4.6 Article

Optimization of Indirect CAP Exposure as an Effective Osteosarcoma Cells Treatment with Cytotoxic Effects

Related references

Note: Only part of the references are listed.
Article Cell Biology

Chloroquine Enhances Death in Lung Adenocarcinoma A549 Cells Exposed to Cold Atmospheric Plasma Jet

Ekaterina Patrakova et al.

Summary: Cold atmospheric plasma (CAP) is a widely studied approach for treating malignant neoplasms. This study determined the optimal discharge regime for direct CAP treatment of cancer cells and found that CAP weakly activated pro-survival autophagy in irradiated cells. The addition of the autophagy inhibitor chloroquine (CQ) promoted CAP-dependent cell death.

CELLS (2023)

Review Biochemistry & Molecular Biology

Exploring the Use of Cold Atmospheric Plasma to Overcome Drug Resistance in Cancer

Dzohara Murillo et al.

Summary: Drug resistance is a major problem in cancer treatment, and cold atmospheric plasma (CAP) shows promise in overcoming it. CAP uses ionized gas to generate reactive species that can kill cancer cells. This review explores the mechanisms behind CAP's effectiveness and its potential applications in cancer treatment. Further research is needed to address the challenges and opportunities in this field.

BIOMEDICINES (2023)

Article Food Science & Technology

Production, characterization, microbial inhibition, and in vivo toxicity of cold atmospheric plasma activated water

George Katsaros et al.

Summary: Cold atmospheric plasma activated water (PAW) was produced at different concentrations of Reactive Nitrogen Oxygen Species (RONS). PAW was characterized and its in vivo toxicological effects were studied using zebrafish embryo acute toxicity test. The results showed that a H2O2 concentration of approximately 30 mg/L and the pH value of 3.85 were the thresholds for no lethality and no obvious morphological phenotypes in the embryos. PAW had inhibitory potential for Escherichia coli and Enterococcus faecium, delaying their recovery time or even preventing their growth.

INNOVATIVE FOOD SCIENCE & EMERGING TECHNOLOGIES (2023)

Article Endocrinology & Metabolism

Enhanced growth factor expression in chronic diabetic wounds treated by cold atmospheric plasma

Jonas Hiller et al.

Summary: This study aimed to investigate the molecular drivers responsible for the observed improvement in diabetic wound healing by cold atmospheric plasma (CAP).

DIABETIC MEDICINE (2022)

Review Biochemistry & Molecular Biology

Cold atmospheric plasma therapy in wound healing

Sunil Kumar Dubey et al.

Summary: Cold atmospheric plasma therapy is a novel, simple, non-invasive treatment approach mainly used in wound healing. It is distinct from blood plasma and is generated as the fourth state of matter through irradiation or electric field. This review emphasizes the application of cold plasma in wound healing, discussing wound types, healing process, and mechanisms of cold atmospheric plasma therapy.

PROCESS BIOCHEMISTRY (2022)

Article Chemistry, Multidisciplinary

Cold Atmospheric Plasma, Platelet-Rich Plasma, and Nitric Oxide Synthesis Inhibitor: Effects Investigation on an Experimental Model on Rats

Bogdan Caba et al.

Summary: This study investigated the effects of cold atmospheric plasma (CAP), L-NAME, and PRP injectable solutions on flap survival. The results showed that the necrosis area of the flaps was significantly lower in the CAP, L-NAME, and PRP groups compared to the control group. Thermography exploration also revealed less ischemia in the treated groups. Additionally, anatomopathological data indicated that the CAP group had the best degree of angiogenesis. Overall, the CAP activated solution had a similar (or even better) impact on flap necrosis rate and offered fast, unlimited, non-invasive, and standardized treatment.

APPLIED SCIENCES-BASEL (2022)

Article Oncology

Cold Atmospheric Plasma Attenuates Breast Cancer Cell Growth Through Regulation of Cell Microenvironment Effectors

Christos A. Aggelopoulos et al.

Summary: This study investigated the effects of cold atmospheric plasma (CAP) treatment on breast cancer cells of different phenotypes and estrogen receptor (ER) status. CAP treatment induced phenotypic changes and apoptosis in breast cancer cells, and significantly reduced CD44 protein expression. CAP could be an efficient therapeutic approach for distinct breast cancer subtypes.

FRONTIERS IN ONCOLOGY (2022)

Article Materials Science, Multidisciplinary

Cold atmospheric plasma delivery for biomedical applications

Zhitong Chen et al.

