Related references
Note: Only part of the references are listed.Water-soluble chitosan eases development of mucoadhesive buccal films and wafers for children
Karin Korelc et al.
INTERNATIONAL JOURNAL OF PHARMACEUTICS (2023)
Pluronic® triblock copolymer-based nanoformulations for cancer therapy: A 10-year overview
Karine Cappuccio de Castro et al.
JOURNAL OF CONTROLLED RELEASE (2023)
RNA and nanocarriers: next generation drug and delivery platform take center stage
Jessica Rouge
TRENDS IN BIOTECHNOLOGY (2023)
Antibacterial and cytotoxicity assessment of poly (N-vinyl imidazole)/nitrogen-doped graphene quantum dot nanocomposite hydrogels
Solmaz Massoudi et al.
POLYMER BULLETIN (2023)
Lactoferrin as a Component of Pharmaceutical Preparations: An Experimental Focus
Fabiola Guzman-Mejia et al.
PHARMACEUTICALS (2023)
Evaluation of pediatric patients with suspected polyethylene glycol and polysorbate allergy before mRNA SARS-CoV2 vaccination
Betul Gemici Karaaslan et al.
ALLERGOLOGIA ET IMMUNOPATHOLOGIA (2023)
A pipeline analysis of advanced therapy medicinal products
Georgina C. Wilkins et al.
DRUG DISCOVERY TODAY (2023)
I-ACT for Children: helping close the gap in drug approval for adults and children
Max J. Coppes et al.
PEDIATRIC RESEARCH (2023)
Safety of mRNA vaccination for COVID-19 in children with polyethylene glycol (PEG)-asparaginase allergy
Rebecca Doyle et al.
PEDIATRIC ALLERGY AND IMMUNOLOGY (2023)
Chitosan-Based Polymer Blends for Drug Delivery Systems
Malkiet Kaur et al.
POLYMERS (2023)
Design, Evaluation and Comparison of Nanostructured Lipid Carriers and Chitosan Nanoparticles as Carriers of Poorly Soluble Drugs to Develop Oral Liquid Formulations Suitable for Pediatric Use
Giulia Nerli et al.
PHARMACEUTICS (2023)
Exploring the Potential of Nanotechnology in Pediatric Healthcare: Advances, Challenges, and Future Directions
Hossein Omidian et al.
PHARMACEUTICS (2023)
Approved Nanomedicine against Diseases
Yuanchao Jia et al.
PHARMACEUTICS (2023)
Chitosan: A Potential Biopolymer in Drug Delivery and Biomedical Applications
Nimeet Desai et al.
PHARMACEUTICS (2023)
Patient-centric drug product development: Acceptability across patient populations-Science and evidence
Sven Stegemann et al.
EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS (2023)
Regenerative medicine: current research and perspective in pediatric surgery
Koichi Deguchi et al.
PEDIATRIC SURGERY INTERNATIONAL (2023)
Synthetic biology-inspired cell engineering in diagnosis, treatment, and drug development
Ninglin Zhao et al.
SIGNAL TRANSDUCTION AND TARGETED THERAPY (2023)
CRISPR/Cas9 therapeutics: progress and prospects
Tianxiang Li et al.
SIGNAL TRANSDUCTION AND TARGETED THERAPY (2023)
Review of paediatric gastrointestinal physiology relevant to the absorption of orally administered medicines
Erik Wollmer et al.
ADVANCED DRUG DELIVERY REVIEWS (2022)
Analysis of clinical trials on biomaterial and therapeutic applications of chitosan: A review
Maithili N. Kantak et al.
CARBOHYDRATE POLYMERS (2022)
Osteosarcoma from the unknown to the use of exosomes as a versatile and dynamic therapeutic approach
Ana Santos et al.
EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS (2022)
New challenges in the use of nanomedicine in cancer therapy
Mahmood Rasool et al.
BIOENGINEERED (2022)
Adoptive Cell Therapy in Pediatric and Young Adult Solid Tumors: Current Status and Future Directions
John A. Ligon et al.
FRONTIERS IN IMMUNOLOGY (2022)
A Stepwise Framework for the Systematic Development of Lipid Nanoparticles
Joao Basso et al.
BIOMOLECULES (2022)
Advanced Therapy Medicinal Products' Translation in Europe: A Developers' Perspective
Maja Pizevska et al.
FRONTIERS IN MEDICINE (2022)
Nanoparticles for Diagnosis and Target Therapy in Pediatric Brain Cancers
Clara Guido et al.
DIAGNOSTICS (2022)
Innovative, Sugar-Free Oral Hydrogel as a Co-administrative Vehicle for Pediatrics: a Strategy to Enhance Patient Compliance
Margarida Pereira et al.
