Glutamatergic neurometabolite levels in the caudate are associated with the ability of rhythm production

IntroductionGlutamatergic neurometabolites play important roles in the basal ganglia, a hub of the brain networks involved in musical rhythm processing. We aimed to investigate the relationship between rhythm processing abilities and glutamatergic neurometabolites in the caudate. MethodsWe aquired Glutamatergic function in healthy individuals employing proton magnetic resonance spectroscopy. We targeted the right caudate and the dorsal anterior cingulate cortex (dACC) as a control region. Rhythm processing ability was assessed by the Harvard Beat Assessment Test (H-BAT). ResultsWe found negative correlations between the production part of the Beat Saliency Test in the H-BAT and glutamate and glutamine levels in the caudate (r = -0.693, p = 0.002) whereas there was no such association in the dACC. ConclusionThese results suggest that higher glutamatergic neurometabolite levels in the caudate may contribute to rhythm processing, especially the ability to produce meter in music precisely.

Automated summary

This study investigated the relationship between rhythm processing abilities and glutamatergic neurometabolites in the caudate. The results showed a negative correlation between glutamate and glutamine levels in the caudate and the production part of the Beat Saliency Test. This suggests that higher levels of glutamatergic neurometabolites in the caudate may contribute to rhythm processing, particularly the ability to produce meter in music precisely.