Journal
NANOSCALE
Volume 8, Issue 13, Pages 6981-6985Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c5nr07588b
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- Nanyang Technological University (NTU)
- Lee Kong Chian School of Medicine (LKCMedicine)
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Core-shell type 'nanoghosts' were synthesized with a drug-loaded biodegradable PLGA core and a monocyte cell membrane-derived shell. The nanoghosts were monodisperse with an average size <200 nm, and showed good serum stability for 120 h. Doxorubicin-loaded nanoghosts showed greater cellular uptake and cytotoxicity compared to non-coated nanoparticle controls in metastatic MCF-7 breast cancer cell lines.
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