☆ 4.7 Review

Extracellular Matrix Proteomics: The mdx-4cv Mouse Diaphragm as a Surrogate for Studying Myofibrosis in Dystrophinopathy

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Summary: This review article provides an overview of the importance of dystrophin in Duchenne muscular dystrophy and its relationship with calcium and excitation-contraction coupling. Studies have shown significant changes in the concentration and/or function of calcium-regulatory proteins in dystrophin-lacking muscles. The chronic influx of calcium ions through the damaged cell membrane and abnormal intracellular calcium fluxes are major pathobiochemical hallmarks of this disease.

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Summary: Molecular treatments for Duchenne muscular dystrophy, such as exon skipping, have been in clinical practice for over 15 years. Promising clinical trials based on earlier works have shown potential in initiating dystrophin production to slow down disease progression. Some of these treatments have received conditional approval from health authorities, but further data accumulation is still necessary.

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Myofibrillar Lattice Remodeling Is a Structural Cytoskeletal Predictor of Diaphragm Muscle Weakness in a Fibrotic mdx (mdx Cmah-/-) Model

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LIFE-BASEL (2022)

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Review Medicine, Research & Experimental

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P. Mukherjee et al.

Summary: Animal models are crucial in biomedical research as they can mimic human diseases and facilitate drug development, medical device advancements, tissue engineering, and surgical studies. Despite ethical concerns and challenges, animal models enable researchers to carry out experiments that would be impossible in humans.

LABORATORY ANIMAL RESEARCH (2022)

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Review Biochemistry & Molecular Biology

Advances in stable isotope labeling: dynamic labeling for spatial and temporal proteomic analysis

Nicole C. Beller et al.

Summary: The SILAC technique in proteomics uses stable isotope labeling in cell culture to differentiate and quantify unlabeled and labeled cells. The pulsed SILAC technique provides a new quantitative dimension for temporal analysis in proteomics. These innovative techniques have contributed to the development of various SILAC-based temporal and spatial labeling applications.

MOLECULAR OMICS (2022)

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Review Biotechnology & Applied Microbiology

A Decade of Progress in Gene Targeted Therapeutic Strategies in Duchenne Muscular Dystrophy: A Systematic Review

Lam Chung Liang et al.

Summary: Duchenne muscular dystrophy (DMD) is a severe form of muscle dystrophy that currently lacks effective treatment options. Gene therapy has been proposed as a potential solution, but it also faces limitations and challenges.

FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY (2022)

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Article Biology

Mass Spectrometric Profiling of Extraocular Muscle and Proteomic Adaptations in the mdx-4cv Model of Duchenne Muscular Dystrophy

Stephen Gargan et al.

Summary: The study of EOM proteomics in dystrophinopathy revealed abnormal expression levels of contractile proteins and adaptation through metabolic shifts and cellular stress responses.

LIFE-BASEL (2021)

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Article Biochemistry & Molecular Biology

Collagen XII mediated cellular and extracellular mechanisms regulate establishment of tendon structure and function

Yayoi Izu et al.

Summary: Collagen XII plays dual roles in tendon development by influencing fibril packing, fiber assembly and stability, as well as regulating tenocyte organization and intercellular communication. Its deficiency results in altered cell shape, impaired cell-cell communication, and decreased tissue stiffness, indicating its crucial role in tendon structure and function. Additionally, collagen XII specifically affects tenocyte biosynthesis and provides feedback to regulate extracellular collagen I, highlighting its significance in tendon development and maintenance.

MATRIX BIOLOGY (2021)

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Article Clinical Neurology

Clinical and Molecular Spectrum Associated with COL6A3 c.7447A>G p.(Lys2483Glu) Variant: Elucidating its Role in Collagen VI-related Myopathies

Rocio N. Villar-Quiles et al.

Summary: This study identified distinct phenotypical and secretion patterns associated with the COL6A3 missense variant c.7447A>G among 16 patients. Patients with compound heterozygosity for this variant exhibited typical COL6-RM features, while homozygous patients showed variability in clinical and imaging findings.

JOURNAL OF NEUROMUSCULAR DISEASES (2021)

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Article Biochemistry & Molecular Biology

The STRING database in 2021: customizable protein-protein networks, and functional characterization of user-uploaded gene/measurement sets

Damian Szklarczyk et al.

Summary: The STRING database integrates various associations between proteins, including physical interactions and functional associations, by collecting evidence from sources such as literature, databases, computational predictions, and systematic transfers. STRING aims for wide coverage and provides extensive user interface features and querying methods for experimental data.

NUCLEIC ACIDS RESEARCH (2021)

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Review Biochemistry & Molecular Biology

Disrupted Calcium Homeostasis in Duchenne Muscular Dystrophy: A Common Mechanism behind Diverse Consequences

Barbara Zablocka et al.

Summary: Duchenne muscular dystrophy is caused by mutations in the DMD gene, leading to the loss of full-length dystrophin and resulting in muscle degeneration, neuropsychological impairment, and bone deformities. Abnormalities in calcium homeostasis are a common feature of this disease, playing a fundamental role in the various abnormalities associated with DMD.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

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Letter Respiratory System

Non-Invasive Ventilation for Acute Respiratory Failure in Duchenne Muscular Dystrophy Patients

Andrea Vianello et al.

ARCHIVOS DE BRONCONEUMOLOGIA (2021)

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Article Biochemical Research Methods

Simple and Efficient Microsolid-Phase Extraction Tip-Based Sample Preparation Workflow to Enable Sensitive Proteomic Profiling of Limited Samples (200 to 10,000 Cells)

James C. Kostas et al.

Summary: The developed OmSET method is efficient and reproducible for processing limited biological samples, with minimal sample volumes and all processing steps conducted on-membrane in a single microreactor. It has been shown to provide reliable label-free quantitation results for low numbers of human monocytes, with excellent correlations between protein abundances and the amounts of starting material, as well as between sample processing replicates.

JOURNAL OF PROTEOME RESEARCH (2021)

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Review Biochemical Research Methods

Reflections on the HUPO Human Proteome Project, the Flagship Project of the Human Proteome Organization, at 10 Years

Gilbert S. Omenn

Summary: The HUPO Human Proteome Project celebrates its 10th anniversary by achieving the milestone of confident detection of proteins from 90% of predicted protein-coding genes. This global project has influenced data-sharing, quality assurance, and issued stringent guidelines for detecting missing proteins. The project's impact is highlighted in special issues of Nature Communications and Journal of Proteome Research.

