☆ 4.7 Review

Non-coding RNAs are key players and promising therapeutic targets in atherosclerosis

FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2023)

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miR-145 micelles mitigate atherosclerosis by modulating vascular smooth muscle cell phenotype

Deborah D. Chin et al.

Summary: The delivery of miR-145 micelles to VSMCs shows promise in mitigating atherosclerosis progression by altering cell phenotypes and reducing plaque growth. In mouse experiments, miR-145 micelles significantly inhibited the advancement of atherosclerosis.

BIOMATERIALS (2021)

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Article Cell Biology

Expression profiles and potential roles of transfer RNA-derived small RNAs in atherosclerosis

Xiangqin He et al.

Summary: This study explored the expression profile of tsRNAs in atherosclerosis and their potential roles in regulating cell adhesion molecules pathway. One specific tsRNA, tRF-Gly-GCC, may serve as a promising target for suppressing abnormal vessel functions in the progression of atherosclerosis.

JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2021)

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Article Multidisciplinary Sciences

Loss of SNORA73 reprograms cellular metabolism and protects against steatohepatitis

Arthur C. Sletten et al.

Summary: The study identified SNORA73 as a protective factor against lipotoxicity and oxidative stress, showing that its deficiency leads to metabolic reprogramming and protection against steatohepatitis in mice. Specifically, disruption of SNORA73 causes resistance to lipid-induced cell death and oxidative stress in cultured cells, with knockdown of SNORA73 in vivo protecting against hepatic steatosis and lipid-induced oxidative stress and inflammation. This demonstrates a role for SNORA73 in regulating metabolism and lipotoxicity.

NATURE COMMUNICATIONS (2021)

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Review Medicine, Research & Experimental

Engineering exosomes for targeted drug delivery

Yujie Liang et al.

Summary: Exosomes can be engineered through genetic and chemical methods for targeted drug delivery, increasing the local concentration of therapeutics and minimizing side effects.

THERANOSTICS (2021)

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Article Cardiac & Cardiovascular Systems

High dose rosuvastatin increases ABCA1 transporter in human atherosclerotic plaques in a cholesterol-independent fashion

Donato Santovito et al.

INTERNATIONAL JOURNAL OF CARDIOLOGY (2020)

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Article Cardiac & Cardiovascular Systems

Lifestyle factors and high-risk atherosclerosis: Pathways and mechanisms beyond traditional risk factors

Katharina Lechner et al.

EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY (2020)

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Article Cell Biology

Adipose-derived mesenchymal stem cells-derived exosome-mediated microRNA-342-5p protects endothelial cells against atherosclerosis

Xiaohui Xing et al.

AGING-US (2020)

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Article Chemistry, Multidisciplinary

Molecularly Engineered Macrophage-Derived Exosomes with Inflammation Tropism and Intrinsic Heme Biosynthesis for Atherosclerosis Treatment

Guanghao Wu et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2020)

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Review Biochemistry & Molecular Biology

Lipid nanocarriers for microRNA delivery

Marcel Scheideler et al.

CHEMISTRY AND PHYSICS OF LIPIDS (2020)

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Review Neurosciences

Role of circular RNAs in brain development and CNS diseases

Suresh L. Mehta et al.

PROGRESS IN NEUROBIOLOGY (2020)

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Review Biochemistry & Molecular Biology

Current Advances in the Diagnostic Imaging of Atherosclerosis: Insights into the Pathophysiology of Vulnerable Plaque

Nataliya V. Mushenkova et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)

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Article Cardiac & Cardiovascular Systems

Smad3 Regulates Neuropilin 2 Transcription by Binding to its 5 ' Untranslated Region

Xiujie Xie et al.

JOURNAL OF THE AMERICAN HEART ASSOCIATION (2020)

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Article Medicine, Research & Experimental

Direct Delivery of Apatite Nanoparticle-Encapsulated siRNA Targeting TIMP-1 for Intractable Abnormal Scars

Masayo Aoki et al.

MOLECULAR THERAPY-NUCLEIC ACIDS (2020)

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Article Biochemistry & Molecular Biology

Ultrasound targeted microbubble destruction assisted exosomal delivery of miR-21 protects the heart from chemotherapy associated cardiotoxicity

Wenqi Sun et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2020)

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Article Cell Biology

Noncanonical inhibition of caspase-3 by a nuclear microRNA confers endothelial protection by autophagy in atherosclerosis

Donato Santovito et al.

