4.6 Review

Photodynamic Inactivation of Opportunistic Premise Plumbing Pathogens and Their Biofilms

Related references

Note: Only part of the references are listed.
Article Oncology

Antimicrobial activity of water-soluble tetra-cationic porphyrins on Pseudomonas aeruginosa

Carolina Gonzalez Urquhart et al.

Summary: This manuscript investigates the cytotoxicity, antimicrobial activity, antibiofilm preliminary properties, and associated therapy of water-soluble tetra-cationic porphyrins against Pseudomonas aeruginosa. The study finds that porphyrin 4H2TMePor exhibits better antimicrobial activity and can inhibit bacterial growth through irradiation. The photosensitizer shows no toxicity to human keratinocytes or mouse fibroblasts. With its excellent antimicrobial and preliminary antibiofilm activity, water-soluble tetra-cationic porphyrins have the potential to be used as a clinical photosensitizer.

PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY (2023)

Article Environmental Sciences

Photodynamic inactivation of microorganisms in different water matrices: The effect of physicochemical parameters on the treatment outcome

Maria Bartolomeu et al.

Summary: This study aimed to evaluate the applicability of photodynamic inactivation (PDI) in real wastewater contexts for microbial inactivation. The results showed that PDI is an effective and promising disinfection method with a bacterial reduction of >3.0 log CFU/mL within the first hour of treatment. However, the physicochemical composition of water matrices should be considered as it can affect PDI efficacy, especially the pH, with acidic conditions showing better PDI performance.

SCIENCE OF THE TOTAL ENVIRONMENT (2023)

Review Infectious Diseases

An Explorative Review on Advanced Approaches to Overcome Bacterial Resistance by Curbing

F. Mohamad et al.

Summary: The emergence of multidrug-resistant pathogens has led to the development of innovative approaches targeting unique virulence factors. Biofilm formation, a crucial virulence factor, reduces the efficacy of antibiotics and evades host immunity. This review discusses the link between biofilm formation and antimicrobial resistance, as well as innovative approaches to combat biofilms using natural compounds, phages, antimicrobial photodynamic therapy, gene editing, and nano-mediated techniques.

INFECTION AND DRUG RESISTANCE (2023)

Article Environmental Sciences

A new acridine-based photosensitizer with ultra-low light requirement efficiently inactivates carbapenem-resistant Acinetobacter baumannii and methicillin-resistant Staphylococcus aureus and degrades their antibiotic resistance genes

Xiaojie Xu et al.

Summary: The spread of antibiotic resistant pathogens and antibiotic resistance genes in the environment is a serious threat to public health. Existing methods are ineffective in removing them, but a new acridine-based photosensitizer called YM-3 has been developed in this study, which can effectively inactivate antibiotic resistant pathogens and reduce antibiotic resistance genes by generating singlet oxygen. YM-3 has shown a high inactivation rate for methicillin-resistant Staphylococcus aureus and carbapenem-resistant Acinetobacter baumannii, and it can effectively reduce the copy numbers of antibiotic resistance genes in these bacteria. It also has a long-lasting bactericidal effect, making it suitable for disinfection in various environments.

ENVIRONMENT INTERNATIONAL (2023)

Review Environmental Sciences

Behaviors and mechanisms of microbially-induced corrosion in metal-based water supply pipelines: A review

Xin Song et al.

Summary: Microbially-induced corrosion (MIC) is a serious issue in drinking water distribution systems, causing pipe leakage and deteriorating water quality. However, the occurrence of MIC in these systems has not been sufficiently discussed, which is the focus of this review. The formation of deposits with microbial capture is proposed as a possible source of MIC in newly constructed DWDSs.

SCIENCE OF THE TOTAL ENVIRONMENT (2023)

Article Engineering, Chemical

UV pretreatment reduced biofouling of ultrafiltration and controlled opportunistic pathogens in secondary water supply systems

Haibo Wang et al.

Summary: This study investigates the effect of UV pretreatment on the removal of opportunistic pathogens and biofouling of UF membranes in secondary water supply systems. The results show that UV pretreatment effectively inactivates opportunistic pathogens and improves the structure of UF membranes, reducing biofouling.

DESALINATION (2023)

Review Environmental Sciences

Bacterial biofilm inhibitors: An overview

Vipin Chandra Kalia et al.

Summary: Bacteria causing infectious diseases use biofilms as a common lifestyle, which makes antibiotics ineffective. Quorum sensing and c-di-GMP are signaling mechanisms that regulate bacterial biofilm formation. The research aims to provide methods for inhibiting biofilm formation and disrupting mature biofilms to aid in the treatment of infectious diseases.

ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY (2023)

Article Engineering, Environmental

Influence of pipe materials on in-building disinfection of P. aeruginosa and A. baumannii in simulated hot water plumbing

Abraham Cullom et al.

Summary: This study evaluated the control effectiveness of different pipe materials and disinfectants on opportunistic pathogens in building water systems. The results showed that the choice of pipe material and disinfectant can influence the growth trend of pathogens and pose challenges in controlling them in certain plumbing systems experiencing warm, stagnant water.