MOLECULAR & CELLULAR PROTEOMICS (2021)

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Review Pediatrics

A systematic review of pharmacologic therapies for the cardiomyopathy of Duchenne muscular dystrophy

Jasmine Kipke et al.

Summary: The study found that there is still controversy regarding pharmacologic therapies for the cardiomyopathy of Duchenne muscular dystrophy (DMD), specifically whether ACEI, BB, or their combination can improve left ventricular function or alter the progressive decline of left ventricular function. For symptomatic class IV heart failure patients, initiating therapy with ACEI and BB can lead to temporary improvement in symptoms and left ventricular ejection fraction. Aldosterone antagonists may slow the rate of decline of left ventricular function in young DMD patients.

PEDIATRIC PULMONOLOGY (2021)

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Article Multidisciplinary Sciences

Biomarker-focused multi-drug combination therapy and repurposing trial in mdx mice

Michael Ziemba et al.

Summary: Duchenne muscular dystrophy is caused by dystrophin deficiency, leading to downstream pathophysiological pathways that drive disability. Dystrophin replacement strategies may trigger these pathways, so combination therapies targeting multiple downstream pathways are crucial. Blood biomarkers could be used to assess drug combinations for treating DMD in both mouse models and human studies.

PLOS ONE (2021)

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Article Medicine, General & Internal

Duchenne muscular dystrophy

Dongsheng Duan et al.

Summary: Duchenne muscular dystrophy is a severe muscle-wasting disease caused by mutations in the DMD gene, leading to loss of muscle tissue and function as well as cardiomyopathy. Recent studies have deepened understanding of the disease and led to the development of multidisciplinary care guidelines and various therapeutic approaches.

NATURE REVIEWS DISEASE PRIMERS (2021)

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Article Cell & Tissue Engineering

Mesenchymal stem cells derived from human induced pluripotent stem cells improve the engraftment of myogenic cells by secreting urokinase-type plasminogen activator receptor (uPAR)

Ahmed Elhussieny et al.

Summary: The study demonstrated that induced MSC-like cells (iMSCs) promoted the proliferation and differentiation of human myogenic cells and enhanced their engraftment in a DMD model. iMSCs secreted cytokines that facilitated the migration and engraftment of human myogenic cells, showing potential for improving muscle regeneration in dystrophic conditions.

STEM CELL RESEARCH & THERAPY (2021)

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Review Biochemistry & Molecular Biology

Fibro-adipogenic progenitors in skeletal muscle homeostasis, regeneration and diseases

Thomas Molina et al.

Summary: Skeletal muscle regeneration relies on the coordination between muscle stem cells and fibro-adipogenic progenitors (FAPs), with FAPs playing a crucial role by supporting myogenic activity and exhibiting cellular heterogeneity.

OPEN BIOLOGY (2021)

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Article Cell Biology

Protein profile of fiber types in human skeletal muscle: a single-fiber proteomics study

Marta Murgia et al.

Summary: This study utilized single-fiber proteomics to identify 404 proteins with significant differences among different fiber types, including many specific markers for type 1 or 2X fibers. It also revealed other major patterns of protein distribution and highlighted the selective enrichment of certain proteins in specific fiber types, suggesting potential implications in muscle pathophysiology. Single-fiber proteomics, combined with emerging single-cell proteomics approaches, are crucial for exploring and quantifying muscle cell heterogeneity.

SKELETAL MUSCLE (2021)

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Review Biochemistry & Molecular Biology

Annexins and Membrane Repair Dysfunctions in Muscular Dystrophies

Coralie Croissant et al.

Summary: Muscular dystrophies are genetic disorders characterized by weakening and loss of skeletal muscle mass. ANXA proteins are important for membrane repair in cells, and dysregulation of ANXA expression may impact the clinical severity of muscular dystrophies.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

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Article Biochemistry & Molecular Biology

Periostin Is Required for the Maintenance of Muscle Fibers during Muscle Regeneration

Naoki Ito et al.

Summary: In this study, the protective role of periostin, a matricellular protein, in skeletal muscle regeneration was identified. Periostin-null mice showed decreased muscle weight due to the loss of muscle fibers during repeated muscle regeneration. The decrease in CD31-positive blood vessels during muscle regeneration in periostin-null mice suggests that the decreased nutritional supply may be the cause of muscle fiber loss.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

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Review Genetics & Heredity

Quantitative Proteomics Using Isobaric Labeling: A Practical Guide

Xiulan Chen et al.

Summary: Isobaric labeling technology has become a key tool for comparing protein expression in biological samples, although challenges remain in terms of quantitative accuracy and precision. The different types of isobaric mass tags and advantages and disadvantages of the labeling method are detailed, along with precautions needed at each step of the workflow for reliable quantification results. The broad applications of isobaric labeling technology in biological and clinical studies, with a focus on thermal proteome profiling and proteogenomics, are also discussed.

GENOMICS PROTEOMICS & BIOINFORMATICS (2021)

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Article Pharmacology & Pharmacy

Peptide-Functionalized Dendrimer Nanocarriers for Targeted Microdystrophin Gene Delivery

Jessica Hersh et al.

Summary: In this study, a modified G5 PAMAM dendrimer-DNA complex was developed for targeted delivery to skeletal muscle cells, aiming to treat patients with DMD by improving DNA transfection efficiency.

PHARMACEUTICS (2021)

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Article Biochemistry & Molecular Biology

A Comprehensive Phylogenetic Analysis of the Serpin Superfamily

Matthew A. Spence et al.

Summary: This study used a structural alignment of diverse serpins to generate a comprehensive 6,000-sequence phylogeny, showing extensive diversification of the superfamily into many novel functional clades. Analysis indicated that the hub proteins are ancient and similar due to convergent evolution, rather than horizontal gene transfer as previously speculated. This work clarifies longstanding questions in the evolution of serpins and provides new directions for research in the field of serpin biology.

MOLECULAR BIOLOGY AND EVOLUTION (2021)

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Article Multidisciplinary Sciences

FKRP-dependent glycosylation of fibronectin regulates muscle pathology in muscular dystrophy

A. J. Wood et al.

Summary: Mutations in FKRP cause muscular dystrophies with diverse clinical presentations. In addition to targeting alpha-dystroglycan, FKRP also guides the sialylation of fibronectin, which is essential for collagen recruitment to the muscle basement membrane.

NATURE COMMUNICATIONS (2021)

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Review Biochemistry & Molecular Biology

Extracellular matrix: an important regulator of cell functions and skeletal muscle development

Weiya Zhang et al.

Summary: The extracellular matrix plays a crucial role in tissue development and muscle fiber environment, providing structural support and influencing physiological functions. The review provides an in-depth overview of ECM structure, components, its role in skeletal muscle development, and applications in biomedical engineering.

