Related references
Note: Only part of the references are listed.Humanized mouse models for immuno-oncology research
Jane Chuprin et al.
NATURE REVIEWS CLINICAL ONCOLOGY (2023)
BTG1 mutation yields supercompetitive B cells primed for malignant transformation
Coraline Mlynarczyk et al.
SCIENCE (2023)
Combinatorial treatment rescues tumour-microenvironment-mediated attenuation of MALT1 inhibitors in B-cell lymphomas
Shivem B. Shah et al.
NATURE MATERIALS (2023)
KMT2D acetylation by CREBBP reveals a cooperative functional interaction at enhancers in normal and malignant germinal center B cells
Sofija Vlasevska et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2023)
Tracing Founder Mutations in Circulating and Tissue-Resident Follicular Lymphoma Precursors
Joseph G. Schroers-Martin et al.
CANCER DISCOVERY (2023)
HX009, a novel BsAb dual targeting PD1 x CD47, demonstrates potent anti-lymphoma activity in preclinical models
Hang Ke et al.
SCIENTIFIC REPORTS (2023)
Tumor-activated lymph node fibroblasts suppress T cell function in diffuse large B cell lymphoma
Benedetta Apollonio et al.
JOURNAL OF CLINICAL INVESTIGATION (2023)
Germinal Centers
Gabriel D. Victora et al.
ANNUAL REVIEW OF IMMUNOLOGY (2022)
The molecular ontogeny of follicular lymphoma: gene mutations succeeding the BCL2 translocation define common precursor cells
Sarah Haebe et al.
BRITISH JOURNAL OF HAEMATOLOGY (2022)
SETD2 Haploinsufficiency Enhances Germinal Center-Associated AICDA Somatic Hypermutation to Drive B- cell Lymphomagenesis
Wilfred Leung et al.
CANCER DISCOVERY (2022)
Development and Characterization of 3D Hybrid Spheroids for the Investigation of the Crosstalk Between B-Cell Non-Hodgkin Lymphomas and Mesenchymal Stromal Cells
Kamila Dus-Szachniewicz et al.
ONCOTARGETS AND THERAPY (2022)
Distinct B-Cell Specific Transcriptional Contexts of the BCL2 Oncogene Impact Pre-Malignant Development in Mouse Models
Lina Zawil et al.
CANCERS (2022)
Genome-wide Screens Identify Lineage- and Tumor-Specific Genes Modulating MHC-I- and MHC-II-Restricted Immunosurveillance of Human Lymphomas
Devin Dersh et al.
IMMUNITY (2021)
Development and Immunological Function of Lymph Node Stromal Cells
Natalia Barbara Pikor et al.
JOURNAL OF IMMUNOLOGY (2021)
Histone H1 loss drives lymphoma by disrupting 3D chromatin architecture
Nevin Yusufova et al.
NATURE (2021)
Clinical and Biological Subtypes of B-cell Lymphoma Revealed by Microenvironmental Signatures
Nikita Kotlov et al.
CANCER DISCOVERY (2021)
Developing a 3D B Cell Lymphoma Culture System to Model Antibody Therapy
Russell Foxall et al.
FRONTIERS IN IMMUNOLOGY (2021)
Advances in Human Immune System Mouse Models for Studying Human Hematopoiesis and Cancer Immunotherapy
Syed A. Mian et al.
FRONTIERS IN IMMUNOLOGY (2021)
Lymphocyte access to lymphoma is impaired by high endothelial venule regression
Lutz Menzel et al.
CELL REPORTS (2021)
Functional heterogeneity of cytotoxic T cells and tumor resistance to cytotoxic hits limit anti-tumor activity in vivo
Roxana Khazen et al.
EMBO JOURNAL (2021)
Bone Marrow Lymphoid Niche Adaptation to Mature B Cell Neoplasms
Erwan Dumontet et al.
FRONTIERS IN IMMUNOLOGY (2021)
A novel 3D culture model recapitulates primary FL B-cell features and promotes their survival
Claire Lamaison et al.
BLOOD ADVANCES (2021)
3D Model Characterization by 2D and 3D Imaging in t(14;18)-Positive B-NHL: Perspectives for In Vitro Drug Screens in Follicular Lymphoma
Fabien Gava et al.
CANCERS (2021)
A cross-talk between CAR T cell subsets and the tumor microenvironment is essential for sustained cytotoxic activity
Morgane Boulch et al.
SCIENCE IMMUNOLOGY (2021)
Follicular lymphoma triggers phenotypic and functional remodeling of the human lymphoid stromal cell landscape
Frederic Mourcin et al.
IMMUNITY (2021)
B cell/stromal cell crosstalk in health, disease, and treatment: Follicular lymphoma as a paradigm
Claire Lamaison et al.
