Vienna Cancer Stem Cell Club (VCSCC): 20 year jubilee and future perspectives

IntroductionThe Vienna Cancer Stem Cell Club (VCSCC) was launched by a group of scientists in Vienna in 2002.Areas coveredMajor aims of the VCSCC are to support research on cancer stem cells (CSC) in hematopoietic malignancies and to translate CSC-related markers and targets into clinical application. A primary focus of research in the VCSCC is the leukemic stem cell (LSC). Between 2013 and 2021, members of the VCSCC established a special research program on myeloproliferative neoplasms and since 2008, members of the VCSCC run the Ludwig Boltzmann Institute for Hematology and Oncology. In all these years, the VCSCC provided a robust intellectual platform for translational hematology and LSC research in Vienna. Furthermore, the VCSCC interacts with several national and international study groups and societies in the field. Representatives of the VCSCC also organized a number of international meetings and conferences on neoplastic stem cells, including LSC, in the past 15 years, and contributed to the definition and classification of CSC/LSC and related pre-malignant and malignant conditions.Expert opinionThe VCSCC will continue to advance the field and to develop LSC-detecting and LSC-eradicating concepts through which diagnosis, prognostication, and therapy of blood cancer patients should improve.

Automated summary

The Vienna Cancer Stem Cell Club (VCSCC) was established in 2002 to support research on cancer stem cells and translate it into clinical applications. Over the years, the VCSCC has made significant contributions in the field of hematopoietic malignancies and leukemic stem cell research, organizing international conferences and discussions.