4.7 Article

Designing a Multi-Epitope Subunit Vaccine against VP1 Major Coat Protein of JC Polyomavirus

Related references

Note: Only part of the references are listed.
Article Biochemistry & Molecular Biology

NPCDR: natural product-based drug combination and its disease-specific molecular regulation

Xueni Sun et al.

Summary: Natural products have a long history in drug discovery and are now being combined with other therapeutic strategies. The newly developed NPCDR database provides comprehensive information on NP-based drug combinations and disease-specific molecular regulation data. It is expected to have great implications for network pharmacology, medical biochemistry, drug design, and medicinal chemistry.

NUCLEIC ACIDS RESEARCH (2022)

Article Biology

Prediction and analysis of multi epitope based vaccine against Newcastle disease virus based on haemagglutinin neuraminidase protein

Adnan Raza et al.

Summary: A multi-epitope vaccine against 26 strains of Newcastle disease virus from Pakistan was designed using immunoinformatic approaches. The vaccine exhibited high immunogenicity, stability, and potential to induce a strong immune response.

SAUDI JOURNAL OF BIOLOGICAL SCIENCES (2022)

Article Immunology

Immunoinformatics approach for a novel multi-epitope subunit vaccine design against various subtypes of Influenza A virus

Shipra Sharma et al.

Summary: This study presents a universal influenza subunit vaccine based on conserved epitopic sequences, aiming to induce innate, cellular, and humoral immune responses. Analysis of physicochemical properties and prediction of a stable model validate the potential effectiveness of the vaccine in protecting against various strains of influenza A virus subtypes.

IMMUNOBIOLOGY (2021)

Review Cell Biology

COVID-19 and Toll-Like Receptor 4 (TLR4): SARS-CoV-2 May Bind and Activate TLR4 to Increase ACE2 Expression, Facilitating Entry and Causing Hyperinflammation

Mohamed M. Aboudounya et al.

Summary: Mortality in COVID-19 is caused by respiratory failure, heart failure, and sepsis/multiorgan failure. TLR4, an innate immune receptor, recognizes viral proteins and triggers immune responses. SARS-CoV-2 binds to TLR4, potentially leading to inflammation and multi-organ injury.

MEDIATORS OF INFLAMMATION (2021)

Article Oncology

TLR4-Mediated Recognition of Mouse Polyomavirus Promotes Cancer-Associated Fibroblast-Like Phenotype and Cell Invasiveness

Vaclav Janovec et al.

Summary: The study indicates that mouse polyomavirus induces a cancer-associated fibroblast (CAF)-like phenotype in mouse fibroblasts through a TLR4-driven inflammatory response, increasing cell invasiveness.

CANCERS (2021)

Article Immunology

Promising role of defensins peptides as therapeutics to combat against viral infection

Subhash Singh Solanki et al.

Summary: Antimicrobial peptides (AMPs) are important molecules in the innate immune system, particularly defensins which have a wide range of antimicrobial activities. They not only combat various infections but also stimulate the host immune system against viruses, showing promising therapeutic potential in fighting viral infections.

MICROBIAL PATHOGENESIS (2021)

Article Biochemistry & Molecular Biology

Delineating the interaction of combretastatin A-4 with αβ tubulin isotypes present in drug resistant human lung carcinoma using a molecular modeling approach

Bajarang Vasant Kumbhar et al.

JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS (2020)

Article Infectious Diseases

Immunoselective algorithm to devise multi-epitope subunit vaccine fighting against human cytomegalovirus infection

Rajan Kumar Pandey et al.

INFECTION GENETICS AND EVOLUTION (2020)

Review Virology

Fifty Years of JC Polyomavirus: A Brief Overview and Remaining Questions

Abigail L. Atkinson et al.

VIRUSES-BASEL (2020)

Article Biochemistry & Molecular Biology

Vaccination and immunization strategies to design Aedes aegypti salivary protein based subunit vaccine tackling Flavivirus infection

Rajan Kumar Pandey et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2019)

Review Biochemistry & Molecular Biology

B Cell Responses: Cell Interaction Dynamics and Decisions

Jason G. Cyster et al.

Article Multidisciplinary Sciences

Designing a multi-epitope based vaccine to combat Kaposi Sarcoma utilizing immunoinformatics approach

Varun Chauhan et al.

SCIENTIFIC REPORTS (2019)

Article Biochemistry & Molecular Biology

Designing B- and T-cell multi-epitope based subunit vaccine using immunoinformatics approach to control Zika virus infection

Rajan Kumar Pandey et al.