AAPS PHARMSCITECH (2022)
ACCELERATE-Five years accelerating cancer drug development for children and adolescents
Andrew D. J. Pearson et al.
EUROPEAN JOURNAL OF CANCER (2022)
Paediatric specific dosage forms: Patient and formulation considerations
Dilawar Khan et al.
INTERNATIONAL JOURNAL OF PHARMACEUTICS (2022)
Improving clinical paediatric research and learning from COVID-19: recommendations by the Conect4Children expert advice group
Athimalaipet Ramanan et al.
PEDIATRIC RESEARCH (2022)
Engineering the next generation of cell-based therapeutics
Caleb J. Bashor et al.
NATURE REVIEWS DRUG DISCOVERY (2022)
Understanding caregiver acceptance of screening for family substance use in pediatric clinics serving economically disadvantaged children
Pamela A. Matson et al.
SUBSTANCE ABUSE (2022)
Nanotechnology-Based Diagnostic and Therapeutic Strategies for Neuroblastoma
Hui Yan et al.
FRONTIERS IN PHARMACOLOGY (2022)
Development of CAR T Cell Therapy in Children-A Comprehensive Overview
Michael Boettcher et al.
JOURNAL OF CLINICAL MEDICINE (2022)
Catching Them Early: Framework Parameters and Progress for Prenatal and Childhood Application of Advanced Therapies
Carsten W. Lederer et al.
PHARMACEUTICS (2022)
Controlled temperature-mediated curcumin release from magneto-thermal nanocarriers to kill bone tumors
A. Khodaei et al.
BIOACTIVE MATERIALS (2022)
Formulation Challenges and Strategies to Develop Pediatric Dosage Forms
Wedad A. Malkawi et al.
CHILDREN-BASEL (2022)
Pharmacomicrobiomics in Pediatric Oncology: The Complex Interplay between Commonly Used Drugs and Gut Microbiome
Davide Leardini et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2022)
Where Is Nano Today and Where Is It Headed? A Review of Nanomedicine and the Dilemma of Nanotoxicology
Catia Domingues et al.
ACS NANO (2022)
Administration of oral dosage forms of medicines to children in a resource limited setting
Abarna Nadeshkumar et al.
PLOS ONE (2022)
Lipid nanoparticles in the development of mRNA vaccines for COVID-19
Barnabas Wilson et al.
JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY (2022)
Clinical trials of stem cell-based therapies for pediatric diseases: a comprehensive analysis of trials registered on ClinicalTrials.gov and the ICTRP portal site
Yinwen Ji et al.
STEM CELL RESEARCH & THERAPY (2022)
Recommendations on Off-Label Drug Use in Pediatric Guidelines
Min Meng et al.
FRONTIERS IN PHARMACOLOGY (2022)
The Past, Present, and Future of Non-Viral CAR T Cells
Alex Moretti et al.
FRONTIERS IN IMMUNOLOGY (2022)
New Advances in Biomedical Application of Polymeric Micelles
Ana Figueiras et al.
PHARMACEUTICS (2022)
Recent Advances of Chitosan Formulations in Biomedical Applications
Mohammed A. S. Abourehab et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2022)
Nanotechnology for the treatment of paediatric diseases: A review
Morgana Souza Marques et al.
JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY (2022)
Potential solutions for manufacture of CAR T cells in cancer immunotherapy
Ulrich Blache et al.
NATURE COMMUNICATIONS (2022)
Tackling Dyslipidemia in Obesity from a Nanotechnology Perspective
Laura M. Trandafir et al.
NUTRIENTS (2022)
Lactoferrin-Conjugated Nanoparticles as New Antivirals
Malgorzata Krzyzowska et al.
PHARMACEUTICS (2022)
Hyperbranched-star PEI-g-PEG as a nonviral vector with efficient uptake and hypotoxicity for retinoblastoma gene therapy application
Jiahao Wang et al.
COLLOID AND INTERFACE SCIENCE COMMUNICATIONS (2022)
Lipid Nanoparticles as Delivery Vehicles for Inhaled Therapeutics
Ellenmae W. X. Leong et al.
BIOMEDICINES (2022)
Overcoming Challenges in Pediatric Formulation with a Patient-Centric Design Approach: A Proof-of-Concept Study on the Design of an Oral Solution of a Bitter Drug
John Dike N. Ogbonna et al.
PHARMACEUTICALS (2022)
Nanotechnology for Pediatric Retinoblastoma Therapy
Eleonora Russo et al.