Summary: This article introduces the delivery methods of cold atmospheric plasma (CAP) in biomedical applications, such as sterilization, wound healing, and cancer therapy. It also presents the future research needs in this field, providing insights for researchers from various disciplines.

MATERIALS TODAY (2022)

Review Medicine, General & Internal

Therapeutic Effects of Cold Atmospheric Plasma on Solid Tumor

Tianhao Min et al.

Summary: This article presents a narrative review on the therapeutic effects and killing mechanism of cold atmospheric plasma (CAP) on solid tumors. The effects of CAP on tumor cells, tumor microenvironment, and the immune system are discussed, along with proposed therapeutic schemes and research directions.

FRONTIERS IN MEDICINE (2022)

Article Physics, Applied

Investigation of different solutions activated by air plasma jet and their anticancer effect

Jin Zhang et al.

Summary: In the field of plasma biomedicine, research on plasma-activated medium (PAM) has gained attention for its excellent characteristics. By using an atmospheric pressure air plasma jet to treat different solutions, this study analyzed the property differences of PAM and evaluated its inactivation effects on lung cancer cells. The results showed that the concentration of reactive species in PAM increased with treatment time. Furthermore, plasma-activated PBS demonstrated the best antitumor effect and promoted apoptosis in A549 cells.

APPLIED PHYSICS LETTERS (2022)

Article Medicine, General & Internal

Osteosarcoma A

Hannah C. Beird et al.

Summary: Osteosarcoma is the most common primary malignant bone tumor with a bimodal incidence peaking at 18 and 60 years of age. It is more common in males and is driven by genetic factors related to bone formation leading to malignant progression and metastasis. Screening is currently focused on high-risk groups, and the prognosis for patients with metastatic disease remains poor.

NATURE REVIEWS DISEASE PRIMERS (2022)

Review Nutrition & Dietetics

Food preservation by cold plasma from dielectric barrier discharges in agri-food industries

Hao Jiang et al.

Summary: Cold plasma technology has the potential to replace traditional agri-food processing purification methods due to its ability to meet microbial food safety standards and improve product quality characteristics. However, a comprehensive assessment is needed considering economic, ecological, and consumer benefits and acceptability.

FRONTIERS IN NUTRITION (2022)

Article Nanoscience & Nanotechnology

Properties and anticancer effects of plasma-activated medium stored at different temperatures

Runze Fan et al.

Summary: Plasma-activated solution (PAS) is receiving significant attention in cancer treatment due to its ability to treat deep tumors and be stored. This study investigated the changes in PAS during storage and its impact on its anticancer effect. The plasma-activated medium (PAM) was prepared by treating RPMI 1640 medium with afterglow gas, and it was stored at different temperatures for varying durations. The results showed that PAM exhibited different anticancer effects depending on the storage temperature, with the highest stability observed at -80 degrees C. These findings provide valuable insights into the storage and application of PAM in anticancer therapy.

AIP ADVANCES (2022)

Review Oncology

Plasma oncology: Adjuvant therapy for head and neck cancer using cold atmospheric plasma

Xuran Li et al.

Summary: This article provides a comprehensive review of the oncological potential of cold atmospheric plasma (CAP) in the treatment of head and neck cancer (HNC). It discusses the anti-tumor effect of CAP in various types of HNC, including upper aerodigestive tract cancers, head and neck glandular cancers, and skin cancers. CAP is a versatile treatment option that can be used for different types of tumors and can work in synergy with existing clinical therapies.

FRONTIERS IN ONCOLOGY (2022)

Review Physics, Fluids & Plasmas

Improving Seed Germination by Cold Atmospheric Plasma

Dayun Yan et al.

Summary: Cold atmospheric plasma (CAP) is a tunable source of reactive species that exerts biochemical effects on diverse cells. It shows promising application in modern agriculture, particularly in improving seed germination rates. This article discusses the state of the art in plasma agriculture, including typical plasma sources and the chemical and cellular mechanisms behind plasma's effect on plant seeds.

PLASMA (2022)

Review Instruments & Instrumentation

Applications of cold atmospheric plasma for transdermal drug delivery: a review

Xiang Wen et al.

Summary: Transdermal drug delivery is difficult due to the obstruction of the stratum corneum, but cold atmospheric plasma (CAP) pretreatment can enhance drug delivery into the skin and systemic circulation. CAP can improve drug penetration by changing skin properties through various effects. While more research is needed, CAP shows promise as a non-invasive and efficient pretreatment for improving drug permeation in clinical practice.

