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The Effect of Transcranial Direct Current Stimulation (tDCS) on Cocaine Addiction: A Narrative Review

Journal

JOURNAL OF CLINICAL MEDICINE
Volume 12, Issue 20, Pages -

Publisher

MDPI
DOI: 10.3390/jcm12206511

Keywords

cocaine; crack; addiction; transcranial direct current stimulation; dorsolateral prefrontal cortex; tDCS; neuromodulation; cocaine use disorder

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This review discusses the application of transcranial direct current stimulation (tDCS) in treating cocaine addiction. The results indicate that applying tDCS to the right dorsolateral prefrontal cortex (DLPFC) holds promise for reducing drug cravings in individuals with cocaine addiction.
Cocaine addiction is a significant problem worldwide. The development of addiction involves a reward system, which consists of certain brain regions like the ventral tegmental area, nucleus accumbens, and prefrontal cortex. Currently, there are no approved medications for treating cocaine dependence, so researchers are actively searching for effective treatments that can impact the brain. One potential treatment under investigation is transcranial direct current stimulation (tDCS), a non-invasive method of stimulating the brain to modulate its activity. In this review, we explore the use of tDCS in treating cocaine addiction. We found nine relevant articles via a literature search, and the results indicate that applying tDCS to the right dorsolateral prefrontal cortex (DLPFC) holds promise for reducing drug cravings in individuals with cocaine addiction. The review also discusses the possible mechanisms by which tDCS works and provides recommendations for future research in this field.

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