Related references
Note: Only part of the references are listed.Neoadjuvant Pembrolizumab in Localized Microsatellite Instability High/Deficient Mismatch Repair Solid Tumors
Kaysia Ludford et al.
JOURNAL OF CLINICAL ONCOLOGY (2023)
Neoadjuvant Immunotherapy Leads to Major Response and Low Recurrence in Localized Mismatch Repair–Deficient Colorectal Cancer
Bin-Yi Xiao et al.
Journal of the National Comprehensive Cancer Network (2023)
γδ T cells are effectors of immunotherapy in cancers with HLA class I defects
Natasja L. de Vries et al.
NATURE (2023)
Meta-analysis of neoadjuvant immunotherapy for non-metastatic colorectal cancer
Long Zhou et al.
FRONTIERS IN IMMUNOLOGY (2023)
Advances in immune checkpoint inhibitor combination strategies for microsatellite stable colorectal cancer
Javier Ros et al.
FRONTIERS IN ONCOLOGY (2023)
Plasmatic BRAF-V600E allele fraction as a prognostic factor in metastatic colorectal cancer treated with BRAF combinatorial treatments
J. Ros et al.
ANNALS OF ONCOLOGY (2023)
Metastatic colorectal cancer: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up
A. Cervantes et al.
ANNALS OF ONCOLOGY (2023)
Pembrolizumab for previously treated, microsatellite instability-high/mismatch repair-deficient advanced colorectal cancer: final analysis of KEYNOTE-164
Dung T. Le et al.
EUROPEAN JOURNAL OF CANCER (2023)
Codon-specific KRAS mutations predict survival benefit of trifluridine/tipiracil in metastatic colorectal cancer
Joris van de Haar et al.
NATURE MEDICINE (2023)
Neoadjuvant immunotherapy for melanoma is now ready for clinical practice
Claus Garbe et al.
NATURE MEDICINE (2023)
BRAF V600E/RAS Mutations and Lynch Syndrome in Patients With MSI-H/dMMR Metastatic Colorectal Cancer Treated With Immune Checkpoint Inhibitors
Raphael Colle et al.
ONCOLOGIST (2023)
Association Between Survival and Metastatic Site in Mismatch Repair-Deficient Metastatic Colorectal Cancer Treated With First-line Pembrolizumab
Bahar Saberzadeh-Ardestani et al.
JAMA NETWORK OPEN (2023)
Tumour mutational burden as a biomarker in patients with mismatch repair deficient/microsatellite instability- high metastatic colorectal cancer treated with immune checkpoint inhibitors
Paolo Manca et al.
EUROPEAN JOURNAL OF CANCER (2023)
Treatment of BRAF-V600E mutant metastatic colorectal cancer: new insights and biomarkers
Javier Ros et al.
EXPERT REVIEW OF ANTICANCER THERAPY (2023)
First-Line Nivolumab Plus Low-Dose Ipilimumab for Microsatellite Instability-High/Mismatch Repair-Deficient Metastatic Colorectal Cancer: The Phase II CheckMate 142 Study
Heinz-Josef Lenz et al.
JOURNAL OF CLINICAL ONCOLOGY (2022)
Neoadjuvant PD-1 blockade with toripalimab, with or without celecoxib, in mismatch repair-deficient or microsatellite instability-high, locally advanced, colorectal cancer (P1CC): a single-centre, parallel-group, noncomparative, randomised, phase 2 trial
Huabin Hu et al.
LANCET GASTROENTEROLOGY & HEPATOLOGY (2022)
Landscape of Immunotherapy Options for Colorectal Cancer: Current Knowledge and Future Perspectives beyond Immune Checkpoint Blockade
Alecsandra Gorzo et al.
LIFE-BASEL (2022)
Organ Preservation in Patients With Rectal Adenocarcinoma Treated With Total Neoadjuvant Therapy
Julio Garcia-Aguilar et al.
JOURNAL OF CLINICAL ONCOLOGY (2022)
B2M and JAK1/2-mutated MSI-H Colorectal Carcinomas Can Benefit From Anti-PD-1 Therapy
Chenzhi Zhang et al.
