4.7 Article

COVID-19 Vaccine Acceptance and Hesitancy among Healthcare Workers in Lusaka, Zambia; Findings and Implications for the Future

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VACCINES (2022)

Article Infectious Diseases

Co-Infections, Secondary Infections, and Antimicrobial Use in Patients Hospitalized with COVID-19 during the First Five Waves of the Pandemic in Pakistan; Findings and Implications

Kiran Ramzan et al.

Summary: Excessive prescribing of antibiotics is still occurring among COVID-19 patients in Pakistan, but rates are reducing. Urgent measures are needed for further reductions.

ANTIBIOTICS-BASEL (2022)

Article Infectious Diseases

Exploring Knowledge of Antibiotic Use, Resistance, and Stewardship Programs among Pharmacy Technicians Serving in Ambulatory Care Settings in Pakistan and the Implications

Zia Ul Mustafa et al.

Summary: Pharmacy technicians in ambulatory healthcare settings in Pakistan have adequate awareness of antibiotic use, but lack understanding of antimicrobial resistance (AMR) and antimicrobial stewardship programs (ASPs).

ANTIBIOTICS-BASEL (2022)

Article Public, Environmental & Occupational Health

COVID-19 Vaccine Hesitancy Among Health Care Workers in Thailand: The Comparative Results of Two Cross-Sectional Online Surveys Before and After Vaccine Availability

Chatkamol Pheerapanyawaranun et al.

Summary: This study examined COVID-19 vaccine acceptance among healthcare workers in Thailand before and after the vaccines became available. The study found that factors such as age, gender, work region, and occupation had an impact on vaccine hesitancy. The findings of this study can help inform policies aimed at reducing vaccine hesitancy.

FRONTIERS IN PUBLIC HEALTH (2022)

Article Immunology

Coronavirus Disease 2019 (COVID-19) Pandemic across Africa: Current Status of Vaccinations and Implications for the Future

Olayinka O. Ogunleye et al.

Summary: The introduction of effective COVID-19 vaccines in December 2020 was a significant step forward in the global response to the pandemic. This exploratory study investigates the current status of vaccine uptake, challenges, and lessons learnt across 14 African countries. The study found variations in vaccine coverage, with low rates in some countries and increased hesitancy due to misinformation. Governments need to address vaccine hesitancy through targeted interventions among healthcare workers, journalists, and the public.

VACCINES (2022)

Article Infectious Diseases

Determinants of the Empiric Use of Antibiotics by General Practitioners in South Africa: Observational, Analytic, Cross-Sectional Study

Sinenhlanhla Pearl Guma et al.

Summary: The overuse of antibiotics and the lack of surveillance on antibiotic prescribing at a primary healthcare level in South Africa are significant issues. A study found that private sector general practitioners often prescribe antibiotics empirically for patients with acute respiratory infections, primarily for symptom relief and complication prevention. Factors such as age, years of practice, workload/time pressures, and diagnostic uncertainty were associated with empiric prescribing.

ANTIBIOTICS-BASEL (2022)

Article Public, Environmental & Occupational Health

Awareness and acceptance of COVID-19 vaccines and associated factors among pharmacy students in Zambia

Steward Mudenda et al.

Summary: This study assessed the awareness and acceptance of COVID-19 vaccines among pharmacy students in Zambia and found significant vaccine hesitancy. Being of Christian faith was associated with reduced awareness of the vaccines. Factors such as gender, marital status, and employment status were associated with the acceptance of the vaccines.

MALAWI MEDICAL JOURNAL (2022)

Article Medicine, General & Internal

COVID-19 vaccine hesitancy amongst healthcare workers: An assessment of its magnitude and determinants during the initial phase of national vaccine deployment in Nigeria

Terna Nomhwange et al.

Summary: While most healthcare workers in Nigeria have confidence in and have received the COVID-19 vaccines, there is still hesitancy among a minority, mainly due to safety concerns and negative information from social media.

ECLINICALMEDICINE (2022)

Article Primary Health Care

COVID-19 vaccine acceptance and hesitancy among primary healthcare workers in Singapore

Sky Wei Chee Koh et al.

Summary: COVID-19 vaccine acceptance is high among primary healthcare workers in Singapore, with a rate close to 95%. Vaccine acceptance is not significantly influenced by factors such as gender, age, profession, years in healthcare, living alone, chronic diseases, self-perceived risk, or previous influenza vaccination. Personal protection and job-related risk are the top reasons for vaccine acceptance.