CELL AND BIOSCIENCE (2021)

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Editorial Material Cell Biology

Murine models of Duchenne muscular dystrophy: is there a best model?

Kristy Swiderski et al.

AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2021)

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Review Endocrinology & Metabolism

Laminins in metabolic tissues

Anna Goddi et al.

Summary: Laminins are extracellular matrix proteins that play a crucial role in metabolic tissues by potentially influencing the development and function of specific metabolic cell types. Further research is needed to explore the therapeutic applications of laminins in the context of metabolic diseases.

METABOLISM-CLINICAL AND EXPERIMENTAL (2021)

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Review Physiology

Complexity of skeletal muscle degeneration: multi-systems pathophysiology and organ crosstalk in dystrophinopathy

Kay Ohlendieck et al.

Summary: Duchenne muscular dystrophy is a progressive muscle wasting disorder with systemic effects on various organs, requiring comprehensive biomarker signatures and novel disease markers for differential diagnosis, prognosis, and therapy monitoring. Current therapeutic approaches to combat muscular dystrophy are also summarised.

PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2021)

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Review Biochemical Research Methods

Animal models for researching approaches to therapy of Duchenne muscular dystrophy

M. I. Zaynitdinova et al.

Summary: When choosing an animal model for DMD research, it is important to consider all goals and objectives, as each animal model has its own advantages and disadvantages. Large animal models are crucial for studying the potential efficacy of treatments for DMD.

TRANSGENIC RESEARCH (2021)

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Article Multidisciplinary Sciences

Efficient precise in vivo base editing in adult dystrophic mice

Li Xu et al.

Summary: Recent advances in base editing have allowed for precise correction of disease-causing mutations, but challenges remain in terms of the size of base editors and their off-target activities, as well as the requirement for a specific protospacer adjacent motif (PAM) nearby the mutation site. This study successfully modified an NG-targeting adenine base editor to overcome these challenges and demonstrated its high efficiency in editing a Duchenne muscular dystrophy (DMD) mutation in adult mice, showing promising results with systemic delivery. The authors' approach shows potential for the treatment of monogenic diseases using base editing techniques, addressing limitations in targeting feasibility and packaging capacity.

NATURE COMMUNICATIONS (2021)

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Article Biochemistry & Molecular Biology

Artificial intelligence for proteomics and biomarker discovery

Matthias Mann et al.

Summary: The rapid growth of biomedical data generation and computational capabilities has led to advancements in utilizing machine learning and deep learning in proteomics for predictive modeling and biomarker discovery. These technologies are essential for improving analytical workflows and integrating multi-omics data, while also raising concerns about model transparency, explainability, and data privacy when deploying MS-based biomarkers in clinical settings.

CELL SYSTEMS (2021)

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Review Biochemical Research Methods

Advances in the proteomic profiling of the matrisome and adhesome

Lukas Krasny et al.

Summary: This review summarizes recent advances in proteomic characterization of the matrisome and adhesome, highlighting the importance of curated databases and discussing the key strengths and limitations of different workflows.

EXPERT REVIEW OF PROTEOMICS (2021)

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Review Biochemistry & Molecular Biology

Proteomes Are of Proteoforms: Embracing the Complexity

Katrina Carbonara et al.

Summary: Proteomes are more complex than genomes or transcriptomes, and their analysis requires considering a wide range of proteoforms. Various analytical methods are currently used to study proteomes, but further improvements and refinements are needed in order to gain a deeper understanding of proteomic complexity.

PROTEOMES (2021)

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Review Biochemistry & Molecular Biology

The Dystrophin Node as Integrator of Cytoskeletal Organization, Lateral Force Transmission, Fiber Stability and Cellular Signaling in Skeletal Muscle

Paul Dowling et al.

Summary: This passage discusses the role of the protein product of the DMD gene, dystrophin, in Duchenne muscular dystrophy, as well as its interaction with other proteins in muscle cells. It also highlights the central role of the dystrophin complex in muscle fibers in integrating cytoskeletal organization and cellular signaling at the muscle periphery.

PROTEOMES (2021)

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Article Cell Biology

Proteomic and cell biological profiling of the renal phenotype of the mdx-4cv mouse model of Duchenne muscular dystrophy

Paul Dowling et al.

EUROPEAN JOURNAL OF CELL BIOLOGY (2020)

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Article Biochemical Research Methods

Sample Preparation by Easy Extraction and Digestion (SPEED) - A Universal, Rapid, and Detergent-free Protocol for Proteomics Based on Acid Extraction

Joerg Doellinger et al.

MOLECULAR & CELLULAR PROTEOMICS (2020)

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Article Biochemistry & Molecular Biology

MatrisomeDB: the ECM-protein knowledge database

Xinhao Shao et al.

NUCLEIC ACIDS RESEARCH (2020)

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Review Biochemical Research Methods

Targeted and Untargeted Proteomics Approaches in Biomarker Development

Constance A. Sobsey et al.

PROTEOMICS (2020)

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Review Cell Biology

Mouse models for muscular dystrophies: an overview

Maaike van Putten et al.

DISEASE MODELS & MECHANISMS (2020)

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Review Cell Biology

Biomarkers for Duchenne muscular dystrophy: myonecrosis, inflammation and oxidative stress

Miranda D. Grounds et al.

DISEASE MODELS & MECHANISMS (2020)

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Article Anatomy & Morphology

Diversity of extracellular matrix morphology in vertebrate skeletal muscle

David A. Sleboda et al.

JOURNAL OF MORPHOLOGY (2020)

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Article Geriatrics & Gerontology

Comparative proteomic analyses of Duchenne muscular dystrophy and Becker muscular dystrophy muscles: changes contributing to preserve muscle function in Becker muscular dystrophy patients

Daniele Capitanio et al.

JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE (2020)

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Review Physiology

The Structure and Role of Intramuscular Connective Tissue in Muscle Function

Peter P. Purslow

FRONTIERS IN PHYSIOLOGY (2020)

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Review Physiology

Skeletal Muscle Extracellular Matrix - What Do We Know About Its Composition, Regulation, and Physiological Roles? A Narrative Review

Robert Csapo et al.

