4.6 Article

Simultaneous Presentation of Dexamethasone and Nerve Growth Factor via Layered Carbon Nanotubes and Polypyrrole to Interface Neural Cells

Related references

Note: Only part of the references are listed.
Article Nutrition & Dietetics

The different trends in the burden of neurological and mental disorders following dietary transition in China, the USA, and the world: An extension analysis for the Global Burden of Disease Study 2019

Shan Liang et al.

Summary: Research has found that the highly processed western diet is replacing traditional diets globally, leading to disruptions in gut microbiota and increased susceptibility to neurological and mental disorders. In contrast, a balanced diet can regulate gut microbiota and prevent these disorders. However, there is limited research on the association between the expanding burden of neurological and mental disorders and dietary transitions.

FRONTIERS IN NUTRITION (2023)

Review Engineering, Biomedical

Chemically revised conducting polymers with inflammation resistance for intimate bioelectronic electrocoupling

Sihao Qian et al.

Summary: Conducting polymers with mixed ionic-electronic conductivity, tunable interfacial barrier, tissue matchable softness, and versatile chemical functionalization are used to bridge the gap between brain tissue and electronic circuits. This review focuses on chemically revised conducting polymers, their superior electrochemical performance, and their applications in fabricating long-term bioelectronic implants. The challenges of chronic immune responses, weak neuron attraction, and long-term electrocommunication instability are addressed, and the promising progress of zwitterionic conducting polymers is highlighted.

BIOACTIVE MATERIALS (2023)

Article Electrochemistry

Fabrication of vertically aligned PEDOT nanotube arrays on microelectrodes to interface neurons

Hai-lan Chen et al.

Summary: By fabricating PEDOT nanotube array modified microelectrodes, this study successfully improved the electrical properties of neural electrodes, promoted cell adhesion and growth, and increased neurite extension and branching. In vitro experiments demonstrated that the PEDOT nanotube arrays provided good support for cells, even without the presence of other cell adhesion-promoting molecules.

ELECTROCHIMICA ACTA (2022)

Review Nanoscience & Nanotechnology

Where do we stand now regarding treatment of psychiatric and neurodegenerative disorders? Considerations in using magnetoelectric nanoparticles as an innovative approach

Marta Pardo et al.

Summary: Almost 1 billion people worldwide have been diagnosed with mental health or substance disorders, causing a significant burden to society and resulting in around 8 million deaths annually. Despite daily advancements in methods to treat patients, the brain remains the most unknown and complex organ of the body. The recent introduction of magnetoelectric nanoparticles (MENPs) shows potential to revolutionize the treatment of brain alterations, offering wirelessly controlled stimulation at a single-neuron level without genetic modification or reported toxicity.

WILEY INTERDISCIPLINARY REVIEWS-NANOMEDICINE AND NANOBIOTECHNOLOGY (2022)

Article Engineering, Biomedical

Polydopamine-coated polycaprolactone/carbon nanotube fibrous scaffolds loaded with brain-derived neurotrophic factor for peripheral nerve regeneration

Wei Pi et al.

Summary: This study fabricated aligned conductive scaffolds composed of carbon nanotubes (CNTs) via electrospinning and loaded brain-derived neurotrophic factor (BDNF) onto the scaffolds. The results showed that the scaffolds effectively promoted peripheral nerve regeneration both in vitro and in vivo, indicating their potential for nerve restoration.

BIOFABRICATION (2022)

Review Chemistry, Multidisciplinary

Poly(3,4-ethylenedioxythiophene)-Based Neural Interfaces for Recording and Stimulation: Fundamental Aspects and In Vivo Applications

Michele Bianchi et al.

Summary: Researchers in the fields of neuroscience, materials science, and nanotechnology are working together to design and manufacture neural interfaces that enable bidirectional communication with the central nervous system. Conductive polymers are attractive materials for sensing/stimulating electrodes due to their unique properties. This review focuses on the latest advancements in poly(3,4-ethylenedioxythiophene)-based neural interfaces for extracellular recording and stimulation, highlighting the most reliable solutions and identifying future trends in the field.

