Journal
NATURAL PRODUCT RESEARCH
Volume 30, Issue 15, Pages 1706-1711Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1080/14786419.2015.1136888
Keywords
Talaromyces sp; endophytic fungi; dimeric anthraquinone; skyrin
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Funding
- National Natural Science Foundation of China [81460545]
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A new unsymmetrical dimeric anthraquinone, 3-demethyl-3-(2-hydroxypropyl)-skyrin (1) was isolated from the solid-state fermentation extract of an endophytic fungal strain Talaromyces sp. YE 3016, together with five known compounds, skyrin (2), oxyskyrin (3), emodin (4), 1,3,6-trihydroxy-8-methyl-anthraquinone (5) and ergosterol (6). The structure of the new compound was elucidated on the basis of spectroscopic analysis. Compounds 1-3 exhibited moderate cytotoxic activities against MCF-7 cell line. [GRAPHICS] .
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