Islet autoimmunity and type 1 diabetes associated with enterovirus infections

Editorial Material Endocrinology & Metabolism

Sleep and cardiometabolic health-not so strange bedfellows

Shahrad Taheri

LANCET DIABETES & ENDOCRINOLOGY (2023)

Article Endocrinology & Metabolism

Live enteroviruses, but not other viruses, detected in human pancreas at the onset of type 1 diabetes in the DiViD study

Lars Krogvold et al.

Summary: This study has found the presence of enterovirus genomes in the pancreas of type 1 diabetes patients, suggesting a potential link between enterovirus infection and the development of type 1 diabetes.

DIABETOLOGIA (2022)

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Review Endocrinology & Metabolism

Type 1 diabetes in diverse ancestries and the use of genetic risk scores

Maria J. Redondo et al.

Summary: This review provides an overview of the development and application of genetic risk scores (GRS) in type 1 diabetes, highlighting the differences in type 1 diabetes genetics among populations of diverse genetic ancestries.

LANCET DIABETES & ENDOCRINOLOGY (2022)

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Article Endocrinology & Metabolism

Coxsackievirus B Vaccines Prevent Infection-Accelerated Diabetes in NOD Mice and Have No Disease-Inducing Effect

Virginia M. Stone et al.

Summary: This study demonstrates that CVB vaccines do not alter islet inflammation or accelerate disease progression in an animal model that spontaneously develops autoimmune type 1 diabetes. However, they can prevent CVB-mediated disease progression in the same model.

DIABETES (2021)

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Review Multidisciplinary Sciences

Preventing type 1 diabetes in childhood

Colin M. Dayan et al.

Summary: Recent studies have shown that monitoring pancreatic islet autoantibodies and genetic risk assessment can identify most children who will develop T1D, with immunotherapy and primary prevention methods showing success in delaying disease progression. By shifting focus towards early diagnosis and b cell preservation, a future without daily insulin injections for children with T1D is anticipated.

SCIENCE (2021)

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Review Cell Biology