IMMUNOLOGICAL REVIEWS (2021)
Human B Lymphomas Reveal Their Secrets Through Genetic Mouse Models
Noushin Mossadegh-Keller et al.
FRONTIERS IN IMMUNOLOGY (2021)
CREBBP/EP300 mutations promoted tumor progression in diffuse large B-cell lymphoma through altering tumor-associated macrophage polarization via FBXW7-NOTCH-CCL2/CSF1 axis
Yao-Hui Huang et al.
SIGNAL TRANSDUCTION AND TARGETED THERAPY (2021)
EZH2 inhibitors restore epigenetically silenced CD58 expression in B-cell lymphomas
Yasuyuki Otsuka et al.
MOLECULAR IMMUNOLOGY (2020)
Mutant EZH2 Induces a Pre-malignant Lymphoma Niche by Reprogramming the Immune Response
Wendy Beguelin et al.
CANCER CELL (2020)
Cathepsin S Regulates Antigen Processing and T Cell Activity in Non-Hodgkin Lymphoma
Elie Dheilly et al.
CANCER CELL (2020)
Cathepsin S Alterations Induce a Tumor-Promoting Immune Microenvironment in Follicular Lymphoma
Deepak Bararia et al.
CELL REPORTS (2020)
Mouse Models ofc-mycDeregulation Driven by IgH Locus Enhancers as Models of B-Cell Lymphomagenesis
Melissa Ferrad et al.
FRONTIERS IN IMMUNOLOGY (2020)
How the ageing microenvironment influences tumour progression
Mitchell Fane et al.
NATURE REVIEWS CANCER (2020)
Microfluidic assembly of hydrogel-based immunogenic tumor spheroids for evaluation of anticancer therapies and biomarker release
Pooja Sabhachandani et al.
JOURNAL OF CONTROLLED RELEASE (2019)
S-Geranylgeranyl-L-glutathione is a ligand for human B cell-confinement receptor P2RY8
Erick Lu et al.
NATURE (2019)
Molecular and Genetic Characterization of MHC Deficiency Identifies EZH2 as Therapeutic Target for Enhancing Immune Recognition
Daisuke Ennishi et al.
CANCER DISCOVERY (2019)
Mechanisms of Lymphoma Clearance Induced by High-Dose Alkylating Agents
Chen Lossos et al.
CANCER DISCOVERY (2019)
The HVEM-BTLA Axis Restrains T Cell Help to Germinal Center B Cells and Functions as a Cell-Extrinsic Suppressor in Lymphomagenesis
Michelle A. Mintz et al.
IMMUNITY (2019)
Unique and Shared Epigenetic Programs of the CREBBP and EP300 Acetyltransferases in Germinal Center B Cells Reveal Targetable Dependencies in Lymphoma
Stefanie N. Meyer et al.
IMMUNITY (2019)
A Tridimensional Model for NK Cell-Mediated ADCC of Follicular Lymphoma
Emilie Decaup et al.
FRONTIERS IN IMMUNOLOGY (2019)
Boosting γδ T cell-mediated antibody-dependent cellular cytotoxicity by PD-1 blockade in follicular lymphoma
Cedric Rossi et al.
ONCOIMMUNOLOGY (2019)
Oncogenic Rag GTPase signalling enhances B cell activation and drives follicular lymphoma sensitive to pharmacological inhibition of mTOR
Ana Ortega-Molina et al.
NATURE METABOLISM (2019)
Design of spherically structured 3D in vitro tumor models -Advances and prospects
L. P. Ferreira et al.
ACTA BIOMATERIALIA (2018)
Mechanisms of resistance to EZH2 inhibitors in diffuse large B-cell lymphomas
Malik Bisserier et al.
BLOOD (2018)
Microenvironment signaling driving lymphomagenesis
Lea Verdiere et al.
CURRENT OPINION IN HEMATOLOGY (2018)
Monocyte-derived IL-1 and IL-6 are differentially required for cytokine-release syndrome and neurotoxicity due to CAR T cells
Margherita Norelli et al.
NATURE MEDICINE (2018)
A human immune system mouse model with robust lymph node development
Yan Li et al.
NATURE METHODS (2018)
How Biophysical Forces Regulate Human B Cell Lymphomas
F. Apoorva et al.
CELL REPORTS (2018)
MEF2B Instructs Germinal Center Development and Acts as an Oncogene in B Cell Lymphomagenesis
Paola Brescia et al.
CANCER CELL (2018)
From genetics to the clinic: a translational perspective on follicular lymphoma
Sarah Huet et al.
NATURE REVIEWS CANCER (2018)
CTLA-4 Limits Anti-CD20-Mediated Tumor Regression
Zhenhua Ren et al.
CLINICAL CANCER RESEARCH (2017)
CREBBP Inactivation Promotes the Development of HDAC3-Dependent Lymphomas
Yanwen Jiang et al.
