Journal
NATURAL PRODUCT RESEARCH
Volume 30, Issue 21, Pages 2407-2412Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1080/14786419.2016.1190722
Keywords
Helvolic acid methyl ester; endophytic fungus; Fusarium sp; Ficus carica; antifungal activity
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Funding
- Specialized Research Fund for the Doctoral Program of Higher Education of china [20116125110001]
- Natural Science Basic Research Plan in Shaanxi Province of China [2014JZ003]
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A new helvolic acid derivative named helvolic acid methyl ester (1), together with two known helvolic acid compounds, helvolic acid (2) and hydrohelvolic acid (3), were isolated from the fermentation of endophytic fungus Fusarium sp. in Ficus carica leaves. Their structures were elucidated and identified by spectroscopic methods. Compounds 1-3 showed potent antifungal and antibacterial activities. [GRAPHICS] .
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