DRUG DELIVERY AND TRANSLATIONAL RESEARCH (2021)

Article Food Science & Technology

The impact of food model system structure on the inactivation of Listeria innocua by cold atmospheric plasma and nisin combined treatments

Katherine M. Costello et al.

Summary: Novel processing methods like CAP and natural antimicrobials such as nisin are being explored to replace traditional food decontamination approaches, as they can maintain desirable food characteristics while being mild. However, microbial growth characteristics and food structure can impact the efficacy of these methods. The combination of nisin and CAP was found to be more effective than individual treatments, but only when nisin was applied before the CAP treatment.

INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY (2021)

Review Biochemistry & Molecular Biology

Effect of Cold Atmospheric Plasma on Epigenetic Changes, DNA Damage, and Possibilities for Its Use in Synergistic Cancer Therapy

Dusan Brany et al.

Summary: Cold atmospheric plasma shows great potential in modern medicine. It has been used in clinical treatment of skin diseases, chronic wounds, and has effects on tumour cells. Current research focuses on its applications in internal structures and its synergistic effects with pharmaceuticals.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

Review Engineering, Biomedical

Osteosarcoma: a review of current and future therapeutic approaches

Xin Zhao et al.

Summary: Osteosarcoma is a common primary bone malignancy that poses a serious threat to human health globally, characterized by high malignancy and rapid progression. The incidence of osteosarcoma has a bimodal distribution pattern with peaks in different age groups, mainly presenting as single lesions. This article summarizes the types, clinical diagnosis, and treatment methods of osteosarcoma.

BIOMEDICAL ENGINEERING ONLINE (2021)

Article Food Science & Technology

The antimicrobial efficacy of remote cold atmospheric plasma effluent against single and mixed bacterial biofilms of varying age

Hani El Kadri et al.

Summary: Cold atmospheric plasma (CAP) is a mild food processing technology that can maintain food quality, but its impact on biofilms and mechanisms of action are not well studied, with limited research on real food applications.

FOOD RESEARCH INTERNATIONAL (2021)

Article Biochemistry & Molecular Biology

Osteosarcoma tissue-engineered model challenges oxidative stress therapy revealing promoted cancer stem cell properties

Juan Tornin et al.

Summary: The use of Cold Atmospheric Plasma (CAP) for anti-cancer therapy is being studied, with benefits demonstrated in 2D cell cultures but needing validation in 3D environments. A 3D tissue-engineered model using a bone-like scaffold has shown potential for evaluating CAP effects on osteosarcoma more accurately.

FREE RADICAL BIOLOGY AND MEDICINE (2021)

Review Chemistry, Multidisciplinary

Applications of Cold Atmospheric Pressure Plasma in Dentistry

Aline C. Borges et al.

Summary: Plasma is an electrically conducting medium that responds to electric and magnetic fields. Non-thermal plasmas contain highly reactive species at low temperatures, showing promising applications in the medical field.

APPLIED SCIENCES-BASEL (2021)

Review Medicine, General & Internal

Cold Atmospheric Plasma: A New Strategy Based Primarily on Oxidative Stress for Osteosarcoma Therapy

Miguel Mateu-Sanz et al.

Summary: This review discusses the current status of cold plasma therapy for osteosarcoma, emphasizing the mechanisms of action of plasmas on this type of bone tumor. The main challenge for the future development of osteosarcoma therapies based on cold plasma lies in overcoming critical barriers to progress in this emerging technique.

JOURNAL OF CLINICAL MEDICINE (2021)

Review Infectious Diseases

The Antimicrobial Effect of Cold Atmospheric Plasma against Dental Pathogens-A Systematic Review of In-Vitro Studies

Gert Jungbauer et al.

Summary: This article reviewed 55 in-vitro studies on the antimicrobial effect of cold atmospheric plasma (CAP) on dental pathogens. The results showed a time-dependent increase of the antimicrobial effect of CAP. Although there were differences in the results among studies, clusters could be identified based on the pathogen, working gases, and treatment time intervals. CAP may be a promising alternative for antimicrobial treatment in dentistry, but further research is needed for verification.

ANTIBIOTICS-BASEL (2021)

Article Materials Science, Multidisciplinary

Simulation of Cold Atmospheric Plasma Generated by Floating-Electrode Dielectric Barrier Pulsed Discharge Used for the Cancer Cell Necrosis

Samira Elaissi et al.