FRONTIERS IN PHYSIOLOGY (2020)

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Review Biochemical Research Methods

Duchenne Muscular Dystrophy: recent advances in protein biomarkers and the clinical application

Cristina Al-Khalili Szigyarto

EXPERT REVIEW OF PROTEOMICS (2020)

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Review Biochemistry & Molecular Biology

The discovery of dystrophin, the protein product of the Duchenne muscular dystrophy gene

Eric P. Hoffman

FEBS JOURNAL (2020)

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Review Biochemistry & Molecular Biology

Tissue-Specific Decellularization Methods: Rationale and Strategies to Achieve Regenerative Compounds

Unai Mendibil et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)

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Article Cell Biology

Annexin-A6 in Membrane Repair of Human Skeletal Muscle Cell: A Role in the Cap Subdomain

Coralie Croissant et al.

CELLS (2020)

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Review Genetics & Heredity

Global epidemiology of Duchenne muscular dystrophy: an updated systematic review and meta-analysis

Salvatore Crisafulli et al.

ORPHANET JOURNAL OF RARE DISEASES (2020)

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Article Biochemical Research Methods

Comparative Analysis of the Extracellular Matrix Proteome across the Myotendinous Junction

Kathryn R. Jacobson et al.

JOURNAL OF PROTEOME RESEARCH (2020)

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Article Biochemical Research Methods

Mutation-independent Proteomic Signatures of Pathological Progression in Murine Models of Duchenne Muscular Dystrophy

Tirsa L. E. van Westering et al.

MOLECULAR & CELLULAR PROTEOMICS (2020)

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Article Critical Care Medicine

Impact of Mechanical Ventilation Methods on the Life Perception of Subjects With Duchenne Muscular Dystrophy: French Cross-Sectional Survey

Ghilas Boussaid et al.

RESPIRATORY CARE (2020)

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Article Multidisciplinary Sciences

A high-stringency blueprint of the human proteome

Subash Adhikari et al.

NATURE COMMUNICATIONS (2020)

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Article Multidisciplinary Sciences

Cellular senescence-mediated exacerbation of Duchenne muscular dystrophy

Hidetoshi Sugihara et al.

SCIENTIFIC REPORTS (2020)

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Article Cell Biology

Annexin A2 Mediates Dysferlin Accumulation and Muscle Cell Membrane Repair

Daniel C. Bittel et al.

CELLS (2020)

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Article Multidisciplinary Sciences

Proteome-wide Changes in the mdx-4cv Spleen due to Pathophysiological Cross Talk with Dystrophin-Deficient Skeletal Muscle

Paul Dowling et al.

ISCIENCE (2020)

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Article Multidisciplinary Sciences

Progressive Proteome Changes in the Myocardium of a Pig Model for Duchenne Muscular Dystrophy

Hathaichanok Tamiyakul et al.

ISCIENCE (2020)

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Article Chemistry, Analytical

Photocleavable Surfactant-Enabled Extracellular Matrix Proteomics

Samantha J. Knott et al.

ANALYTICAL CHEMISTRY (2020)

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Review Biochemistry & Molecular Biology

From Mice to Humans: An Overview of the Potentials and Limitations of Current Transgenic Mouse Models of Major Muscular Dystrophies and Congenital Myopathies

Monika Sztretye et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)

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Review Multidisciplinary Sciences

Fibrosis: from mechanisms to medicines

Neil C. Henderson et al.

NATURE (2020)

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Article Biochemical Research Methods

Protocol for the Bottom-Up Proteomic Analysis of Mouse Spleen

Paul Dowling et al.

STAR PROTOCOLS (2020)

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Article Biochemistry & Molecular Biology

Identification of marker proteins of muscular dystrophy in the urine proteome from themdx-4cvmodel of dystrophinopathy

Stephen Gargan et al.

MOLECULAR OMICS (2020)

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Article Multidisciplinary Sciences

Dataset on the mass spectrometry-based proteomic profiling of the kidney from wild type and the dystrophic mdx-4cv mouse model of X-linked muscular dystrophy

Paul Dowling et al.

DATA IN BRIEF (2020)

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Article Biochemical Research Methods

Proteomic analysis of the sarcolemma-enriched fraction from dystrophic mdx-4cv skeletal muscle

Sandra Murphy et al.

JOURNAL OF PROTEOMICS (2019)

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Article Biochemical Research Methods

Beneficial effects of Coomassie staining on proteomic analysis employing PAGE separation followed with whole-gel slicing, in-gel digestion and quantitative LC-MS/MS

Ya Jin et al.

JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES (2019)

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Article Cell Biology

Proteomic profiling of the mouse diaphragm and refined mass spectrometric analysis of the dystrophic phenotype

Sandra Murphy et al.

JOURNAL OF MUSCLE RESEARCH AND CELL MOTILITY (2019)

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Article Biotechnology & Applied Microbiology

Development of Novel Micro-dystrophins with Enhanced Functionality

Julian N. Ramos et al.

MOLECULAR THERAPY (2019)

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Article Clinical Neurology

Respiratory and upper limb function as outcome measures in ambulant and non-ambulant subjects with Duchenne muscular dystrophy: A prospective multicentre study

V. Ricotti et al.

NEUROMUSCULAR DISORDERS (2019)

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Review Cell Biology

Cysteine Cathepsins and Their Extracellular Roles: Shaping the Microenvironment

Eva Vidak et al.

CELLS (2019)

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Article Biochemical Research Methods

Universal Solid-Phase Protein Preparation (USP3) for Bottom-up and Top-down Proteomics

Laura F. Dagley et al.

JOURNAL OF PROTEOME RESEARCH (2019)

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Article Biochemistry & Molecular Biology

Citrullination of fibronectin alters integrin clustering and focal adhesion stability promoting stromal cell invasion

Victoria L. Stefanelli et al.

MATRIX BIOLOGY (2019)

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Article Biochemical Research Methods

A photocleavable surfactant for top-down proteomics

Kyle A. Brown et al.

NATURE METHODS (2019)

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Review Biochemical Research Methods

Identification and Quantification of Proteoforms by Mass Spectrometry

Leah Schaffer et al.

PROTEOMICS (2019)

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Article Cell Biology

Integrin signaling: linking mechanical stimulation to skeletal muscle hypertrophy

Marni D. Boppart et al.

AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2019)

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Article Clinical Neurology

Imaging respiratory muscle quality and function in Duchenne muscular dystrophy

Alison M. Barnard et al.

JOURNAL OF NEUROLOGY (2019)

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Article Chemistry, Analytical

Filter Aided Sample Preparation - A tutorial

Jacek R. Wisniewski

ANALYTICA CHIMICA ACTA (2019)

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Review Biochemistry & Molecular Biology

Exploring the extracellular matrix in health and disease using proteomics

Isra N. Taha et al.

EXTRACELLULAR MATRIX (2019)

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Review Pathology

Emerging proteomic biomarkers of X-linked muscular dystrophy

Paul Dowling et al.

