due to COVID-19 infection.

ARCHIVIO ITALIANO DI UROLOGIA E ANDROLOGIA (2021)

Add to Collection

Article Andrology

Impaired semen parameters in patients with confirmed SARS-CoV-2 infection: A prospective cohort study

Yasar Pazir et al.

Summary: In this prospective study, researchers found that SARS-CoV-2 infection had a significant impact on semen parameters in men who had recently recovered from mild COVID-19, especially leading to a decrease in sperm motility and total motile sperm count.

ANDROLOGIA (2021)

Add to Collection

Article Andrology

The presence of SARS-CoV-2 virus in semen samples of patients with COVID-19 pneumonia

Baris Saylam et al.

Summary: Some COVID-19 patients may have detectable SARS-CoV-2 in their urine and semen samples, with those with severe clinical conditions and high viral load more likely to test positive in urogenital fluids.

ANDROLOGIA (2021)

Add to Collection

Review Andrology

Absence of SARS-CoV-2 infection in the semen of men recovering from COVID-19 infection: An exploratory study and review of literature

Aditya Prakash Sharma et al.

Summary: The study investigated the presence of SARS-CoV-2 in semen samples of men recovering from COVID-19 and found that the virus was not detected in any of the samples. The systematic literature review also supported the conclusion that SARS-CoV-2 is not found in the semen of patients recovering from COVID-19.

ANDROLOGIA (2021)

Add to Collection

Article Biochemistry & Molecular Biology

COVID-19 disrupts spermatogenesis through the oxidative stress pathway following induction of apoptosis

Negin Moghimi et al.

Summary: Evaluation of apoptosis within the testes of COVID-19 deceased patients revealed significant structural and cellular changes, leading to impaired spermatogenesis. Oxidative stress pathway may be involved in inducing apoptosis in COVID-19 infection.

APOPTOSIS (2021)

Add to Collection

Review Urology & Nephrology

European Association of Urology Guidelines on Male Sexual and Reproductive Health: 2021 Update on Male Infertility

Suks Minhas et al.

Summary: The latest guidelines from the European Association of Urology recommend comprehensive urological evaluation for infertile men to identify and treat modifiable causes of infertility, as well as to monitor their risk for cardiovascular disease and cancer. However, there is still insufficient evidence to support the routine use of some treatments and surgical interventions in clinical practice.

EUROPEAN UROLOGY (2021)

Add to Collection

Article Infectious Diseases

Role of testosterone in SARS-CoV-2 infection: A key pathogenic factor and a biomarker for severe pneumonia

Marta Camici et al.

Summary: The study found that male patients with severe COVID-19 had significantly lower testosterone levels compared to those with mild COVID-19. Low testosterone levels were correlated with hyperinflammatory syndrome and longer hospital stays.

INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES (2021)

Add to Collection

Letter Medicine, General & Internal

Sperm Parameters Before and After COVID-19 mRNA Vaccination

Daniel C. Gonzalez et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2021)

Add to Collection

Article Genetics & Heredity

The relationship of plasma antioxidant levels to semen parameters: the Males, Antioxidants, and Infertility (MOXI) randomized clinical trial

Jennifer F. Knudtson et al.

Summary: In the USA, among men attending fertility centers with sufficient plasma antioxidant levels of zinc, selenium, or vitamin E, no association was observed between vitamins and semen parameters or clinical outcomes in couples with male infertility. Higher levels of antioxidants among men with circulating antioxidants in the normal range do not appear to confer benefit on semen parameters or male fertility.

JOURNAL OF ASSISTED REPRODUCTION AND GENETICS (2021)

Add to Collection

Article Endocrinology & Metabolism

The effects of Vitamin D3 supplementation on Spermatogram and endocrine factors in asthenozoospermia infertile men: a randomized, triple blind, placebo-controlled clinical trial

Leila Maghsoumi-Norouzabad et al.