JOURNAL OF IMMUNOTHERAPY (2022)
Pembrolizumab versus chemotherapy for microsatellite instability-high or mismatch repair-deficient metastatic colorectal cancer (KEYNOTE-177): final analysis of a randomised, open-label, phase 3 study
Luis A. Diaz et al.
LANCET ONCOLOGY (2022)
Botensilimab, a novel innate/adaptive immune activator, plus balstilimab (anti-PD-1) for metastatic heavily pretreated microsatellite stable colorectal cancer
A. Bullock et al.
ANNALS OF ONCOLOGY (2022)
Nivolumab plus low-dose ipilimumab in previously treated patients with microsatellite instability-high/mismatch repair-deficient metastatic colorectal cancer: 4-year follow-up from CheckMate 142
T. Andre et al.
ANNALS OF ONCOLOGY (2022)
PD-1 Blockade in Mismatch Repair-Deficient, Locally Advanced Rectal Cancer
Andrea Cercek et al.
NEW ENGLAND JOURNAL OF MEDICINE (2022)
Immunotherapy for Microsatellite Stable Colorectal Cancers: Challenges and Novel Therapeutic Avenues
Ibrahim Halil Sahin et al.
American Society of Clinical Oncology educational book / ASCO. American Society of Clinical Oncology. Meeting (2022)
A phase I clinical trial of regorafenib, ipilimumab, and nivolumab (RIN) in chemotherapy resistant MSS metastatic colorectal cancer (mCRC)
M. G. Fakih et al.
ANNALS OF ONCOLOGY (2022)
Neoadjuvant immune checkpoint inhibition in locally advanced MMR-deficient colon cancer: The NICHE-2 study
M. Chalabi et al.
ANNALS OF ONCOLOGY (2022)
Efficacy and safety of anti-PD-1/PD-L1 therapy in the treatment of advanced colorectal cancer: a meta-analysis
Yuegang Li et al.
BMC GASTROENTEROLOGY (2022)
Avelumab versus standard second line treatment chemotherapy in metastatic colorectal cancer patients with microsatellite instability: The SAMCO-PRODIGE 54 randomised phase II trial
Julien Taieb et al.
DIGESTIVE AND LIVER DISEASE (2021)
Safety and efficacy of anti-PD-1 antibody dostarlimab in patients (pts) with mismatch repair-deficient (dMMR) solid cancers: Results from GARNET study.
Thierry Andre et al.
JOURNAL OF CLINICAL ONCOLOGY (2021)
Short-course radiotherapy followed by chemotherapy before total mesorectal excision (TME) versus preoperative chemoradiotherapy, TME, and optional adjuvant chemotherapy in locally advanced rectal cancer (RAPIDO): a randomised, open-label, phase 3 trial
Renu R. Bahadoer et al.
LANCET ONCOLOGY (2021)
Liver metastasis restrains immunotherapy efficacy via macrophage-mediated T cell elimination
Jiali Yu et al.
NATURE MEDICINE (2021)
Immunogenomics of Colorectal Cancer Response to Checkpoint Blockade: Analysis of the KEYNOTE 177 Trial and Validation Cohorts
Michele Bortolomeazzi et al.
GASTROENTEROLOGY (2021)
Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries
Hyuna Sung et al.
CA-A CANCER JOURNAL FOR CLINICIANS (2021)
Pseudoprogression in patients treated with immune checkpoint inhibitors for microsatellite instability-high/mismatch repair-deficient metastatic colorectal cancer
Raphael Colle et al.
EUROPEAN JOURNAL OF CANCER (2021)
Pathological response and survival with neoadjuvant therapy in melanoma: a pooled analysis from the International Neoadjuvant Melanoma Consortium (INMC)
Alexander M. Menzies et al.
NATURE MEDICINE (2021)
Adrenal gland as a sanctuary site for immunotherapy in patients with microsatellite instability-high metastatic colorectal cancer
Romain Cohen et al.
