4.6 Article

Radiation doses to mediastinal organs at risk in early-stage unfavorable Hodgkin lymphoma- a risk stratified analysis of the GHSG HD17 trial

Related references

Note: Only part of the references are listed.
Article Oncology

Nivolumab and Doxorubicin, Vinblastine, and Dacarbazine in Early-Stage Unfavorable Hodgkin Lymphoma: Final Analysis of the Randomized German Hodgkin Study Group Phase II NIVAHL Trial

Paul J. Broeckelmann et al.

Summary: This study reports the final analysis of the NIVAHL trial, which evaluated the efficacy and safety of a combined treatment approach for early-stage unfavorable classical Hodgkin lymphoma. The results showed high complete remission rates, 1-year progression-free survival, and overall survival in the patient population. Long-term safety data also demonstrated the relatively favorable profile of this therapeutic approach.

JOURNAL OF CLINICAL ONCOLOGY (2023)

Article Oncology

Radiation Therapy in the German Hodgkin Study Group HD 16 and HD 17 Trials: Quality Assurance and Dosimetric Analysis for Hodgkin Lymphoma in the Modern Era

Michael Oertel et al.

Summary: The latest studies from the German Hodgkin Study Group (GHSG) show improved quality in radiation therapy (RT) for early-stage Hodgkin lymphoma. The use of involved-node radiation therapy (INRT) has resulted in better outcomes compared to previous studies. The choice of RT technique and design plays a crucial role in treatment efficacy.

ADVANCES IN RADIATION ONCOLOGY (2023)

Editorial Material Oncology

Treatment algorithm for patients with Hodgkin's lymphoma

Andreas Engert

ONKOLOGIE (2022)

Article Oncology

Predictive value of baseline metabolic tumor volume in early-stage favorable Hodgkin Lymphoma - Data from the prospective, multicenter phase III HD16 trial

Lutz van Heek et al.

Summary: This study aimed to explore the predictive relevance of metabolic tumor volume (MTV) and total lesion glycolysis (TLG) in early stage Hodgkin lymphoma patients. The results showed that using a fixed threshold of SUV4.0 for calculating MTV and TLG provided the highest predictive performance.

BMC CANCER (2022)

Article Oncology

Impact of radiation techniques on lung toxicity in patients with mediastinal Hodgkin's lymphoma

Niklas Benedikt Pepper et al.

Summary: Mediastinal radiotherapy for Hodgkin's lymphoma, especially when combined with bleomycin, may lead to significant pulmonary morbidity and mortality. The use of modern techniques like intensity-modulated radiotherapy (IMRT) is becoming more popular for sparing organs at risk. Analysis of different radiation techniques showed a significant decrease in lung toxicity risk with standard APPA plans compared to IMRT plans, with 7-field IMRT posing a higher risk than 5-field IMRT.

STRAHLENTHERAPIE UND ONKOLOGIE (2021)

Article Oncology

Long-Term Cause-Specific Mortality in Hodgkin Lymphoma Patients

Simone de Vries et al.

Summary: Compared with the general population, Hodgkin lymphoma survivors have a substantially reduced life expectancy. Therefore, optimal selection of patients for primary CT is crucial, weighing risks of HL relapse and long-term toxicity.

JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2021)

Review Medicine, General & Internal

Late Sequelae of Radiotherapy

Ulrike Hoeller et al.

Summary: The article reviews the research on late sequelae of radiotherapy for tumors, discussing late sequelae affecting different parts of the body and radiobiological mechanisms and treatment methods. Ongoing improvements in various technologies have reduced the side effects of radiotherapy, but further large-scale studies are needed to address related issues.

DEUTSCHES ARZTEBLATT INTERNATIONAL (2021)

Article Oncology

Predicted Risks of Cardiovascular Disease Following Chemotherapy and Radiotherapy in the UK NCRI RAPID Trial of Positron Emission Tomography-Directed Therapy for Early-Stage Hodgkin Lymphoma

David J. Cutter et al.

Summary: This study aims to provide information on the risk of radiation-related cardiovascular disease in early-stage Hodgkin lymphoma patients to help personalize radiotherapy delivery. The predicted excess cardiovascular risk is small for most patients, suggesting that radiotherapy may provide a net benefit.

JOURNAL OF CLINICAL ONCOLOGY (2021)

Article Oncology

Quality control of involved field radiotherapy in the HD 13 and HD 14 trials

J. Kriz et al.

STRAHLENTHERAPIE UND ONKOLOGIE (2017)

Article Oncology

Relapse Analysis of Irradiated Patients Within the HD15 Trial of the German Hodgkin Study Group

Jan Kriz et al.

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2015)

Article Oncology

Risk for Valvular Heart Disease After Treatment for Hodgkin Lymphoma

David J. Cutter et al.

JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2015)

Article Medicine, General & Internal

Results of a Trial of PET-Directed Therapy for Early-Stage Hodgkin's Lymphoma

John Radford et al.

NEW ENGLAND JOURNAL OF MEDICINE (2015)

Article Medicine, General & Internal

Second Cancer Risk Up to 40 Years after Treatment for Hodgkin's Lymphoma

Michael Schaapveld et al.

NEW ENGLAND JOURNAL OF MEDICINE (2015)

Article Oncology

Risk for Valvular Heart Disease After Treatment for Hodgkin Lymphoma

David J. Cutter et al.

JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2015)

Article Oncology

Modern Radiation Therapy for Hodgkin Lymphoma: Field and Dose Guidelines From the International Lymphoma Radiation Oncology Group (ILROG)

Lena Specht et al.

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2014)

Article Medicine, General & Internal

Risk of Ischemic Heart Disease in Women after Radiotherapy for Breast Cancer

Sarah C. Darby et al.

NEW ENGLAND JOURNAL OF MEDICINE (2013)

Article Oncology

Involved-node radiotherapy in early-stage Hodgkin's lymphoma

Hans Theodor Eich et al.

STRAHLENTHERAPIE UND ONKOLOGIE (2008)

Article Hematology

Late cardiotoxicity after treatment for Hodgkin lymphoma

Berthe M. P. Aleman et al.

BLOOD (2007)

Article Oncology

Initiation of a teleradiotherapeutic network for patients in German lymphoma studies

HT Eich et al.

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2004)

Article Oncology

Long-term cause-specific mortality of patients treated for Hodgkin's disease

BMP Aleman et al.

JOURNAL OF CLINICAL ONCOLOGY (2003)