4.8 Article

Bio-inspired metal ions regulate the structure evolution of self-assembled peptide-based nanoparticles

Journal

NANOSCALE
Volume 8, Issue 29, Pages 14078-14083

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c6nr03580a

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Funding

  1. National Natural Science Foundation of China [51573031, 21374026]
  2. National Basic Research Program of China (973 Program) [2013CB932701]
  3. Program of Beijing Municipal Science and Technology [Z141100000214008]

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We report an assembly and transformation process of a supramolecular module, BP-KLVFF-RGD (BKR) in solution and on specific living cell surfaces for imaging and treatment. The BKR self-assembled into nanoparticles, which further transformed into nanofibers in situ induced by coordination with Ca2+ ions.

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