WATER RESEARCH X (2023)

Article Engineering, Environmental

Photo-disinfection processes for bacterial inactivation and underlying principles for water constituents' impact: A review

Jemi Gandhi et al.

Summary: Photo-disinfection processes, including solar disinfection (SODIS), ultraviolet (UV) light disinfection, and light promoted advanced oxidation processes (AOPs), have been extensively studied for bacterial inactivation. Water constituents such as turbidity, pH, dissolved organic matter (DOM), inorganic ions, salinity, temperature, and dissolved oxygen (DO) were found to have positive, negative, or neutral impacts on these photo-disinfection processes, and controlling the constituents in feed water is crucial for effective disinfection.

CHEMICAL ENGINEERING JOURNAL ADVANCES (2023)

Review Environmental Sciences

Porphyrins developed for photoinactivation of microbes in wastewater

Knowledge Siyabonga Ndlovu et al.

Summary: Photodynamic antimicrobial chemotherapy (PACT) is a widely studied strategy to eliminate pathogenic microbes in wastewater. PACT overcomes the limitations of chlorination, ozonation, and ultraviolet irradiation as disinfection methods, which can lead to the development of resistant genes and harmful by-products. PACT utilizes photons, oxygen, and photosensitizers such as porphyrins to generate reactive oxygen species and induce cytotoxic effects on various microbes. This review evaluates the efficacy of porphyrins and porphyrin-conjugates as photosensitizers for wastewater photoinactivation and discusses concerns regarding their application in water treatment, including the recovery and reuse of immobilized photosensitizers.

ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH (2023)

Article Oncology

Nanomolar effective report of tetra-cationic silver(II) porphyrins against non-tuberculous mycobacteria in antimicrobial photodynamic approaches

Kevim Bordignon Guterres et al.

Summary: In this study, the photoinactivation evaluation of Ag(II) porphyrins in the antimicrobial photodynamic therapy of rapidly growing mycobacterial strains was reported. The results showed that Ag(II) porphyrins significantly reduced the concentration of viable mycobacteria and induced potential structural damage.

PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY (2022)

Review Environmental Sciences

Dual-wavelength light radiation for synergistic water disinfection

Galina Matafonova et al.

Summary: The development of narrow-band mercury-free light sources, such as LEDs and excilamps, has led to research on inactivation of pathogenic microorganisms by dual-wavelength light radiation, showing synergistic effects in enhancing microbial inactivation in water. Dual-wavelength light irradiation triggers different inactivation mechanisms involving protein and DNA damage, as well as the generation of reactive oxygen species. Combining different wavelengths of light can potentially be applied in water disinfection processes, making them more energy- and cost-effective.

SCIENCE OF THE TOTAL ENVIRONMENT (2022)

Article Multidisciplinary Sciences

The oxidative stress and metabolic response of Acinetobacter baumannii for aPDT multiple photosensitization

Ewelina Wanarska et al.

Summary: This article describes the use of antimicrobial photodynamic inactivation as a non-antibiotic alternative method to inactivate Acinetobacter baumannii. The study found that phototherapy effectively reduced the number of viable cells and had no significant impact on biofilm formation and antibiotic resistance.

SCIENTIFIC REPORTS (2022)

Article Biochemistry & Molecular Biology

Photodynamic Inactivation of Antibiotic-Resistant and Sensitive Aeromonas hydrophila with Peripheral Pd(II)- vs. Zn(II)-Phthalocyanines

Vanya N. Mantareva et al.

Summary: PhotoDynamic Therapy (PDT) is an effective strategy to combat antimicrobial multidrug resistance (AMR) in pathogenic bacteria. This study demonstrates the efficacy of new Pd(II)- and Zn(II)-phthalocyanine complexes in inactivating Gram-negative bacteria, independent of their antibiotic sensitivity.

BIOMEDICINES (2022)

Article Environmental Sciences

Green phytoextracts as natural photosensitizers in LED-based photodynamic disinfection of multidrug-resistant bacteria in wastewater effluent

M. A. Rashid Sarker et al.

Summary: The photodynamic treatment process using natural photosensitizers from plants showed excellent efficacy in disinfecting multidrug-resistant and total coliforms in wastewater. The generation of reactive oxygen species increased with the irradiation time, playing a key role in the photodynamic disinfection process.

CHEMOSPHERE (2022)

Article Biochemistry & Molecular Biology

Applications of Antimicrobial Photodynamic Therapy against Bacterial Biofilms

Sandile Phinda Songca et al.

Summary: Antimicrobial photodynamic therapy and allied photodynamic antimicrobial chemotherapy have shown remarkable activity against bacterial pathogens in both planktonic and biofilm forms, with little to no resistance development. Furthermore, combination therapies involving antimicrobial photodynamic therapy have demonstrated additive and synergistic enhancement of efficacy.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2022)

Article Oncology

In vitro study of the effect of ALA-PDT on Mycobacterium abscessus and its antibiotic susceptibility

Chenda Yue et al.

Summary: In this study, the effect of photodynamic therapy using 5-aminolevulinic acid (ALA) on Mycobacterium abscessus (M. abscessus) was evaluated. ALA-PDT showed a significant killing effect on M. abscessus and increased its antibiotic susceptibility.

PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY (2022)

Article Oncology

5-aminolevulinic acid-photodynamic therapy ameliorates cutaneous granuloma by killing drug-resistant Mycobacterium marinum

Zhiya Yang et al.

Summary: The study demonstrates the efficacy of ALA-PDT in directly killing M. marinum. The cutaneous lesions caused by M. marinum on mouse paws were fully recovered 4 weeks after ALA-PDT treatment. ALA-PDT was also effective in patients with cutaneous infection caused by drug-resistant M. marinum.

PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY (2022)

Review Environmental Sciences

The Presence of Opportunistic Premise Plumbing Pathogens in Residential Buildings: A Literature Review

Claire Hayward et al.

Summary: Opportunistic premise plumbing pathogens (OPPP) are microorganisms that pose a health risk to immune-compromised individuals in residential water systems. Current drinking water treatment methods are ineffective against many waterborne pathogens. Further research is needed to understand the prevalence of OPPPs in residential water and the incidence of waterborne homecare-associated infections in order to develop effective controls.

WATER (2022)

Article Biochemistry & Molecular Biology

ALA_PDT Promotes Ferroptosis-Like Death of Mycobacterium abscessus and Antibiotic Sterilization via Oxidative Stress

Xiaoyu Wang et al.

Summary: This study investigated the efficacy of ALA_PDT against M. abscessus infections and found that it can kill M. abscessus by promoting ferroptosis-like death and oxidative stress through changes in iron metabolism. Additionally, ALA_PDT disrupted the integrity of the cell membrane and enhanced its permeability. These findings provide new mechanistic insights into the clinical treatment of M. abscessus using ALA_PDT.

ANTIOXIDANTS (2022)

Article Microbiology

Inactivation of Opportunistic Pathogens Acinetobacter baumannii and Stenotrophomonas maltophilia by Antimicrobial Photodynamic Therapy

Irina Buchovec et al.

Summary: Antimicrobial photodynamic therapy (aPDT) based on riboflavin and chlorophyllin can effectively inactivate Acinetobacter baumannii and Stenotrophomonas maltophilia, especially for biofilm bacteria.

MICROORGANISMS (2022)

Article Infectious Diseases

Antimicrobial Photodynamic Therapy Mediated by Fotenticine and Methylene Blue on Planktonic Growth, Biofilms, and Burn Infections of Acinetobacter baumannii

Livia M. A. Figueiredo-Godoi et al.

Summary: This study evaluated the efficacy of a new photosensitizer derivative called Fotoenticine-FTC in antimicrobial photodynamic therapy (aPDT) against Acinetobacter baumannii. The results showed that methylene blue (MB) had greater antimicrobial activity compared to FTC, inhibiting the growth of bacterial cells in planktonic cultures, biofilms, and burn infections in Galleria mellonella.

ANTIBIOTICS-BASEL (2022)

Article Biotechnology & Applied Microbiology

Charge effect of water-soluble porphyrin derivatives as a prototype to fight infections caused by Acinetobacter baumannii by aPDT approaches

Carolina da Silva Canielles Caprara et al.

Summary: In this study, the antimicrobial photodynamic activity of two porphyrin compounds against A. Baumannii was evaluated. The cationic derivative H2TMePyP+ showed higher antimicrobial activity and anti-biofilm activity, as well as increased effectiveness of two common antibiotics.

BIOFOULING (2022)

Article Multidisciplinary Sciences

Efficacy of violet-blue light to inactive microbial growth

Davide Amodeo et al.

Summary: This study evaluated the efficacy of violet-blue light at 405 nm (VBL405) in inhibiting microbial growth on surfaces and in the air. The results showed that VBL405 had the strongest inhibitory effect on microbial growth, especially at a distance of 2 meters from the light source. Additionally, the average microbial reduction in the sampled air after exposure to VBL405 was approximately 70%.

SCIENTIFIC REPORTS (2022)

Article Oncology

Antibacterial effect of singlet oxygen depending on bacteria surface charge

Il Kwon Bae et al.

Summary: We investigated the bactericidal effects of two types of photoinduced reactive oxygen species (ROS) on bacteria with distinct surface charges. The results showed that one type of ROS was significantly dependent on the surface charge of the bacteria, which could be significant in enhancing treatment efficiency in the clinical field.

PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY (2022)

Review Microbiology

Treatment of Pseudomonas aeruginosa infectious biofilms: Challenges and strategies

Rui Yin et al.

Summary: Pseudomonas aeruginosa, a major pathogen in human infections, forms biofilms due to the secretion of extracellular polymeric substances, leading to antibiotic resistance. New treatment technologies, such as antimicrobial peptides and bacteriophage therapy, have been developed to target P. aeruginosa biofilms.

FRONTIERS IN MICROBIOLOGY (2022)

Article Biochemistry & Molecular Biology

Combined Antimicrobial Blue Light and Antibiotics as a Tool for Eradication of Multidrug-Resistant Isolates of Pseudomonas aeruginosa and Staphylococcus aureus: In Vitro and In Vivo Studies

Agata Wozniak et al.

