Related references
Note: Only part of the references are listed.The Selective NLRP3-inflammasome inhibitor MCC950 Mitigates Post-resuscitation Myocardial Dysfunction and Improves Survival in a Rat Model of Cardiac Arrest and Resuscitation
Guanghui Zheng et al.
CARDIOVASCULAR DRUGS AND THERAPY (2023)
Mitochondrial permeability transition pore-dependent necrosis
Dexter J. Robichaux et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2023)
Pharmacological Inhibition of the NLRP3 Inflammasome: Structure, Molecular Activation, and Inhibitor-NLRP3 Interaction
Qiang Ma
PHARMACOLOGICAL REVIEWS (2023)
The mechanism of NLRP3 inflammasome activation and its pharmacological inhibitors
Xiaoyan Zhan et al.
FRONTIERS IN IMMUNOLOGY (2023)
Relationship between ferroptosis and mitophagy in cardiac ischemia reperfusion injury: a mini-review
Cuihua Liu et al.
PEERJ (2023)
Discovery of a novel 1,3,4-oxadiazol-2-one-based NLRP3 inhibitor as a pharmacological agent to mitigate cardiac and metabolic complications in an experimental model of diet-induced metaflammation
Simone Gastaldi et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2023)
Challenges facing the clinical translation of cardioprotection: 35 years after the discovery of ischemic preconditioning
Claudia Penna et al.
VASCULAR PHARMACOLOGY (2022)
Efficacy of Colchicine in the Treatment of Patients With Coronary Artery Disease: A Mini-Review
JingWen Yong et al.
CLINICAL THERAPEUTICS (2022)
Therapeutic potential of MCC950, a specific inhibitor of NLRP3 inflammasome
Hao Li et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2022)
Clinical Application of Serum microRNAs in Atherosclerotic Coronary Artery Disease
Anna Kablak-Ziembicka et al.
JOURNAL OF CLINICAL MEDICINE (2022)
Targeting the NLRP3 inflammasome in cardiovascular diseases
Stefano Toldo et al.
PHARMACOLOGY & THERAPEUTICS (2022)
The role of mitochondria-associated membranes mediated ROS on NLRP3 inflammasome in cardiovascular diseases
Jiahao Zhao et al.
FRONTIERS IN CARDIOVASCULAR MEDICINE (2022)
RG100204, A Novel Aquaporin-9 Inhibitor, Reduces Septic Cardiomyopathy and Multiple Organ Failure in Murine Sepsis
Shireen Mohammad et al.
FRONTIERS IN IMMUNOLOGY (2022)
Multi-faceted roles of cathepsins in ischemia reperfusion injury (Review)
Jaime Huertas et al.
MOLECULAR MEDICINE REPORTS (2022)
Research Progress on the Role of Pyroptosis in Myocardial Ischemia-Reperfusion Injury
Yang Liu et al.
CELLS (2022)
Crystal Structure of NLRP3 NACHT Domain With an Inhibitor Defines Mechanism of Inflammasome Inhibition
Carien Dekker et al.
JOURNAL OF MOLECULAR BIOLOGY (2021)
NLRP3 inflammasome inhibitor INF39 attenuated NLRP3 assembly in macrophages
Yuhua Shi et al.
INTERNATIONAL IMMUNOPHARMACOLOGY (2021)
NLRP3 Inflammasome Inhibitors in Cardiovascular Diseases
Eleonora Mezzaroma et al.
MOLECULES (2021)
Inhibition of NLRP3 inflammasome by glibenclamide attenuated dopaminergic neurodegeneration and motor deficits in paraquat and maneb-induced mouse Parkinson's disease model
Xiaofei Qiu et al.
TOXICOLOGY LETTERS (2021)
Nuclear Receptors in the Control of the NLRP3 Inflammasome Pathway
Helene Duez et al.
FRONTIERS IN ENDOCRINOLOGY (2021)
IP3R1 regulates Ca2+ transport and pyroptosis through the NLRP3/Caspase-1 pathway in myocardial ischemia/reperfusion injury
Guixi Mo et al.
CELL DEATH DISCOVERY (2021)
Mitochondrial Quality Control in Cardiac-Conditioning Strategies against Ischemia-Reperfusion Injury
Wylly Ramses Garcia-Nino et al.
