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BRITISH JOURNAL OF CANCER (2015)
Ectopic expression of miR-494 inhibited the proliferation, invasion and chemoresistance of pancreatic cancer by regulating SIRT1 and c-Myc
Y. Liu et al.
GENE THERAPY (2015)
The miR-17-92 cluster counteracts quiescence and chemoresistance in a distinct subpopulation of pancreatic cancer stem cells
Michele Cioffi et al.
GUT (2015)
Long Noncoding RNA MALAT-1 Enhances Stem Cell-Like Phenotypes in Pancreatic Cancer Cells
Feng Jiao et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2015)
The long non-coding RNA HOTTIP promotes progression and gemcitabine resistance by regulating HOXA13 in pancreatic cancer
Zhihua Li et al.
JOURNAL OF TRANSLATIONAL MEDICINE (2015)
Upregulation of microRNA-138-5p inhibits pancreatic cancer cell migration and increases chemotherapy sensitivity
Chao Yu et al.
MOLECULAR MEDICINE REPORTS (2015)
Antisense inhibition of microRNA-21 and microRNA-221 in tumor-initiating stem-like cells modulates tumorigenesis, metastasis, and chemotherapy resistance in pancreatic cancer
Yue Zhao et al.
TARGETED ONCOLOGY (2015)
Identifying microRNA-mRNA regulatory network in gemcitabine-resistant cells derived from human pancreatic cancer cells
Yehua Shen et al.
TUMOR BIOLOGY (2015)
miR-33a suppresses the nuclear translocation of β-catenin to enhance gemcitabine sensitivity in human pancreatic cancer cells
Chen Liang et al.
TUMOR BIOLOGY (2015)
MicroRNA-33a-mediated downregulation of Pim-3 kinase expression renders human pancreatic cancer cells sensitivity to gemcitabine
Chen Liang et al.
ONCOTARGET (2015)
Upregulation of miR-181c contributes to chemoresistance in pancreatic cancer by inactivating the Hippo signaling pathway
Meiyuan Chen et al.
ONCOTARGET (2015)
MicroRNA Profiling Implies New Markers of Gemcitabine Chemoresistance in Mutant p53 Pancreatic Ductal Adenocarcinoma
Sameer A. Dhayat et al.
PLOS ONE (2015)
MicroRNA-1246 expression associated with CCNG2-mediated chemoresistance and stemness in pancreatic cancer
S. Hasegawa et al.
BRITISH JOURNAL OF CANCER (2014)
The TGFβ-miR200-MIG6 Pathway Orchestrates the EMT-Associated Kinase Switch That Induces Resistance to EGFR Inhibitors
Evgeny Izumchenko et al.
CANCER RESEARCH (2014)
MiR-365 induces gemcitabine resistance in pancreatic cancer cells by targeting the adaptor protein SHC1 and pro-apoptotic regulator BAX
Shin Hamada et al.
CELLULAR SIGNALLING (2014)
MicroRNA modulation combined with sunitinib as a novel therapeutic strategy for pancreatic cancer
Marta Passadouro et al.
INTERNATIONAL JOURNAL OF NANOMEDICINE (2014)
Autophagy-a key player in cellular and body metabolism
Kook Hwan Kim et al.
NATURE REVIEWS ENDOCRINOLOGY (2014)
MIR-211 MODULATES GEMCITABINE ACTIVITY THROUGH DOWNREGULATION OF RIBONUCLEOTIDE REDUCTASE AND INHIBITS THE INVASIVE BEHAVIOR OF PANCREATIC CANCER CELLS
Mina Maftouh et al.
NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS (2014)
MicroRNA-100 regulates pancreatic cancer cells growth and sensitivity to chemotherapy through targeting FGFR3
Zhipeng Li et al.
TUMOR BIOLOGY (2014)
MiR-497 downregulation contributes to the malignancy of pancreatic cancer and associates with a poor prognosis
Jianwei Xu et al.