Summary: Vitamin D3 supplementation had no significant effects on body weight, BMI, WC, BF, serum OCN, LH, FSH, T, E2, SHBG, PRO, T/E2 ratio, FAI, semen volume, sperm count, and normal sperm morphology in infertile men with asthenozoospermia. However, it increased serum 25(OH)VD3, PTH, and phosphorus levels, as well as seminal and serum calcium concentrations, T/LH ratio, total and progressive sperm motility, while significantly decreasing compared to baseline and placebo group.

REPRODUCTIVE BIOLOGY AND ENDOCRINOLOGY (2021)

Add to Collection

Review Biochemistry & Molecular Biology

Coenzyme Q10 and Male Infertility: A Systematic Review

Gianmaria Salvio et al.

Summary: Infertility affects 15% of couples worldwide, with male factor being involved in 50% of cases. Research shows a strong association between oxidative stress and poor seminal fluid quality in male infertility, making antioxidants, such as CoQ10, an important part of treatment. Studies have shown beneficial effects of CoQ10 supplementation on semen parameters, but further research is needed to determine the optimal dosage and combination with other antioxidants.

ANTIOXIDANTS (2021)

Add to Collection

Review Biochemistry & Molecular Biology

The Effect of Antioxidant Supplementation on Operated or Non-Operated Varicocele-Associated Infertility: A Systematic Review and Meta-Analysis

Nikolaos Pyrgidis et al.

Summary: This study reviewed 14 studies and found that antioxidant supplementation did not significantly improve fertility and semen parameters in patients with varicocele-associated infertility, with contradictory results reported. Most included studies raised methodological concerns, leading to the inability to draw definitive conclusions about the efficacy of antioxidant supplementation in this setting, highlighting the need for further research in the field.

ANTIOXIDANTS (2021)

Add to Collection

Article Public, Environmental & Occupational Health

A Meta-Analysis of the Efficacy of L-Carnitine/L-Acetyl-Carnitine or N-Acetyl-Cysteine in Men With Idiopathic Asthenozoospermia

Guangzhu Wei et al.

Summary: The meta-analysis showed that L-carnitine/L-acetyl-carnitine (LC/LAC) and N-acetyl-cysteine (NAC) significantly improved sperm motility and normal morphology in men with idiopathic asthenozoospermia. NAC had a greater effect on sperm concentration and ejaculate volume, while no significant impact on serum hormones was observed.

AMERICAN JOURNAL OF MENS HEALTH (2021)

Add to Collection

Article Developmental Biology

Effects of moderate COVID-19 infection on semen oxidative status and parameters 14 and 120 days after diagnosis

Fatemeh Mohanazadeh Falahieh et al.

Summary: The study shows that the deleterious effects of COVID-19 on sperm properties caused by oxidative stress decrease up to Day 120 after diagnosis, with improvements in parameters like sperm motility and DNA integrity.

REPRODUCTION FERTILITY AND DEVELOPMENT (2021)

Add to Collection

Article Urology & Nephrology

Does COVID-19 Worsen the Semen Parameters? Early Results of a Tertiary Healthcare Center

Erdem Koc et al.

Summary: COVID-19 may have unfavorable effects on the gonadal functions and semen parameters, leading to a decline in sperm quality and sex hormone levels in infertile men.

UROLOGIA INTERNATIONALIS (2021)

Add to Collection

Letter Obstetrics & Gynecology

Antioxidant trials-the need to test for stress

Robert John Aitken

HUMAN REPRODUCTION OPEN (2021)

Add to Collection

Article Andrology

Evaluation of SARS-CoV-2 in Human Semen and Effect on Total Sperm Number: A Prospective Observational Study

Jordan C. Best et al.

Summary: The study investigated the presence of viral RNA in semen and its impact on semen parameters in men with SARS-CoV-2 infection. The results showed that SARS-CoV-2 infection could lower the total sperm number in ejaculate in the acute setting, but the virus was not detected in semen samples from recovered men. Further evaluation is needed to determine if SARS-CoV-2 can affect long-term spermatogenic function.

