Related references
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Review
Virology
Ioana Grigore et al.
Summary: In this case report, the authors describe a teenager who developed persistent right side hemicrania, nausea, and vomiting on the 5th day of quarantine after SARS-CoV-2 infection. Neuroimaging revealed cerebral venous thrombosis affecting multiple veins. The patient showed improvement with anticoagulant and symptomatic treatment, and other causes of thrombosis were ruled out by laboratory tests. The authors suggest that cerebral thrombosis could be a possible complication of SARS-CoV-2 infection in teenagers.
Article
Virology
Anna Gloria Fonseca Teodoro et al.
Summary: COVID-19 infection can lead to a wide range of clinical presentations and predisposition to thromboembolic disease due to excessive inflammation. This study aimed to characterize the clinical and laboratory aspects of hospitalized patients and analyze the serum cytokine pattern associated with thromboembolic events. A retrospective cohort study of 97 COVID-19 patients revealed 7 cases of thrombotic occurrence. The thrombus group showed a reduction in prothrombin activity and 27.8% of all patients had thrombocytopenia. Higher levels of IL-1β, IL-10, and IL-2 were observed in the group with thrombotic events. The study found an increase in inflammatory response and a link between IL-10 percentage and the likelihood of thrombotic events.
Article
Virology
Rosilene da Silva et al.
Summary: This study aimed to evaluate the role of ten functional polymorphisms in long COVID and found that these polymorphisms were associated with genetic susceptibility to long COVID among LC patients.
Review
Virology
Christian A. Devaux et al.
Summary: The benefits of SARS-CoV-2 spike mRNA vaccines are well known, but there have been rare cases of cardiovascular complications and high blood pressure reported. This has raised concerns about the safety of COVID-19 vaccines. The observed harmful effects may be due to a dysregulation of ACE2 function and molecular mimicry of the viral spike. It is recommended to have medical surveillance for patients with a history of cardiovascular diseases who receive the COVID-19 vaccine.
Article
Virology
Antonio Lobasso et al.
Summary: Since the COVID-19 outbreak, there has been a noted association between COVID-19 and thrombotic diseases. Ischaemic stroke has been reported as a thrombotic complication in affected patients and is considered a risk factor for early mortality. The use of sotrovimab, a neutralizing monoclonal antibody against SARS-CoV-2, has shown promise in treating high-risk patients with mild-to-moderate COVID-19, reducing the risk of disease progression. However, we report a rare case of ischaemic stroke occurring shortly after the administration of sotrovimab in a frail patient with chronic lymphocytic leukaemia for the first time.
Review
Virology
Cristian-Mihail Niculae et al.
Summary: The rate of thrombotic complications in COVID-19 patients is high and not influenced by traditional risk factors. Pulmonary thrombotic events are more related to inflammation, and treatment should take this aspect into consideration.
Article
Virology
Chiara Rubino et al.
Summary: This study assessed the prevalence of thromboembolic events (TEs) in children hospitalized during a five-year period, particularly in patients with COVID-19 and MIS-C. The occurrence of TEs was higher in patients with COVID-19 or MIS-C compared to children without these conditions. The prevalence of TEs was significantly higher in patients with MIS-C.
Article
Virology
Anastasiya S. Babkina et al.
Summary: COVID-19-related thrombosis, especially pulmonary artery thrombosis, is associated with prolonged hospital stay, neutrophil infiltration in the alveolar spaces, and the absence of hyaline membranes. Neutrophil infiltration and the absence of hyaline membranes are independent predictors of pulmonary artery thrombosis, indicating a later occurrence in the course of COVID-19 infection. Bacterial infections should be considered in critically ill patients based on the presence of neutrophil infiltration in the alveolar spaces.
Editorial Material
Virology
Ciro di Gennaro et al.
