☆ 4.6 Article

Clinical characteristics and outcomes of acute kidney injury in patients with severe fever with thrombocytopenia syndrome

FRONTIERS IN MICROBIOLOGY (2023)

Related references

Note: Only part of the references are listed.

Article Immunology

A High Viral Load in Urine Correlates With Acute Kidney Injury and Poor Outcomes in Hospitalized Patients With Severe Fever With Thrombocytopenia Syndrome: A Noninvasive and Convenient Prognostic Marker

Qian Zhang et al.

Summary: This study found that the level of SFTSV in urine is associated with renal damage and mortality in SFTS patients. The level of SFTSV in urine can serve as a novel convenient and noninvasive predictive biomarker for the incidence of AKI and poor outcome in patients with SFTS. Additionally, the study revealed that SFTSV present in urine samples can infect humans.

OPEN FORUM INFECTIOUS DISEASES (2023)

Add to Collection

Article Virology

Viral Load as a Factor Affecting the Fatality of Patients Suffering from Severe Fever with Thrombocytopenia Syndrome

Heyon-Na Jo et al.

Summary: The study analyzed the clinical characteristics and the effect of viral RNA loads on fatality in 56 patients with severe fever with thrombocytopenia syndrome (SFTS). Age and viral copy numbers were found to be important factors affecting survival rates. Viral RNA loads can be useful markers for the clinical prediction of mortality and survival in SFTS patients.

VIRUSES-BASEL (2022)

Add to Collection

Article Virology

Nonstructural Protein NSs Activates Inflammasome and Pyroptosis through Interaction with NLRP3 in Human Microglial Cells Infected with Severe Fever with Thrombocytopenia Syndrome Bandavirus

Chengfeng Gao et al.

Summary: Infection with SFTS virus can activate the NLRP3 inflammasome and induce IL-1 beta secretion in the brains of infected newborn mice. This study reveals a novel mechanism by which SFTSV dysregulates host responses through its nonstructural protein, providing insights into viral neuropathogenesis in SFTS patients.

JOURNAL OF VIROLOGY (2022)

Add to Collection

Review Infectious Diseases

Clinical laboratory parameters and fatality of Severe fever with thrombocytopenia syndrome patients: A systematic review and meta-analysis

Yao Wang et al.

Summary: This systematic review found that clinical laboratory parameters of SFTS patients are associated with the risk of mortality. Abnormal levels of viral load, platelet count, coagulation function, and liver function significantly increase the risk of death in SFTS patients.

PLOS NEGLECTED TROPICAL DISEASES (2022)

Add to Collection

Review Physiology

Biomarkers and predicting acute kidney injury

Friedrich C. Luft

Summary: This article discusses the conversion of biomarkers into reliable laboratory tests, examining both early and recently propagated biomarkers. It also proposes the need for faster and better tests that can reflect decreased renal function and predict increased AKI risk.

ACTA PHYSIOLOGICA (2021)

Add to Collection

Article Gastroenterology & Hepatology

Progression of Stage 2 and 3 Acute Kidney Injury in Patients With Decompensated Cirrhosis and Ascites

Florence Wong et al.

Summary: The study showed that in patients with cirrhosis, the development of stages 2 or 3 AKI may be associated with advanced liver disease and second infection, leading to decreased 30-day transplant-free survival. Preventing AKI progression in these patients could potentially improve their outcomes.

CLINICAL GASTROENTEROLOGY AND HEPATOLOGY (2021)

Add to Collection

Review Virology

Covid-19 and kidney injury: Pathophysiology and molecular mechanisms

Elham Ahmadian et al.

Summary: Kidney involvement in Covid-19 mainly presents as proteinuria and acute kidney injury, with mechanisms including direct viral infection of kidney cells, immune dysregulation, and other factors. Understanding the pathophysiology is crucial for developing effective therapeutic strategies.

REVIEWS IN MEDICAL VIROLOGY (2021)

Add to Collection

Article Infectious Diseases

Clinical features of severe fever with thrombocytopenia syndrome and analysis of risk factors for mortality

Feng He et al.

Summary: This study retrospectively analyzed data from SFTS patients diagnosed by laboratory examination, and identified independent risk factors for mortality including consciousness disorder, hemorrhagic manifestations, renal dysfunction, AST ≥ 400 U/L, and LDH ≥ 1000 U/L. These factors should be closely monitored in clinical treatment to prevent fatal outcomes.

