☆ 4.7 Article

A Large Genetic Causal Analysis of the Gut Microbiota and Urological Cancers: A Bidirectional Mendelian Randomization Study

NUTRIENTS (2023)

Related references

Note: Only part of the references are listed.

Article Urology & Nephrology

Smoking and Risk of Prostate Cancer and Prostate Cancer Death: A Pooled Study

Sylvia H. J. Jochems et al.

Summary: This study investigated the association between smoking and prostate cancer (PCa) risk and death among 351,448 men in Sweden. Results showed that smoking was associated with a lower risk of PCa incidence, particularly for low-risk PCa. However, smoking was associated with an increased risk of PCa death. Smoking in combination with obesity further affected the risk of PCa.

EUROPEAN UROLOGY (2023)

Add to Collection

Article Multidisciplinary Sciences

FinnGen provides genetic insights from a well-phenotyped isolated population

Mitja Kurki et al.

Summary: Population isolates, like those in Finland, provide valuable insights for genetic research due to the concentration of deleterious alleles in low-frequency variants. FinnGen aims to study the genome and health data of 500,000 Finnish individuals, enabling the identification of new associations and the exploration of their implications for common diseases. The study identified 30 new associations and 2,733 genome-wide significant associations, highlighting the power of bottlenecked populations in uncovering disease biology.

NATURE (2023)

Add to Collection

Article Medicine, General & Internal

Cross-talks between gut microbiota and tobacco smoking: a two-sample Mendelian randomization study

Jiayao Fan et al.

Summary: This study utilized summary-level data from genome-wide association studies (GWAS) to investigate the causal association between gut microbiota and tobacco smoking. The results showed that smoking may influence the abundance of certain gut microbes, and the abundance of certain gut microbes may also be the result of smoking behavior. These findings are important for understanding the impact of smoking on gut microbiota and the potential role of specific gut microbes in smoking behavior.

BMC MEDICINE (2023)

Add to Collection

Article Medicine, General & Internal

Causal relationship between gut microbiota and cancers: a two-sample Mendelian randomisation study

Yiwen Long et al.

Summary: This study suggests a causal association between the gut microbiota and cancer, providing new insights for further research on the mechanisms and clinical implications of microbiota-mediated cancer.

BMC MEDICINE (2023)

Add to Collection

Review Radiology, Nuclear Medicine & Medical Imaging

Patients With Gray Zone PSA Levels: Application of Prostate MRI and MRS in the Diagnosis of Prostate Cancer

Xue Li et al.

Summary: This article presents a systematic review on the applications of MRI and MRS in detecting prostate cancer and clinically significant prostate cancer in men with PSA levels within the gray zone. The review shows that MRI and MRS have good performance in the prebiopsy diagnosis and guidance of prostate biopsy, leading to improved detection rates of prostate cancer and clinically significant prostate cancer.

JOURNAL OF MAGNETIC RESONANCE IMAGING (2023)

Add to Collection

Article Oncology

Obesity and main urologic cancers: Current systematic evidence, novel biological mechanisms, perspectives and challenges

Georgios Papavasileiou et al.

Summary: Urologic cancers account for a significant proportion of new cancer cases and deaths. There is evidence supporting a potential causal link between obesity and four common urologic cancers. Genetic studies have shown a possible association between obesity and kidney and bladder cancer, while biological mechanisms such as hormone levels and inflammation may contribute to this link. Potential therapeutic options for urologic cancers related to obesity include certain drugs and adipokine receptor agonists/antagonists.

SEMINARS IN CANCER BIOLOGY (2023)

Add to Collection

Review Oncology

Targeting c-Met in the treatment of urologic neoplasms: Current status and challenges

Pengxiao Su et al.

Summary: Currently, studies have found the involvement of c-Met in the epithelial-mesenchymal transition (EMT) of urologic neoplasms. The combination of hepatocyte growth factor (HGF) and c-Met promotes tumor cell mitosis, leading to cellular motility, angiogenesis, migration, invasion, and drug resistance. Therefore, c-Met targeting therapy shows great potential in urologic neoplasms. However, current clinical trials have not yielded significant results, highlighting the importance of studying the detailed mechanism of c-Met and developing innovative targeted drugs for effective clinical treatment.

FRONTIERS IN ONCOLOGY (2023)

Add to Collection

Review Biochemistry & Molecular Biology

Blood-based liquid biopsy: insights into early detection, prediction, and treatment monitoring of bladder cancer

Shijie Li et al.