WORLD JOURNAL OF MENS HEALTH (2021)

Add to Collection

Review Biochemistry & Molecular Biology

Adverse Events Reported From COVID-19 Vaccine Trials: A Systematic Review

Rimple Jeet Kaur et al.

Summary: This study systematically reviewed the safety data from published COVID-19 vaccine trials, indicating that most reactions were mild to moderate, while a few were severe, and all reactions resolved within 3-4 days. COVID-19 vaccines may be safe, but long-term post-marketing surveillance in high-risk vulnerable populations is needed.

INDIAN JOURNAL OF CLINICAL BIOCHEMISTRY (2021)

Add to Collection

Article Infectious Diseases

Presence of SARS-CoV-2 RNA in Semen-Cohort Study in the United States COVID-19 Positive Patients

Bruno Machado et al.

Summary: Research has shown that even in a small sample, the RNA of SARS-CoV-2 can be detected in human semen, highlighting the need for the scientific community and public health officials to be aware of potential new transmission routes and long-term clinical effects on the population.

INFECTIOUS DISEASE REPORTS (2021)

Add to Collection

Article Obstetrics & Gynecology

The effect of antioxidants on male factor infertility: the Males, Antioxidants, and Infertility (MOXI) randomized clinical trial

Anne Z. Steiner et al.

FERTILITY AND STERILITY (2020)

Add to Collection

Article Medicine, General & Internal

Clinical Characteristics of Coronavirus Disease 2019 in China

W. Guan et al.

NEW ENGLAND JOURNAL OF MEDICINE (2020)

Add to Collection

Article Multidisciplinary Sciences

Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation

Daniel Wrapp et al.

SCIENCE (2020)

Add to Collection

Letter Nutrition & Dietetics

Association between regional selenium status and reported outcome of COVID-19 cases in China

Jinsong Zhang et al.

AMERICAN JOURNAL OF CLINICAL NUTRITION (2020)

Add to Collection

Article Pathology

COVID-19 Autopsies, Oklahoma, USA

Lisa M. Barton et al.

AMERICAN JOURNAL OF CLINICAL PATHOLOGY (2020)

Add to Collection

Review Medicine, Research & Experimental

Oxidative Stress as Key Player in Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) Infection

Livan Delgado-Roche et al.

ARCHIVES OF MEDICAL RESEARCH (2020)

Add to Collection

Letter Reproductive Biology

Absence of 2019 novel coronavirus in semen and testes of COVID-19 patients

Ci Song et al.

BIOLOGY OF REPRODUCTION (2020)

Add to Collection

Article Biochemistry & Molecular Biology

Structure, Function, and Antigenicity of the SARS-CoV-2 Spike Glycoprotein

Alexandra C. Walls et al.

CELL (2020)

Add to Collection

Article Biochemistry & Molecular Biology

SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor

Markus Hoffmann et al.

CELL (2020)

Add to Collection

Article Chemistry, Medicinal

Androgen sensitivity gateway to COVID-19 disease severity

Carlos Gustavo Wambier et al.

DRUG DEVELOPMENT RESEARCH (2020)

Add to Collection

Article Obstetrics & Gynecology

Assessment of SARS-CoV-2 in human semen-a cohort study

Nora Holtmann et al.

FERTILITY AND STERILITY (2020)

Add to Collection

Article Immunology

Detectable 2019-nCoV viral RNA in blood is a strong indicator for the further clinical severity

Weilie Chen et al.

EMERGING MICROBES & INFECTIONS (2020)

Add to Collection

Article Dermatology

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is likely to be androgen mediated

Carlos Gustavo Wambier et al.

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY (2020)

Add to Collection

Editorial Material Medicine, General & Internal

Covid-19: risk factors for severe disease and death

Rachel E. Jordan et al.

BMJ-BRITISH MEDICAL JOURNAL (2020)

Add to Collection

Article Multidisciplinary Sciences

Structure of the SARS-CoV-2 spike receptor-binding domain bound to the ACE2 receptor

Jun Lan et al.