PHARMACEUTICALS (2022)
Administration of medicines to children: a practical guide
Lucinda Smith et al.
AUSTRALIAN PRESCRIBER (2022)
Safety and Toxicity Implications of Multifunctional Drug Delivery Nanocarriers on Reproductive Systems In Vitro and In Vivo
Anas Ahmad
FRONTIERS IN TOXICOLOGY (2022)
Pediatric Pharmacokinetics and Dose Predictions: A Report of a Satellite Meeting to the 10th Juvenile Toxicity Symposium
Bianca D. van Groen et al.
CTS-CLINICAL AND TRANSLATIONAL SCIENCE (2021)
A best practice framework for applying physiologically-based pharmacokinetic modeling to pediatric drug development
Trevor N. Johnson et al.
CPT-PHARMACOMETRICS & SYSTEMS PHARMACOLOGY (2021)
Nanomedicine to fight infectious disease
Kathryn M. Rubey et al.
ADVANCED DRUG DELIVERY REVIEWS (2021)
Adherence to treatment in paediatric patients - results of the nationwide survey in Poland
Przemyslaw Kardas et al.
BMC PEDIATRICS (2021)
A Single-Arm, Open-Label Phase 2 Pilot Study of Vyxeos (CPX-351) in Adults with Relapsed or Refractory Acute Lymphoblastic Leukemia
Bijal D. Shah et al.
BLOOD (2021)
Best practices for selection of excipients for paediatrics-Workshop reflection
Smita Salunke et al.
EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS (2021)
Potential implications of DMET ontogeny on the disposition of commonly prescribed drugs in neonatal and pediatric intensive care units
Siavosh Naji-Talakar et al.
EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY (2021)
Paediatric Medicines - Regulatory Drivers, Restraints, Opportunities and Challenges
Isa Vieira et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2021)
Engineering precision nanoparticles for drug delivery
Michael J. Mitchell et al.
NATURE REVIEWS DRUG DISCOVERY (2021)
CRISPR-Cas9 Gene Editing for Sickle Cell Disease and β-Thalassemia
H. Frangoul et al.
NEW ENGLAND JOURNAL OF MEDICINE (2021)
Targeted dendrimers for antagonizing the migration and viability of NALM-6 lymphoblastic leukemia cells
Chuda Chittasupho et al.
BIOORGANIC CHEMISTRY (2021)
pH-sensitive chitosan nanoparticles loaded with dolutegravir as milk and food admixture for paediatric anti-HIV therapy
K. Priya Dharshini et al.
CARBOHYDRATE POLYMERS (2021)
Controlled Drug Delivery Systems: Current Status and Future Directions
Shivakalyani Adepu et al.
MOLECULES (2021)
The role and impact of polyethylene glycol on anaphylactic reactions to COVID-19 nano-vaccines
P. Bigini et al.
NATURE NANOTECHNOLOGY (2021)
The Pediatric Workforce: Recent Data Trends, Questions, and Challenges for the Future
Robert J. Vinci
PEDIATRICS (2021)
Polycaprolactone Nanoparticles as Promising Candidates for Nanocarriers in Novel Nanomedicines
Sylwia Lukasiewicz et al.
PHARMACEUTICS (2021)
Advanced Therapy Medicinal Products for the Eye: Definitions and Regulatory Framework
Marina Lopez-Paniagua et al.
PHARMACEUTICS (2021)
Developing standards to support the clinical translation of stem cells
Jiani Cao et al.
STEM CELLS TRANSLATIONAL MEDICINE (2021)
Updated analysis of pediatric clinical studies registered in ClinicalTrials.gov, 2008-2019
Yang Zhong et al.
BMC PEDIATRICS (2021)
Polyethylene glycol (PEG) is a cause of anaphylaxis to the Pfizer/BioNTech mRNA COVID-19 vaccine
Priya Sellaturay et al.
CLINICAL AND EXPERIMENTAL ALLERGY (2021)
Current landscape of clinical development and approval of advanced therapies
Carolina Iglesias-Lopez et al.
MOLECULAR THERAPY-METHODS & CLINICAL DEVELOPMENT (2021)
Cell Therapy: Types, Regulation, and Clinical Benefits
Abed El-Hakim El-Kadiry et al.
FRONTIERS IN MEDICINE (2021)
Strategies for Improving Inhalation Technique in Children: A Narrative Review
Anna Volerman et al.
PATIENT PREFERENCE AND ADHERENCE (2021)
Chemical characterization (LC-MS-ESI), cytotoxic activity and intracellular localization of PAMAM G4 in leukemia cells
R. Flores-Mejia et al.
SCIENTIFIC REPORTS (2021)
Inclusion of Adolescents in Adult Clinical Trials: Report of the Institute for Advanced Clinical Trials for Children's Pediatric Innovation Research Forum
Gary J. Noel et al.