JOURNAL OF CELLULAR BIOCHEMISTRY (2018)

Editorial Material Virology

JC Polyomavirus: Let's Please Respect Privacy

Michael J. Imperiale

JOURNAL OF VIROLOGY (2018)

Article Biochemistry & Molecular Biology

MEGA X: Molecular Evolutionary Genetics Analysis across Computing Platforms

Sudhir Kumar et al.

MOLECULAR BIOLOGY AND EVOLUTION (2018)

Letter Immunology

Multi-epitope vaccines: a promising strategy against tumors and viral infections

Lifang Zhang

CELLULAR & MOLECULAR IMMUNOLOGY (2018)

Article Infectious Diseases

Immunoinformatics analysis and in silico designing of a novel multi-epitope peptide vaccine against Staphylococcus aureus

Nasim Hajighahramani et al.

INFECTION GENETICS AND EVOLUTION (2017)

Article Microbiology

JC Polyomavirus Attachment and Entry: Potential Sites for PML Therapeutics

Colleen L. Mayberry et al.

CURRENT CLINICAL MICROBIOLOGY REPORTS (2017)

Article Mathematical & Computational Biology

PIMA: Protein-Protein Interactions in Macromolecular Assembly - a web server for its Analysis and Visualization

Oommen Kaleeckal Mathew et al.

BIOINFORMATION (2016)

Review Clinical Neurology

Persistence and Pathogenesis of the Neurotropic Polyomavirus JC

Hassen S. Wollebo et al.

ANNALS OF NEUROLOGY (2015)

Article Biochemistry & Molecular Biology

The immune epitope database (IEDB) 3.0

Randi Vita et al.

NUCLEIC ACIDS RESEARCH (2015)

Article Biochemistry & Molecular Biology

UniProt: a hub for protein information

Alex Bateman et al.

NUCLEIC ACIDS RESEARCH (2015)

Article Biochemical Research Methods

AllergenFP: allergenicity prediction by descriptor fingerprints

Ivan Dimitrov et al.

BIOINFORMATICS (2014)

Article Biochemical Research Methods

AllerTOP - a server for in silico prediction of allergens

Ivan Dimitrov et al.

BMC BIOINFORMATICS (2013)

Article Multidisciplinary Sciences

In Silico Approach for Predicting Toxicity of Peptides and Proteins

Sudheer Gupta et al.

PLOS ONE (2013)

Article Dentistry, Oral Surgery & Medicine

Defensins and LL-37: a review of function in the gingival epithelium

Ara Greer et al.

PERIODONTOLOGY 2000 (2013)

Article Biochemistry & Molecular Biology

GalaxyWEB server for protein structure prediction and refinement

Junsu Ko et al.

NUCLEIC ACIDS RESEARCH (2012)

Article Biochemical Research Methods

Immune system simulation online

Nicolas Rapin et al.

BIOINFORMATICS (2011)

Review Virology

Human polyoma viruses and disease with emphasis on clinical BK and JC

Raghavender Boothpur et al.

JOURNAL OF CLINICAL VIROLOGY (2010)

Article Biochemistry & Molecular Biology

NetMHC-3.0: accurate web accessible predictions of human, mouse and monkey MHC class I affinities for peptides of length 8-11

Claus Lundegaard et al.

NUCLEIC ACIDS RESEARCH (2008)

Article Biochemistry & Molecular Biology

FireDock: a web server for fast interaction refinement in molecular docking

Efrat Mashiach et al.

NUCLEIC ACIDS RESEARCH (2008)

Article Biochemical Research Methods

VaxiJen: a server for prediction of protective antigens, tumour antigens and subunit vaccines

Irini A. Doytchinova et al.

BMC BIOINFORMATICS (2007)

Article Virology

JC virus evolution and its association with human populations

Laura A. Shackelton et al.

JOURNAL OF VIROLOGY (2006)

Review Biochemistry & Molecular Biology

LL-37, the only human member of the cathelicidin family of antimicrobial peptides

Ulrich H. N. Durr et al.

BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2006)

Review Chemistry, Multidisciplinary

GROMACS: Fast, flexible, and free

D Van der Spoel et al.

JOURNAL OF COMPUTATIONAL CHEMISTRY (2005)

Article Biochemistry & Molecular Biology

PatchDock and SymmDock: servers for rigid and symmetric docking

D Schneidman-Duhovny et al.

NUCLEIC ACIDS RESEARCH (2005)