BMC PRIMARY CARE (2022)

Article Immunology

The First 100 Days of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Control in Vietnam

Pham Quang Thai et al.

Summary: Vietnam has successfully controlled the spread of SARS-CoV-2 through early introduction of mass communication, meticulous contact tracing, strict quarantine, and international travel restrictions. The high proportion of asymptomatic and imported cases, along with evidence for substantial presymptomatic transmission, support the value of these interventions.

CLINICAL INFECTIOUS DISEASES (2021)

Editorial Material Pediatrics

Vaccine hesitancy in low- and middle-income countries: potential implications for the COVID-19 response

Sunil Bhopal et al.

ARCHIVES OF DISEASE IN CHILDHOOD (2021)

Article Biochemistry & Molecular Biology

A global survey of potential acceptance of a COVID-19 vaccine

Jeffrey V. Lazarus et al.

Summary: Survey data from 19 countries reveals varying attitudes towards acceptance of a COVID-19 vaccine, with trust in government being linked to vaccine confidence.

NATURE MEDICINE (2021)

Review Pediatrics

Things must not fall apart: the ripple effects of the COVID-19 pandemic on children in sub-Saharan Africa

Modupe Coker et al.

Summary: Children aged zero to 19 in sub-Saharan Africa bear a disproportionate burden of global communicable and non-communicable diseases. The COVID-19 pandemic has significantly impacted child health and major disease control efforts, highlighting social and ethical issues. More research and action are needed to mitigate the pandemic's ripple effects on this population.

PEDIATRIC RESEARCH (2021)

Article Immunology

Assessment of US Healthcare Personnel Attitudes Towards Coronavirus Disease 2019 (COVID-19) Vaccination in a Large University Healthcare System

Jana Shaw et al.

Summary: The study found that willingness to receive COVID-19 vaccination varies among healthcare personnel based on hospital roles, with physicians and research scientists exhibiting the highest acceptance. These findings highlight important heterogeneity in personal attitudes among HCPs around COVID-19 vaccines and emphasize the need for tailored communication strategies.

CLINICAL INFECTIOUS DISEASES (2021)

Review Infectious Diseases

Antibiotic prescribing in patients with COVID-19: rapid review and meta-analysis

Bradley J. Langford et al.

Summary: The study estimated that approximately three-quarters of patients with COVID-19 receive antibiotic treatment, which is significantly higher than the estimated prevalence of bacterial co-infection. This suggests a potential for high rates of unnecessary antibiotic use in patients with COVID-19.

CLINICAL MICROBIOLOGY AND INFECTION (2021)

Article Infectious Diseases

COVID-19 vaccine acceptance, hesitancy, and determinants among physicians in a university-based teaching hospital in Thailand

May Sirikalyanpaiboon et al.

Summary: The study revealed a high rate of physician willingness to take the COVID-19 vaccine in Thailand, especially among staff, but a significant proportion would not currently suggest vaccination to their families or patients. Vaccine hesitancy was associated with negative attitudes towards vaccination due to factors such as preferences for specific vaccines, vaccine literacy, uncertainty about vaccine efficacy, and fear of adverse events.

BMC INFECTIOUS DISEASES (2021)

Editorial Material Medicine, General & Internal

Vaccine hesitancy of the COVID-19 by health care personnel

Sukran Kose et al.

Summary: The study revealed that the majority of healthcare professionals are willing to be vaccinated against COVID-19, especially men, students, younger individuals, and those who have had a flu shot. Efforts to increase their knowledge about the new vaccine and address their concerns are crucial.

INTERNATIONAL JOURNAL OF CLINICAL PRACTICE (2021)

Article Medicine, General & Internal

Who should be prioritized for COVID-19 vaccination in China? A descriptive study

Juan Yang et al.

Summary: Based on utilitarian and egalitarian principles, the study defined the target populations and priority levels for a COVID-19 vaccination program in different phases to maximize vaccination effectiveness. Essential workers were prioritized in the early stage, followed by older adults, individuals with underlying health conditions, and pregnant women, and later extended to adults and children without underlying health conditions.

BMC MEDICINE (2021)

Review Endocrinology & Metabolism

Management of patients with diabetes and obesity in the COVID-19 era: Experiences and learnings from South and East Europe, the Middle East, and Africa

Francesco Giorgino et al.