Summary: This study confirmed the effectiveness of antimicrobial blue light in combination with antibiotics against multidrug-resistant Pseudomonas aeruginosa and Staphylococcus aureus, with in vivo experiments demonstrating synergy between the two treatments.

ANTIOXIDANTS (2022)

Review Microbiology

The Emergence of the Genus Comamonas as Important Opportunistic Pathogens

Michael P. Ryan et al.

Summary: Comamonas spp. are non-fermenting Gram-negative bacilli that are commonly found in soil, water sources, and animal intestines. While they are primarily associated with environmental bioremediation, they can cause infections in humans. Treatment of infections associated with Comamonas species is generally not difficult, but antibiotic resistance is a concern. Therefore, it is important to include these pathogens in hospital screening programs.

PATHOGENS (2022)

Article Biochemistry & Molecular Biology

Searching for antimicrobial photosensitizers among a panel of BODIPYs

Viviana Teresa Orlandi et al.

Summary: Antimicrobial Photodynamic Therapy (aPDT) has gained attention for inhibiting microbial growth and spread. Boron-dipyrromethenes (BODIPYs) are promising photosensitizers for antimicrobial applications. This study found that neutral BODIPYs can effectively photoinactivate Staphylococcus aureus, Pseudomonas aeruginosa, and Candida albicans. One neutral compound (B9) showed the best photoinactivation of P. aeruginosa. Additionally, the compounds successfully inhibited biofilms of the three model microorganisms, with better results for S. aureus and P. aeruginosa.

PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES (2022)

Article Chemistry, Physical

Advances in photodynamic antimicrobial chemotherapy

Abdulaziz Anas et al.

Summary: PACT, utilizing light and photosensitizers, has advanced significantly in treating microbial infections, competing with antibiotics and reducing antibiotic resistance. New light sources, photosensitizers, and applications are constantly evolving, including COVID-19 treatment and disinfection of food and water. PACT demonstrates good pathogen selectivity and treatment efficiency.

JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY C-PHOTOCHEMISTRY REVIEWS (2021)

Article Microbiology

Eradication of Acinetobacter baumannii Planktonic and Biofilm Cells Through Erythrosine-Mediated Photodynamic Inactivation Augmented by Acetic Acid and Chitosan

Zahra Fekrirad et al.

Summary: Photodynamic inactivation (PDI) is an effective treatment for multidrug-resistant bacterial infections, with anionic photosensitizers like erythrosine B showing enhanced efficacy when combined with acetic acid and chitosan. The study demonstrated that PDI using erythrosine B in acetic acid effectively eliminated A.baumannii planktonic cells and chitosan enhanced the anti-biofilm efficacy of PDI, suggesting potential for combination therapy targeting biofilms.

CURRENT MICROBIOLOGY (2021)

Article Infectious Diseases

Legionella antibiotic susceptibility testing: is it time for international standardization and evidence-based guidance?

Edward Portal et al.

Summary: This paper presents recommendations for the standardization of antimicrobial susceptibility testing methods, guidelines, and reference strains for Legionnaire's disease, aiming to facilitate a more improved era of antibiotic resistance determination.

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY (2021)

Review Biochemistry & Molecular Biology

Photodynamic disinfection and its role in controlling infectious diseases

Rafael T. Aroso et al.

Summary: Photodynamic therapy is gaining attention as a response to the shortage of new antibiotics and the increase in drug resistant infections, with a focus on the efficacy of photosensitizers and affordability of light sources to expand applications in managing infectious diseases. Success in the management of infectious diseases using photodynamic therapy will depend on the effectiveness of photosensitizers and availability of efficient treatments.

PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES (2021)

Review Environmental Sciences

UVC-based photoinactivation as an efficient tool to control the transmission of coronaviruses

Sanjeev K. Bhardwaj et al.

Summary: The COVID-19 pandemic has highlighted the importance of environmental disinfection, with UVC light showing great potential in germicidal disinfection of various microbes. This method can be effective in preventing and controlling infections and transmission, and is applicable in healthcare and public spaces.

SCIENCE OF THE TOTAL ENVIRONMENT (2021)

Review Biotechnology & Applied Microbiology

Acinetobacter spp. in food and drinking water - A review

Ana Carvalheira et al.

Summary: Acinetobacter spp. has emerged as a major public health concern due to their increased resistance to antibiotics and association with various infections. Food has been identified as a potential source of dissemination of Acinetobacter spp., emphasizing the need for further research on their potential health risks as foodborne pathogens.

FOOD MICROBIOLOGY (2021)

Article Infectious Diseases

Development of a high-level light-activated disinfectant for hard surfaces and medical devices

Matthew P. Wylie et al.

Summary: Light-activated photosensitizer solutions in the presence of surfactants and germination-promoting agents provide a highly effective method to eradicate dormant and vegetative bacteria. These solutions could provide a useful alternative to traditional chemical agents used for high-level decontamination and infection control within health care.

INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS (2021)

Editorial Material Biochemistry & Molecular Biology

Legionela pneumophila

Ines G. Goncalves et al.

TRENDS IN MICROBIOLOGY (2021)

Review Chemistry, Multidisciplinary

Causes, Factors, and Control Measures of Opportunistic Premise Plumbing Pathogens-A Critical Review

Erin Leslie et al.

