Related references
Note: Only part of the references are listed.
Article
Food Science & Technology
Heinrich Schulte-Baukloh et al.
Summary: In this study, a new app-controlled automated diary pod was used to document the precise onset of the effect of OnabotA-DI in real time. The results showed that the effect of OnabotA-DI started from the first postoperative days and had similar changes in day and night micturition frequencies.
Article
Food Science & Technology
Carlo M. Bertoncelli et al.
Summary: This study developed a prediction model to identify the prognostic phenotype of children with cerebral palsy who require neurotoxin injections. Results showed that upper limbs and trunk muscle tone disorders, spasticity, dystonia, and hip dysplasia were strongly associated with neurotoxin treatments.
Article
Food Science & Technology
Valentina Mastrorilli et al.
Summary: Xeomin is a commercial formulation of botulinum neurotoxin type A used for treating neurological disorders. This study found that Xeomin had similar pharmacological and therapeutic effects as laboratory purified botulinum neurotoxin A in a preclinical spinal cord injury model, although with slightly less efficacy.
Article
Food Science & Technology
Marie Beret et al.
Summary: This study investigated the effect of intra-articular injection of botulinum toxin A (BoNT/A) in an animal model of temporomandibular joint osteoarthritis. The results showed that rats receiving intra-articular BoNT/A had a significant decrease in pain compared to those receiving placebo, starting from day 7 and lasting until day 21. Histological and radiographic analysis also demonstrated a reduction in joint inflammation in the BoNT/A group. The study suggests that intra-articular BoNT/A injection can alleviate pain and inflammation in temporomandibular osteoarthritis.
Article
Food Science & Technology
Joerg Mueller et al.
Summary: Botulinum toxin injections into salivary glands can be used for the treatment of sialorrhea and also protect the glands from harm caused by radioligand cancer therapies. In this study, increasing the dosage of IncoA combined with transdermal scopolamine successfully reduced the radioligand uptake in the salivary glands of patients with metastasized prostate cancer. The treatment was well tolerated and had minimal side effects.
Article
Food Science & Technology
Kyu-Ho Yi et al.
Summary: The injection points for the serratus anterior muscle were suggested based on the intramuscular neural distribution, and it was found that the largest arborization patterns of the muscle were in the fifth to ninth rib portion.
Review
Food Science & Technology
Kyu-Ho Yi et al.
Summary: This study assesses the anatomical aspects of injecting botulinum neurotoxin into nose muscles and provides recommendations for injection points and techniques to improve the removal of wrinkles in the nose area and support a more precise procedure.
Review
Food Science & Technology
Lorenzo Lippi et al.
Summary: This systematic review examines the multidimensional effects of botulinum toxin (BoNT) treatment on neuropathic pain. The analysis of 12 studies suggests that BoNT administration is effective in relieving pain and improving health-related quality of life. BoNT treatment has the potential to be an effective approach in the comprehensive management of neuropathic pain. Further research should focus on optimizing therapeutic protocols in terms of both effectiveness and cost-efficiency.
Article
Food Science & Technology
Xin Li et al.
Summary: This study introduced botulinum toxin-A (BTX-A) into dental occlusal treatment for short-faced patients, providing a new minimally invasive therapy perspective. The study found significant effects of BTX-A on masseter muscle thickness, occlusal height, occlusal curves, and temporomandibular joint spaces. The pilot study suggests that BTX-A may serve as an adjuvant treatment for occlusal therapy in short-faced patients.
Article
Food Science & Technology
Victor Ricardo Manuel Munoz-Lora et al.
Summary: Both abobotulinumtoxinA and onabotulinumtoxinA have similar analgesic effects on the antigen-induced persistent immunogenic hypersensitivity of the temporomandibular joint in rats, possibly by inhibiting central neuronal and astroglial activation.
Article
Food Science & Technology
Fiona Carolin Wenninger et al.
Summary: The study found no significant difference in the frequency of hemorrhagic side effects of BoNT/A treatment for BEB and HFS between patients taking antithrombotic drugs and the control group. Even among different subgroups of antithrombotic drugs, there was no significant variation in the hematoma frequency.
Review
Food Science & Technology
Parisa Gazerani
Summary: There is still no approved product for the anti-itch indication of botulinum neurotoxins (BoNTs) after two decades of research. Most studies focus on the off-label use of BoNTs for various itchy conditions, with controversial results from few randomized clinical trials. To obtain approval for the anti-pruritic indication of BoNTs, higher levels of evidence are required through well-designed studies.
Review
Food Science & Technology
Siro Luvisetto
Summary: In recent years, studies have shown the significant therapeutic use of botulinum neurotoxins (BoNTs) in various motor and autonomic disorders. BoNTs exert their therapeutic effects by selectively cleaving specific sites of the SNARE protein complex, interfering with neural transmission. They can block the release of neurotransmitters and neuromodulators and affect glial cell function. The exact mechanisms are not fully understood, but BoNTs can inhibit spinal glial cell activation and promote peripheral regeneration. Overall, BoNTs have important therapeutic implications for conditions involving glial cell activation.
Editorial Material
Food Science & Technology
Siro Luvisetto