NATURE (2020)

Add to Collection

Article Multidisciplinary Sciences

Structural basis of receptor recognition by SARS-CoV-2

Jian Shang et al.

NATURE (2020)

Add to Collection

Article Public, Environmental & Occupational Health

Gender Differences in Patients With COVID-19: Focus on Severity and Mortality

Jian-Min Jin et al.

FRONTIERS IN PUBLIC HEALTH (2020)

Add to Collection

Letter Public, Environmental & Occupational Health

Does SARS-CoV-2 infection cause sperm DNA fragmentation? Possible link with oxidative stress

Pallav Sengupta et al.

EUROPEAN JOURNAL OF CONTRACEPTION AND REPRODUCTIVE HEALTH CARE (2020)

Add to Collection

Article Obstetrics & Gynecology

No evidence of severe acute respiratory syndrome-coronavirus 2 in semen of males recovering from coronavirus disease 2019

Feng Pan et al.

FERTILITY AND STERILITY (2020)

Add to Collection

Editorial Material Multidisciplinary Sciences

Autopsy of COVID-19 patients in China

Xiu-Wu Bian

NATIONAL SCIENCE REVIEW (2020)

Add to Collection

Article Immunology

No Evidence of SARS-CoV-2 Seminal Shedding Despite SARS-CoV-2 Persistence in the Upper Respiratory Tract

Stephen A. Rawlings et al.

OPEN FORUM INFECTIOUS DISEASES (2020)

Add to Collection

Article Cell Biology

The ACE2 expression in Sertoli cells and germ cells may cause male reproductive disorder after SARS-CoV-2 infection

Qiaoyan Shen et al.

JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2020)

Add to Collection

Letter Medicine, General & Internal

Clinical Characteristics and Results of Semen Tests Among Men With Coronavirus Disease 2019

Diangeng Li et al.

JAMA NETWORK OPEN (2020)

Add to Collection

Article Endocrinology & Metabolism

Effect of serum total testosterone and its relationship with other laboratory parameters on the prognosis of coronavirus disease 2019 (COVID-19) in SARS-CoV-2 infected male patients: a cohort study

Selahittin Cayan et al.

AGING MALE (2020)

Add to Collection

Article Urology & Nephrology

Investigation of SARS-CoV-2 in Semen of Patients in the Acute Stage of COVID-19 Infection

Bircan Kayaaslan et al.

UROLOGIA INTERNATIONALIS (2020)

Add to Collection

Review Nutrition & Dietetics

Early Nutritional Interventions with Zinc, Selenium and Vitamin D for Raising Anti-Viral Resistance Against Progressive COVID-19

Jan Alexander et al.

NUTRIENTS (2020)

Add to Collection

Letter Urology & Nephrology

Italian males recovering from mild COVID-19 show no evidence of SARS-CoV-2 in semen despite prolonged nasopharyngeal swab positivity

Carlo Pavone et al.

INTERNATIONAL JOURNAL OF IMPOTENCE RESEARCH (2020)

Add to Collection

News Item Multidisciplinary Sciences

HOW COVID-19 CAN DAMAGE THE BRAIN

Michael Marshall

NATURE (2020)

Add to Collection

Editorial Material Andrology

The testis in patients with COVID-19: virus reservoir or immunization resource?

Federica Barbagallo et al.

TRANSLATIONAL ANDROLOGY AND UROLOGY (2020)

Add to Collection

Article Urology & Nephrology

Pathological Findings in the Testes of COVID-19 Patients: Clinical Implications

Ming Yang et al.

EUROPEAN UROLOGY FOCUS (2020)

Add to Collection

Review Physiology

Coronavirus Disease-19 Infection: Implications on Male Fertility and Reproduction

Annalisa Navarra et al.

FRONTIERS IN PHYSIOLOGY (2020)

Add to Collection

Article Medicine, General & Internal

Impaired spermatogenesis in COVID-19 patients

Honggang Li et al.