EXPERT REVIEW OF MOLECULAR DIAGNOSTICS (2019)

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Review Biochemistry & Molecular Biology

Cardiac Pathophysiology and the Future of Cardiac Therapies in Duchenne Muscular Dystrophy

Tatyana A. Meyers et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)

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Article Multidisciplinary Sciences

The impact of decellularization methods on extracellular matrix derived hydrogels

Julia Fernandez-Perez et al.

SCIENTIFIC REPORTS (2019)

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Review Cell Biology

Skeletal muscle fibrosis: an overview

Mohamed A. A. Mahdy

CELL AND TISSUE RESEARCH (2019)

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Article Biochemical Research Methods

Single-pot, solid-phase-enhanced sample preparation for proteomics experiments

Christopher S. Hughes et al.

NATURE PROTOCOLS (2019)

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Article Biochemistry & Molecular Biology

Detection of collagens by multispectral optoacoustic tomography as an imaging biomarker for Duchenne muscular dystrophy

Adrian P. Regensburger et al.

NATURE MEDICINE (2019)

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Review Biochemistry & Molecular Biology

Characterization of Contractile Proteins from Skeletal Muscle Using Gel-Based Top-Down Proteomics

Paul Dowling et al.

PROTEOMES (2019)

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Review Biochemistry & Molecular Biology

Innovating the Concept and Practice of Two-Dimensional Gel Electrophoresis in the Analysis of Proteomes at the Proteoform Level

Xianquan Zhan et al.

PROTEOMES (2019)

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Article Clinical Neurology

Echographic Assessment of Diaphragmatic Function in Duchenne Muscular Dystrophy from Childhood to Adulthood

Abdallah Fayssoil et al.

JOURNAL OF NEUROMUSCULAR DISEASES (2019)

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Article Biochemical Research Methods

Mass spectrometry-based protein analysis to unravel the tissue pathophysiology in Duchenne muscular dystrophy

Stephanie J. Carr et al.

PROTEOMICS CLINICAL APPLICATIONS (2018)

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Article Clinical Neurology

Collagen VI is required for the structural and functional integrity of the neuromuscular junction

Matilde Cescon et al.

ACTA NEUROPATHOLOGICA (2018)

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Article Biochemical Research Methods

Proteomic profiling of large myofibrillar proteins from dried and long-term stored polyacrylamide gels

Sandra Murphy et al.

ANALYTICAL BIOCHEMISTRY (2018)

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Article Biochemical Research Methods

Comparative gel-based proteomic analysis of chemically crosslinked complexes in dystrophic skeletal muscle

Sandra Murphy et al.

ELECTROPHORESIS (2018)

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Review Biochemistry & Molecular Biology

At the Crossroads of Clinical and Preclinical Research for Muscular DystrophyAre We Closer to Effective Treatment for Patients?

Kinga I. Gawlik

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)

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Article Biochemical Research Methods

Surfactant and Chaotropic Agent Assisted Sequential Extraction/On-Pellet Digestion (SCAD) for Enhanced Proteomics

Fengfei Ma et al.

JOURNAL OF PROTEOME RESEARCH (2018)

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Article Biochemical Research Methods

SWATH mass spectrometry as a tool for quantitative profiling of the matrisome

Lukas Krasny et al.

JOURNAL OF PROTEOMICS (2018)

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Article Biochemical Research Methods

Application of targeted mass spectrometry in bottom-up proteomics for systems biology research

Nathan P. Manes et al.

JOURNAL OF PROTEOMICS (2018)

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Article Clinical Neurology

Diagnosis and management of Duchenne muscular dystrophy, part 3: primary care, emergency management, psychosocial care, and transitions of care across the lifespan

David J. Birnkrant et al.

LANCET NEUROLOGY (2018)

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Correction Clinical Neurology

Diagnosis and management of Duchenne muscular dystrophy, part 1: diagnosis, and neuromuscular, rehabilitation, endocrine, and gastrointestinal and nutritional management (vol 17, pg 251, 2018)

J. F. Zimmermann et al.

LANCET NEUROLOGY (2018)

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Review Clinical Neurology

Diagnosis and management of Duchenne muscular dystrophy, part 2: respiratory, cardiac, bone health, and orthopaedic management

David J. Birnkrant et al.

LANCET NEUROLOGY (2018)

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Review Biochemistry & Molecular Biology

Regulation of fibrosis in muscular dystrophy

Lucas R. Smith et al.

MATRIX BIOLOGY (2018)

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Review Clinical Neurology

Imaging the heart to detect cardiomyopathy in Duchenne muscular dystrophy: A review

Lisa C. Power et al.

NEUROMUSCULAR DISORDERS (2018)

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Article Multidisciplinary Sciences

Premyogenic progenitors derived from human pluripotent stem cells expand in floating culture and differentiate into transplantable myogenic progenitors

Fusako Sakai-Takemura et al.

SCIENTIFIC REPORTS (2018)

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Review Clinical Neurology

Clinical management of Duchenne muscular dystrophy: the state of the art

Sonia Messina et al.

NEUROLOGICAL SCIENCES (2018)

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Article Cell Biology

A Myogenic Double-Reporter Human Pluripotent Stem Cell Line Allows Prospective Isolation of Skeletal Muscle Progenitors

Jianbo Wu et al.

CELL REPORTS (2018)

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Article Biochemical Research Methods

Proteomic profiling of liver tissue from the mdx-4cv mouse model of Duchenne muscular dystrophy

Sandra Murphy et al.

CLINICAL PROTEOMICS (2018)

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Article Multidisciplinary Sciences

Subproteomic profiling of sarcolemma from dystrophic mdx-4cv skeletal muscle

Sandra Murphy et al.

DATA IN BRIEF (2018)

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Review Biochemistry & Molecular Biology

Targeting TGF Signaling to Address Fibrosis Using Antisense Oligonucleotides

James T. March et al.

BIOMEDICINES (2018)

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Immunobiology of Inherited Muscular Dystrophies

James G. Tidball et al.

COMPREHENSIVE PHYSIOLOGY (2018)

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Dataset on the comparative proteomic profiling of mouse saliva and serum from wild type versus the dystrophic mdx-4cv mouse model of dystrophinopathy

Sandra Murphy et al.

DATA IN BRIEF (2018)

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Diagnosis and management of Duchenne muscular dystrophy, part 1: diagnosis, and neuromuscular, rehabilitation, endocrine, and gastrointestinal and nutritional management

David J. Birnkrant et al.

LANCET NEUROLOGY (2018)

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Humanizing the mdx mouse model of DMD: the long and the short of it

Nora Yucel et al.

