Planting the seeds for a forest of RNAi pathways

Cells from most eukaryotic species make several different types of small interfering RNAs. Pioneering work in plants, published in PLOS Biology almost 20 years ago, established a framework to understand how multiple RNA interference pathways can regulate the genome in parallel.

Automated summary

Cells from most eukaryotic species produce various types of small interfering RNAs. Pioneering research in plants, published in PLOS Biology nearly 20 years ago, established a framework for understanding how multiple RNA interference pathways can simultaneously regulate the genome.