BMC INFECTIOUS DISEASES (2021)

Add to Collection

Article Biochemistry & Molecular Biology

The Nonstructural Protein NSs of Severe Fever with Thrombocytopenia Syndrome Virus Causes a Cytokine Storm through the Hyperactivation of NF-κB

Jumana Khalil et al.

Summary: The severe fever with thrombocytopenia syndrome (SFTS) virus (SFTSV) NSs protein promotes the induction of a fatal cytokine storm through inhibiting TBK1 protein, which activates NF-kappa B signaling in the host. Therefore, NF-kappa B may serve as a potential therapeutic target for SFTS.

MOLECULAR AND CELLULAR BIOLOGY (2021)

Add to Collection

Article Public, Environmental & Occupational Health

Clinical Progress and Risk Factors for Death from Severe Fever with Thrombocytopenia Syndrome: A Multihospital Retrospective Investigation in Anhui, China

Lei Gong et al.

Summary: Complications like multiple-organ failure, central nervous system abnormalities, and disseminated intravascular coagulation are commonly associated with mortality in severe fever with thrombocytopenia syndrome (SFTS) patients. Laboratory parameters such as alanine transaminase, prothrombin time, and uric acid levels are generally higher in fatal cases.

AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE (2021)

Add to Collection

Article Multidisciplinary Sciences

A longitudinal sampling study of transcriptomic and epigenetic profiles in patients with thrombocytopenia syndrome

Yafen Wang et al.

Summary: The study characterizes transcriptomic and epigenetic changes in patients infected with SFTSV, correlating them with clinical parameters to enhance understanding of disease progression. This research suggests that monitoring specific indicators may guide personalized treatment for SFTS.

NATURE COMMUNICATIONS (2021)

Add to Collection

Review Urology & Nephrology

Pathophysiology of COVID-19-associated acute kidney injury

Matthieu Legrand et al.

Summary: Acute kidney injury (AKI) is a common complication of COVID-19, and potential mechanisms for COVID-19-associated AKI include systemic haemodynamic instability, local immune cell infiltration, and endothelial injury, which may lead to impaired kidney function.

NATURE REVIEWS NEPHROLOGY (2021)

Add to Collection

Article Critical Care Medicine

ANALYSIS OF SEVERE FEVER WITH THROMBOCYTOPENIA SYNDROME IN CRITICAL ILL PATIENTS IN CENTRAL CHINA

Qi Nie et al.

SHOCK (2020)

Add to Collection

Article Immunology

Direct Transmission of Severe Fever with Thrombocytopenia Syndrome Virus from Domestic Cat to Veterinary Personnel

Atsushi Yamanaka et al.

EMERGING INFECTIOUS DISEASES (2020)

Add to Collection

Article Medicine, General & Internal

The Incidence of Acute Kidney In u and Associated Hospital Mortality A Retrospective Cohort Study of Over 100 000 Patients at Berlin's Charite Hospital

Dmytro Khadzhynov et al.

DEUTSCHES ARZTEBLATT INTERNATIONAL (2019)

Add to Collection

Review Pharmacology & Pharmacy

Acute kidney injury overview: From basic findings to new prevention and therapy strategies

Sabrina Ribeiro Gonsalez et al.

PHARMACOLOGY & THERAPEUTICS (2019)

Add to Collection

Article Multidisciplinary Sciences

Severe Fever with Thrombocytopenia Syndrome Phlebovirus causes lethal viral hemorrhagic fever in cats

Eun-sil Park et al.

SCIENTIFIC REPORTS (2019)

Add to Collection

Article Infectious Diseases

A nomogram to predict mortality in patients with severe fever with thrombocytopenia syndrome at the early stage-A multicenter study in China

Lin Wang et al.

PLOS NEGLECTED TROPICAL DISEASES (2019)

Add to Collection

Article Infectious Diseases

Analysis of clinical features and early warning indicators of death from severe fever with thrombocytopenia syndrome

Xiaowen Xu et al.

INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES (2018)

Add to Collection

Review Urology & Nephrology

Phenotyping of Acute Kidney Injury: Beyond Serum Creatinine

Dennis G. Moledina et al.

SEMINARS IN NEPHROLOGY (2018)

Add to Collection

Article Virology

Multiple organ involvement in severe fever with thrombocytopenia syndrome: an immunohistochemical finding in a fatal case

Shibo Li et al.