NPJ REGENERATIVE MEDICINE (2018)

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Mapping the human skeletal muscle proteome: progress and potential

Daniele Capitanio et al.

EXPERT REVIEW OF PROTEOMICS (2017)

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Biological functions of fucose in mammals

Michael Schneider et al.

GLYCOBIOLOGY (2017)

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Annexin A2 links poor myofiber repair with inflammation and adipogenic replacement of the injured muscle

Aurelia Defour et al.

HUMAN MOLECULAR GENETICS (2017)

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Proteomic profiling of mdx-4cv serum reveals highly elevated levels of the inflammation-induced plasma marker haptoglobin in muscular dystrophy

Sandra Murphy et al.

INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE (2017)

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Article Agriculture, Multidisciplinary

Proteome Analysis Using Isobaric Tags for Relative and Absolute Analysis Quantitation (iTRAQ) Reveals Alterations in Stress-Induced Dysfunctional Chicken Muscle

Tong Xing et al.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2017)

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Data acquisition workflows in liquid chromatography coupled to high resolution mass spectrometry-based metabolomics: Where do we stand?

Francois Fenaille et al.

JOURNAL OF CHROMATOGRAPHY A (2017)

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Proteomic profiling of the dystrophin complex and membrane fraction from dystrophic mdx muscle reveals decreases in the cytolinker desmoglein and increases in the extracellular matrix stabilizers biglycan and fibronectin

Sandra Murphy et al.

JOURNAL OF MUSCLE RESEARCH AND CELL MOTILITY (2017)

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Evaluation of FASP, SP3, and iST Protocols for Proteomic Sample Preparation in the Low Microgram Range

Malte Sielaff et al.

JOURNAL OF PROTEOME RESEARCH (2017)

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The role of laminins in the organization and function of neuromuscular junctions

Robert S. Rogers et al.

MATRIX BIOLOGY (2017)

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Article Clinical Neurology

A NEW METHOD OF GENOTYPING MDX4CV MICE BY PCR-RFLP ANALYSIS

Elisia D. Tichy et al.

MUSCLE & NERVE (2017)

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Molecular pathogenesis of Duchenne muscular dystrophy-related fibrosis

K. Ohlendieck et al.

PATHOLOGE (2017)

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Fibrosis development in early-onset muscular dystrophies: Mechanisms and translational implications

Antonio L. Serrano et al.

SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY (2017)

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Duchenne and Becker Muscular Dystrophies: A Review of Animal Models, Clinical End Points, and Biomarker Quantification

Kristin Wilson et al.

TOXICOLOGIC PATHOLOGY (2017)

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Muscle-specific CRISPR/Cas9 dystrophin gene editing ameliorates pathophysiology in a mouse model for Duchenne muscular dystrophy

Niclas E. Bengtsson et al.

NATURE COMMUNICATIONS (2017)

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The golden retriever model of Duchenne muscular dystrophy

Joe N. Kornegay

SKELETAL MUSCLE (2017)

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Comprehensive Characterization of Glycosylation and Hydroxylation of Basement Membrane Collagen IV by High-Resolution Mass Spectrometry

Trayambak Basak et al.

JOURNAL OF PROTEOME RESEARCH (2016)

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Pathoproteomic profiling of the skeletal muscle matrisome in dystrophinopathy associated myofibrosis

Ashling Holland et al.

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Impaired primary mouse myotube formation on crosslinked type I collagen films is enhanced by laminin and entactin

S. Grefte et al.

ACTA BIOMATERIALIA (2016)

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Comparative proteomic assessment of matrisome enrichment methodologies

Lukas Krasny et al.

BIOCHEMICAL JOURNAL (2016)

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Proteomic profiling of muscle fibre type shifting in neuromuscular diseases

Paul Dowling et al.

EXPERT REVIEW OF PROTEOMICS (2016)

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An actin-dependent annexin complex mediates plasma membrane repair in muscle

Alexis R. Demonbreun et al.

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Proteomic analysis of dystrophin deficiency and associated changes in the aged mdx-4cv heart model of dystrophinopathy-related cardiomyopathy

Sandra Murphy et al.

JOURNAL OF PROTEOMICS (2016)

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Anti-fibrotic effect of pirfenidone in muscle derived-fibroblasts from Duchenne muscular dystrophy patients

Simona Zanotti et al.

LIFE SCIENCES (2016)

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The extracellular matrix: Tools and insights for the omics era

Alexandra Naba et al.

MATRIX BIOLOGY (2016)

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Increased collagen cross-linking is a signature of dystrophin-deficient muscle

Lucas R. Smith et al.

MUSCLE & NERVE (2016)

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Mass-spectrometric exploration of proteome structure and function

Ruedi Aebersold et al.

NATURE (2016)

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Telomere shortening and metabolic compromise underlie dystrophic cardiomyopathy

Alex Chia Yu Chang et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)

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Quantitative proteome profiling of dystrophic dog skeletal muscle reveals a stabilized muscular architecture and protection against oxidative stress after systemic delivery of MuStem cells

Aurelie Lardenois et al.

PROTEOMICS (2016)

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Anti-inflammatory drugs for Duchenne muscular dystrophy: focus on skeletal muscle-releasing factors

Shouta Miyatake et al.

DRUG DESIGN DEVELOPMENT AND THERAPY (2016)

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Elastase levels and activity are increased in dystrophic muscle and impair myoblast cell survival, proliferation and differentiation

N. Arecco et al.

SCIENTIFIC REPORTS (2016)

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Thrombospondin expression in myofibers stabilizes muscle membranes

Davy Vanhoutte et al.

ELIFE (2016)

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The biochemical and mass spectrometric profiling of the dystrophin complexome from skeletal muscle

Sandra Murphy et al.

COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL (2016)

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Progressive muscle proteome changes in a clinically relevant pig model of Duchenne muscular dystrophy

Thomas Froehlich et al.

SCIENTIFIC REPORTS (2016)

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The Pathogenesis and Therapy of Muscular Dystrophies

Simon Guiraud et al.

ANNUAL REVIEW OF GENOMICS AND HUMAN GENETICS, VOL 16 (2015)

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Extraocular muscle satellite cells are high performance myo-engines retaining efficient regenerative capacity in dystrophin deficiency

Pascal Stuelsatz et al.

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Hanging on for the ride: Adhesion to the extracellular matrix mediates cellular responses in skeletal muscle morphogenesis and disease

Michelle F. Goody et al.

DEVELOPMENTAL BIOLOGY (2015)

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Animal models of Duchenne muscular dystrophy: from basic mechanisms to gene therapy

Joe W. McGreevy et al.