THERAPEUTIC INNOVATION & REGULATORY SCIENCE (2021)
Excipients in the Paediatric Population: A Review
Khadija Rouaz et al.
PHARMACEUTICS (2021)
Polymeric and Lipid Nanoparticles: Which Applications in Pediatrics?
Noelia Nieto Gonzalez et al.
PHARMACEUTICS (2021)
Non-viral Vectors in Gene Therapy: Recent Development, Challenges, and Prospects
Hui Zu et al.
AAPS JOURNAL (2021)
Liposomal Extravasation and Accumulation in Tumors as Studied by Fluorescence Microscopy and Imaging Depend on the Fluorescent Label
Guankui Wang et al.
ACS NANO (2021)
Lipid Nanoparticles-From Liposomes to mRNA Vaccine Delivery, a Landscape of Research Diversity and Advancement
Rumiana Tenchov et al.
ACS NANO (2021)
The Use of Stem Cell-Derived Organoids in Disease Modeling: An Update
Joseph Azar et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)
Predictive Performance of Physiology-Based Pharmacokinetic Dose Estimates for Pediatric Trials: Evaluation With 10 Bayer Small-Molecule Compounds in Children
Ibrahim Ince et al.
JOURNAL OF CLINICAL PHARMACOLOGY (2021)
Rufinamide-Loaded Chitosan Nanoparticles in Xyloglucan-Based Thermoresponsive In Situ Gel for Direct Nose to Brain Delivery
Avantika Dalvi et al.
FRONTIERS IN PHARMACOLOGY (2021)
Early-life gut microbiota and its connection to metabolic health in children: Perspective on ecological drivers and need for quantitative approach
Ching Jian et al.
EBIOMEDICINE (2021)
Nanoparticles in the clinic: An update post COVID-19 vaccines
Aaron C. Anselmo et al.
BIOENGINEERING & TRANSLATIONAL MEDICINE (2021)
The Scarcity of Approved Pediatric High-Risk Medical Devices
Juan C. Espinoza
JAMA NETWORK OPEN (2021)
Carboplatin- and Etoposide-Loaded Lactoferrin Protein Nanoparticles for Targeting Cancer Stem Cells in Retinoblastoma In Vitro
Revu V. L. Narayana et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2021)
Understanding Pediatric Drug Lag Time: Review of Selected Drug Package Inserts
Aviva Beleck et al.
JOURNAL OF THE PEDIATRIC INFECTIOUS DISEASES SOCIETY (2021)
Recent advances in transdermal drug delivery systems: a review
Woo Yeup Jeong et al.
BIOMATERIALS RESEARCH (2021)
Synthesis, characterization and antimicrobial activity applications of grafted copolymer alginate-g-poly(N-vinyl imidazole)
Soliman Mehawed Abdellatif Soliman et al.
RSC ADVANCES (2021)
The Promise and the Hope of Gene Therapy
Eleni Papanikolaou et al.
FRONTIERS IN GENOME EDITING (2021)
Poly(1-vinylimidazole) polyplexes as novel therapeutic gene carriers for lung cancer therapy
Gayathri Kandasamy et al.
BEILSTEIN JOURNAL OF NANOTECHNOLOGY (2020)
Patient Centric Pharmaceutical Drug Product Design-The Impact on Medication Adherence
Enrica Menditto et al.
PHARMACEUTICS (2020)
A Focus Group Study about Oral Drug Administration Practices at Hospital Wards-Aspects to Consider in Drug Development of Age-Appropriate Formulations for Children
Maria Rautamo et al.
PHARMACEUTICS (2020)
Combined Pediatric and Adult Trials Submitted to the US Food and Drug Administration 2012-2018
Irin Tanaudommongkon et al.
CLINICAL PHARMACOLOGY & THERAPEUTICS (2020)
How is the Pharmaceutical Industry Structured to Optimize Pediatric Drug Development? Existing Pediatric Structure Models and Proposed Recommendations for Structural Enhancement
Thomas Severin et al.
THERAPEUTIC INNOVATION & REGULATORY SCIENCE (2020)
Squalenoyl-gemcitabine/edelfosine nanoassemblies: Anticancer activity in pediatric cancer cells and pharmacokinetic profile in mice
C. Rodriguez-Nogales et al.
INTERNATIONAL JOURNAL OF PHARMACEUTICS (2020)
Pluronic-based nanovehicles: Recent advances in anticancer therapeutic applications
Ivana Jarak et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2020)
Ruthenium Dendrimers against Human Lymphoblastic Leukemia 1301 Cells
Sylwia Michlewska et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)
Recent insights on indirect mechanisms in developmental toxicity of nanomaterials
Battuja Batbajar Dugershaw et al.
