Journal
BMC NEPHROLOGY
Volume 24, Issue 1, Pages -Publisher
BMC
DOI: 10.1186/s12882-023-03079-4
Keywords
Rituximab; Hypokalemia; Nephrotic syndrome
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This article reports two cases of symptomatic hypokalemia after intravenous rituximab administration, reminding healthcare professionals to consider the possibility of acute hypokalemia after rituximab administration, monitor potassium levels timely, and develop an appropriate treatment plan.
Rituximab, a chimeric anti-CD20 monoclonal antibody, is an effective treatment for nephrotic syndrome. Hypokalemia is a rare adverse reaction among patients treated with rituximab although there have been extensive reports of acute and chronic adverse events with the administration of rituximab. We herein report two cases of symptomatic hypokalemia after intravenous rituximab administration in our center, to help health professionals consider the possibility of acute hypokalemia after rituximab administration, monitor potassium timely and develop an appropriate treatment plan.
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