Journal
WORLD JOURNAL OF CLINICAL CASES
Volume 11, Issue 27, Pages 6318-6326Publisher
BAISHIDENG PUBLISHING GROUP INC
DOI: 10.12998/wjcc.v11.i27.6318
Keywords
Metabolomics; Amino acid metabolism; Colorectal cancer; Glutamine
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Metabolomics research in cancer screening and treatment has gained attention in recent years. It is a popular technique for quantitatively characterizing small molecular compounds in biological cells, tissues, organs, or organisms. Changes in amino acid metabolism in tumors play a crucial role in their growth and metabolism, making the study of amino acid metabolism characteristics particularly important in colorectal cancer.
In recent years, metabolomics research has become a hot spot in the screening and treatment of cancer. It is a popular technique for the quantitative characterization of small molecular compounds in biological cells, tissues, organs or organisms. Further study of the tumor revealed that amino acid changes may occur early in the tumor. The rapid growth and metabolism required for survival result in tumors exhibiting an increased demand for amino acids. An abundant supply of amino acids is important for cancer to maintain its proliferative driving force. Changes in amino acid metabolism can be used to screen malignant tumors and improve therapeutic outcomes. Therefore, it is particularly important to study the characteristics of amino acid metabolism in colorectal cancer. This article reviews several specific amino acid metabolism characteristics in colorectal cancer.
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