Journal
NANOSCALE
Volume 8, Issue 45, Pages 18876-18881Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c6nr08055c
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Funding
- Natural Science Foundation of China [21303145]
- Natural Science Foundation of Fujian Province of China [2014J01063]
- A*STAR Personal Care Grant [1325400026]
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A tumor active targeting beta-cyclodextrin based nanocarrier beta-NC-OEI-SS-FA was designed by the modification of star shaped cationic derivatives beta-NC-OEI with folic acid through a disulfide bond, to co-deliver chemotherapeutic paclitaxel and the Nur77 gene for overcoming Bcl-2 mediated non-pump resistance by an enemy to friend strategy for potential drug resistant cancer therapy.
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