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Intestinal factors promoting the development of RORγt+ cells and oral tolerance

FRONTIERS IN IMMUNOLOGY (2023)

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R. Sharon Chinthrajah et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2016)

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Article Allergy

Regulatory T cells in allergic diseases

Magali Noval Rivas et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2016)

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Article Allergy

Early-life gut microbiome composition and milk allergy resolution

Supinda Bunyavanich et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2016)

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Article Immunology

Vitamin A Controls the Presence of RORγ+ Innate Lymphoid Cells and Lymphoid Tissue in the Small Intestine

Gera Goverse et al.

JOURNAL OF IMMUNOLOGY (2016)

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Article Immunology

Antigen-Specific Development of Mucosal Foxp3+RORγt+ T Cells from Regulatory T Cell Precursors

Benjamin D. Solomon et al.

JOURNAL OF IMMUNOLOGY (2016)

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Article Immunology

Classical dendritic cells are required for dietary antigen-mediated induction of peripheral Treg cells and tolerance

Daria Esterhazy et al.

NATURE IMMUNOLOGY (2016)

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Article Biochemistry & Molecular Biology

An asthma-associated IL4R variant exacerbates airway inflammation by promoting conversion of regulatory T cells to TH17-like cells

Amir Hossein Massoud et al.

NATURE MEDICINE (2016)

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Article Multidisciplinary Sciences

Dietary antigens limit mucosal immunity by inducing regulatory T cells in the small intestine

Kwang Soon Kim et al.

SCIENCE (2016)

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Article Multidisciplinary Sciences

Tissue adaptation of regulatory and intraepithelial CD4+ T cells controls gut inflammation

Tomohisa Sujino et al.

SCIENCE (2016)

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Review Immunology

Tolerance to the Intestinal Microbiota Mediated by ROR(γt)+ Cells

Caspar Ohnmacht

TRENDS IN IMMUNOLOGY (2016)

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Review Immunology

AHR Function in Lymphocytes: Emerging Concepts

Liang Zhou

TRENDS IN IMMUNOLOGY (2016)

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Article Cell Biology

Dietary Fiber and Bacterial SCFA Enhance Oral Tolerance and Protect against Food Allergy through Diverse Cellular Pathways

Jian Tan et al.

CELL REPORTS (2016)

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Article Cell Biology

Rapid and Efficient Generation of Regulatory T Cells to Commensal Antigens in the Periphery

Katherine Nutsch et al.

CELL REPORTS (2016)

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Article Immunology

Smad2 and Smad3 Inversely Regulate TGF-β Autoinduction in Clostridium butyricum-Activated Dendritic Cells

Ikkou Kashiwagi et al.

IMMUNITY (2015)

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Article Immunology

Retinoic Acid Differentially Regulates the Migration of Innate Lymphoid Cell Subsets to the Gut

Myung H. Kim et al.

IMMUNITY (2015)

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Article Immunology

MyD88 Adaptor-Dependent Microbial Sensing by Regulatory T Cells Promotes Mucosal Tolerance and Enforces Commensalism

Sen Wang et al.

IMMUNITY (2015)

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Article Immunology

Regulatory T Cell Reprogramming toward a Th2-Cell-like Lineage Impairs Oral Tolerance and Promotes Food Allergy

Magali Noval Rivas et al.

IMMUNITY (2015)

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Article Biochemistry & Molecular Biology

Inhibition of mechanical allodynia in neuropathic pain by TLR5-mediated A-fiber blockade

Zhen-Zhong Xu et al.

NATURE MEDICINE (2015)

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Article Multidisciplinary Sciences

Retinoic Acid Can Exacerbate T Cell Intrinsic TLR2 Activation to Promote Tolerance

Vivien Nguyen et al.

PLOS ONE (2015)

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Article Multidisciplinary Sciences

The microbiota regulates type 2 immunity through RORγt+ T cells

Caspar Ohnmacht et al.

SCIENCE (2015)

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Article Multidisciplinary Sciences

Individual intestinal symbionts induce a distinct population of RORγ+ regulatory T cells

Esen Sefik et al.

SCIENCE (2015)

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Article Multidisciplinary Sciences

Group 3 innate lymphoid cells mediate intestinal selection of commensal bacteria-specific CD4+ T cells

Matthew R. Hepworth et al.

SCIENCE (2015)

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Review Immunology

Notch in T Cell Differentiation: All Things Considered

Derk Amsen et al.

TRENDS IN IMMUNOLOGY (2015)

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Editorial Material Oncology

Situational aldehyde dehydrogenase expression by regulatory T cells may explain the contextual duality of cyclophosphamide as both a pro-inflammatory and tolerogenic agent

Christopher G. Kanakry et al.