CANCER DISCOVERY (2017)
Award Winner in the Young Investigator Category, 2017 Society for Biomaterials Annual Meeting and Exposition, Minneapolis, MN, April 0508, 2017: Lymph node stiffness-mimicking hydrogels regulate human B-cell lymphoma growth and cell surface receptor expression in a molecular subtype-specific manner
F. N. U. Apoorva et al.
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A (2017)
Inactivation of CREBBP expands the germinal center B cell compartment, down-regulates MHCII expression and promotes DLBCL growth
Hind Hashwah et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
Genetic and epigenetic inactivation of SESTRIN1 controls mTORC1 and response to EZH2 inhibition in follicular lymphoma
Elisa Oricchio et al.
SCIENCE TRANSLATIONAL MEDICINE (2017)
EZH2 enables germinal centre formation through epigenetic silencing of CDKN1A and an Rb-E2F1 feedback loop
Wendy Beguelin et al.
NATURE COMMUNICATIONS (2017)
The CREBBP Acetyltransferase Is a Haploinsufficient Tumor Suppressor in B-cell Lymphoma
Jiyuan Zhang et al.
CANCER DISCOVERY (2017)
BCL6 Antagonizes NOTCH2 to Maintain Survival of Human Follicular Lymphoma Cells
Ester Valls et al.
CANCER DISCOVERY (2017)
B-Cell Lymphoma Patient-Derived Xenograft Models Enable Drug Discovery and Are a Platform for Personalized Therapy
Leo Zhang et al.
CLINICAL CANCER RESEARCH (2017)
Crebbp loss cooperates with Bcl2 overexpression to promote lymphoma in mice
Idoia Garcia-Ramirez et al.
BLOOD (2017)
IL-4/CXCL12 loop is a key regulator of lymphoid stroma function in follicular lymphoma
Shubham Pandey et al.
BLOOD (2017)
Recurrent mTORC1-activating RRAGC mutations in follicular lymphoma
Jessica Okosun et al.
NATURE GENETICS (2016)
B-cell-specific conditional expression of Myd88p.L252P leads to the development of diffuse large B-cell lymphoma in mice
G. Knittel et al.
BLOOD (2016)
Diffuse large B-cell lymphoma patient-derived xenograft models capture the molecular and biological heterogeneity of the disease
Bjoern Chapuy et al.
BLOOD (2016)
Loss of the HVEM Tumor Suppressor in Lymphoma and Restoration by Modified CAR-T Cells
Michael Boice et al.
CELL (2016)
An oncogenic Ezh2 mutation induces tumors through global redistribution of histone 3 lysine 27 trimethylation
George P. Souroullas et al.
NATURE MEDICINE (2016)
Integrin-specific hydrogels as adaptable tumor organoids for malignant B and T cells
Ye F. Tian et al.
BIOMATERIALS (2015)
Ex vivo engineered immune organoids for controlled germinal center reactions
Alberto Purwada et al.
BIOMATERIALS (2015)
Lectin binding to surface Ig variable regions provides a universal persistent activating signal for follicular lymphoma cells
Adam Linley et al.
BLOOD (2015)
DC-SIGN-expressing macrophages trigger activation of mannosylated IgM B-cell receptor in follicular lymphoma
Rada Amin et al.
BLOOD (2015)
Disruption of KMT2D perturbs germinal center B cell development and promotes lymphomagenesis
Jiyuan Zhang et al.
NATURE MEDICINE (2015)
The histone lysine methyltransferase KMT2D sustains a gene expression program that represses B cell lymphoma development
Ana Ortega-Molina et al.
NATURE MEDICINE (2015)
Mutations in early follicular lymphoma progenitors are associated with suppressed antigen presentation
Michael R. Green et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Discovery of a drug targeting microenvironmental support for lymphoma cells by screening using patient-derived xenograft cells
Keiki Sugimoto et al.
SCIENTIFIC REPORTS (2015)
Light-triggered in vivo activation of adhesive peptides regulates cell adhesion, inflammation and vascularization of biomaterials
Ted T. Lee et al.
NATURE MATERIALS (2015)
Lymph node fibroblastic reticular cells in health and disease
Anne L. Fletcher et al.
NATURE REVIEWS IMMUNOLOGY (2015)
Germinal centres and B cell lymphomagenesis
Katia Basso et al.
NATURE REVIEWS IMMUNOLOGY (2015)
Cell Growth in Aggregates Determines Gene Expression, Proliferation, Survival, Chemoresistance, and Sensitivity to Immune Effectors in Follicular Lymphoma
Pauline Gravelle et al.
AMERICAN JOURNAL OF PATHOLOGY (2014)
Germinal center reentries of BCL2-overexpressing B cells drive follicular lymphoma progression
Stephanie Sungalee et al.