LIFE-BASEL (2021)
The role and transformative potential of IL-19 in atherosclerosis
Wujun Chen et al.
CYTOKINE & GROWTH FACTOR REVIEWS (2021)
The Role of Pyroptosis in Ischemic and Reperfusion Injury of the Heart
Sergey V. Popov et al.
JOURNAL OF CARDIOVASCULAR PHARMACOLOGY AND THERAPEUTICS (2021)
Mitochondrial regulation of ferroptosis
Boyi Gan
JOURNAL OF CELL BIOLOGY (2021)
Adding a Notch to Cardiovascular Disease Therapeutics: A MicroRNA-Based Approach
Luisa Marracino et al.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2021)
The cGAS-STING pathway as a therapeutic target in inflammatory diseases
Alexiane Decout et al.
NATURE REVIEWS IMMUNOLOGY (2021)
Mitochondrial and mitochondrial-independent pathways of myocardial cell death during ischaemia and reperfusion injury
Sean M. Davidson et al.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2020)
Myocardial ischaemia-reperfusion injury and cardioprotection in perspective
Gerd Heusch
NATURE REVIEWS CARDIOLOGY (2020)
Extracellular vesicles and cardiovascular system: Biomarkers and Cardioprotective Effectors
Saveria Femmino et al.
VASCULAR PHARMACOLOGY (2020)
NLRP3 inflammasome in endothelial dysfunction
Baochen Bai et al.
CELL DEATH & DISEASE (2020)
Pro-inflammatory activation of microglia in the brain of patients with sepsis
T. Zrzavy et al.
NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY (2019)
Recent advances in the mechanisms of NLRP3 inflammasome activation and its inhibitors
Yang Yang et al.
CELL DEATH & DISEASE (2019)
MicroRNA Post-transcriptional Regulation of the NLRP3 Inflammasome in Immunopathologies
Gulcin Tezcan et al.
FRONTIERS IN PHARMACOLOGY (2019)
NLRP3 Inflammasome in Cardioprotective Signaling
Coert J. Zuurbier
JOURNAL OF CARDIOVASCULAR PHARMACOLOGY (2019)
Coronary microvascular obstruction: the new frontier in cardioprotection
Gerd Heusch
BASIC RESEARCH IN CARDIOLOGY (2019)
Purified F-ATP synthase forms a Ca2+-dependent high-conductance channel matching the mitochondrial permeability transition pore
Andrea Urbani et al.
NATURE COMMUNICATIONS (2019)
Innate immunity as a target for acute cardioprotection
Coert J. Zuurbier et al.
CARDIOVASCULAR RESEARCH (2019)
Multitarget Strategies to Reduce Myocardial Ischemia/Reperfusion Injury JACC Review Topic of the Week
Sean M. Davidson et al.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2019)
The role of Ca2+ in acid-sensing ion channel 1a-mediated chondrocyte pyroptosis in rat adjuvant arthritis
Xiaoshan Wu et al.
LABORATORY INVESTIGATION (2019)
Colchicine: an ancient drug with novel applications
B. Dasgeb et al.
BRITISH JOURNAL OF DERMATOLOGY (2018)
Pathogenesis of cardiac ischemia reperfusion injury is associated with CK2α-disturbed mitochondrial homeostasis via suppression of FUNDC1-related mitophagy
Hao Zhou et al.
CELL DEATH AND DIFFERENTIATION (2018)
Metaflammation: Tissue-Specific Alterations of the NLRP3 Inflammasome Platform in Metabolic Syndrome
Raffaella Mastrocola et al.
CURRENT MEDICINAL CHEMISTRY (2018)
OLT1177, a ß-sulfonyl nitrile compound, safe in humans, inhibits the NLRP3 inflammasome and reverses the metabolic cost of inflammation
Carlo Marchetti et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)
Inflammasome, pyroptosis, and cytokines in myocardial ischemia-reperfusion injury
Stefano Toldo et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2018)
Role of NLRP-3 Inflammasome in Hypertension: A Potential Therapeutic Target
Teresa Pasqua et al.
CURRENT PHARMACEUTICAL BIOTECHNOLOGY (2018)
Up-regulation of COX-2 and mPGES-1 by 27-hydroxycholesterol and 4-hydroxynonenal: A crucial role in atherosclerotic plaque instability
Simona Gargiulo et al.