ECLINICALMEDICINE (2020)

Add to Collection

Article Reproductive Biology

L-carnitine and L-acetylcarnitine supplementation for idiopathic male infertility

Shen Chuen Khaw et al.

REPRODUCTION AND FERTILITY (2020)

Add to Collection

Review Endocrinology & Metabolism

The relationship between circulating testosterone and inflammatory cytokines in men

Nur-Vaizura Mohamad et al.

AGING MALE (2019)

Add to Collection

Article Andrology

The excessive use of antioxidant therapy: A possible cause of male infertility?

Ralf Henkel et al.

ANDROLOGIA (2019)

Add to Collection

Article Endocrinology & Metabolism

Effects of N-acetyl-cysteine supplementation on sperm quality, chromatin integrity and level of oxidative stress in infertile men

Rahil Jannatifar et al.

REPRODUCTIVE BIOLOGY AND ENDOCRINOLOGY (2019)

Add to Collection

Article Andrology

Effect of metabolic and antioxidant supplementation on sperm parameters in oligo-astheno-teratozoospermia, with and without varicocele: A double-blind placebo-controlled study

G. M. Busetto et al.

ANDROLOGIA (2018)

Add to Collection

Article Urology & Nephrology

Oxidation-reduction potential and sperm DNA fragmentation, and their associations with sperm morphological anomalies amongst fertile and infertile men

Ahmad Majzoub et al.

ARAB JOURNAL OF UROLOGY (2018)

Add to Collection

Review Urology & Nephrology

Role of reactive oxygen species in male infertility: An updated review of literature

Hillary Wagner et al.

ARAB JOURNAL OF UROLOGY (2018)

Add to Collection

Review Obstetrics & Gynecology

Proteomics, oxidative stress and male infertility

Ashok Agarwal et al.

REPRODUCTIVE BIOMEDICINE ONLINE (2014)

Add to Collection

Article Andrology

Human sperm motility and lipid peroxidation in different ascorbic acid concentrations: an in vitro analysis

A. Verma et al.

ANDROLOGIA (2010)

Add to Collection

Article Obstetrics & Gynecology

Coenzyme Q10 treatment in infertile men with idiopathic asthenozoospermia: a placebo-controlled, double-blind randomized trial

Giancarlo Balercia et al.

FERTILITY AND STERILITY (2009)

Add to Collection

Article Obstetrics & Gynecology

Antioxidants to reduce sperm DNA fragmentation:: an unexpected adverse effect

Yves J. R. Menezo et al.

REPRODUCTIVE BIOMEDICINE ONLINE (2007)

Add to Collection

Article Obstetrics & Gynecology

A randomised control trial examining the effect of an antioxidant (Menevit) on pregnancy outcome during IVF-ICSI treatment

Kelton Tremellen et al.

AUSTRALIAN & NEW ZEALAND JOURNAL OF OBSTETRICS & GYNAECOLOGY (2007)

Add to Collection

Article Reproductive Biology

Orchitis: A complication of severe acute respiratory syndrome (SARS)

J Xu et al.

BIOLOGY OF REPRODUCTION (2006)

Add to Collection

Article Obstetrics & Gynecology

Placebo-controlled double-blind randomized trial on the use of L-carnitine, L-acetylcarnitine, or combined L-carnitine and L-acetylcarnitine in men with idiopathic asthenozoospermia

G Balercia et al.

FERTILITY AND STERILITY (2005)

Add to Collection

Article Andrology

Reduction of the incidence of sperm DNA fragmentation by oral antioxidant treatment

E Greco et al.

JOURNAL OF ANDROLOGY (2005)

Add to Collection

Article Biochemistry & Molecular Biology

The effects of combined conventional treatment, oral antioxidants and essential fatty acids on sperm biology in subfertile men

FH Comhaire et al.

PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS (2000)

Add to Collection

© Peeref 2019-2024. All rights reserved.