4.7 Article

Characterization of a novel species-specific 51-amino acid peptide, PEP51, as a caspase-3/7 activator in ovarian follicles of the ascidian, Ciona intestinalis Type A

Related references

Note: Only part of the references are listed.
Article Anatomy & Morphology

Distribution changes of non-self-test cells and self-tunic cells surrounding the outer body during Ciona metamorphosis

Nozomu M. Totsuka et al.

Summary: Ascidians undergo metamorphosis to change their body structure, and the dynamics of cell distribution during this process has been unclear. However, this study found that mesenchymal cells extravasate following Ca2+ transients, and the distribution of test cells and tunic cells changed during metamorphosis.

DEVELOPMENTAL DYNAMICS (2023)

Article Endocrinology & Metabolism

Kobayashi Award 2021: Neuropeptides, receptors, and follicle development in the ascidian, Ciona intestinalis Type A: New clues to the evolution of chordate neuropeptidergic systems from biological niches

Honoo Satake

Summary: Ciona intestinalis Type A is a cosmopolitan species that is closely related to vertebrates, making it a valuable model for studying the evolution and comparative physiology of endocrine, neuroendocrine, and nervous systems in chordates. Through peptidomic approaches and reference to genome sequences, our group has identified over 30 Ciona neuropeptides and their receptors. Some of these neuropeptides have been found to play significant roles in the regulation of ovarian follicle development.

GENERAL AND COMPARATIVE ENDOCRINOLOGY (2023)

Review Neurosciences

A Review on Caspases: Key Regulators of Biological Activities and Apoptosis

Gayatri Sahoo et al.

Summary: Caspases are proteolytic enzymes that play a crucial role in homeostasis and programmed cell death. They have been classified based on their roles in apoptosis and inflammation, as well as their mechanism of action. Caspases are also involved in non-apoptotic cell death processes such as necroptosis, pyroptosis, and autophagy.

MOLECULAR NEUROBIOLOGY (2023)

Review Cell Biology

cAMP signaling in ovarian physiology in teleosts: A review

Takayuki Takahashi et al.

Summary: Ovarian function in teleosts is regulated by gonadotropins FSH and LH, which activate membrane-bound G protein-coupled receptors on follicle cells, leading to increased intracellular cAMP signaling. FSH promotes vitellogenesis through 17 beta-estradiol production in growing follicles, while LH induces meiotic resumption and ovulation in fully grown post-vitellogenic follicles. This review summarizes the role of the cAMP pathway in gonadotropin-induced processes and discusses the differences and similarities between mammalian and teleost cAMP signaling pathways.

CELLULAR SIGNALLING (2023)

Review Endocrinology & Metabolism

Omics Studies for the Identification of Ascidian Peptides, Cognate Receptors, and Their Relevant Roles in Ovarian Follicular Development

Tsuyoshi Kawada et al.

Summary: Omics studies, including mass spectrometry-based peptidomic studies, have contributed to the understanding of genomes, gene expressions, and gene functions. In the ascidian Ciona intestinalis Type A, these studies have detected specific neuropeptides and homologs of vertebrate neuropeptides and hypothalamic peptide hormones. Furthermore, through transcriptome analysis and machine learning, candidate G protein-coupled receptors (GPCRs) for these peptides have been identified. The comparative transcriptomics and peptide treatment experiments have provided insights into the biological functions and regulatory mechanisms of specific peptides in Ciona follicular development and growth.

FRONTIERS IN ENDOCRINOLOGY (2022)

Review Cell Biology

Paradoxical roles of caspase-3 in regulating cell survival, proliferation, and tumorigenesis

Ebrahim Eskandari et al.

Summary: Caspase-3 plays a crucial role in apoptosis and is involved in the growth and maintenance of both normal and malignant cells. Understanding its evolution and dichotomous roles can provide insights into the biology of malignant and normal cells.

JOURNAL OF CELL BIOLOGY (2022)

Article Endocrinology & Metabolism

Vasopressin Promoter Transgenic and Vasopressin Gene-Edited Ascidian, Ciona intestinalis Type A (Ciona robusta): Innervation, Gene Expression Profiles, and Phenotypes

Tsuyoshi Kawada et al.