FREE RADICAL BIOLOGY AND MEDICINE (2018)
Oxygen-Sensing Nox4 Generates Genotoxic ROS to Induce Premature Senescence of Nucleus Pulposus Cells through MAPK and NF-κB Pathways
Chencheng Feng et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2017)
Dual inhibition of cathepsin G and chymase reduces myocyte death and improves cardiac remodeling after myocardial ischemia reperfusion injury
Bahman Hooshdaran et al.
BASIC RESEARCH IN CARDIOLOGY (2017)
NLRP3 inflammasome activation during myocardial ischemia reperfusion is cardioprotective
O. Sandanger et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2016)
Interleukin-1 Blockade in Acute Decompensated Heart Failure: A Randomized, Double-Blinded, Placebo-Controlled Pilot Study
Benjamin W. Van Tassell et al.
JOURNAL OF CARDIOVASCULAR PHARMACOLOGY (2016)
NEK7 is an essential mediator of NLRP3 activation downstream of potassium efflux
Yuan He et al.
NATURE (2016)
Pharmacological Inhibition of NLRP3 Inflammasome Attenuates Myocardial Ischemia/Reperfusion Injury by Activation of RISK and Mitochondrial Pathways
Raffaella Mastrocola et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2016)
ROS-Mediated NLRP3 Inflammasome Activation in Brain, Heart, Kidney, and Testis Ischemia/Reperfusion Injury
Letteria Minutoli et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2016)
A Study to Investigate the Efficacy and Safety of an Anti-Interleukin-18 Monoclonal Antibody in the Treatment of Type 2 Diabetes Mellitus
Elizabeth A. McKie et al.
PLOS ONE (2016)
SOD2 and the Mitochondrial UPR: Partners Regulating Cellular Phenotypic Transitions
Chenxia He et al.
TRENDS IN BIOCHEMICAL SCIENCES (2016)
Comparative Safety of Interleukin-1 Blockade With Anakinra in Patients With ST-Segment Elevation Acute Myocardial Infarction (from the VCU-ART and VCU-ART2 Pilot Studies)
Antonio Abbate et al.
AMERICAN JOURNAL OF CARDIOLOGY (2015)
Pyroptotic cell death defends against intracellular pathogens
Ine Jorgensen et al.
IMMUNOLOGICAL REVIEWS (2015)
Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death
Jianjin Shi et al.
NATURE (2015)
A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases
Rebecca C. Coll et al.
NATURE MEDICINE (2015)
The protective role of interleukin-18 binding protein in a murine model of cardiac ischemia/reperfusion injury
Haifeng Gu et al.
TRANSPLANT INTERNATIONAL (2015)
Reactive oxygen species and mitochondria: A nexus of cellular homeostasis
Joe Dan Dunn et al.
REDOX BIOLOGY (2015)
The effect of interleukin-1 receptor antagonist therapy on markers of inflammation in non-ST elevation acute coronary syndromes: the MRC-ILA Heart Study
Allison C. Morton et al.
EUROPEAN HEART JOURNAL (2015)
Mechanisms and Functions of Inflammasomes
Mohamed Lamkanfi et al.
CELL (2014)
Safety, tolerability, pharmacokinetics, and pharmacodynamics of single-dose anti-interleukin-18 mAb GSK1070806 in healthy and obese subjects
Prafull Mistry et al.
INTERNATIONAL JOURNAL OF CLINICAL PHARMACOLOGY AND THERAPEUTICS (2014)
A Novel Pharmacologic Inhibitor of the NLRP3 Inflammasome Limits Myocardial Injury After Ischemia-Reperfusion in the Mouse
Carlo Marchetti et al.
JOURNAL OF CARDIOVASCULAR PHARMACOLOGY (2014)
Electrophilic Warhead-Based Design of Compounds Preventing NLRP3 Inflammasome-Dependent Pyroptosis
Mattia Cocco et al.
JOURNAL OF MEDICINAL CHEMISTRY (2014)
Inflammatory caspases are innate immune receptors for intracellular LPS
Jianjin Shi et al.
NATURE (2014)
Effects of Interleukin-1 Blockade With Anakinra on Adverse Cardiac Remodeling and Heart Failure After Acute Myocardial Infarction [from the Virginia Commonwealth. University-Anakinra Remodeling Trial (2) (VCU-ART2) Pilot Study]
Antonio Abbate et al.
