Journal
NATURAL PRODUCT RESEARCH
Volume 30, Issue 14, Pages 1639-1645Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1080/14786419.2015.1129334
Keywords
Euphorbia dracunculoides; diterpenoids; hydroperoxy; tigliane
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Funding
- Natural Science Foundation of China (NSFC) [31160075, 21362035]
- Initial Foundation of Scientific Research for the introduction of talents from Southwest Forestry University for Wen-Hui Xu [20130916]
- Sci-tech Innovation Foundation of Southwest Forestry University [C1478]
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One new tigliane-type diterpene, 4-deoxy-4(beta)H-8-hydroperoxyphorbol-12-benzoate-13-isobutyrate (1), together with two known diterpenoids, 3-acetyl-5,8-dibenzoyl-14 alpha-propanoyl-13,17-epoxy-7-myrsinaone diterpene with C9-C10 cyclised to form an additional lactone ring (2), Euphodendriane A (3) have been isolated from the whole plants of Euphorbia dracunculoides Lam. Their structures were elucidated by means of extensive spectroscopic analysis (NMR and HR-ESI-MS) and comparison with data reported in the literature. This is the first isolation of 8-hydroperoxy tigliane diterpene (1) from the genus of Euphorbia. All compounds were evaluated for their antifungal activities. [GRAPHICS] .
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