Related references
Note: Only part of the references are listed.Female reproductive life span is extended by targeted removal of fibrotic collagen from the mouse ovary
Takashi Umehara et al.
SCIENCE ADVANCES (2022)
Oocytes mount a noncanonical DNA damage response involving APC-Cdh1-mediated proteolysis
Goutham Narayanan Subramanian et al.
JOURNAL OF CELL BIOLOGY (2020)
Oocytes can efficiently repair DNA double-strand breaks to restore genetic integrity and protect offspring health
Jessica M. Stringer et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)
Understanding the structure and role of DNA-PK in NHEJ: How X-ray diffraction and cryo-EM contribute in complementary ways
Qian Wu et al.
PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY (2019)
DNA damage and repair in the female germline: contributions to ART
Jacinta H. Martin et al.
HUMAN REPRODUCTION UPDATE (2019)
DNA Damage and Repair in Human Reproductive Cells
Anais Garcia-Rodriguez et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)
The capacity of oocytes for DNA repair
Jessica M. Stringer et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2018)
The importance of DNA repair for maintaining oocyte quality in response to anti-cancer treatments, environmental toxins and maternal ageing
Amy L. Winship et al.
HUMAN REPRODUCTION UPDATE (2018)
Oocyte stage-specific effects of MTOR determine granulosa cell fate and oocyte quality in mice
Jing Guo et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)
Double Strand Break DNA Repair occurs via Non-Homologous End-Joining in Mouse MII Oocytes
Jacinta H. Martin et al.
SCIENTIFIC REPORTS (2018)
Cyclin A2 modulates kinetochore-microtubule attachment in meiosis II
Qing-Hua Zhang et al.
JOURNAL OF CELL BIOLOGY (2017)
Non-homologous DNA end joining and alternative pathways to double-strand break repair
Howard H. Y. Chang et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2017)
DNA damage response during mouse oocyte maturation
Alexandra Mayer et al.
CELL CYCLE (2016)
DNA damage-induced metaphase I arrest is mediated by the spindle assembly checkpoint and maternal age
Petros Marangos et al.
NATURE COMMUNICATIONS (2015)
DNA damage induces a meiotic arrest in mouse oocytes mediated by the spindle assembly checkpoint
Josie K. Collins et al.
NATURE COMMUNICATIONS (2015)
Recessive mutations in POLR1C cause a leukodystrophy by impairing biogenesis of RNA polymerase III
Isabelle Thiffault et al.
NATURE COMMUNICATIONS (2015)
The Progeroid Phenotype of Ku80 Deficiency Is Dominant over DNA-PKCS Deficiency
Erwin Reiling et al.
PLOS ONE (2014)
Recent Insights into Spindle Function in Mammalian Oocytes and Early Embryos
Katie Howe et al.
BIOLOGY OF REPRODUCTION (2013)
Impairment of BRCA1-Related DNA Double-Strand Break Repair Leads to Ovarian Aging in Mice and Humans
Shiny Titus et al.
SCIENCE TRANSLATIONAL MEDICINE (2013)
Enhanced levels of double-strand DNA break repair proteins protect ovarian cancer cells against genotoxic stress-induced apoptosis
Rajkumar Singh Kalra et al.
JOURNAL OF OVARIAN RESEARCH (2013)
The DNA damage response in mammalian oocytes
John Carroll et al.
Frontiers in Genetics (2013)
Oocytes Progress beyond Prophase in the Presence of DNA Damage
Petros Marangos et al.
CURRENT BIOLOGY (2012)
Loss of a single allele for Ku80 leads to progenitor dysfunction and accelerated aging in skeletal muscle
Nathalie Didier et al.
EMBO MOLECULAR MEDICINE (2012)
DNA Double Strand Breaks but Not Interstrand Crosslinks Prevent Progress through Meiosis in Fully Grown Mouse Oocytes
Wai Shan Yuen et al.
PLOS ONE (2012)
Structural Basis of Type II Topoisomerase Inhibition by the Anticancer Drug Etoposide
Chyuan-Chuan Wu et al.
SCIENCE (2011)
DNA Topoisomerases and Their Poisoning by Anticancer and Antibacterial Drugs
Yves Pommier et al.
CHEMISTRY & BIOLOGY (2010)
γH2AX: a sensitive molecular marker of DNA damage and repair
L-J Mah et al.
LEUKEMIA (2010)
Significant correlation of species longevity with DNA double strand break recognition but not with telomere length
Antonello Lorenzini et al.
MECHANISMS OF AGEING AND DEVELOPMENT (2009)
DNA topoisomerase II and its growing repertoire of biological functions
John L. Nitiss
NATURE REVIEWS CANCER (2009)
Targeting DNA topoisomerase II in cancer chemotherapy
John L. Nitiss
NATURE REVIEWS CANCER (2009)
DNA-damage repair; the good, the bad, and the ugly
Razqallah Hakem
EMBO JOURNAL (2008)
Deletion of Ku70, Ku80, or both causes early aging without substantially increased cancer
Han Li et al.
MOLECULAR AND CELLULAR BIOLOGY (2007)
Three-dimensional structure of the human DNA-PKcs/Ku70/Ku80 complex assembled on DNA and its implications for DNA DSB repair
Laura Spagnolo et al.
MOLECULAR CELL (2006)
γ-H2AX dephosphorylation by protein phosphatase 2A facilitates DNA double-strand break repair
D Chowdhury et al.
MOLECULAR CELL (2005)
Stops and starts in mammalian oocytes: recent advances in understanding the regulation of meiotic arrest and oocyte maturation
LM Mehlmann
REPRODUCTION (2005)
The evolution of meiosis: recruitment and modification of somatic DNA-repair proteins
E Marcon et al.
BIOESSAYS (2005)
The role of DNA breaks in genomic instability and tumorigenesis
KD Mills et al.
IMMUNOLOGICAL REVIEWS (2003)
Differential expression of DNA nonhomologous end-joining proteins Ku70 and Ku80 in melanoma progression
M Korabiowska et al.
MODERN PATHOLOGY (2002)
Structure of the Ku heterodimer bound to DNA and its implications for double-strand break repair
JR Walker et al.
NATURE (2001)
DNA repair protein Ku80 suppresses chromosomal aberrations and malignant transformation
MJ Difilippantonio et al.
NATURE (2000)