DISEASE MODELS & MECHANISMS (2015)

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The TREAT-NMD DMD Global Database: Analysis of More than 7,000 Duchenne Muscular Dystrophy Mutations

Catherine L. Bladen et al.

HUMAN MUTATION (2015)

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Stable isotope labelling methods in mass spectrometry-based quantitative-proteomics

Osama Chahrour et al.

JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS (2015)

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Quantification of Extracellular Matrix Proteins from a Rat Lung Scaffold to Provide a Molecular Readout for Tissue Engineering

Ryan C. Hill et al.

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Time- and compartment-resolved proteome profiling of the extracellular niche in lung injury and repair

Herbert B. Schiller et al.

MOLECULAR SYSTEMS BIOLOGY (2015)

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Comparative Label-Free Mass Spectrometric Analysis of Mildly versus Severely Affected mdx Mouse Skeletal Muscles Identifies Annexin, Lamin, and Vimentin as Universal Dystrophic Markers

Ashling Holland et al.

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Muscle wasting in disease: molecular mechanisms and promising therapies

Shenhav Cohen et al.

NATURE REVIEWS DRUG DISCOVERY (2015)

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Skeletal Muscle Fibrosis in the mdx/utrn plus /- Mouse Validates Its Suitability as a Murine Model of Duchenne Muscular Dystrophy

Kelly M. Gutpell et al.

PLOS ONE (2015)

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Label-free mass spectrometric analysis of the mdx-4cv diaphragm identifies the matricellular protein periostin as a potential factor involved in dystrophinopathy-related fibrosis

Ashling Holland et al.

PROTEOMICS (2015)

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State of the art of 2D DIGE

Georgia Arentz et al.

PROTEOMICS CLINICAL APPLICATIONS (2015)

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Immune-mediated pathology in Duchenne muscular dystrophy

Amy S. Rosenberg et al.

SCIENCE TRANSLATIONAL MEDICINE (2015)

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Inhibition of muscle fibrosis results in increases in both utrophin levels and the number of revertant myofibers in Duchenne muscular dystrophy

Oshrat Levi et al.

ONCOTARGET (2015)

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Genetic Engineering of Dystroglycan in Animal Models of Muscular Dystrophy

Francesca Sciandra et al.

BIOMED RESEARCH INTERNATIONAL (2015)

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Label-free mass spectrometric analysis reveals complex changes in the brain proteome from the mdx-4cv mouse model of Duchenne muscular dystrophy

Sandra Murphy et al.

CLINICAL PROTEOMICS (2015)

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Duchenne Muscular Dystrophy Gene Therapy in the Canine Model

Dongsheng Duan

HUMAN GENE THERAPY CLINICAL DEVELOPMENT (2015)

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Concurrent Label-Free Mass Spectrometric Analysis of Dystrophin Isoform Dp427 and the Myofibrosis Marker Collagen in Crude Extracts from mdx-4cv Skeletal Muscles

Sandra Murphy et al.

PROTEOMES (2015)

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Periostin is temporally expressed as an extracellular matrix component in skeletal muscle regeneration and differentiation

Cansu Ozdemir et al.

GENE (2014)

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Isobaric Labeling-Based Relative Quantification in Shotgun Proteomics

Navin Rauniyar et al.

JOURNAL OF PROTEOME RESEARCH (2014)

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A draft map of the human proteome

Min-Sik Kim et al.

NATURE (2014)

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Mass-spectrometry-based draft of the human proteome

Mathias Wilhelm et al.

NATURE (2014)

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Minimal, encapsulated proteomic-sample processing applied to copy-number estimation in eukaryotic cells

Nils A. Kulak et al.

NATURE METHODS (2014)

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Extracellular matrix assembly: a multiscale deconstruction

Janna K. Mouw et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2014)

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Fibronectin is a serum biomarker for Duchenne muscular dystrophy

F. Cynthia Martin et al.

PROTEOMICS CLINICAL APPLICATIONS (2014)

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Understanding the Process of Fibrosis in Duchenne Muscular Dystrophy

Yacine Kharraz et al.

BIOMED RESEARCH INTERNATIONAL (2014)

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Proteomic Profiling of the Dystrophin-Deficient mdx Phenocopy of Dystrophinopathy-Associated Cardiomyopathy

Ashling Holland et al.

BIOMED RESEARCH INTERNATIONAL (2014)

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Article Medicine, Research & Experimental

Engraftment potential of dermal fibroblasts following in vivo myogenic conversion in immunocompetent dystrophic skeletal muscle

Lindsey A. Muir et al.

MOLECULAR THERAPY-METHODS & CLINICAL DEVELOPMENT (2014)

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Cellular Mechanisms of Tissue Fibrosis. 4. Structural and functional consequences of skeletal muscle fibrosis

Richard L. Lieber et al.

AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2013)

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Protein Analysis by Shotgun/Bottom-up Proteomics

Yaoyang Zhang et al.

CHEMICAL REVIEWS (2013)

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The Multiple Affinities of α-Dystroglycan

Francesca Sciandra et al.

CURRENT PROTEIN & PEPTIDE SCIENCE (2013)

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Proteomics of the Dystrophin-glycoprotein Complex and Dystrophinopathy

Ashling Holland et al.

CURRENT PROTEIN & PEPTIDE SCIENCE (2013)

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The mdx mouse model as a surrogate for Duchenne muscular dystrophy

Terence A. Partridge

FEBS JOURNAL (2013)

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Identification of Disease Specific Pathways Using in Vivo SILAC Proteomics in Dystrophin Deficient mdx Mouse

Sree Rayavarapu et al.

MOLECULAR & CELLULAR PROTEOMICS (2013)

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Neuropsychological and neurobehavioral functioning in Duchenne muscular dystrophy: A review

Wanda M. Snow et al.

NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS (2013)

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Proteomic profiling of cardiomyopathic tissue from the aged mdx model of Duchenne muscular dystrophy reveals a drastic decrease in laminin, nidogen and annexin

Ashling Holland et al.

PROTEOMICS (2013)

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Article Cell & Tissue Engineering

A New Immuno-, Dystrophin- Deficient Model, the NSG-mdx4Cv Mouse, Provides Evidence for Functional Improvement Following Allogeneic Satellite Cell Transplantation

Robert W. Arpke et al.

STEM CELLS (2013)

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Laminin-211 in skeletal muscle function

Johan Holmberg et al.

CELL ADHESION & MIGRATION (2013)

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Alteration of Cardiac Progenitor Cell Potency in GRMD Dogs

M. Cassano et al.

CELL TRANSPLANTATION (2012)

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Mass spectrometry-based proteomics for systems biology

Eduard Sabido et al.