Summary: The neuropeptides oxytocin and vasopressin are found in a wide range of vertebrates and invertebrates. In the ascidian Ciona intestinalis Type A, a vasopressin-related peptide called CiVP was identified, which plays a role in inducing oocyte maturation and ovulation. Through genetic modification of Ciona, it was found that CiVP is highly expressed in the cerebral ganglion and nerve tissues, and mutants lacking CiVP showed altered ovarian follicle growth and gene expression related to ovarian function. This study represents the first report of a vasopressin gene being studied in an invertebrate species, shedding light on its roles in biological processes.

FRONTIERS IN ENDOCRINOLOGY (2021)

Article Multidisciplinary Sciences

Cionin, a vertebrate cholecystokinin/gastrin homolog, induces ovulation in the ascidian Ciona intestinalis type A

Tomohiro Osugi et al.

Summary: This study reveals the biological role of cionin in regulating ovulation, demonstrating that it induces ovulation by stimulating MMP gene expression via the RTK signaling pathway. This is the first report on the endogenous roles of cionin and the induction of ovulation by cholecystokinin/gastrin family peptides in an organism.

SCIENTIFIC REPORTS (2021)

Review Obstetrics & Gynecology

The role of pituitary gonadotropins and intraovarian regulators in follicle development: A mini-review

Makoto Orisaka et al.

Summary: This review outlines recent findings on the mechanisms of human follicle development, highlighting the roles of pituitary gonadotropins and intraovarian regulators. The study discusses the involvement of signaling pathways and hormones in different stages of follicle development, as well as the essential factors for antral follicle maturation.

REPRODUCTIVE MEDICINE AND BIOLOGY (2021)

Review Biochemistry & Molecular Biology

Invertebrate Gonadotropin-Releasing Hormone Receptor Signaling and Its Relevant Biological Actions

Tsubasa Sakai et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)

Article Multidisciplinary Sciences

Repertoires of G protein-coupled receptors for Ciona-specific neuropeptides

Akira Shiraishi et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)

Review Endocrinology & Metabolism

Ovulation: Parallels With Inflammatory Processes

Diane M. Duffy et al.

ENDOCRINE REVIEWS (2019)

Review Developmental Biology

Follicle rupture during ovulation with an emphasis on recent progress in fish models

Takayuki Takahashi et al.

REPRODUCTION (2019)

Review Endocrinology & Metabolism

Coordination of Ovulation and Oocyte Maturation: A Good Egg at the Right Time

Rebecca L. Robker et al.

ENDOCRINOLOGY (2018)

Review Endocrinology & Metabolism

Invertebrate Gonadotropin-Releasing Hormone-Related Peptides and Their Receptors: An Update

Tsubasa Sakai et al.

FRONTIERS IN ENDOCRINOLOGY (2017)

Review Biochemistry & Molecular Biology

Killers creating new life: caspases drive apoptosis-induced proliferation in tissue repair and disease

Caitlin E. Fogarty et al.

CELL DEATH AND DIFFERENTIATION (2017)

Review Biology

Chordate evolution and the three-phylum system

Noriyuki Satoh et al.

PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES (2014)

Article Cell Biology

Developmental Control of Oocyte Maturation and Egg Activation in Metazoan Models

Jessica R. Von Stetina et al.

COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2011)

Review Endocrinology & Metabolism

The Mammalian Ovary from Genesis to Revelation

Mark A. Edson et al.

ENDOCRINE REVIEWS (2009)

Article Multidisciplinary Sciences

Topological Control of Life and Death in Non-Proliferative Epithelia

Camille Martinand-Mari et al.

PLOS ONE (2009)

Article Developmental Biology

Regulatory roles of nitric oxide during larval development and metamorphosis in Ciona intestinalis

Stefania Comes et al.

DEVELOPMENTAL BIOLOGY (2007)

Article Developmental Biology

Establishment of animal-vegetal polarity during maturation in ascidian oocytes

F Prodon et al.

DEVELOPMENTAL BIOLOGY (2006)