ADVANCED SCIENCE (2022)

Article Nanoscience & Nanotechnology

Cross-Linked γ-Polyglutamic Acid as an Aqueous SiOx Anode Binder for Long-Term Lithium-Ion Batteries

Huayan Xiao et al.

Summary: In this study, an aqueous binder called PGA-ECH was used to enhance the performance of SiOx anodes, improving long-term cycling stability. The binder's structure contains abundant functional groups that form strong interactions with the SiOx surface, ensuring good interfacial adhesion. Covalent bonds and supramolecular interactions in the binder guarantee mechanical strength and elasticity. The interactions between lithium ions and the oxygen (nitrogen) atoms of carboxylate (peptide) bonds facilitate the diffusion of lithium ions.

ACS APPLIED MATERIALS & INTERFACES (2022)

Article Biophysics

In situ polymerization of conducting polymers around living neural cells: Cellular effect study

Hai-lan Chen et al.

Summary: This study investigated the immediate and long-term cellular response to in-situ polymerization of conductive polymers by directly polymerizing them around living neural cells. The experimental findings provide information on the feasibility of this technique in practical applications.

COLLOIDS AND SURFACES B-BIOINTERFACES (2022)

Review Audiology & Speech-Language Pathology

Cochlear implants: Causes, effects and mitigation strategies for the foreign body response and inflammation

Muhammad T. Rahman et al.

Summary: Cochlear implants provide effective auditory rehabilitation for patients with severe to profound sensorineural hearing loss. This article reviews the impact of the inflammatory/foreign body response (FBR) on cochlear implants, the factors affecting the response, and therapeutic strategies to mitigate it. The understanding of the FBR has the potential to improve current cochlear implants and facilitate the development of neural prostheses.

HEARING RESEARCH (2022)

Article Materials Science, Biomaterials

3D-Printed Polypyrrole Microneedle Arrays for Electronically Controlled Transdural Drug Release

Joyce Huang et al.

Summary: After spinal cord injury, inflammation and cytotoxicity cause further damage to neural cells. Research has found that the progression of this secondary injury can be reduced by administering anti-inflammatory drugs through a microneedle array for local delivery.

ACS BIOMATERIALS SCIENCE & ENGINEERING (2022)

Article Engineering, Biomedical

ROS-responsive polymer nanoparticles with enhanced loading of dexamethasone effectively modulate the lung injury microenvironment

Wali Muhammad et al.

Summary: Acute lung injury (ALI) is an inflammatory disorder associated with cytokine storm, and there is an urgent need for medication and effective drug delivery to reduce inflammation. The study found that PFTU@DEX NPs can effectively suppress inflammatory cells, ROS signaling pathways, and cell apoptosis to ameliorate ALI.

ACTA BIOMATERIALIA (2022)

Review Clinical Neurology

Deep brain stimulation of the subthalamic nucleus for epilepsy

Hao Yan et al.

Summary: Deep brain stimulation of the subthalamic nucleus (STN-DBS) is a promising palliative option for patients with refractory epilepsy. However, crucial questions remain unanswered regarding patient selection, stimulation parameters, and the mechanisms of action of STN-DBS. This review summarizes the clinical evidence, safety profile, and factors influencing stimulation outcomes of STN-DBS, providing guidance for clinical decision-making. Future research directions are also suggested based on the current knowledge.

ACTA NEUROLOGICA SCANDINAVICA (2022)

Review Engineering, Biomedical

Polymeric Nanofibers for Drug Delivery Applications: A Recent Review

Xiaoge Duan et al.

Summary: Polymer nanofibers are promising materials for drug delivery systems, offering advantages such as easy preparation, adjustable properties, and controllable release kinetics. They have a wide range of applications in drug delivery due to their physiochemical properties.

JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE (2022)

Article Nanoscience & Nanotechnology

Nanostructured PEDOT Coatings for Electrode-Neuron Integration

Ziyi Zhang et al.

Summary: In this study, a nanostructured PEDOT coating with long protrusions was successfully created via a one-step electrochemical polymerization method, enhancing the active surface area of the electrode. The PEDOT-modified microelectrodes exhibited low impedance and large charge storage capacity density, while also showing good biocompatibility, indicating their potential as an electroactive and biosafe contact between implanted neural electrodes and neurons.

