Journal
JOURNAL OF CLINICAL MEDICINE
Volume 12, Issue 21, Pages -Publisher
MDPI
DOI: 10.3390/jcm12216771
Keywords
pain pathways; colorectal surgery; multimodal analgesia
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Pain after surgery has negative effects on patient outcome. With the increase in less invasive surgical procedures and rapid discharge, it is important to re-evaluate analgesic strategies. This review highlights the complexity of surgical pain management and emphasizes the importance of a multimodal approach.
Pain is a complex entity with deleterious effects on the entire organism. Poorly controlled postoperative pain impacts the patient outcome, being associated with increased morbidity, inadequate quality of life and functional recovery. In the current surgical environment with less invasive surgical procedures increasingly being used and a trend towards rapid discharge home after surgery, we need to continuously re-evaluate analgesic strategies. We have performed a narrative review consisting of a description of the acute surgical pain anatomic pathways and the connection between pain and the surgical stress response followed by reviewing methods of multimodal analgesia in colorectal surgery found in recent literature data. We have described various regional analgesia techniques and drugs effective in pain treatment, emphasizing their advantages and concerns. We have also tried to identify present knowledge gaps requiring future research. Our review concludes that surgical pain has peculiarities that make its management complex, implying a consistent, multimodal approach aiming to block both peripheral and central pain pathways.
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