Summary: This review critically analyzes the chemical and physical parameters that influence the occurrence of opportunistic pathogens in the drinking water distribution system, specifically in premise plumbing. Factors such as water age, disinfectant residual, temperature, pH, and pipe materials are found to significantly impact the presence of opportunistic pathogens. The study proposes a focus on common features identified in the literature to reduce or eliminate the incidence of these pathogens.

APPLIED SCIENCES-BASEL (2021)

Article Microbiology

Occurrence of Legionella spp. in Man-Made Water Sources: Isolates Distribution and Phylogenetic Characterization in the Emilia-Romagna Region

Marta Mazzotta et al.

Summary: The study in the Emilia-Romagna region of Italy revealed a higher prevalence of non-Legionella pneumophila species in hospital and community environments compared to L. pneumophila, with a higher frequency of non-L. pneumophila species in both environments. The analysis also showed significant differences in Legionella distribution between hospital and community environments, with a significant abundance of L. pneumophila in hospitals compared to communities. The findings suggest the importance of Legionella surveillance in both hospital and community settings, particularly focusing on non-L. pneumophila species less associated with human disease.

PATHOGENS (2021)

Review Food Science & Technology

Emerging trends in the photodynamic inactivation (PDI) applied to the food decontamination

Marco Cossu et al.

Summary: The food and drink manufacturing industry is looking for alternative sanitation systems that can achieve antimicrobial efficiency while saving energy and water resources. The use of photodynamic inactivation (PDI) technology, which combines light with photosensitisers to combat microbial agents, shows promise in reducing microbial load in food processing and extending food shelf-life. Recent developments in PDI systems, including the use of LED lamps and exogenous PS from plant sources, offer potential advancements in effective disinfection systems for the food industry.

FOOD RESEARCH INTERNATIONAL (2021)

Article Biochemistry & Molecular Biology

Photodynamic Inactivation of Legionella pneumophila Biofilm Formation by Cationic Tetra- and Tripyridylporphyrins in Waters of Different Hardness

Martina Muskovic et al.

Summary: Three cationic tripyridylporphyrins showed different stability and singlet oxygen production in waters of varying hardness, but all demonstrated effectiveness against L. pneumophila adhesion, biofilm formation, and destruction in micromolar concentrations. However, higher water hardness generally decreased the PDI activity of all porphyrins at different biofilm growth stages.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

Article Biochemistry & Molecular Biology

Photoinactivation of Pseudomonas aeruginosa Biofilm by Dicationic Diaryl-Porphyrin

Viviana Teresa Orlandi et al.

Summary: Antimicrobial photodynamic therapy (aPDT) is gaining attention as a promising tool for treating microbial infections and sanitizing environments. A study on a panel of photosensitizers found that dicationic diaryl-porphyrins show potential in efficiently photoinactivating Pseudomonas aeruginosa, including inhibiting biofilm formation. These findings suggest the potential applicability of dicationic diaryl-porphyrins in different fields for combating difficult-to-treat microbes like P. aeruginosa.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

Article Multidisciplinary Sciences

Interplay of phosphate and carbonate ions with flavin photosensitizers in photodynamic inactivation of bacteria

Daniel Bernhard Eckl et al.

Summary: The study investigated the impact of carbonate and phosphate ions on the photodynamic inactivation of pathogenic bacteria using cationic flavins. Results showed that at low ion concentrations, both Staphylococcus aureus and Pseudomonas aeruginosa could be easily inactivated by at least one photosensitizer, with reductions in cell counts of up to 6 log(10) steps. However, the efficacy of inactivation decreased somewhat at medium ion concentrations and reached almost zero at high ion concentrations. The presence of carbonate and phosphate ions may reduce the efficiency of PDI by attacking the photosensitizer molecule, but efficient reduction of bacterial cells is still achievable within certain concentrations.

PLOS ONE (2021)

Article Chemistry, Medicinal

Nanoparticulate β-Cyclodextrin with Gallium Tetraphenylporphyrin Demonstrates in Vitro and in Vivo Antimicrobial Efficacy against Mycobacteroides abscessus and Mycobacterium avium

Seoung-Ryoung Choi et al.

Summary: The study synthesized a new antimicrobial nanoparticle CDGaTP, showing sustained drug release for 15 days and synergistic activity with transferrin or lactoferrin against drug-resistant pathogens. The nanoparticle demonstrated activity against NTM pathogens through inhibition of antioxidant enzymes and generated reactive oxygen species.

ACS INFECTIOUS DISEASES (2021)

Article Microbiology

Inactivation Effect of Violet and Blue Light on ESKAPE Pathogens and Closely Related Non-pathogenic Bacterial Species - A Promising Tool Against Antibiotic-Sensitive and Antibiotic-Resistant Microorganisms

Katharina Hoenes et al.

Summary: The use of visible light to inactivate ESKAPE pathogens shows promise as a treatment method, with different bacterial species showing varying levels of sensitivity to the light. Overall, non-pathogenic bacteria are less susceptible to inactivation compared to their pathogenic counterparts.