Summary: Bladder cancer is a global clinical challenge characterized by late presentation, poor prognosis, and low survival rates. Traditional methods for diagnosis and monitoring, such as cystoscopy and tissue biopsy, have limitations and high costs. In recent years, liquid biopsies, specifically blood-based ones, have emerged as highly efficient methods for discovering biomarkers and monitoring tumor progression. Several liquid biopsy biomarkers have shown promising results in clinical applications, including early detection, residual disease detection, recurrence prediction, and therapy response.

CELLULAR & MOLECULAR BIOLOGY LETTERS (2023)

Add to Collection

Review Andrology

Emerging Relationship between the Gut Microbiome and Prostate Cancer

Makoto Matsushita et al.

Summary: The gut microbiota, influenced by both environmental and genetic factors, has been found to have a significant impact on human health. Research has shown a close association between the gut microbiome and various non-intestinal diseases, particularly in the field of cancer biology and therapy. Prostate cancer cells are directly affected by the microbiota in local tissues and urine, suggesting a relationship between prostate cancer cells and the gut microbiota. The bacterial composition of the gut microbiota differs depending on prostate cancer characteristics, such as histological grade and castration resistance. Additionally, certain intestinal bacteria have been shown to be involved in testosterone metabolism, indicating a potential influence on prostate cancer progression and treatment. Basic research suggests that the gut microbiome plays a crucial role in prostate cancer biology through microbial-derived metabolites and components. This review focuses on the emerging relationship between the gut microbiome and prostate cancer, referred to as the gut-prostate axis.

WORLD JOURNAL OF MENS HEALTH (2023)

Add to Collection

Article Oncology

Emerging genomic biomarkers for improving kidney, prostate, and bladder cancer health disparities outcomes

Khadijah A. Mitchell et al.

Summary: Advances in genomic and genetic technologies have improved health outcomes for urologic cancer patients. Race and ancestry are associated with kidney, prostate, and bladder cancer outcomes. Integrating population-specific genomic information with urologic cancer-specific characteristics can improve outcomes and reduce cancer health disparities.

UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS (2022)

Add to Collection

Article Gastroenterology & Hepatology

Cancer pharmacomicrobiomics: targeting microbiota to optimise cancer therapy outcomes

Nick Lung-Ngai Ting et al.

Summary: The relationship between gut microbiota and cancer treatment is crucial for enhancing therapeutic efficacy. Microbiota can be easily modified through various strategies, such as fecal microbiota transplantation, probiotics, and antibiotics. Studies have identified how microbes influence the pharmacokinetics and pharmacodynamics of cancer treatment. Clinical trials demonstrate the potential of microbiota modulation.

GUT (2022)

Add to Collection

Review Cell Biology

Use of Circular RNAs in Diagnosis, Prognosis and Therapeutics of Renal Cell Carcinoma

Rebeca Osca-Verdegal et al.

Summary: Renal cell carcinoma is the most common and deadliest type of kidney cancer. The clinical characteristics are unspecific, hindering the diagnostic process. Surgical resection remains the main treatment strategy, but most metastatic renal cell carcinomas are resistant to traditional treatment methods. Therefore, finding new biomarkers for early detection and treatment of renal cell carcinoma is essential.

FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2022)

Add to Collection

Article Genetics & Heredity

Integrated Analysis of the Fecal Metagenome and Metabolome in Bladder Cancer in a Chinese Population

Chuan Qin et al.

Summary: This study identified significant dysregulation of gut microbiomes and metabolites in Chinese bladder cancer patients, presenting potential causative relationships between gut dysbiosis, dysregulated metabolites, and bladder cancer. The integrative analysis revealed interactions between gut microbiota and metabolites as well as associations between specific gut microbiomes and metabolites.

GENES (2022)

Add to Collection

Article Microbiology

Gut-Testis Axis: Microbiota Prime Metabolome To Increase Sperm Quality in Young Type 2 Diabetes

Xiaowei Yan et al.

Summary: A10-FMT improves gut microbiota, liver function, and systemic environment, leading to better blood metabolome and favoring the testicular microenvironment for spermatogenesis. This helps to boost semen quality in individuals with T2D. The study highlights the potential of AOS-improved gut microbiota in treating T2D-related male subfertility.

MICROBIOLOGY SPECTRUM (2022)

Add to Collection

Review Chemistry, Analytical

State-of-the-Art Advances of Nanomedicine for Diagnosis and Treatment of Bladder Cancer

Chenfan Kong et al.