Summary: This article discusses the challenges of managing diabetes and obesity during and post the COVID-19 pandemic. Experts from various regions highlighted the importance of timely and effective disease management, the use of novel therapies, and the prevention of complications. The experiences shared in this panel should impact future clinical guidelines.

DIABETES RESEARCH AND CLINICAL PRACTICE (2021)

Article Environmental Sciences

Low COVID-19 Vaccine Acceptance Is Correlated with Conspiracy Beliefs among University Students in Jordan

Malik Sallam et al.

Summary: The study aimed to evaluate COVID-19 vaccine acceptance among university students in Jordan and found an association between vaccine conspiracy beliefs and vaccine hesitancy.

INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH (2021)

Editorial Material Critical Care Medicine

COVID-19: a heavy toll on health-care workers

Sangeeta Mehta et al.

LANCET RESPIRATORY MEDICINE (2021)

Article Psychology, Biological

Integrated vaccination and physical distancing interventions to prevent future COVID-19 waves in Chinese cities

Bo Huang et al.

Summary: Vaccination combined with physical distancing can effectively control resurgences of COVID-19, especially in cities with high population density. Vaccination can reduce the duration of physical distancing, while moderate physical distancing measures can effectively control infection numbers in high-density cities.

NATURE HUMAN BEHAVIOUR (2021)

Article Public, Environmental & Occupational Health

COVID-19 Vaccination Did Not Change the Personal Protective Behaviors of Healthcare Workers in China

Nan Zhang et al.

Summary: This study found that healthcare workers with higher education levels had lower fear of being infected with SARS-CoV-2 and reported less negative impact of the pandemic on their patient treatment. However, HCWs with a higher education level had better knowledge of COVID-19 but worse personal protective behaviors, showing that with increasing work experience, HCWs gradually relaxed their personal protective behaviors. Additionally, vaccination reduced the negative effects of the COVID-19 pandemic on how the HCWs treated patients. The survey also revealed that after vaccination, HCWs in China did not relax their personal protective behaviors, potentially reducing the risk of subsequent waves of variant virus.

FRONTIERS IN PUBLIC HEALTH (2021)

Article Public, Environmental & Occupational Health

COVID-19 Vaccine Hesitancy on Social Media: Building a Public Twitter Data Set of Antivaccine Content, Vaccine Misinformation, and Conspiracies

Goran Muric et al.

Summary: This paper introduces a dataset of Twitter posts and accounts with strong antivaccine opinions, which is made available to the research community. The accounts in the dataset lean toward the conservative side of the political spectrum and share misinformation from websites with questionable credibility. Understanding vaccine hesitancy through social media is crucial for combating misinformation and promoting vaccination campaigns.

JMIR PUBLIC HEALTH AND SURVEILLANCE (2021)

Article Virology

The COVID-19 vaccine development: A pandemic paradigm

Diego C. Carneiro et al.

Summary: The COVID-19 pandemic has caused significant social and economic disruptions, prompting a global effort to develop effective vaccines. Designing and developing vaccines involves multiple stages, including selecting appropriate platforms, conducting clinical trials, and scaling up production. The world is facing various challenges in combating the pandemic, requiring collaborative efforts to overcome them.

VIRUS RESEARCH (2021)

Article Public, Environmental & Occupational Health

Knowledge, attitude, and acceptance of healthcare workers and the public regarding the COVID-19 vaccine: a cross-sectional study

Muhammed Elhadi et al.

Summary: The study found that while most participants expressed concerns about potential complications of the COVID-19 vaccine, the majority were willing to take the vaccine, especially if its efficacy was 90% or higher.

BMC PUBLIC HEALTH (2021)

Article Environmental Sciences

The impact of the COVID-19 pandemic on socio-economic and sustainability

Xueli Wei et al.

Summary: The COVID-19 pandemic has had a significant impact on the global economy and social well-being, causing issues in employment, poverty, food security, and other aspects.

ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH (2021)

Article Biochemistry & Molecular Biology

COVID-19 vaccine acceptance and hesitancy in low- and middle-income countries

Julio S. Solis Arce et al.

Summary: The acceptance of COVID-19 vaccines in LMICs is higher compared to the United States and Russia, with a focus on personal protection and concerns about side effects. Healthcare workers are the most trusted sources of guidance in LMICs for COVID-19 vaccines, suggesting that prioritizing vaccine distribution to these countries could help advance global immunization coverage.