FRONTIERS IN MICROBIOLOGY (2021)

Article Immunology

Quinine Enhances Photo-Inactivation of Gram-Negative Bacteria

Leon G. Leanse et al.

JOURNAL OF INFECTIOUS DISEASES (2020)

Review Pharmacology & Pharmacy

Naegleria fowleri: Sources of infection, pathophysiology, diagnosis, and management; a review

Muhammad Jahangeer et al.

CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY (2020)

Article Agriculture, Dairy & Animal Science

Inactivation of milk-borne pathogens by blue light exposure

C. dos Anjos et al.

JOURNAL OF DAIRY SCIENCE (2020)

Review Microbiology

An Update on the Genus Aeromonas: Taxonomy, Epidemiology, and Pathogenicity

Ana Fernandez-Bravo et al.

MICROORGANISMS (2020)

Article Microbiology

Methylobacterium spp. as Emerging Opportunistic Premise Plumbing Pathogens

Kyle J. Szwetkowski et al.

PATHOGENS (2020)

Article Microbiology

The in vitro Photoinactivation of Helicobacter pylori by a Novel LED-Based Device

Paola Morici et al.

FRONTIERS IN MICROBIOLOGY (2020)

Review Microbiology

Bacterial Quorum Sensing During Infection

Sheyda Azimi et al.

ANNUAL REVIEW OF MICROBIOLOGY, VOL 74, 2020 (2020)

Article Pharmacology & Pharmacy

Photodynamic inactivation mediated by 5-aminolevulinic acid of bacteria in planktonic and biofilm forms

Gabriela Cervini Bohm et al.

BIOCHEMICAL PHARMACOLOGY (2020)

Article Biochemistry & Molecular Biology

Cationic Porphyrins as Effective Agents in Photodynamic Inactivation of Opportunistic Plumbing PathogenLegionella pneumophila

Andrija Lesar et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)

Article Public, Environmental & Occupational Health

Outbreak ofRalstonia mannitolilyticabacteraemia in patients undergoing haemodialysis at a tertiary hospital in Pretoria, South Africa

Mohamed Said et al.

ANTIMICROBIAL RESISTANCE AND INFECTION CONTROL (2020)

Article Biochemistry & Molecular Biology

Global priority multidrug-resistant pathogens do not resist photodynamic therapy

Caetano Padial Sabino et al.

JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY (2020)

Article Materials Science, Biomaterials

A cost-effective combination of Rose Bengal and off-the-shelf cationic polystyrene for the photodynamic inactivation of Pseudomonas aeruginosa

Carla Arnau del Valle et al.

MATERIALS SCIENCE AND ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2020)

Review Microbiology

The Genus Ochrobactrum as Major Opportunistic Pathogens

Michael P. Ryan et al.

MICROORGANISMS (2020)

Article Engineering, Chemical

Impact of UV irradiation at full scale on bacterial communities in drinking water

Kristjan Pullerits et al.

NPJ CLEAN WATER (2020)

Review Biochemical Research Methods

Nontuberculous mycobacteria in drinking water systems - the challenges of characterization and risk mitigation

Katherine Dowdell et al.

CURRENT OPINION IN BIOTECHNOLOGY (2019)

Editorial Material Parasitology

Naegleria fowleri

Jose E. Pinero et al.

TRENDS IN PARASITOLOGY (2019)

Article Biotechnology & Applied Microbiology

Violet-Blue Light Arrays at 405 Nanometers Exert Enhanced Antimicrobial Activity for Photodisinfection of Monomicrobial Nosocomial Biofilms

F. D. Halstead et al.

APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2019)

Article Biotechnology & Applied Microbiology

Photoinactivation of dormant Mycobacterium smegmatis due to its endogenous porphyrins

Margarita O. Shleeva et al.

APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2019)

Article Biochemistry & Molecular Biology

Hydrogen Peroxide Enhances the Antibacterial Effect of Methylene Blue-based Photodynamic Therapy on Biofilm-forming Bacteria

Seung Mok Yang et al.

PHOTOCHEMISTRY AND PHOTOBIOLOGY (2019)

Review Immunology

Mycobacterium avium: an overview

Caroline Busatto et al.

TUBERCULOSIS (2019)

Article Biochemistry & Molecular Biology

Blue light irradiation triggers the antimicrobial potential of ZnO nanoparticles on drug-resistant Acinetobacter baumannii

Ming-Yeh Yang et al.

JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY (2018)

Article Ecology

Vermamoeba vermiformis: a Free-Living Amoeba of Interest

Vincent Delafont et al.

MICROBIAL ECOLOGY (2018)

Article Oncology

Catalase A is involved in the response to photooxidative stress in Pseudomonas aeruginosa

Viviana Teresa Orlandi et al.

PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY (2018)

Review Immunology

Brevundimonas spp: Emerging global opportunistic pathogens

Michael P. Ryan et al.

VIRULENCE (2018)

Review Biology

Acinetobacter spp. as nosocomial pathogens: Epidemiology and resistance features

Saad B. Almasaudi

SAUDI JOURNAL OF BIOLOGICAL SCIENCES (2018)

Article Engineering, Environmental

Chlorine dioxide inactivation of Pseudomonas aeruginosa and Staphylococcus aureus in water: The kinetics and mechanism

Isaac Ofori et al.