SCIENCE TRANSLATIONAL MEDICINE (2020)

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Article Medicine, Research & Experimental

Effects of miR-124-3p regulation of the p38MAPK signaling pathway via MEKK3 on apoptosis and proliferation of macrophages in mice with coronary atherosclerosis

Chuannan Zhai et al.

ADVANCES IN CLINICAL AND EXPERIMENTAL MEDICINE (2020)

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Article Multidisciplinary Sciences

A macrophage-specific lncRNA regulates apoptosis and atherosclerosis by tethering HuR in the nucleus

Viorel Simion et al.

NATURE COMMUNICATIONS (2020)

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Article Pharmacology & Pharmacy

LncRNAs in vascular biology and disease

Viorel Simion et al.

VASCULAR PHARMACOLOGY (2019)

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Review Cell Biology

Exosomes: cell-created drug delivery systems

Anastasia Familtseva et al.

MOLECULAR AND CELLULAR BIOCHEMISTRY (2019)

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Review Cell Biology

Intriguing circles: Conflicts and controversies in circular RNA research

Hui-Min Li et al.

WILEY INTERDISCIPLINARY REVIEWS-RNA (2019)

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Article Medicine, Research & Experimental

Effect of microRNA-133a-3p/matrix metalloproteinase-9 axis on the growth of atherosclerotic vascular smooth muscle cells

Lei Shi et al.

EXPERIMENTAL AND THERAPEUTIC MEDICINE (2019)

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Article Cardiac & Cardiovascular Systems

Genetic associations and regulation of expression indicate an independent role for 14q32 snoRNAs in human cardiovascular disease

Kjell E. J. Hakansson et al.

CARDIOVASCULAR RESEARCH (2019)

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Article Cell Biology

MALAT1/miR-15b-5p/MAPK1 mediates endothelial progenitor cells autophagy and affects coronary atherosclerotic heart disease via mTOR signaling pathway

Ying Zhu et al.

AGING-US (2019)

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Article Medicine, Research & Experimental

Exosomes from nicotine-stimulated macrophages accelerate atherosclerosis through miR-21-3p/PTEN-mediated VSMC migration and proliferation

Jumo Zhu et al.

THERANOSTICS (2019)

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Article Medicine, Research & Experimental

Microrna-145 accelerates the inflammatory reaction through activation of NF-κB signaling in atherosclerosis cells and mice

Li Sheng et al.

BIOMEDICINE & PHARMACOTHERAPY (2018)

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Article Cell Biology

Hsa_Circ_0001275: A Potential Novel Diagnostic Biomarker for Postmenopausal Osteoporosis

Kewei Zhao et al.

CELLULAR PHYSIOLOGY AND BIOCHEMISTRY (2018)

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Review Chemistry, Multidisciplinary

New Technologies for Analysis of Extracellular Vesicles

Huilin Shao et al.

CHEMICAL REVIEWS (2018)

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Article Allergy

MicroRNA

Thomas X. Lu et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2018)

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Article Nanoscience & Nanotechnology

A highly integrated precision nanomedicine strategy to target esophageal squamous cell cancer molecularly and physically

Xin-shuai Wang et al.

NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE (2018)

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Editorial Material Endocrinology & Metabolism

Atherosclerosis Is an Epigenetic Disease

Suowen Xu et al.

TRENDS IN ENDOCRINOLOGY AND METABOLISM (2018)

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Article Oncology

LncRNA HOTAIR influences cell growth, migration, invasion, and apoptosis via the miR-20a-5p/HMGA2 axis in breast cancer

Wenyan Zhao et al.

CANCER MEDICINE (2018)

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Article Medicine, Research & Experimental

Gene Therapy for Neuropathic Pain through siRNA-IRF5 Gene Delivery with Homing Peptides to Microglia

Tomoya Terashima et al.

MOLECULAR THERAPY-NUCLEIC ACIDS (2018)

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Article Cell Biology

Comprehensive analysis of circRNA expression pattern and circRNA-miRNA-mRNA network in the pathogenesis of atnerosclerosis in rabbits

Feng Zhang et al.

AGING-US (2018)

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Article Clinical Neurology

Phenotypic ASCOD characterisations of ischaemic stroke in the young at an urban tertiary care centre

Angela Liu et al.

STROKE AND VASCULAR NEUROLOGY (2018)

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Review Oncology

Non-coding RNA networks in cancer

Eleni Anastasiadou et al.

NATURE REVIEWS CANCER (2018)

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Article Biochemistry & Molecular Biology

Identification of HuR target circular RNAs uncovers suppression of PABPN1 translation by CircPABPN1

Kotb Abdelmohsen et al.

