Enhanced recovery in patients with gestational diabetes mellitus and MTHFR 677 TT genotype after taking high-dose folic acid supplements during mid-late pregnancy: an open-label interventional study

Review Obstetrics & Gynecology

Increasing prevalence of gestational diabetes mellitus when carrying the T variant allele of the MTHFR gene C677T polymorphism: a systematic review and meta-analysis

Yanjie Chen et al.

Summary: A meta-analysis on the relationship between MTHFR gene polymorphisms and gestational diabetes risk revealed that the T allele of the C677T polymorphism may increase susceptibility to gestational diabetes in Asians, while the A1298C polymorphism is not associated with an increased risk of this disorder.

ARCHIVES OF GYNECOLOGY AND OBSTETRICS (2022)

Add to Collection

Article Endocrinology & Metabolism

15. Management of Diabetes in Pregnancy: Standards of Medical Care in Diabetes-2022

Summary: The American Diabetes Association (ADA) Standards of Medical Care in Diabetes provides guidelines and tools for diabetes care and evaluation of quality of care. The standards are updated by a multidisciplinary expert committee.

DIABETES CARE (2022)

Add to Collection

Review Endocrinology & Metabolism

Lifestyle interventions in pregnancy targeting GDM prevention: looking ahead to precision medicine

Joshua R. Sparks et al.

Summary: GDM prevention strategies have had mixed results, but recent research indicates that lifestyle interventions before pregnancy may be more effective. Precision prevention, tailoring interventions based on individual-level risk factors, is crucial for future studies to prevent GDM effectively. Adapting interventions in real-time based on individual responses could also be beneficial for future interventions.

DIABETOLOGIA (2022)

Add to Collection

Article Multidisciplinary Sciences

Association between folic acid use during pregnancy and gestational diabetes mellitus: Two population-based Nordic cohort studies

Laura Pazzagli et al.

Summary: This study aimed to estimate the association between folic acid use during pregnancy and risk of gestational diabetes mellitus (GDM) in two population-based Nordic cohorts. The results showed that self-reported folic acid use had slightly higher or lower odds for GDM in Norway and Sweden respectively, which are not clinically significant. However, prescribed folic acid use had higher odds for GDM, likely due to the specific comorbidities and co-medications of the women using it. Therefore, the recommendations for folic acid use in pregnancy should remain unchanged.

PLOS ONE (2022)

Add to Collection

Article Nutrition & Dietetics

Association of Folic Acid Supplementation in Early Pregnancy with Risk of Gestational Diabetes Mellitus: A Longitudinal Study

Hongyan Chen et al.

Summary: This study found that folic acid supplementation may be a protective factor for the risk of GDM caused by high postprandial blood glucose.

NUTRIENTS (2022)

Add to Collection

Article Multidisciplinary Sciences

Association of pre- and early-pregnancy factors with the risk for gestational diabetes mellitus in a large Chinese population

Min Zhao et al.

Summary: The study identified eight independent pre-/early-pregnancy predictors significantly associated with later GDM risk and the nomogram model established had over 85% accuracy in early detecting pregnant women who will progress to GDM later.

SCIENTIFIC REPORTS (2021)

Add to Collection

Article Endocrinology & Metabolism