ONCOIMMUNOLOGY (2015)

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Article Immunology

Retinoic acid primes human dendritic cells to induce gut-homing, IL-10-producing regulatory T cells

G. Bakdash et al.

MUCOSAL IMMUNOLOGY (2015)

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Article Immunology

Microbial sensing by goblet cells controls immune surveillance of luminal antigens in the colon

K. A. Knoop et al.

MUCOSAL IMMUNOLOGY (2015)

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Article Pharmacology & Pharmacy

All-trans retinoic acid regulates hepatic bile acid homeostasis

Fan Yang et al.

BIOCHEMICAL PHARMACOLOGY (2014)

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Article Allergy

The regulatory T cells induction by epicutaneous immunotherapy is sustained and mediates long-term protection from eosinophilic disorders in peanut-sensitized mice

V. Dioszeghy et al.

CLINICAL AND EXPERIMENTAL ALLERGY (2014)

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Article Immunology

Immunoglobulin E Signal Inhibition during Allergen Ingestion Leads to Reversal of Established Food Allergy and Induction of Regulatory T Cells

Oliver T. Burton et al.

IMMUNITY (2014)

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Article Immunology

Activation of Gpr109a, Receptor for Niacin and the Commensal Metabolite Butyrate, Suppresses Colonic Inflammation and Carcinogenesis

Nagendra Singh et al.

IMMUNITY (2014)

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Article Immunology

Interleukin-22 binding protein (IL-22BP) is constitutively expressed by a subset of conventional dendritic cells and is strongly induced by retinoic acid

J. C. J. Martin et al.

MUCOSAL IMMUNOLOGY (2014)

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Article Multidisciplinary Sciences

Maternal retinoids control type 3 innate lymphoid cells and set the offspring immunity

Serge A. van de Pavert et al.

NATURE (2014)

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Article Multidisciplinary Sciences

A Systematic Review on the Development of Asthma and Allergic Diseases in Relation to International Immigration: The Leading Role of the Environment Confirmed

Baltica Cabieses et al.

PLOS ONE (2014)

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Article Multidisciplinary Sciences

Commensal bacteria protect against food allergen sensitization

Andrew T. Stefka et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)

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Article Multidisciplinary Sciences

Microbiota-Dependent Crosstalk Between Macrophages and ILC3 Promotes Intestinal Homeostasis

Arthur Mortha et al.

SCIENCE (2014)

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Article Multidisciplinary Sciences

Adaptation of Innate Lymphoid Cells to a Micronutrient Deficiency Promotes Type 2 Barrier Immunity

S. P. Spencer et al.

SCIENCE (2014)

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Article Cell Biology

Regulatory T Cells Occupy an Isolated Niche in the Intestine that Is Antigen Independent

Lisa L. Korn et al.

CELL REPORTS (2014)

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Article Gastroenterology & Hepatology

Characterization of the 17 strains of regulatory T cell-inducing human-derived Clostridia

Seiko Narushima et al.

GUT MICROBES (2014)

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Article Microbiology

Intestinal Microbial Diversity during Early-Life Colonization Shapes Long-Term IgE Levels

Julia Cahenzli et al.

CELL HOST & MICROBE (2013)

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Article Immunology

Egr-2 transcription factor is required for Blimp-1-mediated IL-10 production in IL-27-stimulated CD4+ T cells

Yukiko Iwasaki et al.

EUROPEAN JOURNAL OF IMMUNOLOGY (2013)

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Article Allergy

A microbiota signature associated with experimental food allergy promotes allergic sensitization and anaphylaxis

Magali Noval Rivas et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2013)

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Article Immunology

Retinoic acid expression associates with enhanced IL-22 production by γδ T cells and innate lymphoid cells and attenuation of intestinal inflammation

Lisa A. Mielke et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2013)

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Article Immunology

IL-4 and Retinoic Acid Synergistically Induce Regulatory Dendritic Cells Expressing Aldh1a2

Bing Zhu et al.

JOURNAL OF IMMUNOLOGY (2013)

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Article Immunology

OX40L/Jagged1 Cosignaling by GM-CSF-Induced Bone Marrow-Derived Dendritic Cells Is Required for the Expansion of Functional Regulatory T Cells

Anupama Gopisetty et al.

JOURNAL OF IMMUNOLOGY (2013)

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Article Immunology

Potential autocrine regulation of interleukin-33/ST2 signaling of dendritic cells in allergic inflammation

Z. Su et al.

MUCOSAL IMMUNOLOGY (2013)

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Article Multidisciplinary Sciences

Commensal microbe-derived butyrate induces the differentiation of colonic regulatory T cells

Yukihiro Furusawa et al.

