Journal
VIRUSES-BASEL
Volume 15, Issue 7, Pages -Publisher
MDPI
DOI: 10.3390/v15071442
Keywords
PRRSV; persistent infection; adaptive immunity; non-neutralizing antibodies
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Since its discovery, Porcine reproductive and respiratory syndrome (PRRS) has had a significant impact on the farming industry. The virus responsible for PRRS is Porcine Reproductive and Respiratory Syndrome Virus (PRRSV), and its eradication has proven to be challenging due to its genetic diversity and the complexity of the immune response. This study provides scientific insights into PRRSV-induced infection and escape, as well as the host's adaptive immune response to PRRSV, aiming to contribute to PRRSV control and vaccine development.
Since its discovery, Porcine reproductive and respiratory syndrome (PRRS) has had a huge impact on the farming industry. The virus that causes PRRS is Porcine Reproductive and Respiratory Syndrome Virus (PRRSV), and because of its genetic diversity and the complexity of the immune response, the eradication of PRRS has been a challenge. To provide scientific references for PRRSV control and vaccine development, this study describes the processes of PRRSV-induced infection and escape, as well as the host adaptive immune response to PRRSV. It also discusses the relationship between PRRSV and the adaptive immune response.
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