4.8 Editorial Material

How distinct Arp2/3 complex variants regulate actin filament assembly

Journal

NATURE CELL BIOLOGY
Volume 18, Issue 1, Pages 1-3

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NATURE PUBLISHING GROUP
DOI: 10.1038/ncb3293

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The heptameric Arp2/3 complex generates branched actin filament networks that drive lamellipodium protrusion, vesicle trafficking and pathogen motility. Distinct variants of the Arp2/3 complex are now shown to have different roles in tuning actin assembly and disassembly, in concert with the prominent actin regulators cortactin and coronin.

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