PARTICLE AND FIBRE TOXICOLOGY (2020)
Hyaluronic acid for the treatment of airway diseases in children: Little evidence for few indications
Maria Di Cicco et al.
PEDIATRIC PULMONOLOGY (2020)
Gap between pediatric and adult approvals of molecular targeted drugs
Satoshi Nishiwaki et al.
SCIENTIFIC REPORTS (2020)
Lactoferrin, a multi-functional glycoprotein: Active therapeutic, drug nanocarrier & targeting ligand
Ahmed O. Elzoghby et al.
BIOMATERIALS (2020)
The rectal route of medicine administration for children: Let's get to the bottom of it!
Sara M. Hanning et al.
EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS (2020)
Lactoferrin, a unique molecule with diverse therapeutical and nanotechnological applications
Sally Sabra et al.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2020)
Age and education as factors associated with medication literacy: a community pharmacy perspective
Javier Plaza-Zamora et al.
BMC GERIATRICS (2020)
Population Pharmacokinetics and Model-Based Dosing Optimization of Teicoplanin in Pediatric Patients
Tao Zhang et al.
FRONTIERS IN PHARMACOLOGY (2020)
Machine learning applications in drug development
Clemence Reda et al.
COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL (2020)
Development and content validation of the Pediatric Oral Medicines Acceptability Questionnaires (P-OMAQ): patient-reported and caregiver-reported outcome measures
Diane M. Turner-Bowker et al.
JOURNAL OF PATIENT-REPORTED OUTCOMES (2020)
Pharmacokinetic-Pharmacodynamic Modeling in Pediatric Drug Development, and the Importance of Standardized Scaling of Clearance
Eva Germovsek et al.
CLINICAL PHARMACOKINETICS (2019)
The Challenges of Pediatric Drug Development
Klaus Rose
CURRENT THERAPEUTIC RESEARCH-CLINICAL AND EXPERIMENTAL (2019)
Monoclonal Antibodies and Fc-Fusion Proteins for Pediatric Use: Dosing, Immunogenicity, and Modeling and Simulation in Data Submitted to the US Food and Drug Administration
Xiaomei I. Liu et al.
JOURNAL OF CLINICAL PHARMACOLOGY (2019)
Inactive ingredients in oral medications
Daniel Reker et al.
SCIENCE TRANSLATIONAL MEDICINE (2019)
Benzalkonium Chlorides: Uses, Regulatory Status, and Microbial Resistance
Beatriz Merchel Piovesan Pereira et al.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2019)
RNAi therapeutic and its innovative biotechnological evolution
Yuhua Weng et al.
BIOTECHNOLOGY ADVANCES (2019)
Integrating Nanotechnology into Cancer Care
Piotr Grodzinski et al.
ACS NANO (2019)
Systematic optimization of cationic surface engineered mucoadhesive vesicles employing Design of Experiment (DoE): A preclinical investigation
Amit Verma et al.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2019)
Making Medicines Baby Size: The Challenges in Bridging the Formulation Gap in Neonatal Medicine
Fiona O'Brien et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)
Clinical and Therapeutic Implications of Cancer Stem Cells
Michael F. Clarke
NEW ENGLAND JOURNAL OF MEDICINE (2019)
Current Applications of Nanoemulsions in Cancer Therapeutics
Elena Sanchez-Lopez et al.
NANOMATERIALS (2019)
EU Regulatory Pathways for ATMPs: Standard, Accelerated and Adaptive Pathways to Marketing Authorisation
Giulia Detela et al.
MOLECULAR THERAPY-METHODS & CLINICAL DEVELOPMENT (2019)
Pharmacokinetics of nanotechnology-based formulations in pediatric populations
Venkata K. Yellepeddi et al.
ADVANCED DRUG DELIVERY REVIEWS (2019)
Predictive Pediatric Modeling and Simulation Using Ontogeny Information
Ibrahim Ince et al.
JOURNAL OF CLINICAL PHARMACOLOGY (2019)
Developmental Pharmacodynamics and Modeling in Pediatric Drug Development
Laurie S. Conklin et al.
JOURNAL OF CLINICAL PHARMACOLOGY (2019)
Regulatory Framework for Advanced Therapy Medicinal Products in Europe and United States
Carolina Iglesias-Lopez et al.
