Related references
Note: Only part of the references are listed.
Article
Biochemistry & Molecular Biology
Clark D. Russell et al.
Article
Multidisciplinary Sciences
Jiaqi Li et al.
Summary: Patients with underlying medical conditions may have lower anti-SARS-CoV-2 spike IgG antibody levels, and continuous monitoring and potential booster shots may be necessary for patients with hypertension or diabetes.
Review
Public, Environmental & Occupational Health
Silvia Martinelli et al.
Summary: This article systematically reviews the humoral response and outcomes after the administration of the fourth dose of the COVID-19 vaccine in immunocompromised patients. The review found that the fourth dose can increase antibody levels and is particularly important for organ transplant recipients and patients with blood cancers.
FRONTIERS IN PUBLIC HEALTH
(2023)
Article
Public, Environmental & Occupational Health
Alberto Catalano et al.
Summary: This study investigates the association between multimorbidity and the severity of SARS-CoV-2 infection in the Piedmont population. The results suggest that individuals with multimorbidity, especially respiratory diseases, are at a higher risk of worse COVID-19 outcomes. These findings are important for public health interventions and targeted prevention strategies.
JMIR PUBLIC HEALTH AND SURVEILLANCE
(2023)
Article
Multidisciplinary Sciences
Depro Das et al.
Summary: Underlying medical conditions pose challenges for low- and middle-income countries in their preparedness for COVID-19. This study investigates the impact of comorbidities on the antibody response to SARS-CoV2 and suggests the need for adjusted immunization strategies.
Review
Medicine, Research & Experimental
Anamika Gupta et al.
Summary: The novel coronavirus SARS-CoV-2 causes major challenges to the healthcare system, with millions of deaths worldwide and a high mortality rate associated with pre-existing clinical conditions. The presence of cardiometabolic diseases and certain medical factors are strongly linked to poor outcomes in COVID-19 patients, leading to severe complications and death.
CLINICAL AND EXPERIMENTAL MEDICINE
(2023)
Review
Oncology
Andrea Becerril-Gaitan et al.
Summary: Patients with cancer have impaired immune response to COVID-19 vaccination compared with controls, with lower seroconversion rates and higher likelihood of SARS-CoV-2 infection.
EUROPEAN JOURNAL OF CANCER
(2022)
Review
Oncology
Atsushi Sakuraba et al.
Summary: Patients with cancer, especially those with hematologic B-cell malignancies, have a lower serologic response to COVID-19 vaccines. Additional strategies for prophylaxis should be considered for cancer patients.
JOURNAL OF HEMATOLOGY & ONCOLOGY
(2022)
Article
Medicine, General & Internal
Victoria Hall et al.
Summary: This study investigated the duration and effectiveness of immunity among healthcare workers in the United Kingdom. It found that two doses of the BNT162b2 vaccine provided high short-term protection against SARS-CoV-2 infection, but this protection significantly decreased after six months. However, infection-acquired immunity boosted by vaccination remained high, even more than one year after infection.
NEW ENGLAND JOURNAL OF MEDICINE
(2022)
Review
Endocrinology & Metabolism
Nanny Natalia M. Soetedjo et al.
Summary: This study aimed to explore the antibody response and seropositivity among DM patients following COVID-19 vaccination and found that they were lower than in healthy subjects. Therefore, it is important to administer vaccines appropriately to DM patients and consider prioritizing them for vaccine boosters.
DIABETES & METABOLIC SYNDROME-CLINICAL RESEARCH & REVIEWS
(2022)
Letter
Infectious Diseases
Thiago Cerqueira-Silva et al.
LANCET INFECTIOUS DISEASES
(2022)
Article
Immunology
Gatot Soegiarto et al.
Summary: This study analyzed the association between demographic and clinical factors and the effectiveness of the CoronaVac vaccine in healthcare workers. The results showed that age and high blood pressure were significantly correlated with antibody levels, while sex and body mass index had no significant effect on antibody titres.
Article
Oncology
Anna R. Giuliano et al.
Summary: This cohort study found that the mRNA-1273 SARS-CoV-2 vaccine induced variable antibody responses that differed by cancer diagnosis and treatment received. These findings suggest that patients with hematologic cancer and those who are receiving immunosuppressive treatments may need additional vaccination doses.
Article
Virology
Giulia Collatuzzo et al.
Summary: This study analyzed the antibody levels after 9 months of COVID-19 vaccination and identified factors influencing these levels. The results showed that antibody levels were associated with gender, age, time since vaccination, previous infection, number of vaccine doses, and vaccine type. Additionally, the study observed a declining trend in antibody levels over time.
Article
Public, Environmental & Occupational Health
Marti Catala et al.
Summary: This study aims to compare the severity of infections between the omicron and delta variants. The results show a significant decrease in hospital and ICU admissions for the omicron variant compared to the delta variant. Additionally, omicron is associated with a reduction in the risk of hospitalization and ICU admission regardless of age and vaccination status.
FRONTIERS IN PUBLIC HEALTH
(2022)
Review
Public, Environmental & Occupational Health
Ren Peiyao et al.
Summary: This study investigates the immunogenicity and safety of COVID-19 vaccines in patients on dialysis. The results show that vaccination helps dialysis patients achieve an immune efficiency of 87%, but may result in adverse events, although the incidence of severe adverse events is very low.
FRONTIERS IN PUBLIC HEALTH
(2022)
Article
Immunology
Giulia Collatuzzo et al.