NATURE MEDICINE (2021)

Article Multidisciplinary Sciences

Health care workers intention to accept COVID-19 vaccine and associated factors in southwestern Ethiopia, 2021

Abiy Tadesse Angelo et al.

Summary: In this study, the intention of health care workers to accept the COVID-19 vaccine was found to be low. Professional types, history of chronic illness, perceived degree of risk of COVID-19 infection, attitude toward COVID-19, and preventive practices were identified as factors influencing the intention of health care workers to accept the COVID-19 vaccine.

PLOS ONE (2021)

Editorial Material Public, Environmental & Occupational Health

Online misinformation and vaccine hesitancy

Renee Garett et al.

Summary: While vaccination rates have increased globally, the rise in nonmedical exemptions for vaccination may lead to a resurgence of vaccine-preventable diseases. Vaccine hesitancy is a significant factor in declining vaccination rates, and strategies to correct misinformation are needed. Health experts and the medical community can use language that appeals to individuals while enforcing policies against vaccine misinformation, and AI tools may play a role in addressing misinformation.

TRANSLATIONAL BEHAVIORAL MEDICINE (2021)

Article Immunology

Attitudes towards the COVID-19 Vaccine and Willingness to Get Vaccinated among Healthcare Workers in French Guiana: The Influence of Geographical Origin

Nicolas Vignier et al.

Summary: This study investigated the willingness to be vaccinated against COVID-19 among Health Care Workers (HCWs) in French Guiana, revealing that most HCWs are willing or have already received the vaccine. Nurses or other non-medical professionals, HCWs born in French Guiana, and those concerned about side effects are less likely to be vaccinated.

VACCINES (2021)

Article Public, Environmental & Occupational Health

COVID-19 Vaccination Acceptance Among Healthcare Workers and Non-healthcare Workers in China: A Survey

Ming-Wei Wang et al.

Summary: Healthcare workers are more willing to be vaccinated against COVID-19, while non-healthcare workers tend to be more hesitant. Vaccine acceptance is influenced by factors such as gender, geographical location, and personal income.

FRONTIERS IN PUBLIC HEALTH (2021)

Article Public, Environmental & Occupational Health

Economic Impact of COVID-19 lockdown on households

Francis Fatoye et al.

Summary: This study evaluated the economic impact of the COVID-19 lockdown on individuals and households, finding that it led to increased household expenditures, particularly on items like hand sanitizers and face masks. Continuing COVID-19 restrictions could have significant economic consequences for households and the health system.

PAN AFRICAN MEDICAL JOURNAL (2021)

Review Medicine, General & Internal

Impact of COVID-19 pandemic on routine immunization

Martin O. C. Ota et al.

Summary: The COVID-19 pandemic has significantly impacted global immunization services, leading to interruptions in routine childhood immunization in many regions and countries. While immunization rates have shown some recovery, a substantial number of vulnerable individuals remain unvaccinated. Catch-up vaccination campaigns are necessary to address existing shortfalls in vaccine uptake. Guidance to mitigate these effects continues to evolve.

ANNALS OF MEDICINE (2021)

Review Medicine, General & Internal

Effectiveness of public health measures in reducing the incidence of covid-19, SARS-CoV-2 transmission, and covid-19 mortality: systematic review and meta-analysis

Stella Talic et al.

Summary: This systematic review and meta-analysis suggest that personal protective and social measures like handwashing, mask wearing, and physical distancing are associated with reductions in the incidence of COVID-19. However, due to heterogeneity of the studies, meta-analysis for other interventions like quarantine, isolation, universal lockdowns, and closures was not possible, and further research is needed.

BMJ-BRITISH MEDICAL JOURNAL (2021)

Review Medicine, General & Internal

Attitudes, acceptance and hesitancy among the general population worldwide to receive the COVID-19 vaccines and their contributing factors: A systematic review

Fidelia Cascini et al.

Summary: Acceptance rates of COVID-19 vaccines vary significantly between countries and time points, with Arabian countries showing higher hesitancy rates. Factors contributing to hesitancy include negative perceptions of vaccine efficacy, safety, convenience, and price. Certain socio-demographic groups identified with lower vaccine acceptance rates include women, younger participants, and individuals with lower education level, income, insurance coverage, living in rural areas, and identifying as racial/ethnic minorities.

