Journal
INFLAMMOPHARMACOLOGY
Volume -, Issue -, Pages -Publisher
SPRINGER BASEL AG
DOI: 10.1007/s10787-023-01304-y
Keywords
Narcotics; Pain; Opium; Heroin; Morphine; Codeine
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Opium derived products have been used in ancient civilizations including Assyrians, Egyptians, Romans, and Greeks. Morphine was isolated from raw opium in the early 19th century and was named after the Greek God of dreams, Morpheus. Opioid products have therapeutic value for pain management in various medical conditions.
There is documentation of the use of opium derived products in the ancient history of the Assyrians: the Egyptians; in the sixth century AD by the Roman Dioscorides; and by Avicenna (980-1037). Reference to opium like products is made by Paracelsus and by Shakespeare. Charles Louis Derosne and Fredrich Wilhelm Adam Serturner isolated morphine from raw opium in 1802 and 1806 respectively, and it was Serturner who named the substance morphine, after Morpheus, the Greek God of dreams. By the middle 1800s, Opium and related opioid derived products were the source of a major addiction in USA, and to some extent in the United Kingdom. Opioid products are of major therapeutic value in the treatment of pain from injury, post surgery, intractable pain conditions, and some forms of terminal cancer.
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