Summary: This article presents an overview of the new advancements in nano-platforms for the diagnosis and treatment of bladder cancer, including the potential of nanomedicine in reducing side effects, enhancing tumor inhibition effects, and overcoming drug resistance.

BIOSENSORS-BASEL (2022)

Add to Collection

Article Oncology

The influence of dysbiosis on kidney stones that risk up renal cell carcinoma (RCC)

Shruti Gupta et al.

Summary: Kidney stone is a common urological condition with increasing prevalence, associated with dietary habits, obesity, and diabetes mellitus. Patients with kidney stones are more prone to kidney tumors, and dysbiosis of the gut and urinary tract microbiome may contribute to the development of kidney stone disease. The variation in microbiome in human gut and urinary tract is linked to chronic kidney stone diseases and increased risks of papillary RCC.

SEMINARS IN CANCER BIOLOGY (2021)

Add to Collection

Article Public, Environmental & Occupational Health

Common Methodological Problems in Randomized Controlled Trials of Preventive Interventions

Christine M. Steeger et al.

Summary: Most preventive intervention RCTs have methodological weaknesses that need improvement to support causal inference claims of intervention effectiveness. Researchers should enhance reporting of methods and results to fully assess methodological quality and increase the credibility and usability of RCT findings.

PREVENTION SCIENCE (2021)

Add to Collection

Article Genetics & Heredity

Large-scale association analyses identify host factors influencing human gut microbiome composition

Alexander Kurilshikov et al.

Summary: The study revealed significant effects of host genetic variation on microbial composition, with the lactase (LCT) gene locus showing an age-dependent association with Bifidobacterium abundance. Other associations, while suggestive, were enriched for taxa with high heritability and for genes expressed in the intestine and brain.

NATURE GENETICS (2021)

Add to Collection

Article Medicine, Research & Experimental

Using Mendelian Randomization to Improve the Design of Randomized Trials

Brian A. Ference et al.

Summary: Randomized controlled trials and Mendelian randomization studies both utilize randomization to provide unbiased estimates of causal effects, but have distinct scientific objectives and study designs. Mendelian randomization studies cannot replace randomized trials but offer complementary information.

COLD SPRING HARBOR PERSPECTIVES IN MEDICINE (2021)

Add to Collection

Review Medicine, General & Internal

Focus on the Gut-Kidney Axis in Health and Disease

Elisavet Stavropoulou et al.

Summary: Recent technological advances have improved the identification of microbiota bacterial species and their impact on health and disease. Intestinal dysbiosis is closely linked to the development of various renal diseases and pathologies, with the gastrointestinal-kidney dialogue playing a significant role in their pathogenesis. Investigating this interconnection represents a cutting-edge area of research with potential implications for human health.

FRONTIERS IN MEDICINE (2021)

Add to Collection

Article Oncology

Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

Hyuna Sung et al.

Summary: The global cancer burden in 2020 saw an estimated 19.3 million new cancer cases and almost 10.0 million cancer deaths. Female breast cancer surpassed lung cancer as the most commonly diagnosed cancer, while lung cancer remained the leading cause of cancer death. These trends are expected to rise in 2040, with transitioning countries experiencing a larger increase compared to transitioned countries due to demographic changes and risk factors associated with globalization and a growing economy. Efforts to improve cancer prevention measures and provision of cancer care in transitioning countries will be crucial for global cancer control.

CA-A CANCER JOURNAL FOR CLINICIANS (2021)

Add to Collection

Article Multidisciplinary Sciences

Commensal bacteria promote endocrine resistance in prostate cancer through androgen biosynthesis

Nicolo Pernigoni et al.

Summary: The gut microbiota enriched for species capable of converting androgen precursors into active androgens was found to contribute to the onset of castration resistance in CRPC. Ablation of the gut microbiota by antibiotic therapy delayed the emergence of castration resistance in mice. Fecal microbiota transplantation from CRPC patients rendered mice resistant to castration.

SCIENCE (2021)

Add to Collection

Review Oncology

Prostate Microbiota and Prostate Cancer: A New Trend in Treatment

Bangwei Che et al.

Summary: Prostate cancer, one of the leading causes of death from malignant tumors, is influenced by various factors, with the microbiota potentially playing a significant role in its occurrence, development, and treatment.

FRONTIERS IN ONCOLOGY (2021)

Add to Collection

Article Oncology

The interplay of obesity, gut microbiome and diet in the immune check point inhibitors therapy era

Nikolaos Spyrou et al.