Summary: This study analyzed the determinants of anti-SARS-CoV-2 IgG titer at 6 months after 2-dose COVID-19 vaccination in an international cohort of healthcare workers. The results showed that female sex, young age, past infection, two vaccine doses, and mRNA and heterologous vaccination predicted higher antibody levels. These findings provide valuable data for comparison with trends observed with longer follow-ups.
FRONTIERS IN IMMUNOLOGY
(2022)
Article
Immunology
Ron Milo et al.
Summary: The study evaluated the impact of DMTs on immune responses in MS patients receiving SARS-CoV-2 vaccinations, showing that most DMT-treated patients developed humoral and T-cell responses following 2nd and 3rd vaccinations. However, certain therapies may lead to weakened immune responses, highlighting the need for tailored vaccination guidelines.
FRONTIERS IN IMMUNOLOGY
(2022)
Article
Immunology
Gatot Soegiarto et al.
Summary: This study analysed the association between demographic/clinical factors, antibody response, and vaccine effectiveness in healthcare workers vaccinated with inactivated virus. The results showed that hypertension is associated with lower antibody titres and breakthrough infection following COVID-19 vaccination, suggesting that blood pressure control might be important to improve the efficacy of inactivated virus vaccine.
Article
Medicine, General & Internal
Merryn Voysey et al.
Summary: The ChAdOx1 nCoV-19 vaccine has been shown to have an acceptable safety profile and effectiveness against symptomatic COVID-19, with higher efficacy observed in the group that received a low dose followed by a standard dose.
Article
Medicine, General & Internal
S. F. Lumley et al.
Summary: In a longitudinal study of seropositive and seronegative health care workers undergoing asymptomatic and symptomatic SARS-CoV-2 testing, the presence of anti-spike or anti-nucleocapsid IgG antibodies was associated with a substantially reduced risk of SARS-CoV-2 reinfection in the ensuing 6 months.
NEW ENGLAND JOURNAL OF MEDICINE
(2021)
Article
Multidisciplinary Sciences
Kate M. Bubar et al.
Summary: The study found that prioritizing the vaccine for adults aged 20 to 49 can minimize the number of cases, while prioritizing the vaccine for adults over 60 can minimize mortality and years of life lost. Redirecting vaccine doses to seronegative individuals through individual-level serological tests can improve the impact of each dose.
Review
Microbiology
Wern Hann Ng et al.
Summary: Hypertension, obesity, and diabetes mellitus are the most prevalent comorbidities in COVID-19 patients, while chronic kidney disease stands out as the most prominent factor leading to death. However, despite its high prevalence, obesity is not associated with mortality in COVID-19 patients.
Article
Medicine, General & Internal
Eleftheria Vasileiou et al.
Summary: The study in Scotland found that the first doses of the BNT162b2 mRNA and ChAdOx1 vaccines were associated with substantial reductions in the risk of COVID-19 hospital admission, with vaccine effectiveness ranging from 88% to 91% at 28-34 days post-vaccination.
Article
Infectious Diseases
Yogini V. Chudasama et al.
Summary: The study highlighted an association between multiple chronic conditions and severe SARS-CoV-2 infection, with multimorbid patients having a higher risk of severe infection compared to those without multimorbidity.
BMC INFECTIOUS DISEASES
(2021)
Article
Medicine, General & Internal
Carlota Dobano et al.
Summary: The study found that antibody responses to SARS-CoV-2 can last over 12.5 months in some individuals, with correlations to factors such as fever, hospitalization, and occupation. Among healthcare workers who had not been vaccinated, the positivity rate for spike antigens was very high.
Article
Multidisciplinary Sciences
Dami A. Collier et al.
Summary: Elderly individuals, especially those above eighty, show lower immune responses and neutralization abilities against variants of concern after the first vaccine dose, but this improves after the second dose. They have higher frequencies of spike-specific memory B cells but reduced somatic hypermutation of class-switched cells. Production of interferon-gamma and interleukin-2 by SARS-CoV-2 spike-specific T cells is lower in older participants, predominantly by CD4 T cells.
Review
Immunology
Beatrice Laupeze et al.
Summary: Vaccination aims to prevent pathogen-specific infections, while also improving immune fitness and promoting healthy aging. Life-course vaccination is a fundamental tool for achieving better health outcomes and resilience in the immune system.
Review
Public, Environmental & Occupational Health
Iris Szu-Szu Ho et al.
Summary: This review examined the definition and measurement of multimorbidity in international peer-reviewed studies, finding a high variability in both aspects. Consistent reporting of measure definitions should be required by journals, and consensus studies are needed to define core and study-dependent conditions to include in measures of multimorbidity.
LANCET PUBLIC HEALTH
(2021)
Review
Medicine, General & Internal
Ahmed Hossain et al.
Summary: This study reveals significant regional variations in the prevalence of SARS-CoV-2 antibodies among healthcare workers in Europe, the United States, and East Asia. The patterns of IgG antibodies differ by time, age, and gender, reflecting noticeable differences in virus transmission. Priority for vaccination should be given to older healthcare workers in Europe and East Asia, while measures are needed to prevent hospital spread among HCWs in the USA with high rates of past infections. Routine testing for SARS-CoV-2 in healthcare workers is recommended even after vaccination rollout to identify areas of increased transmission.
Review
Multidisciplinary Sciences
Florian Krammer
Article
Microbiology
Jeffrey Seow et al.
NATURE MICROBIOLOGY
(2020)
Review
Immunology
Joerg J. Goronzy et al.
Article
Public, Environmental & Occupational Health
Ingibjorg H. Jonsdottir et al.
Article
Primary Health Care
Jose M. Valderas et al.
ANNALS OF FAMILY MEDICINE
(2009)
Review
Multidisciplinary Sciences
Stephen J. Galli et al.
