Breast-conserving surgery is an appropriate procedure for centrally located breast cancer: a population-based retrospective cohort study

Article Public, Environmental & Occupational Health

The relationship of marital adjustment and posttraumatic growth in female breast cancer patients and their husbands

Rongfei Suo et al.

Summary: Posttraumatic growth (PTG) is higher in breast cancer patients compared to their husbands, and marital adjustment has a positive predictive effect on the PTG of both patients and their husbands.

PSYCHOLOGY HEALTH & MEDICINE (2023)

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Article Surgery

Partial breast reconstruction of 30 cases with peri-mammary artery perforator flaps

Meiying Shen et al.

Summary: The study found that peri-mammary artery flaps are valuable in breast-conserving surgery, especially for patients with small or medium-sized breasts. Vascular ultrasound can be used to detect perforators before the operation, and more than one perforator can usually be found. With a suitable operation plan, no severe complications occurred, and patients were highly satisfied with the reconstruction technique, particularly AICAP and LICAP. Overall, this technique is suitable for partial breast reconstruction and does not negatively impact patient satisfaction.

BMC SURGERY (2023)

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Article Oncology

Association of body mass index with clinicopathological features and survival in patients with primary invasive lobular breast cancer

Karen Van Baelen et al.

Summary: In this study, the impact of body mass index (BMI) on the diagnosis and prognosis of invasive lobular carcinoma (ILC) was investigated. The results showed that higher BMI was associated with higher tumor grade, larger tumor size, nodal involvement, and multifocality. However, in multivariable analysis, BMI was not independently associated with prognosis, suggesting that its effect on survival may be mediated through its association with other clinicopathological variables.

EUROPEAN JOURNAL OF CANCER (2023)

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Article Surgery

Breast conservation therapy decreased heart-specific mortality in breast cancer patients compared with mastectomy

Zhi Li et al.

Summary: The aim of this study was to investigate the impacts of breast conservation therapy (BCT) and mastectomy on heart-specific mortality in breast cancer patients. Through follow-up and multivariate regression analysis of breast cancer patients, it was found that BCT significantly decreased heart-specific mortality compared with mastectomy.

BMC SURGERY (2023)

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Article Surgery

Breast conserving therapy for central breast cancer in the United States

Jiameng Liu et al.

Summary: This study evaluated the long-term survival outcomes of central breast cancer and found that breast-conserving therapy is safe and optional. The breast preservation rate increased from 39.9% in 2010 to 51% in 2015. In a matched case-control analysis, breast cancer-specific survival and overall survival were higher in the breast conserving therapy group compared to the non-breast conserving group. Subgroup analysis based on T staging and stage also showed higher overall survival and breast cancer-specific survival in the breast conserving therapy group.

BMC SURGERY (2022)

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Article Multidisciplinary Sciences

Chemotherapy significantly improves long-term survival of small lesion node negative metaplastic breast carcinoma in T1c population rather than T1a and T1b

Qitong Chen et al.

Summary: Metaplastic breast carcinoma (MpBC) is a highly aggressive disease, and the effect of chemotherapy on small lesions is unclear. This study found that chemotherapy improved the prognosis of T1c MpBC patients, but not T1a and T1b patients.

SCIENTIFIC REPORTS (2022)

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Article Surgery

Breast-conserving in centrally located breast cancer patients confirmed safe by SEER based study

Yu-Fei Shen et al.

Summary: Based on data from the SEER database, this study assessed the safety of breast-conserving surgery in patients with centrally located breast cancer. The results showed that there was no significant difference in disease-specific survival and overall survival between breast-conserving surgery for centrally located breast cancer and breast-conserving surgery for non-centrally located breast cancer.

GLAND SURGERY (2022)

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Article Oncology

Is breast conservation superior to mastectomy in early stage triple negative breast cancer?

Omran Saifi et al.

Summary: In patients with early-stage triple negative breast cancer, breast conservative therapy (BCT) followed by radiation therapy (RT) is associated with better overall survival (OS) and breast cancer-specific survival (BCSS) outcomes compared to mastectomy alone. However, specific patient subgroups, such as those older than 60 with any grade or T stage, may have better survival outcomes with lumpectomy and RT.

BREAST (2022)

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Article Oncology

Effect of the Nipple-Excising Breast-Conserving Therapy in Female Breast Cancer: A Competing Risk Analysis and Propensity Score Matching Analysis of Results Based on the SEER Database

Shouyu Li et al.

Summary: The study demonstrates that nipple-excising breast-conserving therapy is oncologically safe and reliable for women with non-metastatic breast cancer.

FRONTIERS IN ONCOLOGY (2022)

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Article Oncology

Breast Cancer, Version 3.2022

William J. Gradishar et al.