JOURNAL OF WATER PROCESS ENGINEERING (2018)

Article Immunology

Elizabethkingia anophelis and Association with Tap Water and Handwashing, Singapore

Chee-Fu Yung et al.

EMERGING INFECTIOUS DISEASES (2018)

Review Radiology, Nuclear Medicine & Medical Imaging

The Effect of Quorum-Sensing and Efflux Pumps Interactions in Pseudomonas aeruginosa Against Photooxidative Stress

Parizad Rezaie et al.

JOURNAL OF LASERS IN MEDICAL SCIENCES (2018)

Article Biochemistry & Molecular Biology

Spectroscopic characterization and fluorescence imaging of Helicobacter pylori endogenous porphyrins

Antonella Battisti et al.

BIOPHYSICAL CHEMISTRY (2017)

Review Pharmacology & Pharmacy

Antimicrobial blue light inactivation of pathogenic microbes: State of the art

Yucheng Wang et al.

DRUG RESISTANCE UPDATES (2017)

Article Biotechnology & Applied Microbiology

Antibacterial Activity of Blue Light against Nosocomial Wound Pathogens Growing Planktonically and as Mature Biofilms

Fenella D. Halstead et al.

APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2016)

Article Environmental Sciences

Point-of-use water disinfection using ultraviolet and visible light-emitting diodes

Gough Yumu Lui et al.

SCIENCE OF THE TOTAL ENVIRONMENT (2016)

Review Microbiology

Pseudomonas aeruginosa in premise plumbing of large buildings

Emilie Bedard et al.

MICROBIOLOGYOPEN (2016)

Article Chemistry, Multidisciplinary

Photosensitizer-Embedded Polyacrylonitrile Nanofibers as Antimicrobial Non-Woven Textile

Sarah L. Stanley et al.

NANOMATERIALS (2016)

Article Medicine, Research & Experimental

Photodynamic Inactivation of Bacteria In Vitro Under the Effect of Blue Light

E. S. Keshishyan et al.

BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE (2015)

Article Engineering, Environmental

UV Disinfection Induces a Vbnc State in Escherichia coli and Pseudomonas aeruginosa

Shenghua Zhang et al.

ENVIRONMENTAL SCIENCE & TECHNOLOGY (2015)

Review Chemistry, Physical

Water-Solubilization of P(V) and Sb(V) Porphyrins and Their Photobiological Application

Jin Matsumoto et al.

INTERNATIONAL JOURNAL OF PHOTOENERGY (2015)

Article Biochemistry & Molecular Biology

Immobilized photosensitizers for antimicrobial applications

Cinzia Spagnul et al.

JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY (2015)

Review Chemistry, Physical

Potential applications of porphyrins in photodynamic inactivation beyond the medical scope

Eliana Alves et al.

JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY C-PHOTOCHEMISTRY REVIEWS (2015)

Review Biochemistry & Molecular Biology

Resistance in antimicrobial photodynamic inactivation of bacteria

Tim Maisch

PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES (2015)

Article Chemistry, Multidisciplinary

Photodynamic water disinfection

N. A. Kuznetsova et al.

RUSSIAN JOURNAL OF GENERAL CHEMISTRY (2015)

Review Environmental Sciences

Common Features of Opportunistic Premise Plumbing Pathogens

Joseph O. Falkinham

INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH (2015)

Article Biotechnology & Applied Microbiology

Structure and microbial diversity of biofilms on different pipe materials of a model drinking water distribution systems

Agnieszka Rozej et al.

WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY (2015)

Article Microbiology

Recovery of Pseudomonas aeruginosa culturability following copper- and chlorine-induced stress

Emilie Bedard et al.

FEMS MICROBIOLOGY LETTERS (2014)

Review Microbiology

Methylobacterium and Its Role in Health Care-Associated Infection

Julia Kovaleva et al.

JOURNAL OF CLINICAL MICROBIOLOGY (2014)

Article Biochemistry & Molecular Biology

Photodynamic inactivation of multidrug-resistant bacteria in hospital wastewaters: influence of residual antibiotics

Joana Almeida et al.

PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES (2014)

Article Biochemistry & Molecular Biology

Photodynamic Inactivation of Bacterial and Yeast Biofilms With a Cationic Porphyrin

Sandra Beirao et al.

PHOTOCHEMISTRY AND PHOTOBIOLOGY (2014)

Article Engineering, Environmental

Anticipating Challenges with In-Building Disinfection for Control of Opportunistic Pathogens

William J. Rhoads et al.

WATER ENVIRONMENT RESEARCH (2014)

Review Microbiology

Antimicrobial photodynamic therapy for inactivation of biofilms formed by oral key pathogens

Fabian Cieplik et al.

FRONTIERS IN MICROBIOLOGY (2014)

Article Pharmacology & Pharmacy

Light based anti-infectives: ultraviolet C irradiation, photodynamic therapy, blue light, and beyond

Rui Yin et al.

CURRENT OPINION IN PHARMACOLOGY (2013)

Review Infectious Diseases

Clinical relevance of the ESKAPE pathogens

Jack N. Pendleton et al.