NATURE (2013)

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Article Multidisciplinary Sciences

Metabolites produced by commensal bacteria promote peripheral regulatory T-cell generation

Nicholas Arpaia et al.

NATURE (2013)

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Bacteria activate sensory neurons that modulate pain and inflammation

Isaac M. Chiu et al.

NATURE (2013)

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Article Multidisciplinary Sciences

Thymus-derived regulatory T cells contribute to tolerance to commensal microbiota

Anna Cebula et al.

NATURE (2013)

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Treg induction by a rationally selected mixture of Clostridia strains from the human microbiota

Koji Atarashi et al.

NATURE (2013)

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The Microbial Metabolites, Short-Chain Fatty Acids, Regulate Colonic Treg Cell Homeostasis

Patrick M. Smith et al.

SCIENCE (2013)

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Article Multidisciplinary Sciences

Mucus Enhances Gut Homeostasis and Oral Tolerance by Delivering Immunoregulatory Signals

Meimei Shan et al.

SCIENCE (2013)

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Review Immunology

Dietary inhibitors of histone deacetylases in intestinal immunity anc homeostasis

R. Schilderink et al.

FRONTIERS IN IMMUNOLOGY (2013)

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Article Immunology

Indoleamine 2,3-Dioxygenase and Dendritic Cell Tolerogenicity

Jamie L. Harden et al.

IMMUNOLOGICAL INVESTIGATIONS (2012)

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Article Medicine, Research & Experimental

MyD88 is critically involved in immune tolerance breakdown at environmental interfaces of Foxp3-deficient mice

Magali Noval Rivas et al.

JOURNAL OF CLINICAL INVESTIGATION (2012)

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Article Immunology

Neuropilin 1 is expressed on thymus-derived natural regulatory T cells, but not mucosa- generated induced Foxp3+ T reg cells

Jonathan M. Weiss et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2012)

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Article Gastroenterology & Hepatology

MyD88 and Retinoic Acid Signaling Pathways Interact to Modulate Gastrointestinal Activities of Dendritic Cells

Eduardo J. Villablanca et al.

GASTROENTEROLOGY (2011)

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Article Immunology

Intestinal Tolerance Requires Gut Homing and Expansion of FoxP3+ Regulatory T Cells in the Lamina Propria

Usriansyah Hadis et al.

IMMUNITY (2011)

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Article Immunology

Interleukin-10 Signaling in Regulatory T Cells Is Required for Suppression of Th17 Cell-Mediated Inflammation

Ashutosh Chaudhry et al.

IMMUNITY (2011)

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Article Immunology

MyD88-Dependent TLR1/2 Signals Educate Dendritic Cells with Gut-Specific Imprinting Properties

Sen Wang et al.

JOURNAL OF IMMUNOLOGY (2011)

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Article Multidisciplinary Sciences

Peripheral education of the immune system by colonic commensal microbiota

Stephanie K. Lathrop et al.

NATURE (2011)

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Induction of Colonic Regulatory T Cells by Indigenous Clostridium Species

Koji Atarashi et al.

SCIENCE (2011)

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The Toll-Like Receptor 2 Pathway Establishes Colonization by a Commensal of the Human Microbiota

June L. Round et al.

SCIENCE (2011)

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Article Toxicology

Activation of the Aryl Hydrocarbon Receptor Suppresses Sensitization in a Mouse Peanut Allergy Model

V. J. Schulz et al.

TOXICOLOGICAL SCIENCES (2011)

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Article Immunology

Generation of Mucosal Dendritic Cells from Bone Marrow Reveals a Critical Role of Retinoic Acid

Ting Feng et al.

JOURNAL OF IMMUNOLOGY (2010)

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Article Multidisciplinary Sciences

Inducible Foxp3+ regulatory T-cell development by a commensal bacterium of the intestinal microbiota

June L. Round et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)

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Article Multidisciplinary Sciences

Conversion of Th2 memory cells into Foxp3+ regulatory T cells suppressing Th2-mediated allergic asthma

Byung-Seok Kim et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)

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Letter Immunology

Retinoic Acid Can Directly Promote TGF-β-Mediated Foxp3+ Treg Cell Conversion of Naive T Cells Response to Letter from Mucida et al.

Jonathan A. Hill et al.

IMMUNITY (2009)

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Letter Immunology

Retinoic Acid Can Directly Promote TGF-β-Mediated Foxp3+ Treg Cell Conversion of Naive T Cells

Daniel Mucida et al.

