4.7 Review

Association between Impaired Ketogenesis and Metabolic-Associated Fatty Liver Disease

Journal

BIOMOLECULES
Volume 13, Issue 10, Pages -

Publisher

MDPI
DOI: 10.3390/biom13101506

Keywords

ketone; ketogenesis; metabolic-associated fatty liver disease

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This review examines previous studies on the association between ketogenesis and MAFLD, and reviews candidate mechanisms that can explain this association.
Metabolic (dysfunction) associated fatty liver disease (MAFLD) is generally developed with excessive accumulation of lipids in the liver. Ketogenesis is an efficient pathway for the disposal of fatty acids in the liver and its metabolic benefits have been reported. In this review, we examined previous studies on the association between ketogenesis and MAFLD and reviewed the candidate mechanisms that can explain this association.

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