Related references
Note: Only part of the references are listed.Dexmedetomidine Restores Autophagic Flux, Modulates Associated microRNAs and the Cholinergic Anti-inflammatory Pathway upon LPS-Treatment in Rats
Widuri Kho et al.
JOURNAL OF NEUROIMMUNE PHARMACOLOGY (2022)
Intraoperative dexmedetomidine for prevention of postoperative delirium in elderly patients with mild cognitive impairment
Xi Xin et al.
INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY (2021)
Modulatory Effects of Autophagy on APP Processing as a Potential Treatment Target for Alzheimer's Disease
Md. Ataur Rahman et al.
BIOMEDICINES (2021)
Effect of dexmedetomidine on sevoflurane-induced neurodegeneration in neonatal rats
Jeong-Rim Lee et al.
BRITISH JOURNAL OF ANAESTHESIA (2021)
Dexmedetomidine Mitigated NLRP3-Mediated Neuroinflammation via the Ubiquitin-Autophagy Pathway to Improve Perioperative Neurocognitive Disorder in Mice
Lieliang Zhang et al.
FRONTIERS IN PHARMACOLOGY (2021)
PSD-95 protects synapses from β-amyloid
Kim Dore et al.
CELL REPORTS (2021)
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)
Daniel J. Klionsky et al.
AUTOPHAGY (2021)
Dexmedetomidine Protects Against Oxygen-Glucose Deprivation-Induced Injury Through Inducing Astrocytes Autophagy via TSC2/mTOR Pathway
Chen Zhu et al.
NEUROMOLECULAR MEDICINE (2020)
Dexmedetomidine Protects Against Lipopolysaccharide-Induced Acute Kidney Injury by Enhancing Autophagy Through Inhibition of the PI3K/AKT/mTOR Pathway
Yuan Zhao et al.
FRONTIERS IN PHARMACOLOGY (2020)
Dexmedetomidine Provides Protection Against Hippocampal Neuron Apoptosis and Cognitive Impairment in Mice with Alzheimer's Disease by Mediating the miR-129/YAP1/JAG1 Axis
Weiying Sun et al.
MOLECULAR NEUROBIOLOGY (2020)
Orientin Improves Cognition by Enhancing Autophagosome Clearance in an Alzheimer's Mouse Model
Yi Zhong et al.
JOURNAL OF MOLECULAR NEUROSCIENCE (2019)
Autophagy Modulation as a Treatment of Amyloid Diseases
Zoe Mputhia et al.
MOLECULES (2019)
The recovery from transient cognitive dysfunction induced by propofol was associated with enhanced autophagic flux in normal healthy adult mice
Sooyoung Cho et al.
BRAIN RESEARCH (2018)
Autophagic Degradation Deficit Involved in Sevoflurane-Induced Amyloid Pathology and Spatial Learning Impairment in APP/PS1 Transgenic Mice
Pengcheng Geng et al.
FRONTIERS IN CELLULAR NEUROSCIENCE (2018)
Administration of Dexmedetomidine inhibited NLRP3 inflammasome and microglial cell activities in hippocampus of traumatic brain injury rats
Bin Zheng et al.
BIOSCIENCE REPORTS (2018)
Promoting the clearance of neurotoxic proteins in neurodegenerative disorders of ageing
Barry Boland et al.
NATURE REVIEWS DRUG DISCOVERY (2018)
Dexmedetomidine Protects Mouse Brain from Ischemia-Reperfusion Injury via Inhibiting Neuronal Autophagy through Up-Regulating HIF-1α
Cong Luo et al.
FRONTIERS IN CELLULAR NEUROSCIENCE (2017)
Dexmedetomidine-Induced Neuroapoptosis Is Dependent on Its Cumulative Dose
Jia-Ren Liu et al.
ANESTHESIA AND ANALGESIA (2016)
Autophagy flux in CA1 neurons of Alzheimer hippocampus: Increased induction overburdens failing lysosomes to propel neuritic dystrophy
Matteo Bordi et al.
AUTOPHAGY (2016)
p62 links the autophagy pathway and the ubiqutin-proteasome system upon ubiquitinated protein degradation
Wei Jing Liu et al.
CELLULAR & MOLECULAR BIOLOGY LETTERS (2016)
Effect of dexmedetomidine on postoperative cognitive dysfunction in elderly patients after general anaesthesia: A meta-analysis
Chengmao Zhou et al.
JOURNAL OF INTERNATIONAL MEDICAL RESEARCH (2016)
Dose response of dexmedetomidine-induced resistance to hypoxia in mice
Wanying Pan et al.
MOLECULAR MEDICINE REPORTS (2016)
LAMP-2 is required for incorporating syntaxin-17 into autophagosomes and for their fusion with lysosomes
Virginie Hubert et al.