EXPERT REVIEW OF ANTI-INFECTIVE THERAPY (2013)

Article Biochemistry & Molecular Biology

Photodynamic biofilm inactivation by SAPYR-An exclusive singlet oxygen photosensitizer

Fabian Cieplik et al.

FREE RADICAL BIOLOGY AND MEDICINE (2013)

Review Food Science & Technology

Antibacterial Photosensitization-Based Treatment for Food Safety

Zivile Luksiene et al.

FOOD ENGINEERING REVIEWS (2013)

Article Biochemistry & Molecular Biology

Comparative photodynamic inactivation of antibiotic resistant bacteria by first and second generation cationic photosensitizers

Dora C. S. Costa et al.

PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES (2012)

Article Biochemistry & Molecular Biology

Effect of Organic Matter on the In Vitro Photoeradication of Pseudomonas aeruginosa by Means of a Cationic Tetraaryl-porphyrin

Viviana T. Orlandi et al.

PHOTOCHEMISTRY AND PHOTOBIOLOGY (2012)

Article Biochemistry & Molecular Biology

Antimicrobial Photodynamic Therapy on Drug-resistant Pseudomonas aeruginosa-induced Infection. An In Vivo Study

Maria C. E. Hashimoto et al.

PHOTOCHEMISTRY AND PHOTOBIOLOGY (2012)

Article Toxicology

Photodynamic Inactivation of Microbial Pathogens: Disinfection of Water and Prevention of Water-Borne Diseases

Giulio Jori et al.

JOURNAL OF ENVIRONMENTAL PATHOLOGY TOXICOLOGY AND ONCOLOGY (2011)

Article Biotechnology & Applied Microbiology

Effects of Diverse Water Pipe Materials on Bacterial Communities and Water Quality in the Annular Reactor

Hyun-Jung Jang et al.

JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY (2011)

Review Medicine, General & Internal

Multidrug-Resistant Acinetobacter spp.: Increasingly Problematic Nosocomial Pathogens

Kyungwon Lee et al.

YONSEI MEDICAL JOURNAL (2011)

Article Engineering, Environmental

Biofilm formation on materials commonly used in household drinking water systems

A. A. Morvay et al.

WATER SCIENCE AND TECHNOLOGY-WATER SUPPLY (2011)

Article Ophthalmology

Effects of Photodynamic Therapy on Rapidly Growing Nontuberculous Mycobacteria Keratitis

Min-Hsiu Shih et al.

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2011)

Article Microbiology

The Effect of a Cationic Porphyrin on Pseudomonas aeruginosa Biofilms

Tracy L. Collins et al.

CURRENT MICROBIOLOGY (2010)

Article Public, Environmental & Occupational Health

Resistance of Legionella pneumophila serotype 1 biofilms to chlorine-based disinfection

I. R. Cooper et al.

JOURNAL OF HOSPITAL INFECTION (2010)

Review Public, Environmental & Occupational Health

Sphingomonas paucimobilis: a persistent Gram-negative nosocomial infectious organism

M. P. Ryan et al.

JOURNAL OF HOSPITAL INFECTION (2010)

Article Biochemistry & Molecular Biology

Enhanced Bactericidal Activity of Modified Titania in Sunlight against Pseudomonas aeruginosa, a Water-Borne Pathogen

S. Swetha et al.

PHOTOCHEMISTRY AND PHOTOBIOLOGY (2010)

Article Biochemistry & Molecular Biology

In Vitro Photodynamic Eradication of Pseudomonas aeruginosa in Planktonic and Biofilm Culture

Cale N. Street et al.

PHOTOCHEMISTRY AND PHOTOBIOLOGY (2009)

Review Microbiology

Antifungal photodynamic therapy

Ryan F. Donnelly et al.

MICROBIOLOGICAL RESEARCH (2008)

Article Microbiology

Acanthamoeba polyphaga resuscitates viable non-culturable Legionella pneumophila after disinfection

Maria Teresa Garcia et al.

ENVIRONMENTAL MICROBIOLOGY (2007)

Article Engineering, Environmental

Survival of Mycobacterium avium in a model distribution system

CD Norton et al.

WATER RESEARCH (2004)

Article Biochemistry & Molecular Biology

δ-Aminolaevulinic acid mediated photodynamic antimicrobial chemotherapy on Pseudomonas aeruginosa planktonic and biofilm cultures

CF Lee et al.

JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY (2004)

Article Biotechnology & Applied Microbiology

Photosensitising agents - circumventing resistance and breaking down biofilms: a review

M Wainwright et al.

INTERNATIONAL BIODETERIORATION & BIODEGRADATION (2004)

Article Biochemistry & Molecular Biology

Antibacterial photodynamic therapy in dermatology

Tim Maisch et al.

PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES (2004)

Review Immunology

Biofilms: Microbial life on surfaces

RM Donlan

EMERGING INFECTIOUS DISEASES (2002)

Article Public, Environmental & Occupational Health

Capability of mucoid Pseudomonas aeruginosa to survive in chlorinated water

S Grobe et al.

INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH (2001)