ACS APPLIED BIO MATERIALS (2021)

Review Engineering, Biomedical

Soft and Ion-Conducting Materials in Bioelectronics: From Conducting Polymers to Hydrogels

Manping Jia et al.

ADVANCED HEALTHCARE MATERIALS (2020)

Review Biochemistry & Molecular Biology

Emerging Modalities and Implantable Technologies for Neuromodulation

Sang Min Won et al.

Article Biochemistry & Molecular Biology

Antioxidant and gastrointestinal cytoprotective effect of edible polypeptide poly-γ-glutamic acid

Jong Min Lee et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2020)

Article Nanoscience & Nanotechnology

On-Site Colorimetric Detection of Cholesterol Based on Polypyrrole Nanoparticles

Chengyi Hong et al.

ACS APPLIED MATERIALS & INTERFACES (2020)

Article Biophysics

Micro- and nanotechnology for neural electrode-tissue interfaces

Shuangjie Liu et al.

BIOSENSORS & BIOELECTRONICS (2020)

Review Biotechnology & Applied Microbiology

Dexamethasone-Enhanced Microdialysis and Penetration Injury

Andrea Jaquins-Gerstl et al.

FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY (2020)

Article Chemistry, Multidisciplinary

Soft and MRI Compatible Neural Electrodes from Carbon Nanotube Fibers

Linlin Lu et al.

NANO LETTERS (2019)

Review Engineering, Biomedical

A Critical Review of Microelectrode Arrays and Strategies for Improving Neural Interfaces

Morgan Ferguson et al.

ADVANCED HEALTHCARE MATERIALS (2019)

Review Chemistry, Multidisciplinary

Recent Advances in Materials, Devices, and Systems for Neural Interfaces

Sang Min Won et al.

ADVANCED MATERIALS (2018)

Article Materials Science, Biomaterials

Promotion of neurite outgrowth by rationally designed NGF-β binding peptide nanofibers

Zeynep Okur et al.

BIOMATERIALS SCIENCE (2018)

Article Medicine, Research & Experimental

Nerve growth factor carbon nanotube complex exerts prolonged protective effects in an in vitro model of ischemic stroke

Parichehr Hassanzadeh et al.

LIFE SCIENCES (2017)

Review Engineering, Biomedical

Glial responses to implanted electrodes in the brain

Joseph W. Salatino et al.

NATURE BIOMEDICAL ENGINEERING (2017)

Review Chemistry, Multidisciplinary

Conducting Polymers for Neural Prosthetic and Neural Interface Applications

Rylie Green et al.

ADVANCED MATERIALS (2015)

Review Neurosciences

Revealing neuronal function through microelectrode array recordings

Marie Engelene J. Obien et al.

FRONTIERS IN NEUROSCIENCE (2015)

Article Engineering, Biomedical

Controlled release of dexamethasone from peptide nanofiber gels to modulate inflammatory response

Matthew J. Webber et al.

BIOMATERIALS (2012)

Article Nanoscience & Nanotechnology

Quantitative Control of Neuron Adhesion at a Neural Interface Using a Conducting Polymer Composite with Low Electrical Impedance

Sung Yeol Kim et al.

ACS APPLIED MATERIALS & INTERFACES (2011)

Article Engineering, Biomedical

Carbon nanotube nanoreservior for controlled release of anti-inflammatory dexamethasone

Xiliang Luo et al.

BIOMATERIALS (2011)

Article Nanoscience & Nanotechnology

Stimulation of neuronal neurite outgrowth using functionalized carbon nanotubes

K. Matsumoto et al.

NANOTECHNOLOGY (2010)

Article Nanoscience & Nanotechnology

A mesoporous silica nanosphere-based drug delivery system using an electrically conducting polymer

Youngnam Cho et al.

NANOTECHNOLOGY (2009)

Article Chemistry, Multidisciplinary

Effect of immobilized nerve growth factor on conductive polymers: Electrical properties and cellular response

Dong-Hwan Kim et al.

ADVANCED FUNCTIONAL MATERIALS (2007)

Article Chemistry, Multidisciplinary

Electrochemically controlled release of dexamethasone from conducting polymer polypyrrole coated electrode

R Wadhwa et al.

JOURNAL OF CONTROLLED RELEASE (2006)