JOURNAL FOR IMMUNOTHERAPY OF CANCER (2021)
The Spectrum of Benefit from Checkpoint Blockade in Hypermutated Tumors
Benoit Rousseau et al.
NEW ENGLAND JOURNAL OF MEDICINE (2021)
Discordance between immunochemistry of mismatch repair proteins and molecular testing of microsatellite instability in colorectal cancer
A. Guyot D'Asnieres De Salins et al.
ESMO OPEN (2021)
Phase II Open-Label Study of Pembrolizumab in Treatment-Refractory, Microsatellite Instability-High/Mismatch Repair-Deficient Metastatic Colorectal Cancer: KEYNOTE-164
Dung T. Le et al.
JOURNAL OF CLINICAL ONCOLOGY (2020)
Genetic and epigenetic analysis of the beta-2-microglobulin gene in microsatellite instable colorectal cancer
Zuzana Snahnicanova et al.
CLINICAL AND EXPERIMENTAL MEDICINE (2020)
Distinct Immunological Landscapes Characterize Inherited and Sporadic Mismatch Repair Deficient Endometrial Cancer
Neal C. Fiamchander et al.
FRONTIERS IN IMMUNOLOGY (2020)
Effect of Combined Immune Checkpoint Inhibition vs Best Supportive Care Alone in Patients With Advanced Colorectal Cancer The Canadian Cancer Trials Group CO.26 Study
Eric X. Chen et al.
JAMA ONCOLOGY (2020)
Neoadjuvant immunotherapy leads to pathological responses in MMR-proficient and MMR-deficient early-stage colon cancers
Myriam Chalabi et al.
NATURE MEDICINE (2020)
Localised colon cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up
G. Argiles et al.
ANNALS OF ONCOLOGY (2020)
Autoimmune diseases and immune-checkpoint inhibitors for cancer therapy: review of the literature and personalized risk-based prevention strategy
J. Haanen et al.
ANNALS OF ONCOLOGY (2020)
Association of tumour mutational burden with outcomes in patients with advanced solid tumours treated with pembrolizumab: prospective biomarker analysis of the multicohort, open-label, phase 2 KEYNOTE-158 study
Aurelien Marabelle et al.
LANCET ONCOLOGY (2020)
Pembrolizumab in Microsatellite-Instability-High Advanced Colorectal Cancer
T. Andre et al.
NEW ENGLAND JOURNAL OF MEDICINE (2020)
RECIST and iRECIST criteria for the evaluation of nivolumab plus ipilimumab in patients with microsatellite instability-high/mismatch repair-deficient metastatic colorectal cancer: the GERCOR NIPICOL phase II study
Romain Cohen et al.
JOURNAL FOR IMMUNOTHERAPY OF CANCER (2020)
MSI/MMR-deficient tumor diagnosis: Which standard for screening and for diagnosis? Diagnostic modalities for the colon and other sites: Differences between tumors
Magali Svrcek et al.
BULLETIN DU CANCER (2019)
Safety and clinical activity of durvalumab monotherapy in patients with microsatellite instability high (MSI-H) tumors.
Neil Howard Segal et al.
JOURNAL OF CLINICAL ONCOLOGY (2019)
Mutational Analysis of Patients With Colorectal Cancer in CALGB/SWOG 80405 Identifies New Roles of Microsatellite Instability and Tumor Mutational Burden for Patient Outcome
Federico Innocenti et al.
JOURNAL OF CLINICAL ONCOLOGY (2019)
Tumor mutational burden is predictive of response to immune checkpoint inhibitors in MSI-high metastatic colorectal cancer
A. B. Schrock et al.
ANNALS OF ONCOLOGY (2019)
Immunotherapy in organ-transplanted cancer patients: efficacy and risk of organ rejection
J. Ros et al.
ANNALS OF ONCOLOGY (2019)
CANCER Genetic diversity of tumors with mismatch repair deficiency influences anti-PD-1 immunotherapy response
Rajarsi Mandal et al.
SCIENCE (2019)
Analysis of Plasma Cell-Free DNA by Ultradeep Sequencing in Patients With Stages I to III Colorectal Cancer
Thomas Reinert et al.