FRONTIERS IN PHARMACOLOGY (2019)
In-vitro and in-vivo difference in gene delivery by lithocholic acid-polyethyleneimine conjugate
Jianping Wang et al.
BIOMATERIALS (2019)
Liposomal formulations of photosensitizers
Sanjana Ghosh et al.
BIOMATERIALS (2019)
Biodegradable polymers and constructs: A novel approach in drug delivery
Shiv Kumar Prajapati et al.
EUROPEAN POLYMER JOURNAL (2019)
Nanotheranostic Pluronic-Like Polymeric Micelles: Shedding Light into the Dark Shadows of Tumors
Catia Domingues et al.
MOLECULAR PHARMACEUTICS (2019)
Pediatric drug development in China: Reforms and challenges
Weijia Wu et al.
PHARMACOLOGICAL RESEARCH (2019)
Genetic engineering of hematopoiesis: current stage of clinical translation and future perspectives
Luigi Naldini
EMBO MOLECULAR MEDICINE (2019)
Intrabone hematopoietic stem cell gene therapy for adult and pediatric patients affected by transfusion-dependent β-thalassemia
Sarah Marktel et al.
NATURE MEDICINE (2019)
The journey to CAR T cell therapy: the pediatric and young adult experience with relapsed or refractory B-ALL
George Hucks et al.
BLOOD CANCER JOURNAL (2019)
The Meanings of Pediatric Drug Development
Klaus Rose et al.
THERAPEUTIC INNOVATION & REGULATORY SCIENCE (2019)
The age of paediatrics
Susan M. Sawyer et al.
LANCET CHILD & ADOLESCENT HEALTH (2019)
Pharmacology related to paediatric anaesthesia
Meghna Maheshwari et al.
INDIAN JOURNAL OF ANAESTHESIA (2019)
A Perspective on Microneedle-Based Drug Delivery and Diagnostics in Paediatrics
Liliana R. Pires et al.
JOURNAL OF PERSONALIZED MEDICINE (2019)
Accuracy of intravenous and enteral preparations involving small volumes for paediatric use: a review
L. P. Ainscough et al.
EUROPEAN JOURNAL OF HOSPITAL PHARMACY (2018)
Drug-gut microbiota interactions: implications for neuropharmacology
Jacinta Walsh et al.
BRITISH JOURNAL OF PHARMACOLOGY (2018)
CAR-T in the clinic: drive with care
Rafael J. Yanez-Munoz et al.
GENE THERAPY (2018)
Challenges for pulmonary delivery of high powder doses
Imco Sibum et al.
INTERNATIONAL JOURNAL OF PHARMACEUTICS (2018)
Novel adhesive hyaluronic acid based solid dosage form for pediatric application
Flavia Laffleur
JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY (2018)
Biodegradable dendrimers for drug delivery
Da Huang et al.
MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2018)
The uncertain fate of the National Institutes of Health (NIH) pediatric research portfolio
Daniel P. Gitterman et al.
PEDIATRIC RESEARCH (2018)
Useful pharmacodynamic endpoints in children: selection, measurement, and next steps
Lauren E. Kelly et al.
PEDIATRIC RESEARCH (2018)
Ultrasonic synthesis and characterization of poly(acrylamide)-co-poly (vinylimidazole)@MWCNTs composite for use as an electrochemical material
Won-Yong Jeon et al.
ULTRASONICS SONOCHEMISTRY (2018)
Nanomedicines for Pediatric Cancers
Carlos Rodriguez-Nogales et al.
ACS NANO (2018)
Epithelial-mesenchymal transition and microRNAs: Challenges and future perspectives in oral cancer
Catia Sofia da Costa Domingues et al.
HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK (2018)
Public health applications of CRISPR: How children's health can benefit
Vivian S. Vigliotti et al.
SEMINARS IN PERINATOLOGY (2018)
Buccal Dosage Forms: General Considerations for Pediatric Patients
Soledad Montero-Padilla et al.
AAPS PHARMSCITECH (2017)
Paclitaxel: What has been done and the challenges remain ahead
Ezequiel Bernabeu et al.
INTERNATIONAL JOURNAL OF PHARMACEUTICS (2017)
PEG-PCL-based nanomedicines: A biodegradable drug delivery system and its application
Philip Grossen et al.
JOURNAL OF CONTROLLED RELEASE (2017)
Hematopoietic Stem-Cell Gene Therapy for Cerebral Adrenoleukodystrophy
Florian Eichler et al.
NEW ENGLAND JOURNAL OF MEDICINE (2017)
Liposomal Formulations in Clinical Use: An Updated Review
Upendra Bulbake et al.