Summary: Immunotherapy has shown great promise in cancer treatment, but only a small percentage of patients exhibit lasting responses to immune checkpoint inhibitors. Factors such as obesity, host microbiome, and nutrition may play a role in influencing patients' response to immunotherapy, with emerging evidence suggesting that obese patients may actually benefit more from ICI therapy compared to those with a normal BMI. Further research is needed to explore how these factors can be leveraged to enhance the effectiveness of immunotherapy and potentially offer new therapeutic targets for cancer treatment.

SEMINARS IN CANCER BIOLOGY (2021)

Add to Collection

Article Oncology

Gut Microbiota-Derived Short-Chain Fatty Acids Promote Prostate Cancer Growth via IGF1 Signaling

Makoto Matsushita et al.

Summary: This study found that excessive intake of animal fat can change the composition of gut microbiota, leading to prostate cancer. By administering antibiotics, prostate cancer cell proliferation and IGFI levels can be inhibited, thus disrupting the growth of prostate cancer.

CANCER RESEARCH (2021)

Add to Collection

Article Oncology

The gut microbiota associated with high-Gleason prostate cancer

Makoto Matsushita et al.

Summary: Intestinal bacteria and SCFAs have been found to promote cancer growth in prostate cancer models, with specific bacterial taxa serving as potential markers for high-risk prostate cancer detection. Further research in this area may provide new insights into the pathogenesis of prostate cancer.

CANCER SCIENCE (2021)

Add to Collection

Review Oncology

Novel insights on gut microbiota manipulation and immune checkpoint inhibition in cancer (Review)

Silvia Vivarelli et al.

Summary: The composition of the gut microbiota (GM) plays a key role in cancer treatment, affecting the immune response to malignancies. Therefore, modulating the GM can improve the efficacy of immune checkpoint inhibitors (ICIs) therapy.

INTERNATIONAL JOURNAL OF ONCOLOGY (2021)

Add to Collection

Review Medicine, General & Internal

Prostate cancer

Shahneen Sandhu et al.

Summary: Management of prostate cancer is rapidly evolving with advances in understanding the genomic landscape, improved imaging methods, and personalised therapeutics targeting DNA repair pathways. The therapeutic framework for metastatic disease has shifted, with oligometastatic disease being evaluated for metastatic-directed therapies, and novel androgen pathway inhibitors showing significant survival benefits as first-line therapy for metastatic disease. Emerging research into molecular characterisation and novel therapeutics, such as targeted radioisotopes and immunotherapy, hold promise for improving patient outcomes.

LANCET (2021)

Add to Collection

Article Oncology

Gut Microbiota Dysbiosis Accelerates Prostate Cancer Progression Through Increased LPCAT1 Expression and Enhanced DNA Repair Pathways

Yufei Liu et al.

Summary: The study confirmed the abundance of Ruminococcus in the gut of CRPC individuals and mice receiving their fecal suspensions, revealing the promotive capability of Ruminococcus in PCa progression by upregulating LPCAT1 and DNA repair protein expressions. The bacterium and its downstream pathways may become potential targets for therapies for PCa in the future.

FRONTIERS IN ONCOLOGY (2021)

Add to Collection

Letter Medicine, General & Internal

Gut microbiota and health

K. C. Dilip et al.

POSTGRADUATE MEDICINE (2020)

Add to Collection

Review Nutrition & Dietetics

You Are What You Eat-The Relationship between Diet, Microbiota, and Metabolic Disorders-A Review

Malgorzata Moszak et al.

NUTRIENTS (2020)

Add to Collection

Review Nutrition & Dietetics

The Crosstalk between Prostate Cancer and Microbiota Inflammation: Nutraceutical Products Are Useful to Balance This Interplay?

Felice Crocetto et al.

NUTRIENTS (2020)

Add to Collection

Review Oncology

The human microbiome and its link in prostate cancer risk and pathogenesis

Paul Katongole et al.

INFECTIOUS AGENTS AND CANCER (2020)

Add to Collection

Article Microbiology

Gut microbiota: effect of pubertal status

Xin Yuan et al.

BMC MICROBIOLOGY (2020)

Add to Collection

Article Gastroenterology & Hepatology

Effects of dietary fat on gut microbiota and faecal metabolites, and their relationship with cardiometabolic risk factors: a 6-month randomised controlled-feeding trial

Yi Wan et al.

