Case Report: Abruptio placentae and epileptic seizure after occurrence of perinatal hyperglycaemia in woman with gestational diabetes mellitus and hypertriglyceridemia-induced acute pancreatitis

Hypertriglyceridemia-induced acute pancreatitis seldom occurs in the second trimester of pregnancy with gestational diabetes mellitus. For these patients, the existing knowledge on concomitant hyperglycemia is not sufficient. We report a case of abruptio placentae and epileptic seizure following perinatal hyperglycaemia in woman with gestational diabetes mellitus and hypertriglyceridemia-induced acute pancreatitis. The occurrence of abruptio placentae and epileptic seizure may be associated with concomitant hyperglycemia, and the epileptic seizure was terminated after she underwent treatment with insulin. We should pay more attention to the adverse effects of perinatal hyperglycemia and continue to give appropriate insulin treatment even if patients have passed the acute phase of hypertriglyceridemia-induced acute pancreatitis.

Automated summary

Hypertriglyceridemia-induced acute pancreatitis rarely occurs in the second trimester of pregnancy with gestational diabetes mellitus. This case report presents a case of abruptio placentae and epileptic seizure in a woman with gestational diabetes mellitus and hypertriglyceridemia-induced acute pancreatitis, suggesting that the occurrence of epileptic seizure may be associated with concomitant hyperglycemia and can be terminated with insulin treatment.