New insight into molecular mechanisms underlying division of labor in honeybees

Honeybees are highly organized eusocial insects displaying a distinct division of labor. Juvenile hormone (JH) has long been hypothesized to be the major driver of behavioral transitions. However, more and more experiments in recent years have suggested that the role of this hormone is not as fundamental as hypothesized. Vitellogenin, a common egg yolk precursor protein, seems to be the major regulator of division of labor in honeybees, in connection with nutrition and the neurohormone and transmitter octopamine. Here, we review the role of vitellogenin in controlling honeybee division of labor and its modulation by JH, nutrition, and the catecholamine octopamine.

Automated summary

Honeybees have a clear division of labor and vitellogenin protein, along with nutrition and octopamine, plays a major role in regulating this division. However, the importance of juvenile hormone in this process is not as significant as previously thought.