GUT (2019)

Add to Collection

Review Mathematical & Computational Biology

Meta-analysis and Mendelian randomization: A review

Jack Bowden et al.

RESEARCH SYNTHESIS METHODS (2019)

Add to Collection

Article Microbiology

Serum level of sex steroid hormone is associated with diversity and profiles of human gut microbiome

Ji-Hee Shin et al.

RESEARCH IN MICROBIOLOGY (2019)

Add to Collection

Article Nutrition & Dietetics

The association between gut microbiota composition and BMI in Chinese male college students, as analysed by next-generation sequencing

Yanrong Lv et al.

BRITISH JOURNAL OF NUTRITION (2019)

Add to Collection

Article Urology & Nephrology

The Microbiome and Prostate Cancer Risk

Karen M. Wheeler et al.

CURRENT UROLOGY REPORTS (2019)

Add to Collection

Review Urology & Nephrology

The Microbiome and Genitourinary Cancer: A Collaborative Review

Mark C. Markowski et al.

EUROPEAN UROLOGY (2019)

Add to Collection

Review Endocrinology & Metabolism

Obesity and cancer risk: Emerging biological mechanisms and perspectives

Konstantinos Avgerinos et al.

METABOLISM-CLINICAL AND EXPERIMENTAL (2019)

Add to Collection

Review Immunology

Microbiome Dependent Regulation of Tregs and Th17 Cells in Mucosa

Pushpa Pandiyan et al.

FRONTIERS IN IMMUNOLOGY (2019)

Add to Collection

Article Multidisciplinary Sciences

Gut microbiome modulates response to anti-PD-1 immunotherapy in melanoma patients

V. Gopalakrishnan et al.

SCIENCE (2018)

Add to Collection

Article Multidisciplinary Sciences

Gut microbiome influences efficacy of PD-1-based immunotherapy against epithelial tumors

Bertrand Routy et al.

SCIENCE (2018)

Add to Collection

Article Urology & Nephrology

Metabolic Biosynthesis Pathways Identified from Fecal Microbiome Associated with Prostate Cancer

Michael A. Liss et al.

EUROPEAN UROLOGY (2018)

Add to Collection

Article Genetics & Heredity

Detection of widespread horizontal pleiotropy in causal relationships inferred from Mendelian randomization between complex traits and diseases

Marie Verbanck et al.

NATURE GENETICS (2018)

Add to Collection

Review Urology & Nephrology

Mechanisms of BCG immunotherapy and its outlook for bladder cancer

Caroline Pettenati et al.

NATURE REVIEWS UROLOGY (2018)

Add to Collection

Article Oncology

Compositional differences in gastrointestinal microbiota in prostate cancer patients treated with androgen axis-targeted therapies

Karen S. Sfanos et al.

PROSTATE CANCER AND PROSTATIC DISEASES (2018)

Add to Collection

Review Cell Biology

The association of diet, gut microbiota and colorectal cancer: what we eat may imply what we get

Jia Yang et al.

PROTEIN & CELL (2018)

Add to Collection

Review Endocrinology & Metabolism

Sexual dimorphism of cardiometabolic dysfunction: Gut microbiome in the play?

Tzu-Wen L. Cross et al.

MOLECULAR METABOLISM (2018)

Add to Collection

Review Medicine, General & Internal

Prostate cancer screening with prostate-specific antigen (PSA) test: a systematic review and meta-analysis

Dragan Ilic et al.

BMJ-BRITISH MEDICAL JOURNAL (2018)

Add to Collection

Review Health Care Sciences & Services

A review of instrumental variable estimators for Mendelian randomization

Stephen Burgess et al.

STATISTICAL METHODS IN MEDICAL RESEARCH (2017)

Add to Collection

Article Microbiology

Oscillospira and related bacteria - From metagenomic species to metabolic features

Uri Gophna et al.

ENVIRONMENTAL MICROBIOLOGY (2017)

Add to Collection

Review Urology & Nephrology

Global Burden of Urologic Cancers, 1990-2013

Geolani W. Dy et al.

EUROPEAN UROLOGY (2017)

Add to Collection

Article Public, Environmental & Occupational Health

Robust inference in summary data Mendelian randomization via the zero modal pleiotropy assumption

Fernando Pires Hartwig et al.

INTERNATIONAL JOURNAL OF EPIDEMIOLOGY (2017)

Add to Collection

Review Medicine, General & Internal

The Diagnosis and Treatment of Prostate Cancer A Review

Mark S. Litwin et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2017)

Add to Collection

Editorial Material Medicine, General & Internal

Mendelian Randomization

Connor A. Emdin et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2017)

Add to Collection

Article Biochemical Research Methods

PhenoScanner: a database of human genotype-phenotype associations

James R. Staley et al.