JOURNAL OF CLINICAL INVESTIGATION (2014)
t(14;18) Translocation: A Predictive Blood Biomarker for Follicular Lymphoma
Sandrine Roulland et al.
JOURNAL OF CLINICAL ONCOLOGY (2014)
Frequent disruption of the RB pathway in indolent follicular lymphoma suggests a new combination therapy
Elisa Oricchio et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2014)
Loss of signalling via Gα13 in germinal centre B-cell-derived lymphoma
Jagan R. Muppidi et al.
NATURE (2014)
The tumour microenvironment in B cell lymphomas
David W. Scott et al.
NATURE REVIEWS CANCER (2014)
EZH2 Is Required for Germinal Center Formation and Somatic EZH2 Mutations Promote Lymphoid Transformation
Wendy Beguelin et al.
CANCER CELL (2013)
Germinal center dysregulation by histone methyltransferase EZH2 promotes lymphomagenesis
Marieta Caganova et al.
JOURNAL OF CLINICAL INVESTIGATION (2013)
ABT-199, a potent and selective BCL-2 inhibitor, achieves antitumor activity while sparing platelets
Andrew J. Souers et al.
NATURE MEDICINE (2013)
Anti-tumor activity of obinutuzumab and rituximab in a follicular lymphoma 3D model
E. Decaup et al.
BLOOD CANCER JOURNAL (2013)
Mesenchymal stromal cells orchestrate follicular lymphoma cell niche through the CCL2-dependent recruitment and polarization of monocytes
Fabien Guilloton et al.
BLOOD (2012)
Characterization of intratumoral follicular helper T cells in follicular lymphoma: role in the survival of malignant B cells
P. Ame-Thomas et al.
LEUKEMIA (2012)
EZH2 inhibition as a therapeutic strategy for lymphoma with EZH2-activating mutations
Michael T. McCabe et al.
NATURE (2012)
Stromal cell contribution to human follicular lymphoma pathogenesis
Frederic Mourcin et al.
FRONTIERS IN IMMUNOLOGY (2012)
Cooperative function of CCR7 and lymphotoxin in the formation of a lymphoma-permissive niche within murine secondary lymphoid organs
Armin Rehm et al.
BLOOD (2011)
The Eph-Receptor A7 Is a Soluble Tumor Suppressor for Follicular Lymphoma
Elisa Oricchio et al.
CELL (2011)
The immunoglobulin heavy chain gene 3′ enhancers induce Bcl2 deregulation and lymphomagenesis in murine B cells
H. Xiang et al.
LEUKEMIA (2011)
The sphingosine 1-phosphate receptor S1P2 maintains the homeostasis of germinal center B cells and promotes niche confinement
Jesse A. Green et al.
NATURE IMMUNOLOGY (2011)
Follicular dendritic cell-dependent drug resistance of non-Hodgkin lymphoma involves cell adhesion-mediated Bim down-regulation through induction of microRNA-181a
Tint Lwin et al.
BLOOD (2010)
Follicular lymphoma cell niche: identification of a preeminent IL-4-dependent TFH-B cell axis
C. Pangault et al.
LEUKEMIA (2010)
T-cell modulation combined with intratumoral CpG cures lymphoma in a mouse model without the need for chemotherapy
Roch Houot et al.
BLOOD (2009)
Tumor burden influences exposure and response to rituximab: pharmacokinetic-pharmacodynamic modeling using a syngeneic bioluminescent murine model expressing human CD20
David Dayde et al.
BLOOD (2009)
Therapeutic effect of CD137 immunomodulation in lymphoma and its enhancement by Treg depletion
Roch Houot et al.
BLOOD (2009)
Targeted Disruption of the S1P2 Sphingosine 1-Phosphate Receptor Gene Leads to Diffuse Large B-Cell Lymphoma Formation
Giorgio Cattoretti et al.
CANCER RESEARCH (2009)
Lymphoma cell adhesion-induced expression of B cell-activating factor of the TNF family in bone marrow stromal cells protects non-Hodgkin's B lymphoma cells from apoptosis
T. Lwin et al.
LEUKEMIA (2009)
Stromal Gene Signatures in Large-B-Cell Lymphomas
G. Lenz et al.
NEW ENGLAND JOURNAL OF MEDICINE (2008)
Polymorphism in Sirpa modulates engraftment of human hematopoietic stem cells
Katsuto Takenaka et al.
NATURE IMMUNOLOGY (2007)
Human mesenchymal stem cells isolated from bone marrow and lymphoid organs support tumor B-cell growth:: role of stromal cells in follicular lymphoma pathogenesis
Patricia Ame-Thomas et al.
BLOOD (2007)
VavP-Bcl2 transgenic mice develop follicular lymphoma preceded by germinal center hyperplasia
A Egle et al.
BLOOD (2004)