ONCOTARGET (2014)
miR-320c regulates gemcitabine-resistance in pancreatic cancer via SMARCC1
Y. Iwagami et al.
BRITISH JOURNAL OF CANCER (2013)
MicroRNA-29a induces resistance to gemcitabine through the Wnt/β-catenin signaling pathway in pancreatic cancer cells
Hiroaki Nagano et al.
INTERNATIONAL JOURNAL OF ONCOLOGY (2013)
The serum miR-21 level serves as a predictor for the chemosensitivity of advanced pancreatic cancer, and miR-21 expression confers chemoresistance by targeting FasL
Peng Wang et al.
MOLECULAR ONCOLOGY (2013)
miRNA-181b increases the sensitivity of pancreatic ductal adenocarcinoma cells to gemcitabine in vitro and in nude mice by targeting BCL-2
Baobao Cai et al.
ONCOLOGY REPORTS (2013)
Involvement of microRNA-181b in the gemcitabine resistance of pancreatic cancer cells
Daisuke Takiuchi et al.
PANCREATOLOGY (2013)
Differential Processing of let-7a Precursors Influences RRM2 Expression and Chemosensitivity in Pancreatic Cancer: Role of LIN-28 and SET Oncoprotein
Yangzom Doma Bhutia et al.
PLOS ONE (2013)
The role of mesenchymal stem cells in anti-cancer drug resistance and tumour progression
J. M. Houthuijzen et al.
BRITISH JOURNAL OF CANCER (2012)
miR-17-5p Inhibitor Enhances Chemosensitivity to Gemcitabine Via Upregulating Bim Expression in Pancreatic Cancer Cells
Hai-jiao Yan et al.
DIGESTIVE DISEASES AND SCIENCES (2012)
Epigenetic Regulation by Long Noncoding RNAs
Jeannie T. Lee
SCIENCE (2012)
MicroRNA Expression as a Predictive Marker for Gemcitabine Response after Surgical Resection of Pancreatic Cancer
Kenoki Ohuchida et al.
ANNALS OF SURGICAL ONCOLOGY (2011)
Bcl-2 Upregulation Induced by miR-21 Via a Direct Interaction Is Associated with Apoptosis and Chemoresistance in MIA PaCa-2 Pancreatic Cancer Cells
Jie Dong et al.
ARCHIVES OF MEDICAL RESEARCH (2011)
Genome-wide screen identifies PVT1 as a regulator of Gemcitabine sensitivity in human pancreatic cancer cells
Lei You et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2011)
Knockdown of microRNA-21 Inhibits Proliferation and Increases Cell Death by Targeting Programmed Cell Death 4 (PDCD4) in Pancreatic Ductal Adenocarcinoma
Imran Bhatti et al.
JOURNAL OF GASTROINTESTINAL SURGERY (2011)
MicroRNA-21 in Pancreatic Cancer: Correlation with Clinical Outcome and Pharmacologic Aspects Underlying Its Role in the Modulation of Gemcitabine Activity
Elisa Giovannetti et al.
CANCER RESEARCH (2010)
Identification of MicroRNA-21 as a Biomarker for Chemoresistance and Clinical Outcome Following Adjuvant Therapy in Resectable Pancreatic Cancer
Jin-Hyeok Hwang et al.
PLOS ONE (2010)
Pancreatic Cancer-Could It Be that Simple? A Different Context of Vulnerability
Daniel D. Von Hoff et al.
CANCER CELL (2009)
Antisense Inhibition of microRNA-21 or-221 Arrests Cell Cycle, Induces Apoptosis, and Sensitizes the Effects of Gemcitabine in Pancreatic Adenocarcinoma
Jong-Kook Park et al.
PANCREAS (2009)
MicroRNA miR-34 Inhibits Human Pancreatic Cancer Tumor-Initiating Cells
Qing Ji et al.
PLOS ONE (2009)