PHARMACEUTICS (2017)
Addressing the challenge of high-priced prescription drugs in the era of precision medicine: A systematic review of drug life cycles, therapeutic drug markets and regulatory frameworks
Toon van der Gronde et al.
PLOS ONE (2017)
Personalized Nanomedicine: A Revolution at the Nanoscale
Cristina Fornaguera et al.
JOURNAL OF PERSONALIZED MEDICINE (2017)
Enhancing the Pediatric Drug Development Framework to Deliver Better Pediatric Therapies Tomorrow
Christina Bucci-Rechtweg
CLINICAL THERAPEUTICS (2017)
Challenges Associated with Route of Administration in Neonatal Drug Delivery
Matthew W. Linakis et al.
CLINICAL PHARMACOKINETICS (2016)
Safe and effective pharmacotherapy in infants and preschool children: importance of formulation aspects
Diana A. van Riet-Nales et al.
ARCHIVES OF DISEASE IN CHILDHOOD (2016)
Oral drug dosage forms administered to hospitalized children: Analysis of 117,665 oral administrations in a French paediatric hospital over a 1-year period.
A. Lajoinie et al.
INTERNATIONAL JOURNAL OF PHARMACEUTICS (2016)
Development and in vivo evaluation of child-friendly lopinavir/ritonavir pediatric granules utilizing novel in situ self-assembly nanoparticles
Kevin Pham et al.
JOURNAL OF CONTROLLED RELEASE (2016)
Lentiviral haemopoietic stem-cell gene therapy in early-onset metachromatic leukodystrophy: an ad-hoc analysis of a non-randomised, open-label, phase 1/2 trial
Mario Sessa et al.
LANCET (2016)
Poly(amidoamine) (PAMAM): An emerging material for electrochemical bio(sensing) applications
Elif Burcu Bahadir et al.
TALANTA (2016)
CRISPR/Cas9-based genetic correction for recessive dystrophic epidermolysis bullosa
Beau R. Webber et al.
NPJ REGENERATIVE MEDICINE (2016)
How Does In Vivo Biliary Elimination of Drugs Change with Age? Evidence from In Vitro and Clinical Data Using a Systems Pharmacology Approach
Trevor N. Johnson et al.
DRUG METABOLISM AND DISPOSITION (2016)
Triazine-modified dendrimer for efficient TRAIL gene therapy in osteosarcoma
Yu Wang et al.
ACTA BIOMATERIALIA (2015)
Tumor microenvironment sensitive doxorubicin delivery and release to glioma using angiopep-2 decorated gold nanoparticles
Shaobo Ruan et al.
BIOMATERIALS (2015)
Formulations for children: problems and solutions
Hannah K. Batchelor et al.
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY (2015)
Challenges in CRISPR/CAS9 Delivery: Potential Roles of Nonviral Vectors
Ling Li et al.
HUMAN GENE THERAPY (2015)
The STEP database through the end-users eyes-USABILITY STUDY
Smita Salunke et al.
INTERNATIONAL JOURNAL OF PHARMACEUTICS (2015)
Outcomes Following Gene Therapy in Patients With Severe Wiskott-Aldrich Syndrome
Salima Hacein-Bey Abina et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2015)
Hyaluronic acid targeting of CD44 for cancer therapy: from receptor biology to nanomedicine
George Mattheolabakis et al.
JOURNAL OF DRUG TARGETING (2015)
Definition of a Pediatrician
Mary Ellen Rimsza et al.
PEDIATRICS (2015)
Safety of Excipients in Pediatric Formulations-A Call for Toxicity Studies in Juvenile Animals?
Georg Schmitt
CHILDREN-BASEL (2015)
Nanoemulsions in Translational Research-Opportunities and Challenges in Targeted Cancer Therapy
Srinivas Ganta et al.
AAPS PHARMSCITECH (2014)
Playing hide and seek with poorly tasting paediatric medicines: Do not forget the excipients
Jennifer Walsh et al.
ADVANCED DRUG DELIVERY REVIEWS (2014)
Effective use of transdermal drug delivery in children
M. Begona Delgado-Charro et al.
ADVANCED DRUG DELIVERY REVIEWS (2014)
Oral transmucosal drug delivery for pediatric use
Jenny K. W. Lam et al.
ADVANCED DRUG DELIVERY REVIEWS (2014)
Paediatric drug development: The impact of evolving regulations
M. A. Turner et al.
ADVANCED DRUG DELIVERY REVIEWS (2014)
Gene and cell therapy for children - New medicines, new challenges?
Karen F. Buckland et al.
