Associations between COVID-19 outcomes and asthmatic patients with inhaled corticosteroid

Article Rheumatology

COVID-19 outcomes among rheumatic disease patients in Kuwait: Data from the COVID-19 Global Rheumatology Alliance (C19-GRA) physician registry

Fatemah Abutiban et al.

Summary: This study collected and analyzed COVID-19-related data of IRD patients in Kuwait, providing insights into patient characteristics and factors associated with hospitalization, complications, and mortality.

INTERNATIONAL JOURNAL OF RHEUMATIC DISEASES (2022)

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Article Respiratory System

Relationship between asthma and severe COVID-19: a national cohort study

Ted Dolby et al.

Summary: The study aimed to determine whether individuals with poorly controlled or severe asthma have a higher risk of hospitalization and/or death from COVID-19. The results suggest that individuals with mild and well-controlled asthma do not have a significantly increased risk of hospitalization or death from COVID-19 compared to individuals without asthma.

THORAX (2022)

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Article Medicine, General & Internal

Analysis of Neuropsychiatric Diagnoses After Montelukast Initiation

Tapio Paljarvi et al.

Summary: This study found that patients with asthma or allergic rhinitis had increased odds of adverse neuropsychiatric outcomes after montelukast initiation.

JAMA NETWORK OPEN (2022)

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Article Psychiatry

Neurological and psychiatric risk trajectories after SARS-CoV-2 infection: an analysis of 2-year retrospective cohort studies including 1 284 437 patients

Maxime Taquet et al.

Summary: COVID-19 is associated with increased risks of neurological and psychiatric sequelae. The duration of these risks, their impact on children and adults, and the differences in risk profiles among SARS-CoV-2 variants remain unclear. A 2-year retrospective cohort study analyzed data from electronic health records of COVID-19 patients and found that the risk trajectories differed based on age and outcome. While the risk of mood and anxiety disorders returned to baseline after 1-2 months, the risks of cognitive deficit, dementia, psychotic disorders, and epilepsy or seizures remained increased at the end of the 2-year follow-up period. Children had a more benign overall profile of psychiatric risk but sustained higher risk for certain diagnoses. The findings highlight the importance of understanding the individual and population-level risks of neurological and psychiatric disorders after SARS-CoV-2 infection.

LANCET PSYCHIATRY (2022)

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Letter Respiratory System

Inhaled corticosteroids and COVID-19 outcomes in asthma: the Israeli experience

Yochai Adir et al.

ERJ OPEN RESEARCH (2022)

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Editorial Material Respiratory System

Asthma and COVID-19: do we finally have answers?

Katrien Eger et al.

EUROPEAN RESPIRATORY JOURNAL (2021)

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Article Critical Care Medicine

Risk of adverse outcomes in patients with underlying respiratory conditions admitted to hospital with COVID-19 a national, multicentre prospective cohort study using the ISARIC WHO Clinical Characterisation Protocol UK

Chloe Bloom et al.

Summary: This study analyzed data from patients admitted to hospital with COVID-19 in England, Scotland, and Wales from January 17 to August 3, 2020. The findings showed that patients with asthma were more likely to receive critical care, while patients with chronic pulmonary disease were less likely. In older patients, inhaled corticosteroid use reduced mortality rates in asthma patients but not in those with chronic pulmonary disease.

LANCET RESPIRATORY MEDICINE (2021)

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Article Allergy

COVID-19 Susceptibility in Bronchial Asthma

Ilan Green et al.

Summary: The study on the prevalence and related factors of asthma in COVID-19 patients shows that patients with asthma have a lower susceptibility to COVID-19, and there is no significant correlation between asthma patients and the positivity rate of COVID-19.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE (2021)

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Article Critical Care Medicine

Association between pre-existing respiratory disease and its treatment, and severe COVID-19: a population cohort study

Paul Aveyard et al.

Summary: The study found that patients with certain respiratory diseases had a higher risk of hospitalization and death from COVID-19, while the risk of severe COVID-19 in asthma patients was relatively small. The use of inhaled steroids may be associated with a slightly increased risk of severe COVID-19.

LANCET RESPIRATORY MEDICINE (2021)

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Article Medicine, General & Internal

Prevention and Attenuation of Covid-19 with the BNT162b2 and mRNA-1273 Vaccines

Mark G. Thompson et al.

Summary: The study demonstrated that COVID-19 mRNA vaccines were highly effective in preventing SARS-CoV-2 infection in real-world conditions, while also attenuating the viral RNA load, febrile symptoms, and illness duration among vaccinated individuals who had breakthrough infections.

NEW ENGLAND JOURNAL OF MEDICINE (2021)

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Article Respiratory System

The impact of COVID-19 on patients with asthma

Jose Luis Izquierdo et al.

Summary: The study analyzed clinical data of 71,182 asthma patients and found that those with COVID-19 were older, predominantly female, and had higher prevalence of comorbidities. The use of inhaled corticosteroids and biologics in asthma patients may have a protective effect against severe COVID-19 infection.

EUROPEAN RESPIRATORY JOURNAL (2021)

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Article Respiratory System

Effect of asthma and asthma medication on the prognosis of patients with COVID-19

Yong Jun Choi et al.

Summary: The study found that asthma patients with COVID-19 had a significantly higher mortality rate than other patients, but asthma was not an independent risk factor for the clinical outcomes of COVID-19. Furthermore, asthma medication use and asthma severity did not affect the clinical outcomes of COVID-19.

EUROPEAN RESPIRATORY JOURNAL (2021)

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Article Critical Care Medicine