Related references
Note: Only part of the references are listed.Probing the Mec1ATR Checkpoint Activation Mechanism with Small Peptides
Paulina H. Wanrooij et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2016)
Phosphoproteomics Reveals Distinct Modes of Mec1/ATR Signaling during DNA Replication
Francisco Meirelles Bastos de Oliveira et al.
MOLECULAR CELL (2015)
High-throughput phosphoproteomics reveals in vivo insulin signaling dynamics
Sean J. Humphrey et al.
NATURE BIOTECHNOLOGY (2015)
Common variation at 2p13.3, 3q29, 7p13 and 17q25.1 associated with susceptibility to pancreatic cancer
Erica J. Childs et al.
NATURE GENETICS (2015)
Proteomics reveals dynamic assembly of repair complexes during bypass of DNA cross-links
Markus Raeschle et al.
SCIENCE (2015)
Targeting ATR in DNA damage response and cancer therapeutics
Emmanouil Fokas et al.
CANCER TREATMENT REVIEWS (2014)
Accurate Proteome-wide Label-free Quantification by Delayed Normalization and Maximal Peptide Ratio Extraction, Termed MaxLFQ
Juergen Cox et al.
MOLECULAR & CELLULAR PROTEOMICS (2014)
ProteomeXchange provides globally coordinated proteomics data submission and dissemination
Juan A. Vizcaino et al.
NATURE BIOTECHNOLOGY (2014)
Causes and consequences of replication stress
Michelle K. Zeman et al.
NATURE CELL BIOLOGY (2014)
ATR Prohibits Replication Catastrophe by Preventing Global Exhaustion of RPA
Luis Ignacio Toledo et al.
CELL (2013)
Lagging strand maturation factor Dna2 is a component of the replication checkpoint initiation machinery
Sandeep Kumar et al.
GENES & DEVELOPMENT (2013)
ATR phosphorylates SMARCAL1 to prevent replication fork collapse
Frank B. Couch et al.
GENES & DEVELOPMENT (2013)
A Role for the MRN Complex in ATR Activation via TOPBP1 Recruitment
Anja M. Duursma et al.
MOLECULAR CELL (2013)
The ATM protein kinase: regulating the cellular response to genotoxic stress, and more
Yosef Shiloh et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2013)
Multiplex Genome Engineering Using CRISPR/Cas Systems
Le Cong et al.
SCIENCE (2013)
DNA Damage Sensing by the ATM and ATR Kinases
Alexandre Marechal et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2013)
Two Distinct Modes of ATR Activation Orchestrated by Rad17 and Nbs1
Bunsyo Shiotani et al.
CELL REPORTS (2013)
An Essential Function for the ATR-Activation-Domain (AAD) of TopBP1 in Mouse Development and Cellular Senescence
Zhong-Wei Zhou et al.
PLOS GENETICS (2013)
Human RNF169 is a negative regulator of the ubiquitin-dependent response to DNA double-strand breaks
Maria Poulsen et al.
JOURNAL OF CELL BIOLOGY (2012)
Proteomic Investigations Reveal a Role for RNA Processing Factor THRAP3 in the DNA Damage Response
Petra Beli et al.
MOLECULAR CELL (2012)
Genome-wide association study identifies five loci associated with susceptibility to pancreatic cancer in Chinese populations
Chen Wu et al.
NATURE GENETICS (2012)
DVC1 (C1orf124) is a DNA damage-targeting p97 adaptor that promotes ubiquitin-dependent responses to replication blocks
Anna Mosbech et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2012)
Double-Strand Break End Resection and Repair Pathway Choice
Lorraine S. Symington et al.
ANNUAL REVIEW OF GENETICS, VOL 45 (2011)
53BP1 nuclear bodies form around DNA lesions generated by mitotic transmission of chromosomes under replication stress
Claudia Lukas et al.
NATURE CELL BIOLOGY (2011)
A cell-based screen identifies ATR inhibitors with synthetic lethal properties for cancer-associated mutations
Luis I. Toledo et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2011)
A DNA Damage Response Screen Identifies RHINO, a 9-1-1 and TopBP1 Interacting Protein Required for ATR Signaling
Cecilia Cotta-Ramusino et al.
SCIENCE (2011)
The ATR barrier to replication-born DNA damage
Andres J. Lopez-Contreras et al.
DNA REPAIR (2010)
The DNA Damage Response: Making It Safe to Play with Knives
Alberto Ciccia et al.