ADVANCED DRUG DELIVERY REVIEWS (2014)
Nanomedicines in the future of pediatric therapy
Alejandro Sosnik et al.
ADVANCED DRUG DELIVERY REVIEWS (2014)
Pharmacokinetic/pharmacodynamic modelling approaches in paediatric infectious diseases and immunology
Charlotte I. S. Barker et al.
ADVANCED DRUG DELIVERY REVIEWS (2014)
Patient-Centred Pharmaceutical Design to Improve Acceptability of Medicines: Similarities and Differences in Paediatric and Geriatric Populations
Fang Liu et al.
DRUGS (2014)
Carboplatin loaded protein nanoparticles exhibit improve anti-proliferative activity in retinoblastoma cells
Farhan Ahmed et al.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2014)
Clinical and economic implications of the use of nanoparticle paclitaxel (Nanoxel) in India
A. A. Ranade et al.
ANNALS OF ONCOLOGY (2013)
The STEP (Safety and Toxicity of Excipients for Paediatrics) database: Part 2-The pilot version
Smita Salunke et al.
INTERNATIONAL JOURNAL OF PHARMACEUTICS (2013)
Preclinical Evaluation of Genexol-PM, a Nanoparticle Formulation of Paclitaxel, as a Novel Radiosensitizer for the Treatment of Non-Small Cell Lung Cancer
Michael E. Werner et al.
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2013)
Dexamethasone-Loaded Block Copolymer Nanoparticles Induce Leukemia Cell Death and Enhance Therapeutic Efficacy: A Novel Application in Pediatric Nanomedicine
Vinu Krishnan et al.
MOLECULAR PHARMACEUTICS (2013)
Next-generation nanomedicines and nanosimilars: EU regulators' initiatives relating to the development and evaluation of nanomedicines
Falk Ehmann et al.
NANOMEDICINE (2013)
Lentiviral Hematopoietic Stem Cell Gene Therapy in Patients with Wiskott-Aldrich Syndrome
Alessandro Aiuti et al.
SCIENCE (2013)
Lentiviral Hematopoietic Stem Cell Gene Therapy Benefits Metachromatic Leukodystrophy
Alessandra Biffi et al.
SCIENCE (2013)
Whither Advanced Therapy Medicinal Products?
Mark D. Smith et al.
TRANSFUSION MEDICINE AND HEMOTHERAPY (2013)
Off-Label Drug Use in Pediatric Patients
E. Kimland et al.
CLINICAL PHARMACOLOGY & THERAPEUTICS (2012)
The STEP (Safety and Toxicity of Excipients for Paediatrics) database. Part 1-A need assessment study
Smita Salunke et al.
INTERNATIONAL JOURNAL OF PHARMACEUTICS (2012)
Doxil® - The first FDA-approved nano-drug: Lessons learned
Yechezkel (Chezy) Barenholz
JOURNAL OF CONTROLLED RELEASE (2012)
Applications of Nanotechnology in Dermatology
Lisa A. DeLouise
JOURNAL OF INVESTIGATIVE DERMATOLOGY (2012)
HISTORY OF MEDICINE Reform, Regulation, and Pharmaceuticals - The Kefauver-Harris Amendments at 50
Jeremy A. Greene et al.
NEW ENGLAND JOURNAL OF MEDICINE (2012)
Poly Lactic-co-Glycolic Acid (PLGA) as Biodegradable Controlled Drug Delivery Carrier
Hirenkumar K. Makadia et al.
POLYMERS (2011)
Factors and Mechanisms for Pharmacokinetic Differences between Pediatric Population and Adults
Eva Fernandez et al.
Pharmaceutics (2011)
A chitosan hydrogel delivery system for osteosarcoma gene therapy with pigment epithelium-derived factor combined with chemotherapy
Hang T. Ta et al.
BIOMATERIALS (2009)
Hematopoietic Stem Cell Gene Therapy with a Lentiviral Vector in X-Linked Adrenoleukodystrophy
Nathalie Cartier et al.
SCIENCE (2009)
Using ontogeny information to build predictive models for drug elimination
Jane Alcorn et al.
DRUG DISCOVERY TODAY (2008)
Developing paediatric medicines: identifying the needs and recognizing the challenges
Terry B. Ernest et al.
JOURNAL OF PHARMACY AND PHARMACOLOGY (2007)
Translating pharmacogenetics and pharmacogenomics into drug development for clinical pediatrics and beyond
JS Leeder
DRUG DISCOVERY TODAY (2004)
Children versus adults: Pharmacokinetic and adverse-effect differences
GD Anderson
EPILEPSIA (2002)