JAMA ONCOLOGY (2019)
Best practices for bioinformatic characterization of neoantigens for clinical utility
Megan M. Richters et al.
GENOME MEDICINE (2019)
Mutation Burden and I Index for Detection of Microsatellite Instability in Colorectal Cancer by Targeted Next-Generation Sequencing
Jeong E. Kim et al.
JOURNAL OF MOLECULAR DIAGNOSTICS (2019)
Alternative tumour-specific antigens
Christof C. Smith et al.
NATURE REVIEWS CANCER (2019)
High numbers of PDCD1 (PD-1)-positive T cells and B2M mutations in microsatellite-unstable colorectal cancer
Jonas Janikovits et al.
ONCOIMMUNOLOGY (2018)
Durable Clinical Benefit With Nivolumab Plus Ipilimumab in DNA Mismatch Repair-Deficient/Microsatellite Instability-High Metastatic Colorectal Cancer
Michael J. Overman et al.
JOURNAL OF CLINICAL ONCOLOGY (2018)
The Heterogeneity Between Lynch-Associated and Sporadic MMR Deficiency in Colorectal Cancers
Guo-Chen Liu et al.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2018)
Immune recognition of somatic mutations leading to complete durable regression in metastatic breast cancer
Nikolaos Zacharakis et al.
NATURE MEDICINE (2018)
Genetic Mechanisms of Immune Evasion in Colorectal Cancer
Catherine S. Grasso et al.
CANCER DISCOVERY (2018)
STK11/LKB1 Mutations and PD-1 Inhibitor Resistance in KRAS-Mutant Lung Adenocarcinoma
Ferdinandos Skoulidis et al.
CANCER DISCOVERY (2018)
The Heterogeneity Between Lynch-Associated and Sporadic MMR Deficiency in Colorectal Cancers
Guo-Chen Liu et al.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2018)
Nivolumab in patients with DNA mismatch repairdeficient/microsatellite instability-high (dMMR/MSI-H) metastatic colorectal cancer (mCRC): Long-term survival according to prior line of treatment from CheckMate-142.
Michael J. Overman et al.
JOURNAL OF CLINICAL ONCOLOGY (2018)
Immune targets and neoantigens for cancer immunotherapy and precision medicine
Rong-Fu Wang et al.
CELL RESEARCH (2017)
Clinical and molecular characterisation of hereditary and sporadic metastatic colorectal cancers harbouring microsatellite instability/DNA mismatch repair deficiency
R. Cohen et al.
EUROPEAN JOURNAL OF CANCER (2017)
Response to PD-1 Blockade in Microsatellite Stable Metastatic Colorectal Cancer Harboring a POLE. Mutation
Jun Gong et al.
JOURNAL OF THE NATIONAL COMPREHENSIVE CANCER NETWORK (2017)
Nivolumab in patients with metastatic DNA mismatch repair-deficient or microsatellite instability-high colorectal cancer (CheckMate 142): an open-label, multicentre, phase 2 study
Michael J. Overman et al.
LANCET ONCOLOGY (2017)
Phase I Escalating-Dose Trial of CAR-T Therapy Targeting CEA+ Metastatic Colorectal Cancers
Chengcheng Zhang et al.
MOLECULAR THERAPY (2017)
A molecular portrait of microsatellite instability across multiple cancers
Isidro Cortes-Ciriano et al.
NATURE COMMUNICATIONS (2017)
Multilevel genomics of colorectal cancers with microsatellite instability-clinical impact of JAK1 mutations and consensus molecular subtype 1
Anita Sveen et al.
GENOME MEDICINE (2017)
Liver Metastasis and Treatment Outcome with Anti-PD-1 Monoclonal Antibody in Patients with Melanoma and NSCLC
Paul C. Tumeh et al.
CANCER IMMUNOLOGY RESEARCH (2017)
Loss of function JAK1 mutations occur at high frequency in cancers with microsatellite instability and are suggestive of immune evasion
Lee A. Albacker et al.