RNA BIOLOGY (2017)

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Article Cell Biology

microRNA-binding proteins: specificity and function

Richard W. Zealy et al.

WILEY INTERDISCIPLINARY REVIEWS-RNA (2017)

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Article Cardiac & Cardiovascular Systems

High miR-124-3p expression identifies smoking individuals susceptible to atherosclerosis

Maurice W. J. de Ronde et al.

ATHEROSCLEROSIS (2017)

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Review Biochemistry & Molecular Biology

RISC assembly: Coordination between small RNAs and Argonaute proteins

Hotaka Kobayashi et al.

BIOCHIMICA ET BIOPHYSICA ACTA-GENE REGULATORY MECHANISMS (2016)

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Article Biochemistry & Molecular Biology

LncRNA-MIF, a c-Myc-activated long non-coding RNA, suppresses glycolysis by promoting Fbxw7-mediated c-Myc degradation

Pengfei Zhang et al.

EMBO REPORTS (2016)

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Article Cardiac & Cardiovascular Systems

Gender-Related Differences in Atherosclerosis

Pankaj Mathur et al.

CARDIOVASCULAR DRUGS AND THERAPY (2015)

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Article Cell Biology

snoRNA U17 Regulates Cellular Cholesterol Trafficking

Sarah Jinn et al.

CELL METABOLISM (2015)

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Article Chemistry, Multidisciplinary

Evaluation of dendrimer type bio-reducible polymer as a siRNA delivery carrier for cancer therapy

Joung-Pyo Nam et al.

JOURNAL OF CONTROLLED RELEASE (2015)

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Article Genetics & Heredity

Non-coding RNA: what is functional and what is junk?

Alexander F. Palazzo et al.

FRONTIERS IN GENETICS (2015)

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Article Cardiac & Cardiovascular Systems

MicroRNA-133a regulates insulin-like growth factor-1 receptor expression and vascular smooth muscle cell proliferation in murine atherosclerosis

Song Gao et al.

ATHEROSCLEROSIS (2014)

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Article Medicine, Research & Experimental

Long-term therapeutic silencing of miR-33 increases circulating triglyceride levels and hepatic lipid accumulation in mice

Leigh Goedeke et al.

EMBO MOLECULAR MEDICINE (2014)

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Article Cell Biology

Lipid rafts couple class A scavenger receptors to phospholipase A2 activation during macrophage adhesion

Shanthi Vadali et al.

JOURNAL OF LEUKOCYTE BIOLOGY (2014)

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Article Biochemistry & Molecular Biology

MicroRNA-126-5p promotes endothelial proliferation and limits atherosclerosis by suppressing Dlk1

Andreas Schober et al.

NATURE MEDICINE (2014)

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Review Immunology

Macrophages in atherosclerosis: a dynamic balance

Kathryn J. Moore et al.

NATURE REVIEWS IMMUNOLOGY (2013)

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Article Medicine, Research & Experimental

miR-33 controls the expression of biliary transporters, and mediates statin- and diet-induced hepatotoxicity

Ryan M. Allen et al.

EMBO MOLECULAR MEDICINE (2012)

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Article Cardiac & Cardiovascular Systems

miR-21, miR-210, miR-34a, and miR-146a/b are up-regulated in human atherosclerotic plaques in the Tampere Vascular Study

Emma Raitoharju et al.

ATHEROSCLEROSIS (2011)

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Article Biochemistry & Molecular Biology

A ceRNA Hypothesis: The Rosetta Stone of a Hidden RNA Language?

Leonardo Salmena et al.

CELL (2011)

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Article Biotechnology & Applied Microbiology

Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes

Lydia Alvarez-Erviti et al.

NATURE BIOTECHNOLOGY (2011)

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Article Multidisciplinary Sciences

miR-33 links SREBP-2 induction to repression of sterol transporters

Tyler J. Marquart et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)

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Article Multidisciplinary Sciences

MiR-33 Contributes to the Regulation of Cholesterol Homeostasis

Katey J. Rayner et al.

SCIENCE (2010)

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Article Cardiac & Cardiovascular Systems

Pathogenesis of atherosclerosis

E Falk

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2006)

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Article Oncology

MiR-148a-3p attenuates apoptosis and inflammation by targeting CNTN4 in atherosclerosis

Kai Wang et al.

Summary: The study found that miR-148a-3p can inhibit oxLDL-induced cell apoptosis and inflammation in THP-1 macrophages by targeting the CNTN4 gene.

ANNALS OF TRANSLATIONAL MEDICINE

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