VIROLOGY JOURNAL (2018)

Add to Collection

Article Infectious Diseases

A scoring model for predicting prognosis of patients with severe fever with thrombocytopenia syndrome

Bei Jia et al.

PLOS NEGLECTED TROPICAL DISEASES (2017)

Add to Collection

Article Urology & Nephrology

Performance of Serum Creatinine and Kidney Injury Biomarkers for Diagnosing Histologic Acute Tubular Injury

Dennis G. Moledina et al.

AMERICAN JOURNAL OF KIDNEY DISEASES (2017)

Add to Collection

Article Virology

The prospective evaluation of viral loads in patients with severe fever with thrombocytopenia syndrome

Zhen-Dong Yang et al.

JOURNAL OF CLINICAL VIROLOGY (2016)

Add to Collection

Article Virology

Meta-analysis of the clinical and laboratory parameters of SFTS patients in China

Miao-miao Liu et al.

VIROLOGY JOURNAL (2016)

Add to Collection

Article Infectious Diseases

Severe fever with thrombocytopenia syndrome bunyavirus-related human encephalitis

Ning Cui et al.

JOURNAL OF INFECTION (2015)

Add to Collection

Review Infectious Diseases

Severe fever with thrombocytopenia syndrome, an emerging tick-borne zoonosis

Quan Liu et al.

LANCET INFECTIOUS DISEASES (2014)

Add to Collection

Review Virology

Systematic review of severe fever with thrombocytopenia syndrome: virology, epidemiology, and clinical characteristics

Shelan Liu et al.

REVIEWS IN MEDICAL VIROLOGY (2014)

Add to Collection

Article Immunology

Severe Fever with Thrombocytopenia Syndrome, Shandong Province, China, 2011

Hong-Ling Wen et al.

EMERGING INFECTIOUS DISEASES (2014)

Add to Collection

Editorial Material Urology & Nephrology

KDOQI US Commentary on the 2012 KDIGO Clinical Practice Guideline for Acute Kidney Injury

Paul M. Palevsky et al.

AMERICAN JOURNAL OF KIDNEY DISEASES (2013)

Add to Collection

Article Immunology

Case-Fatality Ratio and Effectiveness of Ribavirin Therapy Among Hospitalized Patients in China Who Had Severe Fever With Thrombocytopenia Syndrome

Wei Liu et al.

CLINICAL INFECTIOUS DISEASES (2013)

Add to Collection

Review Anesthesiology

Novel biomarkers of acute kidney injury and failure: clinical applicability

J. Martensson et al.

BRITISH JOURNAL OF ANAESTHESIA (2012)

Add to Collection

Article Immunology

Hemorrhagic Fever Caused by a Novel Bunyavirus in China: Pathogenesis and Correlates of Fatal Outcome

Yong-Zhen Zhang et al.

CLINICAL INFECTIOUS DISEASES (2012)

Add to Collection

Article Biotechnology & Applied Microbiology

Infection and pathogenesis of Huaiyangshan virus (a novel tick-borne bunyavirus) in laboratory rodents

Xiao-Ping Chen et al.

JOURNAL OF GENERAL VIROLOGY (2012)

Add to Collection

Article Medicine, General & Internal

Acute kidney injury

Rinaldo Bellomo et al.

LANCET (2012)

Add to Collection

Article Multidisciplinary Sciences

Pathogenesis of emerging severe fever with thrombocytopenia syndrome virus in C57/BL6 mouse model

Cong Jin et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)

Add to Collection

Article Immunology

A Family Cluster of Infections by a Newly Recognized Bunyavirus in Eastern China, 2007: Further Evidence of Person-to-Person Transmission

Chang-jun Bao et al.

CLINICAL INFECTIOUS DISEASES (2011)

Add to Collection

Article Medicine, General & Internal

Fever with Thrombocytopenia Associated with a Novel Bunyavirus in China

Xue-Jie Yu et al.

NEW ENGLAND JOURNAL OF MEDICINE (2011)

Add to Collection

Review Critical Care Medicine

Urinary biomarkers in septic acute kidney injury

Sean M. Bagshaw et al.

INTENSIVE CARE MEDICINE (2007)

Add to Collection

© Peeref 2019-2024. All rights reserved.