MOLECULAR CELL (2010)
ATM-Dependent and -Independent Dynamics of the Nuclear Phosphoproteome After DNA Damage
Ariel Bensimon et al.
SCIENCE SIGNALING (2010)
The SIOD disorder protein SMARCAL1 is an RPA-interacting protein involved in replication fork restart
Alberto Ciccia et al.
GENES & DEVELOPMENT (2009)
The Unstructured C-Terminal Tail of the 9-1-1 Clamp Subunit Ddc1 Activates Mec1/ATR via Two Distinct Mechanisms
Vasundhara M. Navadgi-Patil et al.
MOLECULAR CELL (2009)
The DNA-damage response in human biology and disease
Stephen P. Jackson et al.
NATURE (2009)
TopBP1 activates ATR through ATRIP and a PIKK regulatory domain
Daniel A. Mordes et al.
GENES & DEVELOPMENT (2008)
ATR signaling can drive cells into senescence in the absence of DNA breaks
Luis I. Toledo et al.
GENES & DEVELOPMENT (2008)
The Basic Cleft of RPA70N Binds Multiple Checkpoint Proteins, Including RAD9, To Regulate ATR Signaling
Xin Xu et al.
MOLECULAR AND CELLULAR BIOLOGY (2008)
ATR: an essential regulator of genome integrity
Karlene A. Cimprich et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2008)
The Rad9-Hus1-Rad1 checkpoint interaction of TopBP1 with ATR
Joon Lee et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
The Rad9-Hus1-Rad1 (9-1-1) clamp activates checkpoint signaling via TopBP1
Sinny Delacroix et al.
GENES & DEVELOPMENT (2007)
ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage
Shuhei Matsuoka et al.
SCIENCE (2007)
The human Tim/Tipin complex coordinates an intra-S checkpoint response to UV that slows replication fork displacement
Keziban Unsal-Kacmaz et al.
MOLECULAR AND CELLULAR BIOLOGY (2007)
Spatial organization of the mammalian genome surveillance machinery in response to DNA strand breaks
S Bekker-Jensen et al.
JOURNAL OF CELL BIOLOGY (2006)
Structure and function of ETAA16:: a novel cell surface antigen in Ewing's tumours
A Borowski et al.
CANCER IMMUNOLOGY IMMUNOTHERAPY (2006)
TopBP1 activates the ATR-ATRIP complex
A Kumagai et al.
CELL (2006)
Sulforhodamine B colorimetric assay for cytotoxicity screening
Vanicha Vichai et al.
NATURE PROTOCOLS (2006)
A practical recipe for stable isotope labeling by amino acids in cell culture (SILAC)
Shao-En Ong et al.
NATURE PROTOCOLS (2006)
Functional uncoupling of MCM helicase and DNA polymerase activities activates the ATR-dependent checkpoint
TS Byun et al.
GENES & DEVELOPMENT (2005)
Dial 9-1-1 for DNA damage: the RaO-Hus1-Rad1 (9-1-1) clamp complex
ER Parrilla-Castellar et al.
DNA REPAIR (2004)
Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes
L Zou et al.
SCIENCE (2003)
A splicing mutation affecting expression of ataxia-telangiectasia and Rad3-related protein (ATR) results in Seckel syndrome
M O'Driscoll et al.
NATURE GENETICS (2003)
Regulation of ATR substrate selection by Rad17-dependent loading of Rad9 complexes onto chromatin
L Zou et al.
GENES & DEVELOPMENT (2002)
ATR and ATRIP: Partners in checkpoint signaling
D Cortez et al.
SCIENCE (2001)
Initial steps of ferulic acid polymerization by lignin peroxidase
G Ward et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Genome maintenance mechanisms for preventing cancer
JHJ Hoeijmakers
NATURE (2001)
Significance analysis of microarrays applied to the ionizing radiation response
VG Tusher et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Essential role of BETA2/NeuroD1 in development of the vestibular and auditory systems
M Liu et al.
GENES & DEVELOPMENT (2000)
Structural basis for the recognition of DNA repair proteins UNG2, XPA, and RAD52 by replication factor RPA
G Mer et al.
CELL (2000)
Targeted disruption of the cell-cycle checkpoint gene ATR leads to early embryonic lethality in mice
A de Klein et al.
CURRENT BIOLOGY (2000)
Repair of endogenous DNA damage
T Lindahl et al.
COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY (2000)
Share Paper