Summary: The numerical simulation of FE-DBD for melanoma cancer cell therapy shows the importance of optimizing plasma device characteristics, inter-electrode distance, and power supply for efficiency improvement. The sensitivity of FE-DBD to short pulse durations and the increase in energy injection with higher applied voltage are key factors in enhancing treatment efficacy.

COATINGS (2021)

Review Biochemistry & Molecular Biology

Applications of Plasma-Activated Liquid in the Medical Field

Sungryeal Kim et al.

Summary: Plasma has developed from thermal to nonthermal type, with cold plasma being extensively researched. The interaction of plasma and liquid resulted in PAL, now widely used in various fields.

BIOMEDICINES (2021)

Article Chemistry, Multidisciplinary

Open-Air Cold Plasma Device Leads to Selective Tumor Cell Cytotoxicity

Catarina Almeida-Ferreira et al.

Summary: This study revealed that cold atmospheric plasma exhibits higher cytotoxicity in various cancer cells, possibly related to increased production of hydrogen peroxide. Sixty seconds of CAP exposure has selective effects, preserving the viability of fibroblast cells. These findings highlight the importance of further research on plasma therapy.

APPLIED SCIENCES-BASEL (2021)

Article Biochemistry & Molecular Biology

Cold Atmospheric Plasma Changes the Amino Acid Composition of Solutions and Influences the Anti-Tumor Effect on Melanoma Cells

Stephanie Arndt et al.

Summary: Cold Atmospheric Plasma (CAP) has anti-tumor effects transmitted through direct treatment or plasma-treated solutions (PTS) containing various amino acids and vitamins. Different plasma modes and treatment durations affect the production of reactive species in PTS, influencing the composition of active components and anti-tumor mechanisms. The findings are crucial for plasma device development and tumor treatment effectiveness.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

Article Multidisciplinary Sciences

Selectivity of direct plasma treatment and plasma-conditioned media in bone cancer cell lines

Ines Hamouda et al.

Summary: Atmospheric pressure plasma jets have shown potential impact in bone cancer therapy by inducing cancer cell death through the generation of reactive species. Variability in sensitivity to reactive species exists among different cells, but plasma treatment still exhibits selectivity towards bone cancer cells, with minimal effect on non-malignant cell survival.

SCIENTIFIC REPORTS (2021)

Review Chemistry, Multidisciplinary

Applications of Cold Atmospheric Pressure Plasma Technology in Medicine, Agriculture and Food Industry

Maria Domonkos et al.

Summary: In recent years, cold atmospheric pressure plasma (CAPP) technology has garnered attention for its simplicity, cost-effectiveness, and environmental friendliness. It can be used to modify material surfaces and inactivate pathogens, with promising applications in medicine.

APPLIED SCIENCES-BASEL (2021)

Article Physics, Applied

Influence of liquid coverage on the anticancer effects of a helium plasma jet on 3D tumor spheroids

Jishen Zhang et al.

PLASMA PROCESSES AND POLYMERS (2020)

Article Oncology

Cold Plasma-Treated Ringer's Saline: A Weapon to Target Osteosarcoma

Miguel Mateu-Sanz et al.

CANCERS (2020)

Review Biochemistry & Molecular Biology

Cold Atmospheric Plasma: A Powerful Tool for Modern Medicine

Dusan Brany et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)

Article Physics, Applied

Plasma-activated water from a dielectric barrier discharge plasma source for the selective treatment of cancer cells

P. S. Ganesh Subramanian et al.

PLASMA PROCESSES AND POLYMERS (2020)

Review Chemistry, Multidisciplinary

The Emerging Role of Cold Atmospheric Plasma in Implantology: A Review of the Literature

Wang Lai Hui et al.

NANOMATERIALS (2020)

Article Physics, Fluids & Plasmas

Perspectives on cold atmospheric plasma (CAP) applications in medicine

Thomas von Woedtke et al.

PHYSICS OF PLASMAS (2020)

Article Multidisciplinary Sciences

Cold atmospheric plasma as an effective method to treat diabetic foot ulcers: A randomized clinical trial

Shahriar Mirpour et al.

SCIENTIFIC REPORTS (2020)

Review Engineering, Chemical

Important parameters in plasma jets for the production of RONS in liquids for plasma medicine: A brief review

Anna Khlyustova et al.

FRONTIERS OF CHEMICAL SCIENCE AND ENGINEERING (2019)

Article Multidisciplinary Sciences

Pyruvate Plays a Main Role in the Antitumoral Selectivity of Cold Atmospheric Plasma in Osteosarcoma

Juan Tornin et al.