ECLINICALMEDICINE (2021)

Article Public, Environmental & Occupational Health

Determinants of intention to get vaccinated against COVID-19 among healthcare personnel in hospitals in Greece

Helena C. Maltezou et al.

Summary: A cross-sectional survey conducted among healthcare personnel in Greece found that 51.1% stated their intention to get vaccinated against COVID-19 while 48.9% stated their intention to decline vaccination. Factors associated with higher intention to get vaccinated included male gender, being a physician, and history of complete vaccination against certain diseases, while factors associated with lower intention included no prior vaccination against influenza and no intention to recommend COVID-19 vaccination to high-risk patients. Urgent efforts are needed to improve safety perception towards COVID-19 vaccines and increase vaccine uptake rates among healthcare personnel to protect the healthcare workforce and services.

INFECTION DISEASE & HEALTH (2021)

Review Health Policy & Services

The Nature and Extent of COVID-19 Vaccination Hesitancy in Healthcare Workers

Nirbachita Biswas et al.

Summary: COVID-19 vaccines have been approved for public use globally, but studies show healthcare workers globally exhibit vaccine hesitancy due to concerns about safety, efficacy, and side effects. Males, older individuals, and those with doctoral degrees (i.e., physicians) are more likely to accept vaccines, and factors like perceived risk, patient care involvement, and influenza vaccination history increase vaccine uptake likelihood. Strategies to improve communication, education, and mandates for clinical workers are crucial to address the high prevalence of vaccine hesitancy in healthcare workers. Healthcare workers play a key role in pandemic mitigation, serving as role models for preventive behaviors and facilitating vaccination efforts.

JOURNAL OF COMMUNITY HEALTH (2021)

Article Health Policy & Services

Assessing the efficiency of Malaysia health system in COVID-19 prevention and treatment response

Nurhafiza Md Hamzah et al.

Summary: The study investigated the relative efficiency level of managing COVID-19 in Malaysia, finding that the inefficiency of medical care processes is the main cause of overall inefficiency, with high-density areas performing well in community surveillance and medical care II processes, while low-density areas perform better in medical care I process. The health system in Malaysia showed good overall performance and effective resource allocation during this challenging period of pandemic response.

HEALTH CARE MANAGEMENT SCIENCE (2021)

Editorial Material Medicine, General & Internal

How covid-19 is accelerating the threat of antimicrobial resistance

Jeremy Hsu

BMJ-BRITISH MEDICAL JOURNAL (2020)

Editorial Material Medicine, General & Internal

Prevention and control of non-communicable diseases in the COVID-19 response

Hans Henri P. Kluge et al.

LANCET (2020)

Article Medicine, General & Internal

Trust in Public Health Is Essential Amid the COVID-19 Pandemic

Marianne Udow-Phillips et al.

JOURNAL OF HOSPITAL MEDICINE (2020)

Article Medicine, General & Internal

Effect of Hydroxychloroquine in Hospitalized Patients with Covid-19

Peter Horby et al.

NEW ENGLAND JOURNAL OF MEDICINE (2020)

News Item Medicine, General & Internal

Covid-19: Remdesivir has little or no impact on survival, WHO trial shows

Owen Dyer

BMJ-BRITISH MEDICAL JOURNAL (2020)

Review Public, Environmental & Occupational Health

Infection and mortality of healthcare workers worldwide from COVID-19: a systematic review

Soham Bandyopadhyay et al.

BMJ GLOBAL HEALTH (2020)

Review Cardiac & Cardiovascular Systems

Types of sampling in research

Pooja Bhardwaj

JOURNAL OF THE PRACTICE OF CARDIOVASCULAR SCIENCES (2019)

News Item Medicine, General & Internal

Measles outbreak in Somali American community follows anti-vaccine talks

Owen Dyer

BMJ-BRITISH MEDICAL JOURNAL (2017)

News Item Medicine, General & Internal

Measles outbreak in Somali American community follows anti-vaccine talks

Owen Dyer

BMJ-BRITISH MEDICAL JOURNAL (2017)

Letter Public, Environmental & Occupational Health

Disease Priorities in Zambia

Duncan Mara

AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE (2016)

Article Immunology

Vaccine hesitancy: Definition, scope and determinants

Noni E. MacDonald

VACCINE (2015)

Article Anthropology

Sterilizing vaccines or the politics of the womb: Retrospective study of a rumor in Cameroon

P Feldman-Savelsberg et al.

MEDICAL ANTHROPOLOGY QUARTERLY (2000)