BIOLOGY OPEN (2016)
Intracerebroventricular Injection of Amyloid-β Peptides in Normal Mice to Acutely Induce Alzheimer-like Cognitive Deficits
Hye Yun Kim et al.
JOVE-JOURNAL OF VISUALIZED EXPERIMENTS (2016)
Dexmedetomidine: A Review of Its Use for Sedation in the Intensive Care Setting
Gillian M. Keating
DRUGS (2015)
Therapeutic targeting of autophagy in neurodegenerative and infectious diseases
David C. Rubinsztein et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2015)
LC3-and p62-based biochemical methods for the analysis of autophagy progression in mammalian cells
Peidu Jiang et al.
METHODS (2015)
Sigma-1 (σ1) receptor deficiency reduces β-amyloid25-35-induced hippocampal neuronal cell death and cognitive deficits through suppressing phosphorylation of the NMDA receptor NR2B
Jun Yin et al.
NEUROPHARMACOLOGY (2015)
Calcium/calmodulin-dependent kinase II and Alzheimer's disease
Anshua Ghosh et al.
MOLECULAR BRAIN (2015)
PI3K/AKT/mTOR/p70S6K Pathway Is Involved in Aβ25-35-Induced Autophagy
Shengnuo Fan et al.
BIOMED RESEARCH INTERNATIONAL (2015)
Mesenchymal stem cells enhance autophagy and increase beta-amyloid clearance in Alzheimer disease models
Jin Young Shin et al.
AUTOPHAGY (2014)
The role of autophagy in neurodegenerative disease
Ralph A. Nixon
NATURE MEDICINE (2013)
Aβ Secretion and Plaque Formation Depend on Autophagy
Per Nilsson et al.
CELL REPORTS (2013)
Proteases in autophagy
Vitaliy Kaminskyy et al.
BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS (2012)
Reduced cathepsins B and D cause impaired autophagic degradation that can be almost completely restored by overexpression of these two proteases in Sap C-deficient fibroblasts
Massimo Tatti et al.
HUMAN MOLECULAR GENETICS (2012)
Dysregulated phosphorylation of Ca2+/calmodulin-dependent protein kinase II-α in the hippocampus of subjects with mild cognitive impairment and Alzheimer's disease
Lindsay C. Reese et al.
JOURNAL OF NEUROCHEMISTRY (2011)
The amyloid cascade hypothesis for Alzheimer's disease: an appraisal for the development of therapeutics
Eric Karran et al.
NATURE REVIEWS DRUG DISCOVERY (2011)
Autophagy failure in Alzheimer's disease-locating the primary defect
Ralph A. Nixon et al.
NEUROBIOLOGY OF DISEASE (2011)
Methods in Mammalian Autophagy Research
Noboru Mizushima et al.
CELL (2010)
Abeta42-Induced Neurodegeneration via an Age-Dependent Autophagic-Lysosomal Injury in Drosophila
Daijun Ling et al.
PLOS ONE (2009)
Electroencephalogram spindle activity during dexmedetomidine sedation and physiological sleep
E. Huupponen et al.
ACTA ANAESTHESIOLOGICA SCANDINAVICA (2008)
Autophagy in the pathogenesis of disease
Beth Levine et al.
CELL (2008)
Autophagy induction and autophagosome clearance in neurons: Relationship to autophagic pathology in Alzheimer's disease
Barry Boland et al.
JOURNAL OF NEUROSCIENCE (2008)
Autophagy fights disease through cellular self-digestion
Noboru Mizushima et al.
NATURE (2008)
Aβ25-35 induces presynaptic changes in organotypic hippocampal slice cultures
Eun Cheng Suh et al.
NEUROTOXICOLOGY (2008)
p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy
Serhiy Pankiv et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Autophagic stress in neuronal injury and disease
Charleen T. Chu
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2006)
Reduction of NRI and phosphorylated Ca2+/calmodulin-dependent protein kinase II levels in Alzheimer's disease
N Amada et al.
NEUROREPORT (2005)
Macroautophagy -: a novel β-amyloid peptide-generating pathway activated in Alzheimer's disease
WH Yu et al.
JOURNAL OF CELL BIOLOGY (2005)
The apoptosis/autophagy paradox:: autophagic vacuolization before apoptotic death
RA González-Polo et al.
JOURNAL OF CELL SCIENCE (2005)
PSD-95 regulates synaptic transmission and plasticity in rat cerebral cortex
JC Béïque et al.
JOURNAL OF PHYSIOLOGY-LONDON (2003)
Lack of PSD-95 drives hippocampal neuronal cell death through activation of an αCaMKII transduction pathway
F Gardoni et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2002)
Progressive, age-related behavioral impairments in transgenic mice carrying both mutant amyloid precursor protein and presenilin-1 transgenes
GW Arendash et al.
BRAIN RESEARCH (2001)
The effects of increasing plasma concentrations of dexmedetomidine in humans
TJ Ebert et al.
ANESTHESIOLOGY (2000)