Summary: This article discusses the complex therapeutic options for patients with noninvasive or invasive breast cancer, as well as the recommendations provided by the NCCN Clinical Practice Guidelines for Breast Cancer. It focuses on the overall management of ductal carcinoma in situ and the workup and locoregional management of early stage invasive breast cancer.

JOURNAL OF THE NATIONAL COMPREHENSIVE CANCER NETWORK (2022)

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Article Oncology

Impact of Marital Status on Prognosis of Patients With Invasive Breast Cancer: A Population-Based Study Using SEER Database

Dechuang Jiao et al.

Summary: This study found that marital status is an independent prognostic factor for invasive breast cancer patients. Married patients have better survival rates compared to unmarried patients. Additional psychosocial and emotional support may be necessary for unmarried patients aged 35 and above in order to achieve longer survival.

FRONTIERS IN ONCOLOGY (2022)

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Article Oncology

Survival Outcomes of Breast-Conserving Therapy versus Mastectomy in Early-Stage Breast Cancer, Including Centrally Located Breast Cancer: A SEER-Based Study

Tianshui Yu et al.

Summary: This study aimed to analyze the survival outcomes of breast cancer patients, especially those with centrally located breast cancer, who underwent breast-conserving therapy or mastectomy. The results showed that breast-conserving therapy was favorable for breast cancer patients, including those with centrally located breast cancer.

BREAST JOURNAL (2022)

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Review Oncology

Accelerating drug development in breast cancer: New frontiers for ER inhibition

Emanuela Ferraro et al.

Summary: The paper discusses the importance of targeting ER signaling in controlling HR+ breast cancer, reviewing the clinical development of SERDs and other novel ER inhibitors. It emphasizes the significance of combination strategies and evaluates the advantages of newer oral ER inhibitors, as well as discussing future directions in the field.

CANCER TREATMENT REVIEWS (2022)

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Article Oncology

Customizing local and systemic therapies for women with early breast cancer: the St. Gallen International Consensus Guidelines for treatment of early breast cancer 2021

H. J. Burstein et al.

Summary: The 17th St Gallen International Breast Cancer Consensus Conference in 2021 was held virtually, with over 3300 participants discussing key issues related to early breast cancer diagnosis and treatment. The conference emphasized customized recommendations for breast cancer treatment, highlighting the importance of individualized clinical features in patient care.

ANNALS OF ONCOLOGY (2021)

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Article Oncology

Assessment of Ki67 in Breast Cancer: Updated Recommendations From the International Ki67 in Breast Cancer Working Group

Torsten O. Nielsen et al.

Summary: Ki67 immunohistochemistry (IHC) is commonly used in breast cancer as a proliferation marker, but its analytical validity has been questioned. The International Ki67 in Breast Cancer Working Group (IKWG) recommends careful preanalytical handling, adoption of a standardized visual scoring method, and participation in quality assurance and quality control programs. Clinical utility of Ki67 IHC in breast cancer care is currently limited to prognosis assessment in stage I or II breast cancer.

JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2021)

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Article Surgery

Outcomes of Asian Women Treated With Grisotti Flap Reconstruction for Centrally Located Breast Cancers 5-Years Single Institutional Experience

Mei-Sze Teh et al.

Summary: The Grisotti flap technique provides satisfactory cosmetic outcomes for centrally located breast cancer patients, with low rates of postoperative complications and a 100% overall survival rate. This technique offers an oncologically safe and aesthetically pleasing alternative for patients who would otherwise require mastectomy.

ANNALS OF PLASTIC SURGERY (2021)

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Article Oncology

The clinical features and prognosis of patients with mucinous breast carcinoma compared with those with infiltrating ductal carcinoma: a population-based study

Xingtong Zhou et al.

Summary: Compared with IDC, MBC has a better prognosis. Factors such as age ≥60 years, single status, and advanced TNM/SEER stage were identified as independent prognostic risk factors for MBC. Additionally, positive ER and PR, surgical treatment, and radiotherapy were identified as protective factors.

BMC CANCER (2021)

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Article Oncology

Breast-Conserving Therapy Has Better Prognosis for Tumors in the Central and Nipple Portion of Breast Cancer Compared with Mastectomy: A SEER Data-Based Study

Jing Wang et al.

Summary: The study demonstrates that breast-conserving therapy (BCT) exhibits superior prognosis in patients with tumors in the central and nipple portion (TCNP) compared to mastectomy therapy, across various subgroups such as age, sex, race, histological grade, AJCC stage, and molecular subtype. The findings suggest that BCT could be a preferred treatment option for suitable TCNP patients, especially those with a strong preference for breast conservation.

FRONTIERS IN ONCOLOGY (2021)

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Article Oncology