PLOS ONE (2017)
T-Cell Transfer Therapy Targeting Mutant KRAS in Cancer
Eric Tran et al.
NEW ENGLAND JOURNAL OF MEDICINE (2016)
Circulating tumor DNA analysis detects minimal residual disease and predicts recurrence in patients with stage II colon cancer
Jeanne Tie et al.
SCIENCE TRANSLATIONAL MEDICINE (2016)
Cyclooxygenase-Dependent Tumor Growth through Evasion of Immunity
Santiago Zelenay et al.
CELL (2015)
Phase I Hepatic Immunotherapy for Metastases Study of Intra-Arterial Chimeric Antigen Receptor-Modified T-cell Therapy for CEA+ Liver Metastases
Steven C. Katz et al.
CLINICAL CANCER RESEARCH (2015)
PD-1 Blockade in Tumors with Mismatch-Repair Deficiency
D. T. Le et al.
NEW ENGLAND JOURNAL OF MEDICINE (2015)
Characterization of the immunophenotypes and antigenomes of colorectal cancers reveals distinct tumor escape mechanisms and novel targets for immunotherapy
Mihaela Angelova et al.
GENOME BIOLOGY (2015)
The Vigorous Immune Microenvironment of Microsatellite Instable Colon Cancer Is Balanced by Multiple Counter-Inhibitory Checkpoints
Nicolas J. Llosa et al.
CANCER DISCOVERY (2015)
Colorectal cancer statistics, 2014
Rebecca Siegel et al.
CA-A CANCER JOURNAL FOR CLINICIANS (2014)
Cancer Immunotherapy Based on Mutation-Specific CD4+T Cells in a Patient with Epithelial Cancer
Eric Tran et al.
SCIENCE (2014)
A Randomized Phase II Study of Immunization With Dendritic Cells Modified With Poxvectors Encoding CEA and MUC1 Compared With the Same Poxvectors Plus GM-CSF for Resected Metastatic Colorectal Cancer
Michael A. Morse et al.
ANNALS OF SURGERY (2013)
Prognostic Impact of Deficient DNA Mismatch Repair in Patients With Stage III Colon Cancer From a Randomized Trial of FOLFOX-Based Adjuvant Chemotherapy
Frank A. Sinicrope et al.
JOURNAL OF CLINICAL ONCOLOGY (2013)
Microsatellite Instability and BRAF Mutation Testing in Colorectal Cancer Prognostication
Paul Lochhead et al.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2013)
Development and Independent Validation of a Prognostic Assay for Stage II Colon Cancer Using Formalin-Fixed Paraffin-Embedded Tissue
Richard D. Kennedy et al.
JOURNAL OF CLINICAL ONCOLOGY (2011)
Phase I/II Study of Oncolytic Herpes Simplex Virus NV1020 in Patients with Extensively Pretreated Refractory Colorectal Cancer Metastatic to the Liver
Sunil K. Geevarghese et al.
HUMAN GENE THERAPY (2010)
Effects of KRAS, BRAF, NRAS, and PIK3CA mutations on the efficacy of cetuximab plus chemotherapy in chemotherapy-refractory metastatic colorectal cancer: a retrospective consortium analysis
Wendy De Roock et al.
LANCET ONCOLOGY (2010)
Adoptive Cell Therapy for Patients With Metastatic Melanoma: Evaluation of Intensive Myeloablative Chemoradiation Preparative Regimens
Mark E. Dudley et al.
JOURNAL OF CLINICAL ONCOLOGY (2008)
Systematic review of microsatellite instability and colorectal cancer prognosis
S Popat et al.
JOURNAL OF CLINICAL ONCOLOGY (2005)
Mutations of the BRAF gene in human cancer
H Davies et al.
NATURE (2002)
Distinction between familial and sporadic forms of colorectal cancer showing DNA microsatellite instability
JR Jass et al.
EUROPEAN JOURNAL OF CANCER (2002)
Features of colorectal cancers with high-level microsatellite instability occurring in familial and sporadic settings - Parallel pathways of tumorigenesis
J Young et al.
AMERICAN JOURNAL OF PATHOLOGY (2001)