IMMUNITY (2009)

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Article Immunology

Nuclear Factor-κB Modulates Regulatory T Cell Development by Directly Regulating Expression of Foxp3 Transcription Factor

Meixiao Long et al.

IMMUNITY (2009)

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Article Immunology

The contribution of direct TLR signaling to T cell responses

Adeeb H. Rahman et al.

IMMUNOLOGIC RESEARCH (2009)

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Article Immunology

GM-CSF and IL-4 synergistically trigger dendritic cells to acquire retinoic acid-producing capacity

Aya Yokota et al.

INTERNATIONAL IMMUNOLOGY (2009)

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Article Immunology

Retinoic acid can enhance conversion of naive into regulatory T cells independently of secreted cytokines

Jens Nolting et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2009)

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Article Immunology

Contrasting roles for all-trans retinoic acid in TGF-β-mediated induction of Foxp3 and Il10 genes in developing regulatory T cells

Craig L. Maynard et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2009)

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Article Immunology

Constitutive Expression of IDO by Dendritic Cells of Mesenteric Lymph Nodes: Functional Involvement of the CTLA-4/B7 and CCL22/CCR4 Interactions

Toshiharu Onodera et al.

JOURNAL OF IMMUNOLOGY (2009)

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Article Biochemistry & Molecular Biology

Toll-like receptor 2-dependent induction of vitamin A-metabolizing enzymes in dendritic cells promotes T regulatory responses and inhibits autoimmunity

Santhakumar Manicassamy et al.

NATURE MEDICINE (2009)

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Article Multidisciplinary Sciences

Human memory FOXP3+ Tregs secrete IL-17 ex vivo and constitutively express the TH17 lineage-specific transcription factor RORγt

Maha Ayyoub et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)

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Article Multidisciplinary Sciences

Identification of IL-17-producing FOXP3+ regulatory T cells in humans

Kui Shin Voo et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)

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Article Multidisciplinary Sciences

CD4+ Regulatory T Cells Control TH17 Responses in a Stat3-Dependent Manner

Ashutosh Chaudhry et al.

SCIENCE (2009)

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Article Immunology

Retinoic Acid Enhances Foxp3 Induction Indirectly by Relieving Inhibition from CD4+CD44hi Cells

Jonathan A. Hill et al.

IMMUNITY (2008)

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Article Biochemistry & Molecular Biology

STAT6 inhibits TGF-β1-mediated Foxp3 induction through direct binding to the Foxp3 promoter, which is reverted by retinoic acid receptor

Hiromi Takaki et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2008)

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Article Immunology

In vivo equilibrium of proinflammatory IL-17+ and regulatory IL-10+ Foxp3+ RORγt+ T cells

Matthias Lochner et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2008)

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Article Immunology

Retinoic acid increases Foxp3+ regulatory T cells and inhibits development of Th17 cells by enhancing TGF-β-driven Smad3 signaling and inhibiting IL-6 and IL-23 receptor expression

Sheng Xiao et al.

JOURNAL OF IMMUNOLOGY (2008)

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Article Multidisciplinary Sciences

TGF-β-induced Foxp3 inhibits TH17 cell differentiation by antagonizing RORγt function

Liang Zhou et al.

NATURE (2008)

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Article Immunology

Regulation of humoral and cellular gut immunity by lamina propria dendritic cells expressing Toll-like receptor 5

Satoshi Uematsu et al.

NATURE IMMUNOLOGY (2008)

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Article Immunology

A dominant function for interleukin 27 in generating interleukin 10-producing anti-inflammatory T cells

Amit Awasthi et al.

NATURE IMMUNOLOGY (2007)

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Article Immunology

In vitro induction of mucosa-type dendritic cells by all-trans retinoic acid

Leslie Saurer et al.

JOURNAL OF IMMUNOLOGY (2007)

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Article Immunology

All-trans retinoic acid mediates enhanced T reg cell growth, differentiation, and gut homing in the face of high levels of co-stimulation

Micah J. Benson et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2007)

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Article Immunology

A functionally specialized population of mucosal CD103+ DCs induces Foxp3+ regulatory T cells via a TGF-β- and retinoic acid-dependent mechanism

Janine L. Coombes et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2007)

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Article Immunology

Small intestine lamina propria dendritic cells promote de novo generation of Foxp3 T reg cells via retinoic acid

Cheng-Ming Sun et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2007)

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Article Multidisciplinary Sciences

Reciprocal TH17 and regulatory T cell differentiation mediated by retinoic acid

Daniel Mucida et al.

SCIENCE (2007)

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