AMERICAN JOURNAL OF CARDIOLOGY (2013)
Mitochondrial Pathways, Permeability Transition Pore, and Redox Signaling in Cardioprotection: Therapeutic Implications
Claudia Penna et al.
ANTIOXIDANTS & REDOX SIGNALING (2013)
Influence of Block of NF-Kappa B Signaling Pathway on Oxidative Stress in the Liver Homogenates
Paulina Kleniewska et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2013)
Triggering of Inflammasome by Aggregated α-Synuclein, an Inflammatory Response in Synucleinopathies
Gaia Codolo et al.
PLOS ONE (2013)
Deletion of the Innate Immune NLRP3 Receptor Abolishes Cardiac Ischemic Preconditioning and Is Associated with Decreased Il-6/STAT3 Signaling
Coert J. Zuurbier et al.
PLOS ONE (2012)
Cardioprotective Pathways During Reperfusion: Focus on Redox Signaling and Other Modalities of Cell Signaling
Pasquale Pagliaro et al.
ANTIOXIDANTS & REDOX SIGNALING (2011)
Colchicine inhibits cationic dye uptake induced by ATP in P2X2 and P2X7 receptor-expressing cells: implications for its therapeutic action
C. Marques-da-Silva et al.
BRITISH JOURNAL OF PHARMACOLOGY (2011)
Cutting Edge: Reactive Oxygen Species Inhibitors Block Priming, but Not Activation, of the NLRP3 Inflammasome
Franz Bauernfeind et al.
JOURNAL OF IMMUNOLOGY (2011)
Tissue Factor Is Induced by Resistin in Human Coronary Artery Endothelial Cells by the NF-kappa B-Dependent Pathway
Paolo Calabro et al.
JOURNAL OF VASCULAR RESEARCH (2011)
Non-canonical inflammasome activation targets caspase-11
Nobuhiko Kayagaki et al.
NATURE (2011)
Ischemia and reperfusion-from mechanism to translation
Holger K. Eltzschig et al.
NATURE MEDICINE (2011)
Interleukin-1 Blockade With Anakinra to Prevent Adverse Cardiac Remodeling After Acute Myocardial Infarction (Virginia Commonwealth University Anakinra Remodeling Trial [VCU-ART] Pilot Study)
Antonio Abbate et al.
AMERICAN JOURNAL OF CARDIOLOGY (2010)
Interleukin-1β modulation using a genetically engineered antibody prevents adverse cardiac remodelling following acute myocardial infarction in the mouse
Antonio Abbate et al.
EUROPEAN JOURNAL OF HEART FAILURE (2010)
BAY 11-7082, a Nuclear Factor-κB Inhibitor, Reduces Inflammation and Apoptosis in a Rat Cardiac Ischemia-Reperfusion Injury Model
Yong Sook Kim et al.
INTERNATIONAL HEART JOURNAL (2010)
Neutralization of Interleukin-18 Ameliorates Ischemia/Reperfusion-induced Myocardial Injury
Kaliyamurthi Venkatachalam et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Glyburide inhibits the Cryopyrin/Nalp3 inflammasome
Mohamed Lamkanfi et al.
JOURNAL OF CELL BIOLOGY (2009)
Cutting Edge: NF-κB Activating Pattern Recognition and Cytokine Receptors License NLRP3 Inflammasome Activation by Regulating NLRP3 Expression
Franz G. Bauernfeind et al.
JOURNAL OF IMMUNOLOGY (2009)
MAM: more than just a housekeeper
Teruo Hayashi et al.
TRENDS IN CELL BIOLOGY (2009)
Reactive oxygen species trigger ischernic and pharmacological postconditioning:: In vivo and in vitro characterization
Yasuo M. Tsutsumi et al.
LIFE SCIENCES (2007)
Gout-associated uric acid crystals activate the NALP3 inflammasome
F Martinon et al.
NATURE (2006)
Post-conditioning induced cardioprotection requires signaling through a redox-sensitive mechanism, mitochondrial ATP-sensitive K+ channel and protein kinase C activation
C Penna et al.
BASIC RESEARCH IN CARDIOLOGY (2006)
Neutrophil cathepsin G promotes detachment-induced cardiomyocyte apoptosis via a protease-activated receptor-independent mechanism
A Sabri et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)