Synthesis, Characterization and Structural Analysis of Two New Biguanide Complexes

This study reports on the synthesis and characterization of two new coordination compounds of the active pharmaceutical ingredient metformin and transition metals. The cobalt compound with the formula [Co(Met)(3)][CoCl4]Cl center dot 3H(2)O is a complex salt formed by a cationic Co(III) octahedral and anionic Co(II) tetrahedral subunits. The Cu(II) complex is represented by the formula [(Cu(Met)Cl)(2)-mu-Cl-2] and is a dimeric compound with two chloride anions acting as a bridge, forming shared-edge square pyramidal units. Both compounds were characterized by single crystal X-ray diffraction, FT-IR spectroscopy and thermal analysis.

Automated summary

This study presents the synthesis and characterization of two new coordination compounds of metformin and transition metals. The cobalt compound [Co(Met)(3)][CoCl4]Cl·3H2O consists of a cationic Co(III) octahedral unit and anionic Co(II) tetrahedral subunits. The copper compound [(Cu(Met)Cl)(2)-μ-Cl-2] is a dimeric complex with bridging chloride anions, forming shared-edge square pyramidal units.