CURRENT OPINION IN BIOTECHNOLOGY (2012)

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Proteomics reveals drastic increase of extracellular matrix proteins collagen and dermatopontin in the aged mdx diaphragm model of Duchenne muscular dystrophy

Steven Carberry et al.

INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE (2012)

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Article Biochemical Research Methods

The Matrisome: In Silico Definition and In Vivo Characterization by Proteomics of Normal and Tumor Extracellular Matrices

Alexandra Naba et al.

MOLECULAR & CELLULAR PROTEOMICS (2012)

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Article Multidisciplinary Sciences

Deletion of periostin reduces muscular dystrophy and fibrosis in mice by modulating the transforming growth factor-β pathway

Angela Lorts et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)

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Overview of the Matrisome-An Inventory of Extracellular Matrix Constituents and Functions

Richard O. Hynes et al.

COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2012)

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The human protein disulfide isomerase gene family

James J. Galligan et al.

HUMAN GENOMICS (2012)

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mdx5cv Mice Manifest More Severe Muscle Dysfunction and Diaphragm Force Deficits than Do mdx Mice

Nicholas Beastrom et al.

AMERICAN JOURNAL OF PATHOLOGY (2011)

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Role of Extracellular Matrix Proteins and Their Receptors in the Development of the Vertebrate Neuromuscular Junction

Neha Singhal et al.

DEVELOPMENTAL NEUROBIOLOGY (2011)

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Dermatopontin Interacts with Fibronectin, Promotes Fibronectin Fibril Formation, and Enhances Cell Adhesion

Aiko Kato et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2011)

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Article Biochemical Research Methods

Quantitative Proteomic Analysis of Dystrophic Dog Muscle

Laetitia Guevel et al.

JOURNAL OF PROTEOME RESEARCH (2011)

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GENOTYPING mdx, mdx3cv, AND mdx4cv MICE BY PRIMER COMPETITION POLYMERASE CHAIN REACTION

Jin-Hong Shin et al.

MUSCLE & NERVE (2011)

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STRUCTURE AND FUNCTION OF THE SKELETAL MUSCLE EXTRACELLULAR MATRIX

Allison R. Gillies et al.

MUSCLE & NERVE (2011)

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Dystrophin Delivery to Muscles of mdx Mice Using Lentiviral Vectors Leads to Myogenic Progenitor Targeting and Stable Gene Expression

En Kimura et al.

MOLECULAR THERAPY (2010)

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SEQUENCING PROTOCOLS TO GENOTYPE mdx, mdx4cv, AND mdx5cv MICE

Glen B. Banks et al.

MUSCLE & NERVE (2010)

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Proteomics by Mass Spectrometry: Approaches, Advances, and Applications

John R. Yates et al.

Annual Review of Biomedical Engineering (2009)

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By-passing the nonsense mutation in the 4(CV) mouse model of muscular dystrophy by induced exon skipping

Chalermchai Mitrpant et al.

JOURNAL OF GENE MEDICINE (2009)

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Article Clinical Neurology

Endomysial Fibrosis in Duchenne Muscular Dystrophy: A Marker of Poor Outcome Associated With Macrophage Alternative Activation

Isabelle Desguerre et al.

JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2009)

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Article Biochemical Research Methods

Characterization of Human Skeletal Muscle Biopsy Samples Using Shotgun Proteomics

Kenneth C. Parker et al.

JOURNAL OF PROTEOME RESEARCH (2009)

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Combination of FASP and StageTip-Based Fractionation Allows In-Depth Analysis of the Hippocampal Membrane Proteome

Jacek R. Wisniewski et al.

JOURNAL OF PROTEOME RESEARCH (2009)

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Article Biochemical Research Methods

Universal sample preparation method for proteome analysis

Jacek R. Wisniewski et al.

NATURE METHODS (2009)

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Article Biochemistry & Molecular Biology

Cell-lineage regulated myogenesis for dystrophin replacement: a novel therapeutic approach for treatment of muscular dystrophy

En Kimura et al.

HUMAN MOLECULAR GENETICS (2008)

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A synaptic nidogen: Developmental regulation and role of nidogen-2 at the neuromuscular junction

Michael A. Fox et al.

NEURAL DEVELOPMENT (2008)

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Characterization of the human skeletal muscle proteome by one-dimensional gel electrophoresis and HPLC-ESI-MS/MS

Kurt Hojlund et al.

MOLECULAR & CELLULAR PROTEOMICS (2008)

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Analysis and validation of proteomic data generated by tandem mass spectrometry

Alexey I. Nesvizhskii et al.

NATURE METHODS (2007)

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Dystroglycan: a possible mediator for reducing congenital muscular dystrophy?

Francesca Sciandra et al.

TRENDS IN BIOTECHNOLOGY (2007)

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Periostin regulates collagen fibrillogenesis and the biomechanical properties of connective tissues

Russell A. Norris et al.

JOURNAL OF CELLULAR BIOCHEMISTRY (2007)

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Collagen structure of tendon relates to function

Marco Franchi et al.

THESCIENTIFICWORLDJOURNAL (2007)

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Proteome analysis of the dystrophin-deficient MDX diaphragm reveals a drastic increase in the heat shock protein cvHSP

Philip Doran et al.

PROTEOMICS (2006)

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Dermatopontin, a novel player in the biology of the extracellular matrix

Osamu Okamoto et al.

CONNECTIVE TISSUE RESEARCH (2006)

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Article Biochemistry & Molecular Biology

A highly functional mini-dystrophin/GFP fusion gene for cell and gene therapy studies of Duchenne muscular dystrophy

S Li et al.

HUMAN MOLECULAR GENETICS (2006)

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Dissecting the signaling and mechanical functions of the dystrophin-glycoprotein complex

LM Judge et al.

JOURNAL OF CELL SCIENCE (2006)

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Review - Mass spectrometry and protein analysis

B Domon et al.

SCIENCE (2006)

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Dysferlin interacts with Annexins A1 and A2 and mediates sarcolemmal wound-healing

NJ Lennon et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2003)

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Muscular dystrophies involving the dystrophin-glycoprotein complex: an overview of current mouse models

M Durbeej et al.

CURRENT OPINION IN GENETICS & DEVELOPMENT (2002)

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Article Clinical Neurology

DMDmdx3Cv and DMDmdx4Cv dystrophin mutations in mice:: rapid polymerase chain reaction genotyping

SH Pearson-White

NEUROMUSCULAR DISORDERS (2002)

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