BIOINFORMATICS (2016)

Add to Collection

Article Genetics & Heredity

Consistent Estimation in Mendelian Randomization with Some Invalid Instruments Using a Weighted Median Estimator

Jack Bowden et al.

GENETIC EPIDEMIOLOGY (2016)

Add to Collection

Review Medicine, General & Internal

Gut microbiota, obesity and diabetes

Elaine Patterson et al.

POSTGRADUATE MEDICAL JOURNAL (2016)

Add to Collection

Article Public, Environmental & Occupational Health

Mendelian randomization with invalid instruments: effect estimation and bias detection through Egger regression

Jack Bowden et al.

INTERNATIONAL JOURNAL OF EPIDEMIOLOGY (2015)

Add to Collection

Article Biochemistry & Molecular Biology

ECM1 regulates tumor metastasis and CSC-like property through stabilization of β-catenin

K-m Lee et al.

ONCOGENE (2015)

Add to Collection

Article Nutrition & Dietetics

Ten-Year Trends in Fiber and Whole Grain Intakes and Food Sources for the United States Population: National Health and Nutrition Examination Survey 2001-2010

Carla R. McGill et al.

NUTRIENTS (2015)

Add to Collection

Editorial Material Medicine, General & Internal

UK Biobank: An Open Access Resource for Identifying the Causes of a Wide Range of Complex Diseases of Middle and Old Age

Cathie Sudlow et al.

PLOS MEDICINE (2015)

Add to Collection

Review Oncology

The Global Burden of Cancer 2013 Global Burden of Disease Cancer Collaboration

Christina Fitzmaurice et al.

JAMA ONCOLOGY (2015)

Add to Collection

Article Oncology

Extracellular matrix protein 1 regulates cell proliferation and trastuzumab resistance through activation of epidermal growth factor signaling

Kyung-min Lee et al.

BREAST CANCER RESEARCH (2014)

Add to Collection

Article Genetics & Heredity

Mendelian Randomization Analysis With Multiple Genetic Variants Using Summarized Data

Stephen Burgess et al.

GENETIC EPIDEMIOLOGY (2013)

Add to Collection

Review Endocrinology & Metabolism

Observational research - opportunities and limitations

Edward J. Boyko

JOURNAL OF DIABETES AND ITS COMPLICATIONS (2013)

Add to Collection

Article Radiology, Nuclear Medicine & Medical Imaging

Metastatic Renal Cell Carcinoma: Radiologic Findings and Assessment of Response to Targeted Antiangiogenic Therapy by Using Multidetector CT

Blanca Pano Brufau et al.

RADIOGRAPHICS (2013)

Add to Collection

Review Microbiology

Microbiome and Malignancy

Claudia S. Plottel et al.

CELL HOST & MICROBE (2011)

Add to Collection

Article Public, Environmental & Occupational Health

Avoiding bias from weak instruments in Mendelian randomization studies

Stephen Burgess et al.

INTERNATIONAL JOURNAL OF EPIDEMIOLOGY (2011)

Add to Collection

Article Endocrinology & Metabolism

High-Fat Diet Increases NF-κB Signaling in the Prostate of Reporter Mice

Eugene V. Vykhovanets et al.

PROSTATE (2011)

Add to Collection

Article Cell Biology

Extracellular Matrix Degradation and Remodeling in Development and Disease

Pengfei Lu et al.

COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2011)

Add to Collection

Review Multidisciplinary Sciences

Has the Microbiota Played a Critical Role in the Evolution of the Adaptive Immune System?

Yun Kyung Lee et al.

SCIENCE (2010)

Add to Collection

Article Oncology

Prostate-specific antigen levels in the United States: Implications of various definitions for abnormal

HG Welch et al.

JOURNAL OF THE NATIONAL CANCER INSTITUTE (2005)

Add to Collection

Article Multidisciplinary Sciences

Statistical significance for genomewide studies

JD Storey et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)

Add to Collection

Article Public, Environmental & Occupational Health

'Mendelian randomization': can genetic epidemiology contribute to understanding environmental determinants of disease?

GD Smith et al.

INTERNATIONAL JOURNAL OF EPIDEMIOLOGY (2003)

Add to Collection

© Peeref 2019-2024. All rights reserved.