SCIENTIFIC REPORTS (2019)

Article Cell & Tissue Engineering

Wound Healing Potential of Low Temperature Plasma in Human Primary Epidermal Keratinocytes

Hui Song Cui et al.

TISSUE ENGINEERING AND REGENERATIVE MEDICINE (2019)

Article Instruments & Instrumentation

Deducing rotational quantum-state distributions from overlapping molecular spectra

Jan Vorac et al.

REVIEW OF SCIENTIFIC INSTRUMENTS (2019)

Article Multidisciplinary Sciences

Production of reactive species in alginate hydrogels for cold atmospheric plasma-based therapies

Cedric Labay et al.

SCIENTIFIC REPORTS (2019)

Editorial Material Biotechnology & Applied Microbiology

Plasma in Dentistry: Brief History and Current Status

Matteo Gherardi et al.

TRENDS IN BIOTECHNOLOGY (2018)

Review Oncology

Use of cold-atmospheric plasma in oncology: a concise systematic review

Antoine Dubuc et al.

THERAPEUTIC ADVANCES IN MEDICAL ONCOLOGY (2018)

Article Biochemistry & Molecular Biology

Plasma-induced selectivity in bone cancer cells death

Cristina Canal et al.

FREE RADICAL BIOLOGY AND MEDICINE (2017)

Review Biochemistry & Molecular Biology

Cold Atmospheric Plasma in the Treatment of Osteosarcoma

Denis Guembel et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2017)

Editorial Material Respiratory System

Cancer prevention from the perspective of global cancer burden patterns

Hiroki Nagai et al.

JOURNAL OF THORACIC DISEASE (2017)

Article Multidisciplinary Sciences

The Specific Vulnerabilities of Cancer Cells to the Cold Atmospheric Plasma-Stimulated Solutions

Dayun Yan et al.

SCIENTIFIC REPORTS (2017)

Review Physics, Fluids & Plasmas

Dielectric barrier discharges: progress on plasma sources and on the understanding of regimes and single filaments

Ronny Brandenburg

PLASMA SOURCES SCIENCE & TECHNOLOGY (2017)

Article Biochemistry & Molecular Biology

The effects of cold atmospheric plasma on cell adhesion, differentiation, migration, apoptosis and drug sensitivity of multiple myeloma

Dehui Xu et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2016)

Article Multidisciplinary Sciences

Synergistic Effect of H2O2 and NO2 in Cell Death Induced by Cold Atmospheric He Plasma

Pierre-Marie Girard et al.

SCIENTIFIC REPORTS (2016)

Article Multidisciplinary Sciences

Non-thermal atmospheric pressure plasma activates lactate in Ringer's solution for anti-tumor effects

Hiromasa Tanaka et al.

SCIENTIFIC REPORTS (2016)

Article Pharmacology & Pharmacy

Plasma treatment for improving cell biocompatibility of a biodegradable polymer scaffold for vascular graft applications

Sarra de Valence et al.

EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS (2013)

Review Engineering, Biomedical

Cold atmospheric plasma devices for medical issues

Georg Isbary et al.

EXPERT REVIEW OF MEDICAL DEVICES (2013)

Article Multidisciplinary Sciences

Restoration of Sensitivity in Chemo - Resistant Glioma Cells by Cold Atmospheric Plasma

Julia Koeritzer et al.

PLOS ONE (2013)

Review Medicine, Research & Experimental

Cold Atmospheric Plasma: methods of production and application in dentistry and oncology

Clotilde Hoffmann et al.

MEDICAL GAS RESEARCH (2013)

Review Physics, Applied

Low temperature atmospheric pressure plasma sources for microbial decontamination

J. Ehlbeck et al.

JOURNAL OF PHYSICS D-APPLIED PHYSICS (2011)

Article Materials Science, Multidisciplinary

Cold atmospheric plasma: Sources, processes, and applications

L. Bardos et al.

THIN SOLID FILMS (2010)

Review Physics, Applied

Arc-free atmospheric pressure cold plasma jets: A review

Mounir Laroussi et al.

PLASMA PROCESSES AND POLYMERS (2007)

Article Biochemistry & Molecular Biology

A rapid, simple spectrophotometric method for simultaneous detection of nitrate and nitrite

KM Miranda et al.

NITRIC OXIDE-BIOLOGY AND CHEMISTRY (2001)